CN101590184B - 一种用于治疗痛风的中药组合物及其制备方法 - Google Patents
一种用于治疗痛风的中药组合物及其制备方法 Download PDFInfo
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Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103830621A (zh) * | 2014-03-14 | 2014-06-04 | 李宏伟 | 一种治疗痛风的中草药配方及其制备方法 |
CN104082743A (zh) * | 2014-07-09 | 2014-10-08 | 刘友章 | 一种用于治疗急性痛风性关节炎的保健食品及其制备方法 |
CN105582422A (zh) * | 2016-03-21 | 2016-05-18 | 济南正骐生物科技有限公司 | 一种治疗痛风的中药及其制备方法 |
CN105853811A (zh) * | 2016-06-02 | 2016-08-17 | 罗汉武 | 一种治疗尿酸偏高的中药组合物 |
CN113521215A (zh) * | 2021-08-19 | 2021-10-22 | 威海德尚医中医药科技有限公司 | 一种降尿酸缓解尿酸结晶的中药提纯物及其制备方法 |
CN114028511B (zh) * | 2021-12-17 | 2022-11-08 | 南京中医药大学 | 一种治疗难治性痛风的中药组合物及其应用 |
CN114404538B (zh) * | 2022-03-01 | 2022-12-13 | 复旦大学附属金山医院(上海市金山区眼病防治所、上海市金山区核化伤害应急救治中心) | 一种治疗痛风性关节炎的中药组合物及其应用 |
Citations (2)
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CN1803177A (zh) * | 2005-01-11 | 2006-07-19 | 贵阳新天药业股份有限公司 | 一种治疗痛风的中药组合物及制备方法 |
CN1814220A (zh) * | 2005-11-23 | 2006-08-09 | 安徽省药物研究所 | 治疗痛风病的药物及其制备方法 |
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CN1803177A (zh) * | 2005-01-11 | 2006-07-19 | 贵阳新天药业股份有限公司 | 一种治疗痛风的中药组合物及制备方法 |
CN1814220A (zh) * | 2005-11-23 | 2006-08-09 | 安徽省药物研究所 | 治疗痛风病的药物及其制备方法 |
Non-Patent Citations (2)
Title |
---|
呼永河等.急性痛风性关节炎中医治法研究近况.《中国中医急症》.2007,第16卷(第11期),1399-1401. * |
杨春山等.清热利湿解毒法治疗急性痛风性关节炎68例.《长春中医学院学报》.2001,第17卷(第4期),16. * |
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Address after: 100088 Beijing city Xicheng District, New Street No. 2 Tiancheng Technology building block B room 3003 Patentee after: BEIJING INCREASE PHARMACEUTICAL INSTITUTE Co.,Ltd. Address before: 100088 Beijing city Xicheng District, New Street No. 2 Tiancheng Technology building block B room 3003 Patentee before: BEIJING INCREASE PHARMACEUTICAL RESEARCH INSTITUTE Co.,Ltd. Address after: 100088 Beijing city Xicheng District, New Street No. 2 Tiancheng Technology building block B room 3003 Patentee after: BEIJING INCREASE PHARMACEUTICAL RESEARCH INSTITUTE Co.,Ltd. Address before: 100088 Beijing city Xicheng District, New Street No. 2 Tiancheng Technology building block B room 3003 Patentee before: BEIJING INCREASE PHARMACEUTICAL TECHNOLOGY Co.,Ltd. |
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