CN101564487A - Jiehong medicine for injuries from falls and preparation method thereof - Google Patents
Jiehong medicine for injuries from falls and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a jiehong medicine for injuries from falls and a preparation method thereof, belonging to the technical field of traditional Chinese medicine preparation. The medicine preparation is a cataplasm which is prepared by 39 to 49 portions of safflower, 39 to 49 portions of catechu, 39 to 49 portions of angelica longicaudata, 17 to 27 portions of alum, 39 to 49 portions of sappan wood, 39 to 49 portions of aloe, 39 to 49 portions of frankincense, 39 to 49 portions of benzoin, 39 to 49 portions of myrrh and 39 to 49 portions of blood of dragon, concentrated solution of alcohol extract and matrix materials which are acceptable in pharmacy, and the above portions are weight portions. The preparation method comprises the following steps of: (1) preparation of the concentrated solution of alcohol extract; (2) preparation of matrix materials; and (3) preparation of the cataplasm. The medicine has the advantages of little stimulation to the skin, fast drug absorption and more convenient use, and can be used for curing symptoms of injuries from fall, damage of bones and muscles, swelling and pain of accumulated stasis and the like.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, more particularly, it relate to a kind of be used for the treatment of get injured by a fall, the Jiehong medicine for injuries from falls of diseases such as bones and muscles injury, long-pending swelling due to stasis, the invention still further relates to above-mentioned medicaments preparation method.
Background technology
Soft tissue injury is commonly encountered diseases, a frequently-occurring disease clinically, and worldwide, its sickness rate is only second to flu.Particularly be engaged in amusement, sports, or blue-collar philtrum, seldom do not suffering soft tissue injury.Soft tissue injury is meant that various causative factors of injury act on body and cause the disease of a series of pathological changes of soft tissue, and its pathological change is a principal character with local acute inflammation and reparation.Clinical local swelling, pain, dysfunction, livid purple stasis of blood class etc. of mainly showing as.Be divided into two kinds of acute injury (acute trauma) and chronic injuries (chronic trauma), and chronic injury is come by the acute injury transformation often, so acute soft tissue need obtain in time, effectively treatment.Modern medicine has the main Therapeutic Method of acute soft tissue injury: wrapping, partial closure, physical therapy etc., and these method curative effects are not good enough, and rehabilitation duration is longer.The medicine for external use of treatment acute soft tissue injury based on apply ointment or plaster, ointment, plaster, medicine loose, these medicines are again mainly based on conventional dosage forms, exist dosage form to fall behind and use inconvenience, positions such as trunk are difficult for wrapping up deficiencies such as the medicated clothing of firmly, easily making dirty, waste medicine, hindered further and promoted the use, also seek and treat acute soft tissue injury with medicinal herb spray, but its complicated process of preparation, reasons such as cost costliness have hindered further popularization.
Chinese medicine " exhausts red traumatic injury ", and the side mainly is made up of Sanguis Draxonis, Flos Carthami, Olibanum, Myrrha, Aloe, Radix Angelicae Sinensis, catechu, Lignum Sappan etc., generally use, be used to get injured by a fall bones and muscles injury with tincture, diseases such as long-pending swelling due to stasis, treatment has remarkable advantages and unique curative effect to soft tissue injury.But also there are two big subject matters at present in it: the one, and preparation process is backward relatively, and using dosage once is bigger, and local irritation is arranged, and has reduced patient's compliance, and quality standard is perfect inadequately, has limited its further developing in market; The 2nd, exhaust red traumatic injury tincture when patient uses, put the affected part on the skin after must soaking medicinal liquid with Cotton Gossypii, and to attach affected part and to make lasting soak behind the gauze infiltration medicinal liquid, again because the solvent volatility of tincture is strong, easily dry, in order to keep moistening, patient must add medicinal liquid at any time, equally also reduce patient's compliance, restricted its clinical practice.Having become this sick problem demanding prompt solution of treatment so study the modern preparation of external evident in efficacy, lasting, easy to use, also is an important topic of modernization of cmm.
