CN101450094A - Medicine for treating herpes zoster - Google Patents
Medicine for treating herpes zoster Download PDFInfo
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- CN101450094A CN101450094A CNA2008101366293A CN200810136629A CN101450094A CN 101450094 A CN101450094 A CN 101450094A CN A2008101366293 A CNA2008101366293 A CN A2008101366293A CN 200810136629 A CN200810136629 A CN 200810136629A CN 101450094 A CN101450094 A CN 101450094A
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- herpes zoster
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- scolopendra
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Abstract
The invention discloses a medicine for treating herpes zoster, which comprises the following components by weight parts: 3-10 of centipede, 5-15 of realgar, 8-30 of natural oindigo, 8-15 of dandelion, 5-20 of purslane, 5-15 of Renzhonghuang, 6-10 of purple gromwell root, 10-15 of green gram and vegetable oil. All the components are smashed and mixed. Clinic application and observation verifies that: treating herpes zoster by the medicine of the invention achieves the advantages of fast, short in relieve pain time which is less than half of that of the current medicine, no pigmentation mostly, low curing cost, no untoward reaction and no side effect.
Description
Technical field: the present invention relates to a kind of medicine for the treatment of herpes zoster.
Background technology: herpes zoster is a kind of acute herpetic dermatosis relevant with viral infection, be that varicella-zoster virus infects a kind of herpes and be the viral dermatosis of feature with the neuralgia of trooping to distribute along peripheral nerve cause, the traditional Chinese medical science claims " herpes zoster " this sick clinical manifestation often not to be true to type, the source property sent out skin lesion can appear, the companion has an intense pain, even severe complication such as hyperpyrexia encephalitis takes place; Herpes zoster was often sent out spring, autumn, and is common to be grown up, and the flushing speckle takes place earlier affected part, then the foxtail millet grain that occurs most one-tenth group variety collection on it is to the big papulovesicle of Semen phaseoli radiati, become vesicle, the transparent clarification of vesicle, tonic vesicle wall is shinny, there is blush in bleb week, muddy gradually later on, several groups of vesicles often are banded along a routine tegumentary nerve arranges, and generally is no more than the body surface center line, sometimes the offside at center line has the minority skin to examine, due to being got involved by the neural subbranch of crossing offside.Vesicle is dry after a few days, and erythema fugax or pigementation are left in incrustation behind the decrustation.Neuralgia is one of feature of primary disease, but also has neuralgia that erythra just took place after 4-5 days, thereby easily mistaken diagnosis.Antiviral drugs polyinosini commonly used clinically at present, acycloguanosine, acyclovir, aspirin adopts intravenously administrable or intramuscular injection, puts 0.5% neomycin ointment outward on the skin; Its treatment time is longer, and recovery from illness is slow, the side effect such as back pigmentation of healing.
Summary of the invention: the present invention will provide a kind of medicine for the treatment of herpes zoster, and the treatment recovery from illness is fast, the calm few side effects of non-pigment, and treatment time is short.
The medicine that the present invention treats herpes zoster comprises following parts by weight of component Scolopendra 3～10, Realgar 5～15, Indigo Naturalis 8～30, Herba Taraxaci 8～15, Herba Portulacae 5～20, Preparatum Glycyrrhizae 5～15, Radix Arnebiae (Radix Lithospermi) 6～10 and can make each component fully concoct moistening vegetable oil.
The present invention constitutes Scolopendra 5～7, Realgar 5～8, Indigo Naturalis 10～20, Herba Taraxaci 10～12, Herba Portulacae 10～15, Preparatum Glycyrrhizae 8～12, Radix Arnebiae (Radix Lithospermi) 6～10, Semen phaseoli radiati 10～15 and Camellia oil 50～100 by weight components.
