CN103263598B - Chinese medicine preparation for treating peripheral facial paralysis diseases - Google Patents

Chinese medicine preparation for treating peripheral facial paralysis diseases Download PDF

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CN103263598B
CN103263598B CN201310209507.3A CN201310209507A CN103263598B CN 103263598 B CN103263598 B CN 103263598B CN 201310209507 A CN201310209507 A CN 201310209507A CN 103263598 B CN103263598 B CN 103263598B
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chinese medicine
medicine preparation
preparation
facial
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CN103263598A (en
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张颖新
陈新华
纪青山
张炜煜
金艳芳
刘春�
陈春海
徐立光
丁庆刚
杜鹃
韩珊珊
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Changchun University of Chinese Medicine
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Changchun University of Chinese Medicine
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Abstract

The invention provides a Chinese medicine preparation for treating peripheral facial paralysis diseases. The preparation is prepared from reed rhizome, radix saposhnikoviae, scorpio, earthworm, giant typhonium tuber, stiff silkworm and schizonepeta spike in parts by weight. The preparation is a pure Chinese medicine preparation, has the effects of dispelling the wind, activating collaterals and promoting blood circulation to remove meridian obstruction, can be used for comprehensively improving the micro-circulation capability of blood capillaries at the focus, promoting blood circulation, recovering vascular elasticity, supplying sufficient blood to nourish nerve roots, activating nerve cells and recovering the function of facial nerve dominate muscles, and has the effect of treating both symptoms and root causes. The Chinese medicine preparation is rapid to act, rapid to eliminate the clinical symptoms, small in toxic and side effects, uneasy to reoccur, short in treatment course, small in pain and low in expense.