Summary of the invention
The technical problem to be solved in the present invention is the above-mentioned deficiency at prior art, provides diseases such as a kind of more effectively treatment is got injured by a fall, bones and muscles injury, long-pending swelling due to stasis, the Jiehong medicine for injuries from falls little to skin irritation, that drug absorption fast, use is convenient.
Another technical problem that the present invention will solve provides a kind of preparation method of above-mentioned novel Jiehong medicine for injuries from falls.
Last technical scheme of the present invention is only such: a kind of Jiehong medicine for injuries from falls, be the cataplasma of being made by the ethanol extraction concentrated solution and the receptible host material of pharmaceutics of 39～49 parts on Flos Carthami, 39～49 parts in catechu, 39～49 parts of Radix Angelicae Sinensis, 17～27 parts of Alumens, 39～49 parts of Lignum Sappans, 39～49 parts of Aloes, 39～49 parts of Olibanums, 39～49 parts of Benzoinumes, 39～49 parts of Myrrhas, 39～49 parts of Sanguis Draxonis, above-mentioned deal is a weight portion.
Further, a kind of Jiehong medicine for injuries from falls of the present invention, its preferred plan is the cataplasma of being made by the ethanol extraction concentrated solution of 44 parts on Flos Carthami, 44 parts in catechu, 44 parts of Radix Angelicae Sinensis, 22 parts of Alumens, 44 parts of Lignum Sappans, 44 parts of Aloes, 44 parts of Olibanums, 44 parts of Benzoinumes, 44 parts of Myrrhas, 44 parts of Sanguis Draxonis and the receptible host material of pharmaceutics, and above-mentioned deal is a weight portion.
In above-mentioned a kind of Jiehong medicine for injuries from falls, described ethanol extraction concentrated solution is that extracting solution is concentrated into 25～35% of medical material weight; The weight ratio of described ethanol extraction concentrated solution and host material is 1: 2.0～5.0.
In above-mentioned a kind of Jiehong medicine for injuries from falls, described host material is to be selected from sodium polyacrylate, carbopol, hypromellose, polyvinylpyrrolidone, gelatin, Kaolin, silica gel, dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, 1, the wherein two or more at least mixture of 2-propylene glycol, tartaric acid, tween, distilled water, glycerol, azone.The preferred following material of described host material mixes by weight proportion, 0.01～1 part of 1～5 part of sodium polyacrylate, 1～5 part of carbopol, 1～10 part of Kaolin, 1～10 part in silica gel, 0.01～0.1 part of dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, 1,0.1～1 part of 2-propylene glycol, 0.01～0.1 part in tartaric acid, 10～50 parts of distilled water, 1～10 part of glycerol, 0.1～2 part of azone.
In above-mentioned a kind of Jiehong medicine for injuries from falls, also be added with the unguentum usual auxiliaries of concentrated solution weight 0.1～1% in the described ethanol extraction concentrated solution, described unguentum usual auxiliaries is meant at least a in menthol, Mentholum, Borneolum Syntheticum, azone, eucalyptus oil, Oleum Ricini, the methyl salicylate, with the flexibility, the tolerance to cold that improve medicament or play the Percutaneous absorption enhancer effect.
Back of the present invention one technical scheme is such: a kind of preparation method of Jiehong medicine for injuries from falls, comprise the preparation of (1) ethanol extraction concentrated solution, (2) preparation of the preparation of host material and (3) cataplasma, wherein the preparation method of (1) ethanol extraction concentrated solution is to get Flos Carthami, Lignum Sappan, Radix Angelicae Sinensis to be ground into coarse powder, adopting percolation, make solvent with 60～80% ethanol, is slowly percolation of 1～3ml/min by percolation speed, the ethanol that adds 5 times of amounts of medical material weight is altogether collected percolate; All the other catechu, Alumen, Aloe, Olibanum, Benzoinum, Myrrha, Sanguis Draxonis seven flavors are ground into coarse powder, with 60～80% alcohol dipping of above-mentioned percolate and 3 times of amounts of medical material 30 days, filter, filtrate decompression is concentrated into 30～40% the concentrated solution that weight is medical material weight; (2) preparation method of host material is that dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, glycerol and Kaolin is evenly mixed, adds sodium polyacrylate, fully grinds well; Tartaric acid is dissolved in the part distilled water, and gradation joins in the said mixture, stirs; The carbopol adding distil water is dissolved into clear solution, adds again in the said mixture, stir; Add azone, 1 at last, the 2-propylene glycol stirs promptly; (3) preparation method of cataplasma is to extract concentrated solution and the host material mixed by 1: 2.0～5.0, to stir 10～30 minutes, and coating covers upper protective film, section, and packing is promptly.
