CN1015963B - 微包囊的制法 - Google Patents

微包囊的制法

Info

Publication number
CN1015963B
CN1015963B CN87108128A CN87108128A CN1015963B CN 1015963 B CN1015963 B CN 1015963B CN 87108128 A CN87108128 A CN 87108128A CN 87108128 A CN87108128 A CN 87108128A CN 1015963 B CN1015963 B CN 1015963B
Authority
CN
China
Prior art keywords
wax
protein
particle
microcyst
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CN87108128A
Other languages
English (en)
Chinese (zh)
Other versions
CN87108128A (zh
Inventor
相静夫
高桥义人
小濑村政树
大川原正明
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ohkawara Kokohki Co Ltd
Original Assignee
Ohkawara Kokohki Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohkawara Kokohki Co Ltd filed Critical Ohkawara Kokohki Co Ltd
Publication of CN87108128A publication Critical patent/CN87108128A/zh
Publication of CN1015963B publication Critical patent/CN1015963B/zh
Expired legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5015Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5052Proteins, e.g. albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/04Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/06Making microcapsules or microballoons by phase separation
    • B01J13/12Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S426/00Food or edible material: processes, compositions, and products
    • Y10S426/805Pet food for dog, cat, bird, or fish
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Medicinal Preparation (AREA)
CN87108128A 1986-12-15 1987-12-15 微包囊的制法 Expired CN1015963B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP298366/86 1986-12-15
JP61298366A JPS63151353A (ja) 1986-12-15 1986-12-15 ワツクスコ−テイングマイクロカプセルの製造方法

Publications (2)

Publication Number Publication Date
CN87108128A CN87108128A (zh) 1988-07-13
CN1015963B true CN1015963B (zh) 1992-03-25

Family

ID=17858758

Family Applications (1)

Application Number Title Priority Date Filing Date
CN87108128A Expired CN1015963B (zh) 1986-12-15 1987-12-15 微包囊的制法

Country Status (6)

Country Link
US (1) US4943449A (enExample)
EP (1) EP0275358B1 (enExample)
JP (1) JPS63151353A (enExample)
KR (1) KR950002149B1 (enExample)
CN (1) CN1015963B (enExample)
DE (1) DE3777141D1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0777964B1 (en) * 1989-08-30 2001-11-14 Kynoch Agrochemicals (Proprietary) Limited Preparation of a dosage device
FR2660554B1 (fr) * 1990-04-05 1992-07-03 Oreal Composition cosmetique ou dermo-pharmaceutique aqueuse contenant en suspension des spherouides hydrates d'une substance lipidique hydrophile.
US5102402A (en) 1991-01-04 1992-04-07 Medtronic, Inc. Releasable coatings on balloon catheters
JP2553258B2 (ja) * 1991-05-20 1996-11-13 三菱化学株式会社 ワックス被覆製剤の製造方法
US5250236A (en) * 1991-08-05 1993-10-05 Gasco Maria R Method for producing solid lipid microspheres having a narrow size distribution
US5160742A (en) * 1991-12-31 1992-11-03 Abbott Laboratories System for delivering an active substance for sustained release
US5571166A (en) * 1992-03-19 1996-11-05 Medtronic, Inc. Method of making an intraluminal stent
US5591224A (en) * 1992-03-19 1997-01-07 Medtronic, Inc. Bioelastomeric stent
US5510077A (en) * 1992-03-19 1996-04-23 Dinh; Thomas Q. Method of making an intraluminal stent
US5599352A (en) * 1992-03-19 1997-02-04 Medtronic, Inc. Method of making a drug eluting stent
AU682827B2 (en) * 1992-09-18 1997-10-23 Astellas Pharma Inc. Sustained-release hydrogel preparation
ATE246039T1 (de) * 1997-09-09 2003-08-15 Select Release L C Beschichtete teilchen, methode zu ihrer herstellung und verwendung
DE10007322A1 (de) * 2000-02-17 2001-08-23 Cognis Deutschland Gmbh Perlglanzmittel
CA2424619C (en) * 2000-10-04 2010-05-18 Kyowa Hakko Kogyo Co., Ltd. Method for coating fine particles with lipid membrane
EP1243326A1 (de) * 2001-03-22 2002-09-25 Cognis Iberia, S.L. Nanokapseln (II)
ES2187380A1 (es) * 2001-11-16 2003-06-01 Sanchez Juan Balufo Mejoras introducidas en productos destinados al consumo humano o animal.
US20040043070A1 (en) * 2002-05-14 2004-03-04 Ayres James W. Hot melt coating by direct blending and coated substrates
CN101612542A (zh) * 2005-01-28 2009-12-30 协和发酵麒麟株式会社 被覆微粒的制备方法
US9050393B2 (en) * 2005-02-08 2015-06-09 Bruce N. Saffran Medical devices and methods for modulation of physiology using device-based surface chemistry
US7828840B2 (en) * 2007-11-15 2010-11-09 Med Institute, Inc. Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists
CN102125171A (zh) * 2010-01-12 2011-07-20 杭州康德权饲料有限公司 一种微囊化包膜氧化锌的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857933A (en) * 1969-10-17 1974-12-31 Hoechst Ag Process for the manufacture of a drug dosage form permitting controlled release of active ingredient
CA923384A (en) * 1970-02-03 1973-03-27 Abe Jinnosuke Process for preparing a micro capsule
JPS49107855A (enExample) * 1973-02-03 1974-10-14
GB1413186A (en) * 1973-06-27 1975-11-12 Toyo Jozo Kk Process for encapsulation of medicaments
JPS5231981A (en) * 1975-08-18 1977-03-10 Takeda Chem Ind Ltd Microcapsule preparation method
JPS5619324A (en) * 1979-07-24 1981-02-24 Asahi Electronics Wheel passage type anchoring clamp
JPS56140915A (en) * 1980-04-07 1981-11-04 Yamanouchi Pharmaceut Co Ltd Pharmaceutical preparation for solid drug
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
FR2526328A1 (fr) * 1982-05-04 1983-11-10 Centre Nat Rech Scient Microcapsules a paroi obtenue par reticulation des proteines du lait, et leur procede de preparation
JPS61174940A (ja) * 1985-01-29 1986-08-06 Oogawara Kakoki Kk ワックス類コーテイング単核状マイクロカプセルおよびその製造方法
JPH078659B2 (ja) * 1988-07-18 1995-02-01 株式会社クボタ トラクタのエンジンボンネット取付構造