The present invention preferably constitutes Scolopendra 5, Realgar 8, Indigo Naturalis 10, Herba Taraxaci 10, Herba Portulacae 15, Preparatum Glycyrrhizae 12, Radix Arnebiae (Radix Lithospermi) 8, Semen phaseoli radiati 10 and Camellia oil 80 by weight components and reconciles into.
The present invention treats the method for producing medicines of herpes zoster, with Chinese medicine composition medicine preparation method commonly used be with above-mentioned each component by the abundant mixed grinding powdered of proportioning, add vegetable oil then, reconcile into scattered paste shape, described vegetable oil is selected Camellia oil for use, vegetable oil or cotton oil etc., preferred Camellia oil.
Use the medicine external preparation (cream) of the treatment herpes zoster of proof the present invention preparation through clinical trial, have evident in efficacy, the herpes pain relief is fast, the course of treatment, existing medicine shortened half, pigmentation is few, and healing speed is fast, and safe and simple, clinical experiment is used, cure rate is up to 84.6%, and clinical total effective rate reaches 95%.
The present invention uses the part medical material, and pharmacological effect is as follows:
The main effect of Scolopendra: warm in nature, acrid in the mouth, separate sore, toxic.
The main effect of Realgar: parasite killing, separate the snakeworm poison, control scabies, Xin Wen is toxic.
The main effect of Indigo Naturalis: control aphtha of the mouth and tongue, apply pyretic toxicity carbuncle and insect-bite and sting etc., have antipyretic and antidote functions, no side effects.
The main effect of Semen phaseoli radiati: heat-clearing and toxic substances removing, inducing diuresis to remove edema, no side effects can be drunk as food
The main effect of Herba Taraxaci: heat-clearing and toxic substances removing, eliminating stagnation eliminating carbuncle, no side effects.
The main effect of Herba Portulacae: heat-clearing and toxic substances removing, external can be controlled erysipelas, scabies, no side effects.
The main effect of Preparatum Glycyrrhizae: clearing away heat-fire, Detoxication, no side effects.
The main effect of Radix Arnebiae (Radix Lithospermi): detoxifcation, removing heat from blood and blood can be controlled the fiber crops poison of diagnosing a disease, no side effects.
The present invention adds above-mentioned each component drug, and its pharmacological property is in harmonious proportion each other, and some Chinese medicines such as Scolopendra are arranged, Realgar has certain toxicity, and the Indigo Naturalis that adds, Semen phaseoli radiati, Herba Taraxaci, Herba Portulacae, Preparatum Glycyrrhizae and Radix Arnebiae (Radix Lithospermi) all have antipyretic and antidote functions, thereby reach neutralization blending effect, the present invention generally smears use with local external application, and dosage is little, can not produce toxic and side effects to human body; Untoward reaction and toxic and side effects do not appear after clinical patients case operating position shows, smears medicament of the present invention.
The specific embodiment: the inventor has carried out clinical observation to the effect of the banded herpes disease of Drug therapy of the present invention.
1, clinical data: picked at random 2000 to 2006 year clinic cases 40 examples, wherein male 25 examples, women 15 examples at 40-68 years old ages, are fallen ill in 33 examples of waist flank 5 examples of buccal portion, 2 examples of extremity; Be divided into treatment group and matched group at random; Wherein 22 examples are organized in treatment, matched group 18 examples.
2, clinical diagnosis standard, 40 examples all are diagnosed as herpes zoster all collection bunch vesicle group, and zonal distribution with tangible neuralgia characteristics, does not have other complication.
3, Therapeutic Method:
Inject identical with matched group with official ceremonial dress treatment group: oral and injecting drug use all adopts existing common drug to carry out, as the oral medicine acyclovir, and injection intramuscular injection polyinosinic-polytidylin acid etc.;
External: treatment group: with the medicine of the present invention of Camellia oil furnishing scattered paste shape, the part is outer to be applied to the affected part, and every day 2 times, state of an illness weight person smears number of times and increases to 3-6 time, and 7-10 days is a course of treatment.Matched group: with 0.5% neomycin ointment, use, be applied in the affected part, 2-3 courses of treatment Monday by its operation instruction.