In the preparation method of above-mentioned a kind of Jiehong medicine for injuries from falls, described ethanol extraction concentrated solution also can prepare as follows: get Flos Carthami, Lignum Sappan, Radix Angelicae Sinensis and be ground into coarse powder, adopt percolation, make solvent with 60～80% ethanol, by percolation speed is slowly percolation of 1～3ml/min, the ethanol that adds 5 times of amounts of medical material weight is altogether collected percolate; All the other catechu, Alumen, Aloe, Olibanum, Benzoinum, Myrrha, Sanguis Draxonis seven flavors are ground into coarse powder, add twice of ultrasonic Treatment of 60～80% ethanol that 3 medical materials are doubly measured, two hours for the first time, one hour for the second time, filter, filtrate and above-mentioned percolate merge and be evaporated to 30～40% the concentrated solution that weight is medical material weight, or add the unguentum usual auxiliaries and stir; Can under the situation that guarantees extraction effect, improve extraction efficiency greatly.
The present invention compared with prior art has following advantage:
(1) cataplasma of the present invention adopts water-soluble base and water solublity, fat-soluble medicine intermiscibility good, and the drug loading of host material is big, is fit to very that Chinese medicine is formed minute more, the medication characteristics of heavy dose.
(2) water content is higher in the cataplasma of the present invention, and the keratodermatitis cell hydration is expanded, and more helps drug transdermal and absorbs.
(3) cataplasma breathability of the present invention is poor, to skin vigorous property, the equal tool of moisture retention obviously be better than traditional rubber-emplastrum, and use comfortable, little to skin irritation, can take off advantages such as paste not having pain repeatedly.
The specific embodiment
Below in conjunction with specific embodiment the present invention is described in further detail, but does not constitute any limitation of the invention.
Embodiment 1
One of preparation of ethanol extraction concentrated solution
Component: Flos Carthami 390g, catechu 390g, Radix Angelicae Sinensis 390g, Alumen 170g, Lignum Sappan 390g, Aloe 390g, Olibanum 390g, Benzoinum 390g, Myrrha 390g, Sanguis Draxonis 390g
Preparation method: getting Flos Carthami, Lignum Sappan, Radix Angelicae Sinensis and be ground into coarse powder, adopt percolation, make solvent with 60% ethanol, is slowly percolation of 1ml/min by percolation speed, adds the ethanol of 5 times of amounts of medical material weight altogether, the collection percolate; All the other catechu, Alumen, Aloe, Olibanum, Benzoinum, Myrrha, Sanguis Draxonis seven flavors are ground into coarse powder, and with 60% alcohol dipping of above-mentioned percolate and 3 times of amounts of medical material 30 days, filtration, it is 30% of medical material weight that filtrate decompression is concentrated into weight, about 1100g.
Embodiment 2
Two of the preparation of ethanol extraction concentrated solution
Component: Flos Carthami 440g, catechu 440g, Radix Angelicae Sinensis 440g, Alumen 220g, Lignum Sappan 440g, Aloe 440g, Olibanum 440g, Benzoinum 440g, Myrrha 440g, Sanguis Draxonis 440g
Preparation method: getting Flos Carthami, Lignum Sappan, Radix Angelicae Sinensis and be ground into coarse powder, adopt percolation, make solvent with 70% ethanol, is slowly percolation of 2ml/min by percolation speed, adds the ethanol of 5 times of amounts of medical material weight altogether, the collection percolate; All the other catechu, Alumen, Aloe, Olibanum, Benzoinum, Myrrha, Sanguis Draxonis seven flavors are ground into coarse powder, with 70% alcohol dipping of above-mentioned percolate and 3 times of amounts of medical material 30 days, filter, it is 35% of medical material weight that filtrate decompression is concentrated into weight, about 1460g adds the 12.5g eucalyptus oil then and mixes.