Description

A kind of Chinese medicine preparation for the treatment of infranuclear facial palsy disease
Technical field
The present invention discloses a kind of Chinese medicine preparation for the treatment of infranuclear facial palsy disease, belongs to traditional Chinese medical science pharmaceutical technology sectors.
Background technology
Facial paralysis, i.e. infranuclear facial palsy.Nervus facialis due to domination facial expression muscle group motor function sustains damage and causes facial muscle movements obstacle.The traditional Chinese medical science is referred to as " mouth is out-of-the-way " or " facial hemiparalysis ".It is generally acknowledged be through facial canal nervus facialis part generation acute nonsuppurative inflammation caused by.Its pathological change main manifestations is nervus facialis edema, and myelin or aixs cylinder have degeneration in various degree.
The definite cause of disease for primary disease it be not immediately clear.Due to some patients premorbid often have local wind-engaging, catch a cold or have upper respiratory tract infection medical history, therefore, usually can be considered to local have a cold after, cause the blood vessel generation spasm of trophic nerve, make local neural tissue occur ischemia, edema, pressurized, and cause a disease; Or the rabbit epidemic disease reaction to cause because of viral infection or infection makes nervus facialis generation swelling.Facial neuritis is then because the periostitis in stylomastoid foramen makes nervus facialis pressurized, swelling, blood circulation obstacle and cause facial paralysis.In a word, the reason of primary disease is relevant with viral infection, metainfective immunoreation or local nerve ischemia, and therefore causes the neural swelling that occurs, at it through caused by pressurized during facial canal or ischemia.
Due to before the generation of primary disease, most of patients all has situation that is tired and physically-draining, and motherland's medical science is thought accordingly, and the generation main cause of primary disease is because " healthy energy " is relatively empty in interior, caused by the heresy invasion and attack that Head And Face is had a cold.As sayed in " General Treatise on the Cause and Symptoms of Diseases ", " hemiplegia mouth is askew is body void wind-engaging, make mouth askew also out-of-the-way ".The heresy invasion and attack human body of wind and cold, cause blockage of meridian, QI and blood numbness hinders among passages through which vital energy circulates, causes muscle arteries and veins to lose and supports and primary disease is occurred.
Doctor trained in Western medicine mainly select hormone therapy, vitamin B group treatment, antiviral therapy, vasodilation and improve microcirculation preparation, neurotrophic factor may have certain effect, also can select surgical operation therapy if desired, but clinical efficacy is difficult to fully up to expectations, a lot of patient have finally chosen Chinese medicine acupuncture treatment and oral Chinese medicine treatment.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for the treatment of infranuclear facial palsy disease, is pure Chinese medicinal preparation, has the features such as evident in efficacy, treating both the principal and secondary aspects of a disease.
The Chinese medicine preparation for the treatment of infranuclear facial palsy disease provided by the invention, to it is characterized in that by following raw materials by weight portion than making:
Rhizoma Phragmitis 1 ~ 2 part, Radix Saposhnikoviae 2 ~ 3 parts, Scorpio 6 ~ 8 parts, Pheretima 2 ~ 3 parts, Rhizoma Typhonii (processed) 6 ~ 8 parts, Bombyx Batryticatus 6 ~ 8 parts, Herba Schizonepetae 1 ~ 2 part.
The Chinese medicine preparation of described treatment infranuclear facial palsy disease, preferred following raw materials by weight portion is than making:
Rhizoma Phragmitis 1 part, Radix Saposhnikoviae 2 parts, Scorpio 6 parts, Pheretima 2 parts, Rhizoma Typhonii (processed) 6 parts, Bombyx Batryticatus 6 parts, Herba Schizonepetae 1 part.
the preparation method of the Chinese medicine preparation for the treatment of infranuclear facial palsy disease of the present invention, comprises the following steps:
Take above seven flavor medicine thing in proportion, 60 ~ 80 DEG C dry, pulverize into 100 order fine powders, put sterilizing in Sterilization tank, subpackage, to obtain final product.
Said medicine also can be prepared into the oral formulations such as powder, the watered pill, capsule, tablet according to the preparation technique of traditional Chinese medicine of routine.
Usage and dosage; 3 times/day; 3.3g/ secondary; Oral
Indication: twitch for facial paralysis, prosopodynia, facial spasm, hemiplegia, trigeminal neuralgia, migraine, hemianesthesia, infantile convulsion
side of the present invention separates with pharmacology analysis as follows:
With Scorpio, Bombyx Batryticatus for monarch; Rhizoma Typhonii, Pheretima are minister; Radix Saposhnikoviae, Herba Schizonepetae are assistant; Rhizoma Phragmitis is for making; Primary treatment wind and cold attacks face, causes the facial dermatosis of blockage of meridian.Wind being YANG-pathogen, lightly float using pungent drugs for dispersion and bitter drugs for purgation, easily attacks positive position, if accompany cold and cool gas in wind, wind and cold two heresy is very easily taken advantage of a weak point in opponent's defence and invaded human body Head And Face, causes Head And Face blockage of meridian obstructed, and passages through which vital energy circulates loses foster muscular atrophy and gives up, and sends out as facial paralysis.This for ailment said due to cold or exposure so among this side with Scorpio, Bombyx Batryticatus be monarch with endogenous wind stopping, Pheretima is minister with dredging collateral (Rhizoma Typhonii, Pheretima are altogether for minister).Stomach, through being distributed in face, belongs to yang channel and the many gas of many blood.Cold being a kind of YIN pathogen, presss from both sides with wind facies and attacks face, must violate the warp of stomach sun, makes it sluggish obstructed.So return stomach through the Rhizoma Typhonii reaching women's head-ornaments is minister and up liter falls apart by pungent temperature in this side, with promoting the flow of QI in the collateral by warming the meridian, cooperation Pheretima is that the merit of minister dredging collateral is excellent.Help with the Radix Saposhnikoviae rising the loose through women's head-ornaments that dispel the wind and specially enter the Herba Schizonepetae that yang-energy is lifted in the outer pungent temperature rise of flesh side film, then support warp to promote the production of body fluid and the Rhizoma Phragmitis entering stomach warp for making, meridians must be supported, play the merit of dispelling wind and removing obstruction in the collateral invigorating YANG QI invigorating altogether.
In side, Scorpio, Bombyx Batryticatus are monarch, are longer than dispelling wind and removing obstruction in the collateral, and have the merit of relieving convulsion.The all pungent temperature rise of two medicines is fallen apart, to reach the heresy that YIN-cold attacked by women's head-ornaments.Pheretima is stimulate the menstrual flow to reach the holy product of network, can manage it in underground, and soil is loosened.Get its sensible gas of assaulting fortified position, for that the meridians of stasis blocking can be made to be able to is fluent for minister herein.The pure sun of Rhizoma Typhonii, for wind medicine the yang aspect of yang grass also, the pungent temperature of its property, returns stomach, Liver Channel liter is dissipated to women's head-ornaments, all women's head-ornaments all kinds of diseases and ailments, right deep and tense pulse, with very imitate.Radix Saposhnikoviae person, main air also, specially dispel the wind of positive position, and its gas lift, to the sensible meridians of women's head-ornaments expelling wind and cold, is adjuvant drug with Herba Schizonepetae altogether by this medicine.The pungent temperature of Herba Schizonepetae, enters lung, spleen, Liver Channel and rising, and specially row is outside flesh side film for this medicine, and assistance dredging the meridian is adjuvant drug.Rhizoma Phragmitis promoting production of body fluid with drugs sweet in flavor and cold in nature, returns lung stomach warp, in this case makes, and its mildly regulating cold and heat nourishes meridians, makes just to be so incensed that multiple, and the cold stasis of blood must be removed.