4, criterion of therapeutical effect
Cure: deflorescence, clinical sign disappears, and pain thoroughly disappears.
Take a turn for the better: erythra drying, deflorescence are more than 50%, and clinical sign partly disappears, pain relief.
Invalid: erythra healing less than 30%, clinical sign pain is obvious.
5, therapeutic outcome
Adopt medicine of the present invention and treatment of control group to imitate and the results are shown in Table 1
Table 1 curative effect of medication of the present invention is (P＜0.01) relatively
| Group | The example number | Cure | Take a turn for the better | Invalid | Total effective rate % |
| The treatment group | 22 | 18 | 3 | 1 | 95.4 |
| Matched group | 18 | 13 | 3 | 2 | 88.9 |
Totally 22 routine cases in the treatment group, 18 examples of wherein fully recovering, 3 examples that take a turn for the better, invalid 1 example, cure rate 81.8% is cured 13 examples, 3 examples that take a turn for the better, invalid 2 examples, cure rate 72.2%, total effective rate 88.8% in total effective rate 95.4% matched group 18 examples.
Explanation is discussed: by adopting Drug therapy of the present invention and adopting matched group method treatment contrast, use the patient of Drug therapy of the present invention, pain was all obviously alleviated in 2-3 days, then pain complete obiteration in 4-6 days, blister disappeared in 7-10 days, and from the 18 routine cases of curing have 12 routine non-pigment calmnesses generally in 10 days the whole course of treatment, and 6 examples have a little pigmentation.
Adopt the patient of treatment of control group, pain relief in 4-5 days, pain disappeared in 7-14 days, and blister needs just to disappear more than 2 weeks, complete 2-3 weeks of the course of treatment; And ubiquity pigmentation more.
By showing that with treatment of control group contrast clinical observation the banded herpes pain relief of employing Drug therapy of the present invention is fast, curative effect is obvious, and shorten half the course of treatment, and can make some cases not stay pigmentation, avoids influencing the cosmetic result of exposure portion; Medication is smeared the time patient and any toxic and side effects do not occurred, is a kind of safety, the active drug of easy use.
The model case brief introduction: the patient, Lin, the man, 52 years old, the workman was because of old property of left midriff severe pain was gone to a doctor in mid-May, 2004.Have a medical check-up: T36.2 ℃ of BP130/90KPa, spirit is not good enough, and expression is painful, cardiopulmonary (), the abdomen average is soft, left midriff tenderness (+), no rebound tenderness and muscle tonus.Previously there is not " lithangiuria " medical history.Be diagnosed as " stomachache is waited to look into, lithangiuria "? give " Progesterone 40mg, intramuscular injection, norfloxacin 500ml, 654-210mg, quiet fat drop "; And continue to observe, do not see after 1 day to be clearly better that row abdominal part position clinostatism sheet is checked no abnormality seen, two kidneys, spleen is ultrasonic shows no obvious abnormalities.After 2 days, a plurality of herpess appear in the left side waist and belly, the clarification of bubble liquid, tonic vesicle wall, enclose with blush, normal skin is arranged between rash, and the cluster that has and not merging is zonal distribution, examine and be " herpes zoster ", give that routine and medicine external of the present invention are smeared, injection, oral medication, the dry incrustation of herpes after 7 days, non-pigment calmness.
Each composition weight is gram among following each embodiment, and embodiment 1: Scolopendra 7, Realgar 6, Indigo Naturalis 15, Herba Taraxaci 10, Herba Portulacae 12, Preparatum Glycyrrhizae 10, Radix Arnebiae (Radix Lithospermi) 8, vegetable oil 80.
Embodiment 2: Scolopendra 5, Realgar 8, Indigo Naturalis 10, Herba Taraxaci 10, Herba Portulacae 15, Preparatum Glycyrrhizae 12, Radix Arnebiae (Radix Lithospermi) 10, Semen phaseoli radiati 10, Camellia oil 100.