Embodiment 3
Three of the preparation of ethanol extraction concentrated solution
Component: Flos Carthami 490g, catechu 490g, Radix Angelicae Sinensis 490g, Alumen 270g, Lignum Sappan 490g, Aloe 490g, Olibanum 490g, Benzoinum 490g, Myrrha 490g, Sanguis Draxonis 490g
Preparation method: getting Flos Carthami, Lignum Sappan, Radix Angelicae Sinensis and be ground into coarse powder, adopt percolation, make solvent with 80% ethanol, is slowly percolation of 3ml/min by percolation speed, adds the ethanol of 5 times of amounts of medical material weight altogether, the collection percolate; All the other catechu, Alumen, Aloe, Olibanum, Benzoinum, Myrrha, Sanguis Draxonis seven flavors are ground into coarse powder, with 80% alcohol dipping of above-mentioned percolate and 3 times of amounts of medical material 30 days, filter, it is 40% of medical material weight that filtrate decompression is concentrated into weight, about 1870g adds menthol 2g then and mixes.
Embodiment 4
Four of the preparation of ethanol extraction concentrated solution
Component: Flos Carthami 440g, catechu 440g, Radix Angelicae Sinensis 440g, Alumen 220g, Lignum Sappan 440g, Aloe 440g, Olibanum 440g, Benzoinum 440g, Myrrha 440g, Sanguis Draxonis 440g
Preparation method: getting Flos Carthami, Lignum Sappan, Radix Angelicae Sinensis and be ground into coarse powder, adopt percolation, make solvent with 70% ethanol, is slowly percolation of 2ml/min by percolation speed, adds the ethanol of 5 times of amounts of weight altogether, the collection percolate; All the other catechu, Alumen, Aloe, Olibanum, Benzoinum, Myrrha, Sanguis Draxonis seven flavors are ground into coarse powder, 70% ethanol that adds medical material 3 amounts, with twice of ultrasonic Treatment, two hours for the first time, one hour for the second time, filter, be 35% of medical material weight with being evaporated to weight after filtrate and the percolate merging, about 1360g adds menthol 2g then and mixes.
Embodiment 5
One of medicaments preparation
The extract 3.5g that extracting solution concentrated solution: embodiment 1 is prepared.
Host material: sodium polyacrylate (NP-700) 0.9g, Kaolin 4.5g, ethylenediaminetetraacetic acid 0.15g, dihydroxyaluminum aminoacetate 0.03g, 1,2-propylene glycol 0.3g, tartaric acid 0.03g, glycerol 4.5g, azone 0.6g, distilled water 8g.
The host material preparation: dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, glycerol and Kaolin is evenly mixed, add sodium polyacrylate, fully grind well; Tartaric acid is dissolved in the part distilled water, joins at twice in the said mixture, stir; Add azone, 1 at last, the 2-propylene glycol stirs standby.
Medicaments preparation: extract is added in the preparation host material, and stirring grinds well, and this mixture stand is applied on the non-woven fabrics, and horizontal positioned covers upper protective film, and section packs room temperature and places, and gets final product.
Usage and consumption: be affixed on the affected part, paste every day one.
Embodiment 6
Two of medicaments preparation
The extract 4.4g that extracting solution concentrated solution: embodiment 2 is prepared.
Host material: sodium polyacrylate (NP-700) 0.6g, Kaolin 3g, ethylenediaminetetraacetic acid 0.1g, dihydroxyaluminum aminoacetate 0.025g, 1,2-propylene glycol 0.2g, tartaric acid 0.025g, glycerol 3.5g, azone 0.45g, distilled water 6.5g.
The host material preparation: dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, glycerol and Kaolin is evenly mixed, add sodium polyacrylate, fully grind well; Tartaric acid is dissolved in the part distilled water, joins at twice in the said mixture, stir; Add azone, 1 at last, the 2-propylene glycol stirs standby.
Medicaments preparation: extract is added in the preparation host material, and stirring grinds well, and this mixture stand is applied on the non-woven fabrics, and horizontal positioned covers upper protective film, and section packs room temperature and places, and gets final product.
