CN101606904A - The preparation method of sodium bicarbonate solution gynecological lotion - Google Patents
The preparation method of sodium bicarbonate solution gynecological lotion Download PDFInfo
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- CN101606904A CN101606904A CNA2008101270318A CN200810127031A CN101606904A CN 101606904 A CN101606904 A CN 101606904A CN A2008101270318 A CNA2008101270318 A CN A2008101270318A CN 200810127031 A CN200810127031 A CN 200810127031A CN 101606904 A CN101606904 A CN 101606904A
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- sodium bicarbonate
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- bicarbonate solution
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Abstract
The preparation method of sodium bicarbonate solution gynecological lotion.Method for making is two kinds, be respectively one: in weight portion, medicinal sodium bicarbonate 1-10 part, 100 parts in water, preferred component is 5 parts of sodium bicarbonate, 100 parts in water, through dissolving, filter, sterilization, fill obtains product, and is another kind of for sodium bicarbonate is made effervescent tablet, and the time spent adds the purified water dissolving and obtains lotion, be specially: sodium bicarbonate 85-95 part, PVP3-10 part, magnesium stearate 2-5 part, solvent is a water, through sieving, weighing, granulate, mix, dry, tabletting, pack this product, product of the present invention belongs to gynecological's auxiliary treatment medication, can improve the pH value of vagina, treatment women colpitis mycotica, this product manufacturing is simple, use, it is convenient to store, long shelf-life.
Description
Technical field
The present invention relates to a kind of Amino-Cerv,,, diminish inflammation, simultaneously, the invention still further relates to two kinds of methods of this medicament preparation by destroying the growing environment kill bacteria of mycete in particular to a kind of vagina PH value that improves the colpitis mycotica patient.
Background technology
The sodium bicarbonate preparation has a variety of; as tablet; injection; dosage forms such as solution; but be respectively applied for oral anti-gastric acid more; alkalized urine; correct acidosis; rinse; the flushing eye is fine etc.; and the lotion that is used for gynecological does not at present have; I once visited the gynecological of Pekinese's six large hospitals; the rate of falling ill of colpitis mycotica is very high; and be preparation at that time in the flushing of gynecological; use a balance; the rustless steel open bottles of the one band latex tubing that can hang; weigh in the balance and decide to pour in the bottle behind the fixed sodium bicarbonate of title; add a certain amount of purified water; hang up promptly after the stirring and use; this way is not cannot; but several shortcomings are arranged; one; the environmental health of making is poor; there is not clean rank; gynecology colpitis own is exactly a bacterial inflammation; other pathogenic bacteria of easy infection more; two; the weighing apparatus that uses is unhygienic; three; patient is in row group, and the makers-up takes time and energy very much, when exchanging with doctors respectively; they wish to have the preparation that has prepared to provide together; wherein the director of gynecological of united family hospital, Beijing returns our suggestion and puts into production as soon as possible, and reasonable device of said preparation bottling or the like is provided, through groping more than 3 years; we from lab scale to big production; the experiment of long-time stability from the accelerated tests to the product, we be through with this product a series of experiments and be produced on a large scale, the listing of said preparation can make things convenient for hospital; also make things convenient for the patient to use simultaneously at home, main is to make the application of product safer; fast.