curative effect of the present invention proves:
diagnostic criteria:
1) face can be had to suffer from cold history, and onset is unexpected, be everlasting sleep time outbreak.
2) stiff, numb, the paralysis of side facial muscle, volume stricture of vagina disappear, palpebral fissure becomes large, and sleeping with eyes half-closed is shed tears, and nasolabial fold shoals, and ptosis of labial angle is askew to strong side, can not frown in sick side, knit one's brows, close order, grinningly, drum cheek; Some patients from the beginning of time have pain after ear, also can there is 2/3 hypogeusia or the disease such as disappearance, hyperacusis before Ipsilateral tongue.
3) Ipsilateral volume stricture of vagina disappears, hypophasis, and BellShi levies the positive, and nasolabial fold shoals, and ptosis of labial angle is askew to strong side, lolls placed in the middle.
4) head CT or MRI discovery without exception.
therapeutic effect:cure: 60%, effective: 15%, effective: 20%, invalid: 5%.
Because though the site of pathological change of facial paralysis is at face, but closely bound up with the internal organs, meridians, QI and blood, negative and positive etc. of human body integral.So the conditioning of medication entirety, can yang blood and qi be concocted, reach dredging the meridian, strengthening vital QI to eliminate pathogenic factors, improve facial microcirculation and regulate face nerve to reach the object of curing quick facial paralysis.By the microcirculation ability of the blood capillary of lesions position can be improved rapidly, promote blood circulation, recover blood vessel elasticity, make enough hemotrophic nutritions activate neuron.Full activation neurocyte makes nervus facialis domination muscle function be recovered.
good effect of the present invention is:for pure Chinese medicinal preparation, there is the effect such as dispelling, collateral-activating, promoting blood circulation to remove obstruction in the collateral, the microcirculation ability comprehensively improving the blood capillary of lesions position promotes blood circulation, recover blood vessel elasticity, make enough hemotrophic nutrition nerve rooies activate neuron, make face nerve arrange muscle function and be able to effect that recovery has treating both the principal and secondary aspects of a disease.Drug effect is rapid, and clinical symptom disappearance is fast, and toxic and side effects is little, not easily recurrence, short treating period, and painful little, expense is low.
Detailed description of the invention
To be illustrated further description the present invention by following examples, and do not limit the present invention in any way, under the prerequisite not deviating from technical solution of the present invention, any change that those of ordinary skill in the art made for the present invention easily realize or change all will fall within right of the present invention.
embodiment 1
Prescription: Rhizoma Phragmitis 41.7g, Radix Saposhnikoviae 83.4g, Scorpio 250.2g, Pheretima 83.4g, Rhizoma Typhonii (processed) 250.2g, Bombyx Batryticatus 250.2g, Herba Schizonepetae 41.7g;
Method for making: above seven tastes, dry (60 ~ 80 DEG C), be ground into fine powder (100 order), make 1000g, put sterilizing in Sterilization tank (121 DEG C, 30 minutes), subpackage, to obtain final product.
Specification: every packed 10g; Storage: sealing; Packaging: composite membrane for packaging medicine, 2 bags/box.
embodiment 2
Take Rhizoma Phragmitis 20g part, Radix Saposhnikoviae 40g, Scorpio 120g, Pheretima 40 parts, Rhizoma Typhonii (processed) 120g, Bombyx Batryticatus 120g, Herba Schizonepetae 20g, 60 ~ 80 DEG C dry, pulverize into 100 order fine powders, put sterilizing in Sterilization tank, subpackage, to obtain final product.
embodiment 3
Take Rhizoma Phragmitis 20g, Radix Saposhnikoviae 60g, Scorpio 150g, Pheretima 60g, Rhizoma Typhonii (processed) 150g, Bombyx Batryticatus 150g, Herba Schizonepetae 20g medicine, 60 ~ 80 DEG C dry, pulverize into 100 order fine powders, put sterilizing in Sterilization tank, subpackage, to obtain final product.
following selection portion divides healing case history so that the curative effect of medicine of the present invention to be described.
case 1;
Liu, female, 71 years old, left side face facial hemiparalysis was medical over 3 days.Time medical, disease is seen: left side face facial hemiparalysis, and can not frown, catacleisis is tight, and the gas leakage of the drum cheek is had a meal and had folder meal phenomenon, companion's facial numbness, feels nervous, pain after ear, aversion to wind, and still can sleep at diet, night, two is just normal.Have a medical check-up: left side volume stricture of vagina disappears, catacleisis is not tight, can not frown, the gas leakage of the drum cheek, and Ren Zhonggou is to the right, and left side nasolabial fold shoals, and loll not inclined, physiological reflex exists, and pathologic reflex is not drawn.Western medicine diagnose is infranuclear facial palsy (left side), and tcm diagnosis is facial paralysis (wind and cold attacks network), takes each 3.3g of medicine of the present invention (embodiment 1), and day 3 times is oral.Take 20 days altogether.The state of an illness is fully recovered.
case 2
Rise certain, female, 43 years old, left side face facial hemiparalysis is medical over 7 days.Time medical, disease is seen: left side face facial hemiparalysis, and frown limited, catacleisis owes tight, and the gas leakage of the drum cheek is had a meal and had folder meal phenomenon, companion's facial numbness, feels nervous, dizzy, and without Nausea and vomiting, still can sleep at diet, night, two is just normal.Have a medical check-up: left side volume stricture of vagina disappears, catacleisis owes tight, slightly can frown, the gas leakage of the drum cheek, and Ren Zhonggou is to the right, and left side nasolabial fold shoals, and loll not inclined, physiological reflex exists, and pathologic reflex is not drawn.Western medicine diagnose is infranuclear facial palsy (left side), and tcm diagnosis is facial paralysis (wind and cold attacks network), takes each 3.3g of medicine of the present invention, and day 3 times is oral.Take 15 days altogether.The state of an illness is fully recovered.
case 3
Lee, man, 57 years old, right side face facial hemiparalysis was medical over 1 day.Time medical, disease is seen: right side face facial hemiparalysis, and frown limited, catacleisis owes tight, the drum cheek can not, have a meal and have folder meal phenomenon, companion's facial numbness, to feel nervous, pain after auris dextra, still can sleep at diet, night, two is just normal.Have a medical check-up: right side volume stricture of vagina disappears, catacleisis is not tight, can not frown, the gas leakage of the drum cheek, and Ren Zhonggou is to the left, and right side nasolabial fold shoals, and loll not inclined, physiological reflex exists, and pathologic reflex is not drawn.Western medicine diagnose is infranuclear facial palsy (right side), and tcm diagnosis is facial paralysis (wind and cold attacks network), takes each 3.3g of medicine of the present invention, and day 3 times is oral.Take 18 days altogether.The state of an illness is clearly better.