Usage and consumption: be affixed on the affected part, paste every day one.
Embodiment 7
Three of medicaments preparation
The extract 5.7g that extracting solution concentrated solution: embodiment 3 is prepared.
Host material: sodium polyacrylate (NP-700) 0.6g, carbopol (
Ultrez21) 0.3g, Kaolin 4g, ethylenediaminetetraacetic acid 0.12g, dihydroxyaluminum aminoacetate 0.03g, 1,2-propylene glycol 0.25g, tartaric acid 0.02g, glycerol 4g, azone 0.5g, distilled water 6g.
The host material preparation: dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, glycerol and Kaolin is evenly mixed, add sodium polyacrylate, fully grind well; Tartaric acid is dissolved in the part distilled water, joins at twice in the said mixture, stir; The carbopol adding distil water is dissolved into clear solution, adds in the said mixture, stir; Add azone, 1 at last, the 2-propylene glycol stirs standby.
Medicaments preparation: the extracting solution concentrated solution is added in the preparation host material, and stirring grinds well, and this mixture stand is applied on the non-woven fabrics, and horizontal positioned covers upper protective film, and section packs room temperature and places, and gets final product.
Usage and consumption: be affixed on the affected part, paste every day one.
Embodiment 8
Four of medicaments preparation
The extract 4.4g that extracting solution concentrated solution: embodiment 4 is prepared.
Host material: sodium polyacrylate (NP-700) 0.6g, carbopol (
980NF) 0.2g, Kaolin 3.5g, ethylenediaminetetraacetic acid 0.15g, dihydroxyaluminum aminoacetate 0.03g, 1,2-propylene glycol 0.5g, tartaric acid 0.02g, glycerol 3.5g, azone 0.4g, distilled water 7g.
The host material preparation: dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, glycerol and Kaolin is evenly mixed, add sodium polyacrylate, fully grind well; Tartaric acid is dissolved in the part distilled water, joins at twice in the said mixture, stir; The carbopol adding distil water is dissolved into clear solution, adds in the said mixture, stir; Add azone, 1 at last, the 2-propylene glycol stirs standby.
Medicaments preparation: the extracting solution concentrated solution is added in the preparation host material, and stirring grinds well, and this mixture stand is applied on the non-woven fabrics, and horizontal positioned covers upper protective film, and section packs room temperature and places, and gets final product.
Usage and consumption: be affixed on the affected part, paste every day one.
Claims (10)
1. Jiehong medicine for injuries from falls, it is characterized in that it being the cataplasma of being made by the ethanol extraction concentrated solution and the receptible host material of pharmaceutics of 39～49 parts on Flos Carthami, 39～49 parts in catechu, 39～49 parts of Radix Angelicae Sinensis, 17～27 parts of Alumens, 39～49 parts of Lignum Sappans, 39～49 parts of Aloes, 39～49 parts of Olibanums, 39～49 parts of Benzoinumes, 39～49 parts of Myrrhas, 39～49 parts of Sanguis Draxonis, above-mentioned deal is a weight portion.
2. a kind of Jiehong medicine for injuries from falls according to claim 1, it is characterized in that it being the cataplasma of being made by the ethanol extraction concentrated solution and the receptible host material of pharmaceutics of 44 parts on Flos Carthami, 44 parts in catechu, 44 parts of Radix Angelicae Sinensis, 22 parts of Alumens, 44 parts of Lignum Sappans, 44 parts of Aloes, 44 parts of Olibanums, 44 parts of Benzoinumes, 44 parts of Myrrhas, 44 parts of Sanguis Draxonis, above-mentioned deal is a weight portion.
3. a kind of Jiehong medicine for injuries from falls according to claim 1 is characterized in that described ethanol extraction concentrated solution is that extracting solution is concentrated into 30～40% of medical material weight.
4. a kind of Jiehong medicine for injuries from falls according to claim 3, the weight ratio that it is characterized in that described ethanol extraction concentrated solution and host material is 1: 2.0～5.0.
