CA2674296C - Non-immunosuppressive cyclosporin for treatment of ullrich congenital muscular dystrophy - Google Patents

Non-immunosuppressive cyclosporin for treatment of ullrich congenital muscular dystrophy Download PDF

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Publication number
CA2674296C
CA2674296C CA2674296A CA2674296A CA2674296C CA 2674296 C CA2674296 C CA 2674296C CA 2674296 A CA2674296 A CA 2674296A CA 2674296 A CA2674296 A CA 2674296A CA 2674296 C CA2674296 C CA 2674296C
Authority
CA
Canada
Prior art keywords
meala
meleu
cyclosporin
csa
etval
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2674296A
Other languages
English (en)
French (fr)
Other versions
CA2674296A1 (en
Inventor
Paolo Bernardi
Gregoire Vuagniaux
Rafael Crabbe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Debiopharm International SA
Original Assignee
Debiopharm International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm International SA filed Critical Debiopharm International SA
Publication of CA2674296A1 publication Critical patent/CA2674296A1/en
Application granted granted Critical
Publication of CA2674296C publication Critical patent/CA2674296C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2674296A 2007-01-04 2008-01-03 Non-immunosuppressive cyclosporin for treatment of ullrich congenital muscular dystrophy Expired - Fee Related CA2674296C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87841407P 2007-01-04 2007-01-04
USUS60/878,414 2007-01-04
PCT/IB2008/000003 WO2008084368A2 (en) 2007-01-04 2008-01-03 Non-immunosuppressive cyclosporin for treatment of ullrich congenital muscular dystrophy

Publications (2)

Publication Number Publication Date
CA2674296A1 CA2674296A1 (en) 2008-07-17
CA2674296C true CA2674296C (en) 2015-11-24

Family

ID=39514754

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2674296A Expired - Fee Related CA2674296C (en) 2007-01-04 2008-01-03 Non-immunosuppressive cyclosporin for treatment of ullrich congenital muscular dystrophy

Country Status (12)

Country Link
US (1) US8450281B2 (cg-RX-API-DMAC7.html)
EP (1) EP2124992A2 (cg-RX-API-DMAC7.html)
JP (1) JP5801534B2 (cg-RX-API-DMAC7.html)
CN (2) CN105056207A (cg-RX-API-DMAC7.html)
AU (1) AU2008204344B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0806265A2 (cg-RX-API-DMAC7.html)
CA (1) CA2674296C (cg-RX-API-DMAC7.html)
HK (1) HK1210951A1 (cg-RX-API-DMAC7.html)
IL (1) IL199674A (cg-RX-API-DMAC7.html)
MX (1) MX2009007045A (cg-RX-API-DMAC7.html)
RU (1) RU2462262C2 (cg-RX-API-DMAC7.html)
WO (1) WO2008084368A2 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009098533A1 (en) * 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy
WO2011098808A1 (en) 2010-02-09 2011-08-18 Biotica Technology Limited Sanglifehrin based compounds
MX2012008873A (es) 2010-02-09 2012-11-22 Biotica Tech Ltd Compuestos a base de sangliferina.
WO2011098805A1 (en) 2010-02-09 2011-08-18 Biotica Technology Limited Sanglifehrin based compounds
GB201008123D0 (en) 2010-05-17 2010-06-30 Biotica Tech Ltd Novel compounds
WO2012085553A1 (en) 2010-12-20 2012-06-28 Biotica Technology Limited Sanglifehrin derivatives and methods for their production
JO3063B1 (ar) 2011-03-29 2017-03-15 Neurovive Pharmaceutical Ab مركب مبتكر وطرق لانتاجه
WO2013169616A1 (en) 2012-05-07 2013-11-14 Novartis Ag Pharmacokinetic modulation with alisporivir
AR090964A1 (es) 2012-05-09 2014-12-17 Novartis Ag Proceso para la elaboracion de undecapeptidos ciclicos

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3884470T2 (de) * 1987-06-17 1994-03-10 Sandoz Ag Cyclosporine und deren Benutzung als Arzneimittel.
GB2222770B (en) 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
AU3965699A (en) * 1998-04-24 1999-11-16 Mitokor Compounds and methods for treating mitochondria-associated diseases
EP1091975B1 (fr) * 1998-07-01 2005-12-14 Debiopharm S.A. Nouvelle cyclosporine ayant un profil d'activite ameliore
US6323039B1 (en) * 1999-06-22 2001-11-27 Mitokor Compositions and methods for assaying subcellular conditions and processes using energy transfer
US7368423B1 (en) 2001-12-05 2008-05-06 The Scripps Research Institute Composition and method for treating chronic allograft rejection
GB0320638D0 (en) * 2003-09-03 2003-10-01 Novartis Ag Organic compounds
WO2009098533A1 (en) * 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy

Also Published As

Publication number Publication date
IL199674A0 (en) 2010-04-15
JP2010514834A (ja) 2010-05-06
AU2008204344A9 (en) 2012-06-28
BRPI0806265A2 (pt) 2011-09-06
AU2008204344B2 (en) 2013-01-31
EP2124992A2 (en) 2009-12-02
HK1210951A1 (en) 2016-05-13
WO2008084368A9 (en) 2009-02-26
RU2462262C2 (ru) 2012-09-27
IL199674A (en) 2016-10-31
CA2674296A1 (en) 2008-07-17
US20100041593A1 (en) 2010-02-18
WO2008084368A8 (en) 2009-09-17
RU2009129212A (ru) 2011-02-10
MX2009007045A (es) 2009-10-07
JP5801534B2 (ja) 2015-10-28
CN101616683A (zh) 2009-12-30
US8450281B2 (en) 2013-05-28
CN105056207A (zh) 2015-11-18
WO2008084368A2 (en) 2008-07-17
AU2008204344A1 (en) 2008-07-17

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Legal Events

Date Code Title Description
EEER Examination request
EEER Examination request

Effective date: 20121210

MKLA Lapsed

Effective date: 20200103