Claims (3)

1. treat a Chinese medicine preparation for infranuclear facial palsy disease, by following raw materials by weight portion than making:
Rhizoma Phragmitis 1 ~ 2 part, Radix Saposhnikoviae 2 ~ 3 parts, Scorpio 6 ~ 8 parts, Pheretima 2 ~ 3 parts, Rhizoma Typhonii (processed) 6 ~ 8 parts, Bombyx Batryticatus 6 ~ 8 parts, Herba Schizonepetae 1 ~ 2 part.
2. the Chinese medicine preparation for the treatment of infranuclear facial palsy disease according to claim 1, by following raw materials by weight portion than making:
Rhizoma Phragmitis 1 part, Radix Saposhnikoviae 2 parts, Scorpio 6 parts, Pheretima 2 parts, Rhizoma Typhonii (processed) 6 parts, Bombyx Batryticatus 6 parts, Herba Schizonepetae 1 part.
3. the preparation method of the Chinese medicine preparation for the treatment of infranuclear facial palsy disease according to claim 1 and 2, comprises the following steps:
Take above seven kinds of raw materials in proportion, 60 ~ 80 DEG C dry, pulverize into 100 order fine powders, put sterilizing in Sterilization tank, subpackage, to obtain final product.
CN201310209507.3A 2013-05-31 2013-05-31 Chinese medicine preparation for treating peripheral facial paralysis diseases Active CN103263598B (en)

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104958465A (en) * 2015-08-03 2015-10-07 房春燕 Traditional Chinese medicine used for treating facioplegia
CN105663820A (en) * 2016-01-30 2016-06-15 王廷波 Traditional Chinese medicine composition for treating facial nerve palsy

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
李刚 等.第一节 面瘫.《中医口腔病症学》.人民军医出版社,1989,第336、339页. *
面瘫宁加减治疗面瘫的临床疗效观察;高丽红 等;《黑龙江中医药》;20100315;第30页 *

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