5. according to claim 1 or 2 or 4 described a kind of Jiehong medicine for injuries from falls, it is characterized in that described host material is to be selected from sodium polyacrylate, carbopol, hypromellose, polyvinylpyrrolidone, gelatin, Kaolin, silica gel, dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, 1, the wherein two or more at least mixture of 2-propylene glycol, tartaric acid, tween, distilled water, glycerol, azone.
6. a kind of Jiehong medicine for injuries from falls according to claim 5, it is characterized in that described host material is to be mixed by weight proportion by following material, 0.01～1 part of 1～5 part of sodium polyacrylate, 1～5 part of carbopol, 1～10 part of Kaolin, 1～10 part in silica gel, 0.01～0.1 part of dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, 1,0.1～1 part of 2-propylene glycol, 0.01～0.1 part in tartaric acid, 10～50 parts of distilled water, 1～10 part of glycerol, 0.1～2 part of azone.
7. according to claim 1 or 2 or 3 described a kind of Jiehong medicine for injuries from falls, it is characterized in that also being added with in the described ethanol extraction concentrated solution unguentum usual auxiliaries of concentrated solution weight 0.1～1%, described unguentum usual auxiliaries is meant at least a in menthol, Mentholum, Borneolum Syntheticum, azone, eucalyptus oil, Oleum Ricini, the methyl salicylate; Described host material is to be mixed by weight proportion by following material, 0.01～1 part of 1～5 part of sodium polyacrylate, 1～5 part of carbopol, 1～10 part of Kaolin, 1～10 part in silica gel, 0.01～0.1 part of dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, 1,0.1～1 part of 2-propylene glycol, 0.01～0.1 part in tartaric acid, 10～50 parts of distilled water, 1～10 part of glycerol, 0.1～2 part of azone.
8. the preparation method of the described a kind of Jiehong medicine for injuries from falls of claim 6, it is characterized in that comprising the preparation of (1) ethanol extraction concentrated solution, (2) preparation of the preparation of host material and (3) cataplasma, wherein the preparation method of (1) ethanol extraction concentrated solution is to get Flos Carthami, Lignum Sappan, Radix Angelicae Sinensis to be ground into coarse powder, adopting percolation, make solvent with 60～80% ethanol, is slowly percolation of 1～3ml/min by percolation speed, the ethanol that adds 5 times of amounts of medical material weight is altogether collected percolate; All the other catechu, Alumen, Aloe, Olibanum, Benzoinum, Myrrha, Sanguis Draxonis seven flavors are ground into coarse powder, with 60～80% alcohol dipping of above-mentioned percolate and 3 times of amounts of medical material 30 days, filter, filtrate decompression is concentrated into 30～40% the concentrated solution that weight is medical material weight; (2) preparation method of host material is that dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, glycerol and Kaolin is evenly mixed, adds sodium polyacrylate, fully grinds well; Tartaric acid is dissolved in the part distilled water, and gradation joins in the said mixture, stirs; The carbopol adding distil water is dissolved into clear solution, adds again in the said mixture, stir; Add azone, 1 at last, the 2-propylene glycol stirs promptly; (3) preparation method of cataplasma is to extract concentrated solution and the host material mixed by 1: 2.0～5.0, to stir 10～30 minutes, and coating covers upper protective film, section, and packing is promptly.
9. the preparation method of the described a kind of Jiehong medicine for injuries from falls of claim 7, it is characterized in that comprising the preparation of (1) ethanol extraction concentrated solution, (2) preparation of the preparation of host material and (3) cataplasma, wherein the preparation method of (1) ethanol extraction concentrated solution is to get Flos Carthami, Lignum Sappan, Radix Angelicae Sinensis to be ground into coarse powder, adopting percolation, make solvent with 60～80% ethanol, is slowly percolation of 1～3ml/min by percolation speed, the ethanol that adds 5 times of amounts of medical material weight is altogether collected percolate; All the other catechu, Alumen, Aloe, Olibanum, Benzoinum, Myrrha, Sanguis Draxonis seven flavors are ground into coarse powder, with 60～80% alcohol dipping of above-mentioned percolate and 3 times of amounts of medical material 30 days, filter, filtrate decompression is concentrated into 30～40% the concentrated solution that weight is medical material weight, adds the unguentum usual auxiliaries at last and stirs; (2) preparation method of host material is that dihydroxyaluminum aminoacetate, ethylenediaminetetraacetic acid, glycerol and Kaolin is evenly mixed, adds sodium polyacrylate, fully grinds well; Tartaric acid is dissolved in the part distilled water, and gradation joins in the said mixture, stirs; The carbopol adding distil water is dissolved into clear solution, adds again in the said mixture, stir; Add azone, 1 at last, the 2-propylene glycol stirs promptly; (3) preparation method of cataplasma is to extract concentrated solution and the host material mixed by 1: 2.0～5.0, to stir 10～30 minutes, and coating covers upper protective film, section, and packing is promptly.