Preparation method is that above-mentioned each component drug is dried, and adds vegetable oil such as Camellia oil after the pulverizing again, and fully mediation can be standby.
Claims (3)
1, a kind of medicine for the treatment of herpes zoster comprises following parts by weight of component: Scolopendra 3～10, Realgar 5～15, Indigo Naturalis 8～30, Herba Taraxaci 8～15, Herba Portulacae 5～20, Preparatum Glycyrrhizae 5～15, Radix Arnebiae (Radix Lithospermi) 6～10 and can make each component fully concoct moistening vegetable oil.
2, according to the medicine of the described treatment herpes zoster of claim 1, it is characterized in that constituting: Scolopendra 5～7, Realgar 5～8, Indigo Naturalis 10～20, Herba Taraxaci 10～12, Herba Portulacae 10～15, Preparatum Glycyrrhizae 8～12, Radix Arnebiae (Radix Lithospermi) 6～10, Semen phaseoli radiati 10～15 and Camellia oil 50～100 by weight components.
3, according to the medicine of claim 1 or 2 described treatment herpes zoster, it is characterized in that constituting: Scolopendra 5, Realgar 8, Indigo Naturalis 10, Herba Taraxaci 10, Herba Portulacae 15, Preparatum Glycyrrhizae 12, Radix Arnebiae (Radix Lithospermi) 8, Semen phaseoli radiati 10 and Camellia oil 80 by weight components.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101366293A CN101450094B (en) | 2008-12-26 | 2008-12-26 | Medicine for treating herpes zoster |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101366293A CN101450094B (en) | 2008-12-26 | 2008-12-26 | Medicine for treating herpes zoster |
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| Publication Number | Publication Date |
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| CN101450094A true CN101450094A (en) | 2009-06-10 |
| CN101450094B CN101450094B (en) | 2011-01-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2008101366293A Expired - Fee Related CN101450094B (en) | 2008-12-26 | 2008-12-26 | Medicine for treating herpes zoster |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103070892A (en) * | 2013-01-10 | 2013-05-01 | 济南康众医药科技开发有限公司 | Application of freeze-dried purslane in preparing drug for treating herpes zoster |
| CN107714892A (en) * | 2017-10-27 | 2018-02-23 | 何保达 | A kind of external Chinese medicament for treating sore tinea scald and preparation method thereof |
| CN108514620A (en) * | 2018-07-12 | 2018-09-11 | 屈建平 | A kind of traditional Chinese medicine composition for herpes and preparation method thereof |
| CN109223860A (en) * | 2018-10-10 | 2019-01-18 | 刘振普 | A kind of compound five-element grass spray |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1357348A (en) * | 2000-12-08 | 2002-07-10 | 汤道荃 | Zoster treating liniment |
| CN1408378A (en) * | 2001-09-27 | 2003-04-09 | 汤仪 | Herpes zoster tincture |
| CN101185684B (en) * | 2007-12-11 | 2011-10-12 | 叶志群 | Externally-applied medicine for treating zoster |
-
2008
- 2008-12-26 CN CN2008101366293A patent/CN101450094B/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103070892A (en) * | 2013-01-10 | 2013-05-01 | 济南康众医药科技开发有限公司 | Application of freeze-dried purslane in preparing drug for treating herpes zoster |
| CN107714892A (en) * | 2017-10-27 | 2018-02-23 | 何保达 | A kind of external Chinese medicament for treating sore tinea scald and preparation method thereof |
| CN108514620A (en) * | 2018-07-12 | 2018-09-11 | 屈建平 | A kind of traditional Chinese medicine composition for herpes and preparation method thereof |
| CN109223860A (en) * | 2018-10-10 | 2019-01-18 | 刘振普 | A kind of compound five-element grass spray |
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| CN101450094B (en) | 2011-01-26 |
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