CN109223860A - A kind of compound five-element grass spray - Google Patents

A kind of compound five-element grass spray Download PDF

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Publication number
CN109223860A
CN109223860A CN201811177565.1A CN201811177565A CN109223860A CN 109223860 A CN109223860 A CN 109223860A CN 201811177565 A CN201811177565 A CN 201811177565A CN 109223860 A CN109223860 A CN 109223860A
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China
Prior art keywords
compound
parts
mentholum
medical fluid
dandelion
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Pending
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CN201811177565.1A
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Chinese (zh)
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刘振普
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Individual
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Individual
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Priority to CN201811177565.1A priority Critical patent/CN109223860A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention discloses a kind of compound five-element grass sprays, consisting of 10~30 parts of purslane, 10~20 parts of dandelion, 0.1~10 part of Mentholum.The present invention is prepared using water extraction and alcohol precipitation method, and step includes: to decoct after soaking in water purslane and dandelion, filters out medical fluid, then medical fluid and dehydrated alcohol are mixed, Mentholum is added after standing, taking upper layer clear liquid is external-use tincture.The present invention have it is at low cost, have no toxic side effect, drug safety, feature easy to use can rapid healing multiple dermatosis.

Description

A kind of compound five-element grass spray
Technical field
Medicine more particularly to a kind of compound five-element grass spray are applied outside the present invention relates to a kind of.
Background technique
Skin disease is a kind of clinical relatively conventional disease, treats dermatosis treating medicine currently on the market and contains hormone mostly, stops It is only recurred immediately after use, long-time service can cause a variety of side effects.It is for skin disease main coating and oral medicine in addition Main, traditional outer coating has a single function, and therapeutic effect is bad, and cost performance is also undesirable.
Water extraction and alcohol precipitation method is commonly used for the refining methd of traditional Chinese medicine extraction purifying, and medicinal material is extracted by decocting, wherein biology The aqueous soluble active constituents such as alkali, acylate, amino acids are extracted, and ethyl alcohol is added, effective component is made to be dissolved in ethyl alcohol In, other impurities are precipitable to get off.
Ingredient is purslane in patent CN1927236A entitled " a kind of drug for treating shingles zoster ", and treatment patient is total 50, but have recurrence rate, and treat and have a single function.
Summary of the invention
The object of the present invention is to provide a kind of compound five-element grass spray, solve outer coating have a single function, therapeutic effect and property Valence is than undesirable problem.
A kind of compound five-element grass spray, which is characterized in that the component including following parts by weight: 1~30 part of purslane, Pu 5~20 parts of public English, 0.1~10 part of Mentholum.
Preferably, the constituent parts by weight are as follows: 10~20 parts of purslane, 10~15 parts of dandelion, Mentholum 1 ~5 parts.
Compound five-element's grass spray production method of the invention: 0.5~1.5 is decocted after purslane and dandelion are soaked in water Hour, it filters out medical fluid and again mixes medical fluid and dehydrated alcohol, Mentholum is added after standing 24~36 hours, takes the clear and bright liquid in upper layer Body is external-use tincture.
Preferably, the soaking time is 1 hour.
Preferably, the decocting time is 1.5 hours.
Preferably, the weight of the dehydrated alcohol is 1.5 times of medical fluid.
Preferably, the time of repose is 48 hours.
Compound five-element's grass spray suggested use and dosage of the invention: skin affected part, each 5ml, one day 1-2 are applied directly to It is secondary, ten days as a treatment course.
The taboo of spray of the present invention: 1, this product allergy sufferers are disabled;2, infants and children is used with caution;3, this product is served only for outer It applies, forbids taking orally.
Pharmacological action: purslane, cold in nature, acid sweet in flavor, clearing heat and detoxicating, scattered blood detumescence;Dandelion, bitter sweet are trembled with fear, heat-clearing solution Poison, dispersing swelling and dissipating binds;Mentholum, dispelling wind, heat-clearing, antipruritic, anti-inflammatory analgetic.
Compared with prior art, advantageous effects of the invention: compound five-element's grass spray of the invention uses Chinese medicine It proposes have at low cost, has no toxic side effect, drug safety, feature easy to use can rapid healing epifolliculitis, band-like The multiple dermatosis such as bleb, acne, eczema, serious case of furuncle, hemorrhoid, prickly heat.
Specific embodiment
The preferred embodiments of the present invention will be described in detail below, so that advantages and features of the invention can be easier It is readily appreciated by one skilled in the art, to make apparent specific boundary's point to protection scope of the present invention.
Embodiment 1:
20 portions of purslanes and 15 portions of dandelions are soaked in water one hour, then heating decocts 1.5 hours, medical fluid is filtered out, 1.5 times of medical fluid weight of dehydrated alcohol is added inside medical fluid, mixing stands 48 hours, adds 2 parts of Mentholums, take upper layer Clear liquid is up to compound five-element grass spray of the present invention.Treatment results such as table 1 about shingles zoster.
Table 1
Number of cases Recovery from illness It is efficient
Purslane 50 7 days 95%
Spray of the invention 70 10 days 100%
Treatment results: this medicine is used through clinical 100 dermatosis patients, effect highly significant, cures within 10~20 days, has Efficiency is up to absolutely.
The treatment case of drug of the present invention:
Case 1, Mr. Wang, 55 years old, because suffer from shingles zoster over 5 days I go to a doctor.There is burning heat sensation nerve in patient back Bitterly, there is flush spot, papule miliary to soybean-sized then occur, quickly become blister, tonic vesicle wall is shinny, and blister liquid is clear Clear periphery is around with blush.Compound five-element's grass spray external application through being developed with me, three days take effect, and fully recover within 10 days.
Case 2 is permitted so-and-so, and 45 years old, certain TV station of county worker.Because suffering from epifolliculitis for many years, it is invalid to seek medical advice everywhere, through with I The compound five-element's grass spray developed takes effect for external application two days, cures within 15 days.
Case 3, Liu, it is 65 years old, continuous to use through being taken effect within external application 10 days with compound five-element's grass preparation because suffering from thorn monkey 1 year It cures within 20 days.
Case 4, Mr. Li, 63 years old, because suffer from shingles zoster over 5 days I go to a doctor.Compound five-element's grass through being developed with me Spray external application, three days take effect, and fully recover within 15 days.
Case 5, Liu, 43 years old, serious because suffering from eczema many years toe, it is invalid to seek medical advice everywhere, through being answered with what I was developed Square five-element's grass spray, external application two days take effect, and cure within 20 days.
Embodiment described above is only that preferred embodiment of the invention is described, not to the scope of the present invention into Row limits, and without departing from the spirit of the design of the present invention, those of ordinary skill in the art do technical solution of the present invention Various changes and improvements out should all be fallen into the protection scope that claims of the present invention determines.