Summary of the invention
The Preparation method and use that the purpose of this invention is to provide two kinds of sodium bicarbonate solution gynecological lotions, product economy of the present invention, safety are carried, easy to use, and long shelf-life is the Amino-Cerv of ideal change vagina acid-base value
The wherein technical scheme one that the invention provides two kinds of preparation methoies is: in weight portion, and medicinal sodium bicarbonate 1-6 part, 100 parts in water, preferred component is sodium bicarbonate 3-5 part, 100 parts in water obtains product through dissolving, filtration, sterilization, fill
Another kind of for sodium bicarbonate is made effervescent tablet, the time spent adds the purified water dissolving and obtains lotion, is specially: sodium bicarbonate 85-95 part, PVP3-10 part, magnesium stearate 2-5 part
1) the sodium bicarbonate raw material was pulverized 80 orders, precision takes by weighing 95 parts of raw materials,
2) make binding agent with 10% PVP, granulate
3) drying
4) add 3 parts of magnesium stearate and make fluidizer, mix
5) tabletting
6) packing
Advantage of the present invention: product health of the present invention, economical, convenient, also enlarged the scope of application, the auxiliary treatment that not only can be used for gynecological, also can be used as simultaneously the antacid that hyperchlorhydria causes, the medicine of alkalized urine, ophthalmology flushing lotion, low concentration can also as soda water become people need with the alkalescence beverage drink, improve the alkalescence of human body, health invigorating or the like, can be used for food, drinks, and drug class use, but specification, packing, operation instructions etc. must be pressed food respectively, the different purposes of functional drinks and medicine are made respectively, packing.
The specific embodiment
Detailed description below by the specific embodiment is further illustrated the present invention, but is not limitation of the present invention, only does the example explanation.
Embodiment one
Preparation sodium bicarbonate gynecological lotion, step is carried out in the following order:
1) the medicinal raw material sodium bicarbonate was pulverized 80 mesh sieves, took by weighing 1.5 kilograms, added the purified water double centner by prescription
2) stirring makes its dissolving
3) filter
4) sterilize in 100 ℃ of-135 ℃ of scopes with the instantaneous ultrahigh-temperature sterilization method
5) fill promptly gets concentration and is 1.5% product, and general 10-1000 milliliter is pressed the fill of different size demand and got final product
It is that humidifying air flue desaturation sputum is treated that product under 1.5% concentration that present embodiment makes can be used for
Embodiment two
Preparation sodium bicarbonate gynecological lotion, step is carried out in the following order:
1) the medicinal raw material sodium bicarbonate was pulverized 80 mesh sieves, took by weighing 3 kilograms, added the purified water double centner by prescription
2) stirring makes its dissolving
3) filter
4) sterilize in 100 ℃ of-135 ℃ of scopes with the instantaneous ultrahigh-temperature sterilization method
5) fill promptly gets concentration and is 3% product, and general 10-1000 milliliter is pressed the fill of different size demand and got final product
After present embodiment makes product under 3% concentration and is usually used in being colpitis mycotica patient demibain, the adjuvant drug that uses in families such as putting into vagina sterilization medication.
Embodiment three
Preparation sodium bicarbonate gynecological lotion, step is carried out in the following order:
1) the medicinal raw material sodium bicarbonate was pulverized 80 mesh sieves, took by weighing 4 kilograms, added the purified water double centner by prescription
2) stirring makes its dissolving
3) filter
4) sterilize in 100 ℃ of-135 ℃ of scopes with the instantaneous ultrahigh-temperature sterilization method
5) fill promptly gets concentration and is 4% product, and general 10-1000 milliliter is pressed the fill of different size demand and got final product
The product that present embodiment makes under 4% concentration is usually used in treating children's's moniliasis white mouth, but the present invention is mainly used to treat colpitis mycotica.
Embodiment four
Preparation sodium bicarbonate gynecological lotion, step is carried out in the following order:
1) the medicinal raw material sodium bicarbonate was pulverized 80 mesh sieves, took by weighing 5.6 kilograms, added the purified water double centner by prescription
2) stirring makes its dissolving
3) filter
4) sterilize in 100 ℃ of-135 ℃ of scopes with the instantaneous ultrahigh-temperature sterilization method
5) fill promptly gets concentration and is 5.6% product, and general 10-1000 milliliter press the different size demand and bottled and get final product
The product that present embodiment makes under 5.6% concentration is usually used in not only can be used for gynecological's auxiliary treatment flushing, also is being used for porcine epizootic diarrhea diagnostic techniques etc.
Embodiment five
Effervescent tablet
1) respectively with raw material pulverizing, cross 80 orders, get 90 parts of sodium bicarbonate then, 3 parts of magnesium stearate.