10. according to Claim 8 or the preparation method of 9 described a kind of Jiehong medicine for injuries from falls, the preparation method that it is characterized in that described ethanol extraction concentrated solution is to get Flos Carthami, Lignum Sappan, Radix Angelicae Sinensis to be ground into coarse powder, adopt percolation, make solvent with 60～80% ethanol, by percolation speed is slowly percolation of 1～3ml/min, the ethanol that adds 5 times of amounts of medical material is altogether collected percolate; All the other catechu, Alumen, Aloe, Olibanum, Benzoinum, Myrrha, Sanguis Draxonis seven flavors are ground into coarse powder, add twice of ultrasonic Treatment of 60～80% ethanol of 3 times of amounts of medical material, two hours for the first time, one hour for the second time, filter, filtrate and above-mentioned percolate merge and be evaporated to 30～40% the concentrated solution that weight is medical material weight, or add the unguentum usual auxiliaries and stir.
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| CNA2009100399504A CN101564487A (en) | 2009-06-03 | 2009-06-03 | Jiehong medicine for injuries from falls and preparation method thereof |
| CN200910225965XA CN101703667B (en) | 2009-06-03 | 2009-11-21 | Brown red medicament for treating traumatic injuries and preparation method thereof |
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| CNA2009100399504A CN101564487A (en) | 2009-06-03 | 2009-06-03 | Jiehong medicine for injuries from falls and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641371A (en) * | 2012-05-08 | 2012-08-22 | 辽宁中医药大学附属医院 | Cataplasma for treating body surface infectious diseases |
| CN105935401A (en) * | 2015-03-02 | 2016-09-14 | 重庆市中药研究院 | Gel paste for treating injured muscles and bones and preparation method thereof |
| CN107714835A (en) * | 2017-10-20 | 2018-02-23 | 山东中医药大学 | A kind of Daphne giraldii Nitsche total coumarin cataplasm for improving daphnetin bioavilability |
| CN108704162A (en) * | 2018-08-08 | 2018-10-26 | 中国科学院长春应用化学研究所 | A kind of water suction dressing and preparation method thereof |
| CN109331159A (en) * | 2018-11-15 | 2019-02-15 | 谈宗华 | A kind of gel emplastrum and preparation method thereof for treating dysmenorrhea |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641371A (en) * | 2012-05-08 | 2012-08-22 | 辽宁中医药大学附属医院 | Cataplasma for treating body surface infectious diseases |
| CN105935401A (en) * | 2015-03-02 | 2016-09-14 | 重庆市中药研究院 | Gel paste for treating injured muscles and bones and preparation method thereof |
| CN107714835A (en) * | 2017-10-20 | 2018-02-23 | 山东中医药大学 | A kind of Daphne giraldii Nitsche total coumarin cataplasm for improving daphnetin bioavilability |
| CN107714835B (en) * | 2017-10-20 | 2020-09-04 | 山东中医药大学 | Daphne giraldii Nitsche total coumarin cataplasm for improving bioavailability of Daphne giraldii Nitsche A |
| CN108704162A (en) * | 2018-08-08 | 2018-10-26 | 中国科学院长春应用化学研究所 | A kind of water suction dressing and preparation method thereof |
| CN109331159A (en) * | 2018-11-15 | 2019-02-15 | 谈宗华 | A kind of gel emplastrum and preparation method thereof for treating dysmenorrhea |
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