Claims (7)

1. a kind of compound five-element grass spray, which is characterized in that the component including following parts by weight: 1~30 part of purslane, dandelion 5~20 parts, 0.1~10 part of Mentholum.
2. compound five-element grass spray according to claim 1, which is characterized in that the component including following parts by weight: dent 10~20 parts of amaranth, 10~15 parts of dandelion, 1~5 part of Mentholum.
3. a kind of preparation method of compound five-element grass spray, which comprises the steps of: add purslane and dandelion Water impregnates, and decocts 0.5~1.5 hour after so that water was not had medicinal material, filters out medical fluid, then medical fluid and dehydrated alcohol are mixed, stands 24 Mentholum is added after~36 hours, taking upper layer clear liquid is external-use tincture.
4. the preparation method of compound five-element grass spray according to claim 3, which is characterized in that the soaking time is 1 Hour.
5. the preparation method of compound five-element grass spray according to claim 3, which is characterized in that the decocting time is 1.5 hour.
6. the preparation method of compound five-element grass spray according to claim 3, which is characterized in that the weight of the dehydrated alcohol Amount is 1.5 times of medical fluid.
7. the preparation method of compound five-element grass spray according to claim 3, which is characterized in that the time of repose is 48 Hour.
CN201811177565.1A 2018-10-10 2018-10-10 A kind of compound five-element grass spray Pending CN109223860A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811177565.1A CN109223860A (en) 2018-10-10 2018-10-10 A kind of compound five-element grass spray

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811177565.1A CN109223860A (en) 2018-10-10 2018-10-10 A kind of compound five-element grass spray

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110403979A (en) * 2019-09-03 2019-11-05 陕西伟荣科创实业有限公司 A kind of ointment of the treatment acne containing mongollian thyme herb volatile oil
CN113577196A (en) * 2021-08-19 2021-11-02 孔庆博 Medicament for various skin diseases and preparation method and application thereof
CN114404475A (en) * 2022-01-14 2022-04-29 曹和平 Traditional Chinese medicine formula for treating herpes zoster

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101450094A (en) * 2008-12-26 2009-06-10 杜晓生 Medicine for treating herpes zoster
CN104107251A (en) * 2014-08-06 2014-10-22 赵西迷 Medicinal liquor for treating skin diseases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101450094A (en) * 2008-12-26 2009-06-10 杜晓生 Medicine for treating herpes zoster
CN104107251A (en) * 2014-08-06 2014-10-22 赵西迷 Medicinal liquor for treating skin diseases

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
周德生 等: "《中医外治方全书(珍藏本)豪华精装版》", 31 October 2015, 湖南科学技术出版社 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110403979A (en) * 2019-09-03 2019-11-05 陕西伟荣科创实业有限公司 A kind of ointment of the treatment acne containing mongollian thyme herb volatile oil
CN113577196A (en) * 2021-08-19 2021-11-02 孔庆博 Medicament for various skin diseases and preparation method and application thereof
CN114404475A (en) * 2022-01-14 2022-04-29 曹和平 Traditional Chinese medicine formula for treating herpes zoster

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Application publication date: 20190118

RJ01 Rejection of invention patent application after publication