2) make binding agent with 10% PVP, sodium bicarbonate is granulated
3) drying
4) add 3 parts of magnesium stearate and make fluidizer, mix homogeneously
5) tabletting, sheet heavily are 1.12g, and every agreement that contracts a film or TV play to an actor or actress contains sodium bicarbonate 1g
6) packing
Embodiment six
Effervescent tablet
1) respectively with raw material pulverizing, cross 80 orders, get 95 parts of sodium bicarbonate then, 2 parts of magnesium stearate.
2) make binding agent with 10% PVP, sodium bicarbonate is granulated
3) drying
4) add 3 parts of magnesium stearate and make fluidizer, mix homogeneously
5) tabletting, sheet heavily are 1.05g, and every agreement that contracts a film or TV play to an actor or actress contains sodium bicarbonate 1g
6) packing
This product not only can be made the lotion of variable concentrations as required, also can be oral as antacid, under physician guidance, take.
Claims (6)
1, the preparation method one of sodium bicarbonate solution gynecological lotion is characterized in that: in weight portion sodium bicarbonate raw material is 1-6 part, 100 parts in water.
2, sodium bicarbonate solution gynecological lotion according to claim 1 is characterized in that: optimization formula is in weight portion, 100 parts in 5 parts of its medicinal raw material components and water.
3, the preparation method of sodium bicarbonate solution gynecological lotion according to claim 1 comprises following sequential steps:
1) the medicinal raw material sodium bicarbonate is crossed 80 mesh sieves, it is fixed to claim by prescription
2) add the entry stirring and make its dissolving;
3) filter
4) sterilize in 100 ℃ of-135 ℃ of scopes with the instantaneous ultrahigh-temperature sterilization method
5) fill.
4, the sodium bicarbonate solution gynecological lotion preparation method two, it is characterized in that; In weight portion sodium bicarbonate 85-95 part, PVP3-10 part, magnesium stearate 2-5 part.
5, sodium bicarbonate solution gynecological lotion according to claim 4 is characterized in that: optimization formula is for being 95 parts in the weight portion sodium bicarbonate, and magnesium stearate is 3 parts, and PVP is 2 parts.
6, the preparation method of sodium bicarbonate solution gynecological lotion according to claim 4 comprises following sequential steps:
1) the sodium bicarbonate raw material was pulverized 80 orders, 95 parts of raw materials decided in accurate title,
2) make binding agent with 10% PVP, granulate
3) drying
4) add 3 parts of magnesium stearate and make fluidizer, mix
5) tabletting
6) packing
Because of sodium bicarbonate this as a kind of effervescent, so need not add effervescent again, the time spent, add slice, thin piece and purified water gets final product by desired concn requirements, can from 1% to 6% demand of pressing prepare.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101270318A CN101606904A (en) | 2008-06-18 | 2008-06-18 | The preparation method of sodium bicarbonate solution gynecological lotion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101270318A CN101606904A (en) | 2008-06-18 | 2008-06-18 | The preparation method of sodium bicarbonate solution gynecological lotion |
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|---|---|
| CN101606904A true CN101606904A (en) | 2009-12-23 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008101270318A Pending CN101606904A (en) | 2008-06-18 | 2008-06-18 | The preparation method of sodium bicarbonate solution gynecological lotion |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102750999A (en) * | 2012-07-18 | 2012-10-24 | 山东电力集团公司烟台供电公司 | Anti-corrosion resistance reduction agent for copper ground grid |
| CN102988411A (en) * | 2012-11-27 | 2013-03-27 | 顾月燕 | Preparation method of gynecological lotion |
-
2008
- 2008-06-18 CN CNA2008101270318A patent/CN101606904A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102750999A (en) * | 2012-07-18 | 2012-10-24 | 山东电力集团公司烟台供电公司 | Anti-corrosion resistance reduction agent for copper ground grid |
| CN102750999B (en) * | 2012-07-18 | 2013-10-16 | 国家电网公司 | Anti-corrosion resistance reduction agent for copper ground grid |
| CN102988411A (en) * | 2012-11-27 | 2013-03-27 | 顾月燕 | Preparation method of gynecological lotion |
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Open date: 20091223 |