Also Published As

Publication number Publication date
KR880007067A (ko) 1988-08-26
KR950002149B1 (ko) 1995-03-14
CN87108128A (zh) 1988-07-13
EP0275358A1 (en) 1988-07-27
US4943449A (en) 1990-07-24
DE3777141D1 (de) 1992-04-09
JPS63151353A (ja) 1988-06-23
EP0275358B1 (en) 1992-03-04
JPH0533095B2 (enExample) 1993-05-18

Similar Documents

Publication Publication Date Title
CN1015963B (zh) 微包囊的制法
JP2582186B2 (ja) カプセル封じ法及びその製品
CA1164800A (en) Vitamin encapsulation
CN1118319C (zh) 通过受控制的水输送将香料和香味剂包入微胶囊的方法
RU2145211C1 (ru) Способ получения сферических частиц на основе активного начала
KAWATA et al. Preparation and dissolution pattern of Eudragit RS microcapsules containing ketoprofen
US8034450B2 (en) Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
JPH10502621A (ja) 親油性物質の多重マイクロカプセル封入
HK1052304A1 (zh) 微囊化的方法
CN103752236A (zh) 一种双层包覆香精微胶囊的制备方法
US5030391A (en) Process for the production of spherical particles of ceramics
JPH06503259A (ja) コラーゲン粒子の製造法及びその活性基質に対する担体としての使用法
CN1942239A (zh) 油的凝聚囊化法
CN114190507A (zh) 一种以木薯淀粉无醇酯化混合物为壁材制备精油微胶囊的方法
CN113827577B (zh) 一种岩藻黄质微胶囊及其制备方法
JP5575395B2 (ja) 沈降によってカプセル化物を製造する方法
CN1274296C (zh) 由难溶化合物制备水分散性干粉的方法
Atkins et al. The incorporation and release of bovine serum albumin from poly-hydroxybutyrate-hydroxyvalerate microcapsules
JP2611993B2 (ja) マイクロカプセルとその製造方法
US4743583A (en) Sustained release protein compositions and method for making
EP0085079B1 (en) Microencapsulation process
EP1605917A1 (en) Process for the production of cross-linked gelatin microbeadlets
JP2713579B2 (ja) マイクロカプセル化アスコルビン酸の製造方法
CN1082068A (zh) 双水相乳化法制备的微珠及其制备方法
RU2296615C2 (ru) Способ капсулирования растворенного компонента цветных реакций систем цветных реакций, полученные капсулы и их применение в бумаге для цветных реакций

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C13 Decision
GR02 Examined patent application
C14 Grant of patent or utility model
GR01 Patent grant
C15 Extension of patent right duration from 15 to 20 years for appl. with date before 31.12.1992 and still valid on 11.12.2001 (patent law change 1993)
OR01 Other related matters
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee