CN101559130A - Plant drug compound preparation for treating asthma in children and preparation thereof - Google Patents
Plant drug compound preparation for treating asthma in children and preparation thereof Download PDFInfo
- Publication number
- CN101559130A CN101559130A CNA2009100518289A CN200910051828A CN101559130A CN 101559130 A CN101559130 A CN 101559130A CN A2009100518289 A CNA2009100518289 A CN A2009100518289A CN 200910051828 A CN200910051828 A CN 200910051828A CN 101559130 A CN101559130 A CN 101559130A
- Authority
- CN
- China
- Prior art keywords
- drug compound
- preparation
- compound preparation
- plant drug
- plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a plant drug compound preparation for treating asthma in children, which comprises water extracts of the following raw materials: 1 to 8 percent of mix-fried ephedra, 1 to 12 percent of almond, 1 to 12 percent of perilla fruit, 1 to 12 percent of radish seed, 1 to 12 percent of earthworm, 1 to 8 percent of peach kernel, 1 to 12 percent of zanthoxylum seed, 1 to 12 percent of baical skullcap root, and 1 to 5 percent of raw licorice; and the preparation of the plant drug compound preparation comprises that: composition of the plant drugs in the proportion is soaked in cold water for 20 to 30 minutes, decocted by intense fire to be boiled, and then decocted by slow fire for 15 minutes, drug juice is poured out, and the operation is repeated, and decoction liquid of the twice is combined to obtain decoction; and the decoction is stood, supernatant fluid is filtered, condensed, cooled naturally, and added with alcohol of which the volume is 1 to 4 times of that of the supernatant fluid, the mixture is precipitated, supernatant fluid is filtered and condensed to thick extract, and the thick extract is added with pharmaceutic adjuvant. The invention also relates to application of the plant drug compound preparation in preparing related medicaments for treating the asthma in children. The plant drug compound preparation has the advantages of high curative effect, no toxic and side effects, low price and the like; and the preparation method is simple, and has low cost and good application prospect.
Description
Technical field
The invention belongs to the plant drug compound preparation and the preparation field thereof of treatment asthma, particularly relate to a kind of plant drug compound preparation and preparation thereof for the treatment of infantile asthma.
Background technology
Asthma is children's's a kind of commonly encountered diseases and frequently-occurring disease.According to investigations, the whole world has 1.6 hundred million asthma patients approximately, and the number of patients of China also surpasses 2,000 ten thousand.The prevalence of 0～14 years old urban children of investigation China in 2000 is 0.5～3.4%, average out to 1.97%, and be ascendant trend year by year.The main feature of asthma is air flue chronic inflammatory disease and airway hyperreactivity, show as pant, symptoms such as tachypnea, uncomfortable in chest, cough show effect repeatedly, can influence the pulmonary function of infant, threat to life when serious.Doctor trained in Western medicine is mainly taked method treatment asthma such as antiinflammatory, diastole bronchus, reduction airway hyperreactivity.In recent years, all advocate by GINA scheme treatment infantile asthma in the whole world, and China is also carrying out energetically.But a lot of infants can not correctly be grasped the hormone anapnotherapy in clinical practice, also there is the part head of a family to worry to use the side effect that hormone brings and is reluctant to use, though bronchodilators can be controlled bronchospasm rapidly and relieving asthma, but increase the weight of airway inflammation and airway hyperreactivity sometimes, the therapeutic effect that causes present infantile asthma is not very good.
Chinese medicine thinks that expectorant is long-standing of asthma morbidity.The plain body lung of children's spleen kidney deficiency, water liquid dysfunction of the spleen in transportation and transformation condenses and is expectorant, and phlegm retention is stayed volt, obstructing airway, the stagnation of QI is in interior, and the stagnation of QI then blood operation is not smooth, forms blood stasis.Expectorant, the stasis of blood, gas three become trouble mutually and cause asthma to be shown effect repeatedly, and delay is difficult.Modern medicine study finds that the air flue chronic inflammatory disease of asthma often shows as edema, the blood capillary hyperemia of air flue mucosa, pathological states such as microcirculation disturbance.The traditional Chinese medical science is paid attention to organic conception and determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, advocates the principle of " take stopgap measures, effect a permanent cure at ordinary times when sending out ", has a clear superiority in treatment of asthma.
Summary of the invention
Technical problem to be solved by this invention provides a kind of plant drug compound preparation and preparation thereof for the treatment of infantile asthma, advantage such as this plant drug compound preparation has the curative effect height, has no side effect, price is low, be based on the asthma morbidity originally---" the long-standing stasis of blood of latent phlegm ", dispersing and descending lung-QI takes stopgap measures with Dingchuan, dissipating phlegm and removing blood stasis is to remove Yin Zhiben, to reach the effect for the treatment of both the principal and secondary aspects of a disease; And preparation method is simple, and cost is low, and is environmentally friendly, in treatment infantile asthma and the cough of the expectorant stasis of blood good prospects for application arranged.
A kind of plant drug compound preparation for the treatment of infantile asthma of the present invention, its plant amedica compositions comprises the water extract of following weight portion:
Herba Ephedrae (processed) 1-8% Semen Armeniacae Amarum 1-12% Fructus Perillae 1-12% Semen Raphani 1-12% Pheretima 1-12%
Semen Persicae 1-8% Semen zanthoxyli 1-12% Radix Scutellariae 1-12% Radix Glycyrrhizae 1-5%.
In the plant drug compound preparation of described treatment infantile asthma, its plant amedica compositions comprises the water extract of following weight portion:
Herba Ephedrae (processed) 6% Semen Armeniacae Amarum 9% Fructus Perillae 9% Semen Raphani 9% Pheretima 9%
Semen Persicae 6% Semen zanthoxyli 9% Radix Scutellariae 9% Radix Glycyrrhizae 3%.
Described plant drug compound preparation be by oral, snuffing is gone into, the mode of rectum or parenteral, local application is applied to the patient who needs this treatment.
A kind of preparation method for the treatment of the plant drug compound preparation of infantile asthma of the present invention comprises:
(1) the plant amedica compositions of said ratio is used cold water soak 20-30 minute, the water yield was covered powder, and medicine is submerged;
(2) decoct with high heat earlier boil to water after, use slow fire instead and fried in shallow oil again 15 minutes, medicine juice is poured out;
(3) continue to add cold water and covered powder and get final product, soaking-free, the operation of repeating step (2) merges above-mentioned secondary decocting liquid, promptly gets decoction;
(4) above-mentioned decoction is left standstill, the leaching supernatant concentrates, and puts coldly, makes concentrated solution, adds the ethanol of 1-4 times of volume, stir while adding, and precipitation 12～24h, the leaching supernatant is concentrated into thick extractum, adds pharmaceutic adjuvant, makes plant drug compound preparation and gets final product.
Described plant drug compound preparation is made solid preparation such as tablet, powder, granule or capsule, makes liquid preparation such as water or oiliness suspending agent etc. or other liquid preparation such as syrup, mixture or oral liquid; When being used for parenteral, can be made into solution, water or the oiliness suspending agent of injection; During topical, be made into cream, ointment, patch, spray or subcutaneous implant;
The consumption of described plant drug compound preparation is according to the type and the order of severity adjustment of route of administration, patient's age, body weight, the disease of being treated, its, dosage was decoction 150-200ml every day, divide and take for 2-4 time, 1 card/day, syrup or mixture 20～30ml, tablet or capsule 6-12 grain, granule 15～30g or oral liquid 10～20ml can use by one or many;
Described plant drug compound preparation is made slow releasing tablet or coated tablet.
It is monarch that plant drug compound preparation of the present invention is relievingd asthma with Herba Ephedrae (processed), reduces phlegm with Semen Armeniacae Amarum, Fructus Perillae, Semen Raphani, and the Semen Persicae blood stasis dispelling is a minister, and assistant makes with Radix Glycyrrhizae with dried Pheretima, Semen zanthoxyli, Radix Scutellariae.All medicines are usefulness together, plays dissipating phlegm and removing blood stasis altogether, the effect of lowering the adverse-rising QI to subdue asthma.
Monarch drug Herba Ephedrae bitter in the mouth is warm in nature, diaphoresis is arranged, relievings asthma, the effect of diuretic.Record Herba Ephedrae among the Zhang Xichun " Records of Tradition Chinese and Western Medicine in Combination " " main cough with dyspnea person, with its kind search lung-wind syndrome hold concurrently can the eliminating the pathogens from the lung Dingchuan also ", its removing blood stasis with potent drugs person, with its " can deeply amass among the expectorant blood coagulation, and the medicine of the hard blood stasis dispelling that disappears can together with to prove effective also." modern experimentation confirms; ephedrine, pseudoephedrine, Herba Ephedrae volatile oil are the effective ingredient that Herba Ephedrae is relievingd asthma; the ephedrine bronchial smooth muscle that can relax, and the bronchus of spasticity are had obvious spasmolysis, 2; 3; 5, and 6-tetramethylpyazine and terpinenol are definite recently compositions of relievining asthma, and have and relieving asthma; antiinflammatory, the effect of relieving cough and expelling phlegm.
With Semen Armeniacae Amarum, Fructus Perillae, Semen Raphani, Semen Persicae is ministerial drug, reduces phlegm and takes into account blood stasis dispelling.The Semen Armeniacae Amarum bitter in the mouth is hot little sweet, can " cough-relieving be coughed, expectorant lung moistening, the intestine moistening stomach, the flour that disappears is long-pending, the therapeutic method to keep the adverse QI flowing downwards ", and modern study confirms that its effective ingredient amygdaloside eliminates the phlegm, antitussive, relieving asthma, antiinflammatory is regulated effects such as immunity.The Fructus Perillae acrid in the mouth is warm in nature, but “ Po Disorder knot, five diaphragms that disappear, antitussive, profit cardiopulmonary, eliminating phlegm-retention ", there is report to inject perilla oil to mouse peritoneal, can obviously prolong the incubation period of the outbreak of panting, obviously reduce the cough number of times.Semen Raphani Xin Ganping can " therapeutic method to keep the adverse QI flowing downwards Dingchuan be controlled expectorant, helps digestion, and remove to expand ", the effect of antitussive is arranged, eliminate the phlegm, relievining asthma.Experiment shows that living Semen Raphani alcohol extract and Semen Raphani (parched) ether extract have significant antitussive and phlegm-dispelling functions, and frying living Semen Raphani water extract has certain antiasthmatic effect.The Semen Persicae bitter in the mouth is flat, and " pathogen is killed small worm for main blood stasis, Xue Bi mass in the abdomen ", modern study confirms that it has the hemodynamics of improvement, antithrombotic to form effects such as antiinflammatory.
With dried Pheretima, Semen zanthoxyli, Radix Scutellariae is adjuvant drug.Dried Pheretima is salty-cold, and pharmacological research finds that the Pheretima extracting solution has antithrombotic, reduces blood viscosity and effects such as platelet aggregation, enhancing erythrocyte membrane stability.Animal and experiment showed, that lumbricin in the Pheretima can alleviate Cavia porcellus asthma and the isolated tracheal sheet spasm due to the histamine, the clinical studies show lumbricin is all effective in cure to the men and women patient of all ages and classes bronchial asthma attack, and total effective rate is greater than 76%; Succinic acid, hypoxanthine have significant bronchorelaxing activity in the Pheretima, and the bronchoconstriction that can cause antihistamine and pilocarpine; Cavia porcellus is drawn and breathes heavily test and show, the earthworm decoction antiasthmatic effect may by with histamine competition H receptor, thereby stop the enhancing of tracheospasm and capillary permeability; Pharmacological research finds that Pheretima can reduce the effect of total cellular score in the sensitization BALF in Asthma Guinea-pigs, albumin content and leukotriene level.The Semen zanthoxyli bitter in the mouth is cold, can " control bloated, Dingchuan, and tinnitus due to deficiency of the kidney ", " deciding phlegm dyspnea "; Experiment showed, that Semen zanthoxyli has spasmolytic and relievings asthma and the antiallergic dual function, can suppress the release of crossing sensitive media slow reacting substance-A (SRS-A) that mastocyte produces; Semen zanthoxyli energy diastole bronchial smooth muscle, the Cavia porcellus asthma that spraying histamine is excited has inhibitory action.The Radix Scutellariae bitter in the mouth is cold, " fire of the clear part of the body cavity above the diaphragm housing the heart and lungs of withered person, expectorant promoting the circulation of QI, Dingchuan "; Modern study confirms that Radix Scutellariae has the effect of antiinflammatory, antiallergic, and its antiinflammatory action is with the generation that suppresses inflammatory mediator and discharge relevant; Recent research shows that baicalin suppresses 5-lipid oxygenase activity and generates the leukotriene chemical compound with blocking-up AA, suppresses antigen and combines with IgE, suppresses mastocyte and discharges histamine, thereby play the effect of antiallergic action.
With the Radix Glycyrrhizae is messenger drug.The Radix Glycyrrhizae sweet in the mouth is flat, studies confirm that it has the effect of adrenocortical hormone sample, antiinflammatory, antiallergic action, antitussive are arranged, eliminates the phlegm, effect such as anticoagulant; Isoglycyrrhiza acid in the Radix Glycyrrhizae and glycyrrhizin have inhibitory action to the activity of transparent ester acid enzyme and the histamine release that immunostimulation is induced mastocyte; Flavone monomeric compound Licochalcone A and B can suppress the biosynthesis of leukotriene in people's polymorph neutrophile leucocytes in the Radix Glycyrrhizae.
Beneficial effect
Advantages such as (1) plant drug compound preparation of the present invention has the curative effect height, has no side effect, price is low, be based on the asthma morbidity this---" the long-standing stasis of blood of latent phlegm ", dispersing and descending lung-QI are taken stopgap measures with Dingchuan, and dissipating phlegm and removing blood stasis is to remove Yin Zhiben, to reach the effect for the treatment of both the principal and secondary aspects of a disease;
(2) this preparation method is simple, and cost is low, and is environmentally friendly, in treatment infantile asthma and the cough of the expectorant stasis of blood good prospects for application arranged.
The specific embodiment
Below in conjunction with specific embodiment, further set forth the present invention.Should be understood that these embodiment only to be used to the present invention is described and be not used in and limit the scope of the invention.Should be understood that in addition those skilled in the art can make various changes or modifications the present invention after the content of having read the present invention's instruction, these equivalent form of values fall within the application's appended claims institute restricted portion equally.
Embodiment 1
(1) get Herba Ephedrae (processed) 6g, Semen Armeniacae Amarum 9g, Fructus Perillae 9g, Semen Raphani 9g, Pheretima 9g, Semen Persicae 6g, Semen zanthoxyli 9g, Radix Scutellariae 9g, Radix Glycyrrhizae 3g uses cold water soak 20-30 minute, and the water yield was covered powder, and medicine is submerged;
(2) decoct with high heat earlier boil to water after, use slow fire instead and fried in shallow oil again 15 minutes, medicine juice is poured out;
(3) continue to add cold water and covered powder and get final product, soaking-free, the operation of repeating step (2) merges above-mentioned secondary decocting liquid, promptly gets decoction;
(4) above-mentioned decoction is left standstill, the leaching supernatant concentrates, and puts coldly, makes concentrated solution, add the ethanol of 1-4 times of volume, stir while adding, precipitation 12～24h, the leaching supernatant is concentrated into thick extractum, add pharmaceutic adjuvant, vacuum drying is pulverized and is granulated, and is pressed into tablet or fills encapsulated.
Embodiment 2
(1) get Herba Ephedrae (processed) 9g, Semen Armeniacae Amarum 15g, Fructus Perillae 15g, Semen Raphani 15g, Pheretima 15g, Semen Persicae 9g, Semen zanthoxyli 15g, Radix Scutellariae 15g, Radix Glycyrrhizae 5g uses cold water soak 20-30 minute, and the water yield was covered powder and was got final product, and then all medicines was all down pressed, and medicine is submerged;
(2) decoct with high heat earlier boil to water after, use slow fire instead and fried in shallow oil again 15 minutes, medicine juice is poured out;
(3) continue to add cold water and covered powder and get final product, soaking-free, the operation of repeating step (2) merges above-mentioned secondary decocting liquid, promptly gets decoction;
(4) above-mentioned decoction is left standstill, the leaching supernatant concentrates, and puts coldly, makes concentrated solution, adds the ethanol of 1-4 times of volume, stir while adding, precipitation 12～24h, the leaching supernatant is concentrated into thick extractum, adds pharmaceutic adjuvant, granulate, drying, granulate gets the 20g granule, packing 10g/ bag.
Embodiment 3
(1) get Herba Ephedrae (processed) 4g, Semen Armeniacae Amarum 6g, Fructus Perillae 6g, Semen Raphani 6g, Pheretima 6g, Semen Persicae 4g, Semen zanthoxyli 6g, Radix Scutellariae 6g, Radix Glycyrrhizae 2g uses cold water soak 20-30 minute, and the water yield was covered powder and was got final product, and then all medicines was all down pressed, and medicine is submerged;
(2) decoct with high heat earlier boil to water after, use slow fire instead and fried in shallow oil again 15 minutes, medicine juice is poured out;
(3) continue to add cold water and covered powder and get final product, soaking-free, the operation of repeating step (2) merges above-mentioned secondary decocting liquid, promptly gets decoction;
(4) above-mentioned decoction is left standstill, the leaching supernatant concentrates, and puts cold, make concentrated solution, add the ethanol of 1-4 times of volume, stir while adding, precipitation 12～24h, the leaching supernatant is concentrated into thick extractum, adds pharmaceutic adjuvant, makes mixture, oral liquid or syrup.
Embodiment 4
Find by clinical experimental research, the plant drug compound preparation of the present invention IFN-γ level in asthmatic model mice serum and the bronchoalveolar lavage fluid (BALF) that can obviously raise, reduce the IL-4 level, rising IFN-γ/IL-4 ratio obviously reduces collagen fiber on the mouse bronchial wall.Can also significantly reduce MIP-1 α and IgE level, downward modulation CD86 developed by molecule significantly reduces air flue collagen fiber deposition; Can significantly reduce the IgE level, alleviate the asthma disease symptom; Alleviate air flue mucous epithelium damage, reduce the air flue cell infiltration, alleviate bronchial wall and around between matter hyperemia, edema, reduce airway walls collagen fiber deposition, improve airway remodeling.Generally speaking, plant drug compound preparation of the present invention has therapeutical effect to the asthma pathogenic process, can improve airway inflammation and airway remodeling to a certain extent, alleviates the asthma disease symptom.
Claims (7)
1. plant drug compound preparation for the treatment of infantile asthma, its plant amedica compositions comprises the water extract of following weight portion:
Herba Ephedrae (processed) 1-8% Semen Armeniacae Amarum 1-12% Fructus Perillae 1-12% Semen Raphani 1-12% Pheretima 1-12%
Semen Persicae 1-8% Semen zanthoxyli 1-12% Radix Scutellariae 1-12% Radix Glycyrrhizae 1-5%.
2. a kind of plant drug compound preparation for the treatment of infantile asthma according to claim 1 is characterized in that: in the plant drug compound preparation of described treatment infantile asthma, its plant amedica compositions comprises the water extract of following weight portion:
Herba Ephedrae (processed) 6% Semen Armeniacae Amarum 9% Fructus Perillae 9% Semen Raphani 9% Pheretima 9%
Semen Persicae 6% Semen zanthoxyli 9% Radix Scutellariae 9% Radix Glycyrrhizae 3%.
3. a kind of plant drug compound preparation for the treatment of infantile asthma according to claim 1 is characterized in that: this plant drug compound preparation be by oral, snuffing is gone into, the mode of rectum or parenteral, local application is applied to the patient of this treatment of needs.
4. preparation method for the treatment of the plant drug compound preparation of infantile asthma comprises:
(1) the plant amedica compositions of said ratio is used cold water soak 20-30 minute, the water yield was covered powder and was got final product, and medicine submerges;
(2) decoct with high heat earlier boil to water after, use slow fire instead and fried in shallow oil again 15 minutes, medicine juice is poured out;
(3) continue to add cold water and covered powder and get final product, soaking-free, the operation of repeating step (2) merges above-mentioned secondary decocting liquid, promptly gets decoction;
(4) above-mentioned decoction is left standstill, the leaching supernatant concentrates, and puts coldly, makes concentrated solution, adds the ethanol of 1-4 times of volume, stir while adding, and precipitation 12～24h, the leaching supernatant is concentrated into thick extractum, adds pharmaceutic adjuvant, makes plant drug compound preparation and gets final product.
5. a kind of preparation method for the treatment of the plant drug compound preparation of infantile asthma according to claim 4, it is characterized in that: this plant drug compound preparation is made solid preparation such as tablet, powder, granule or capsule, makes liquid preparation such as water or oiliness suspending agent etc. or other liquid preparation such as syrup, mixture or oral liquid; When being used for parenteral, can be made into solution, water or the oiliness suspending agent of injection; During topical, be made into cream, ointment, patch, spray or subcutaneous implant.
6. according to the preparation method of claim 4 or 5 described plant drug compound preparations, it is characterized in that: the consumption of this plant drug compound preparation is according to the type and the order of severity adjustment of route of administration, patient's age, body weight, the disease of being treated, its, dosage was decoction 150-200ml, syrup or mixture 20～30ml, tablet or capsule 6-12 grain, granule 15～30g or oral liquid 10～20ml every day, and one or many is used.
7. the preparation method of plant drug compound preparation according to claim 6, it is characterized in that: this plant drug compound preparation is made slow releasing tablet or coated tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2009100518289A CN101559130A (en) | 2009-05-22 | 2009-05-22 | Plant drug compound preparation for treating asthma in children and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2009100518289A CN101559130A (en) | 2009-05-22 | 2009-05-22 | Plant drug compound preparation for treating asthma in children and preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101559130A true CN101559130A (en) | 2009-10-21 |
Family
ID=41218221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2009100518289A Pending CN101559130A (en) | 2009-05-22 | 2009-05-22 | Plant drug compound preparation for treating asthma in children and preparation thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101559130A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101966251A (en) * | 2010-10-09 | 2011-02-09 | 上海中医药大学附属岳阳中西医结合医院 | Medicinal composition for preventing and treating bronchial asthma and preparation and application thereof |
| CN102423350A (en) * | 2011-12-09 | 2012-04-25 | 上海市中医医院 | Medicine for treating childhood bronchial asthma and application of medicine |
| CN104984311A (en) * | 2015-08-10 | 2015-10-21 | 青岛蓝盛洋医药生物科技有限责任公司 | Traditional Chinese medicine composite for treating child asthma and preparation method thereof |
| CN107320709A (en) * | 2017-09-04 | 2017-11-07 | 上海市中医医院 | A kind of Chinese medicine composition for treating asthma in children |
| CN109999090A (en) * | 2019-05-15 | 2019-07-12 | 南京中医药大学 | It is a kind of to have effects that treat the drug and the preparation method and application thereof of asthma in children |
| CN115869357A (en) * | 2022-11-30 | 2023-03-31 | 无锡市中医医院(无锡市中医研究所、无锡市中医骨伤中心、无锡市中医健康管理中心、无锡市龙砂医学流派研究院) | Medicinal bacterium composition for treating asthma and preparation method and application thereof |
-
2009
- 2009-05-22 CN CNA2009100518289A patent/CN101559130A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101966251A (en) * | 2010-10-09 | 2011-02-09 | 上海中医药大学附属岳阳中西医结合医院 | Medicinal composition for preventing and treating bronchial asthma and preparation and application thereof |
| CN102423350A (en) * | 2011-12-09 | 2012-04-25 | 上海市中医医院 | Medicine for treating childhood bronchial asthma and application of medicine |
| CN104984311A (en) * | 2015-08-10 | 2015-10-21 | 青岛蓝盛洋医药生物科技有限责任公司 | Traditional Chinese medicine composite for treating child asthma and preparation method thereof |
| CN107320709A (en) * | 2017-09-04 | 2017-11-07 | 上海市中医医院 | A kind of Chinese medicine composition for treating asthma in children |
| CN109999090A (en) * | 2019-05-15 | 2019-07-12 | 南京中医药大学 | It is a kind of to have effects that treat the drug and the preparation method and application thereof of asthma in children |
| CN109999090B (en) * | 2019-05-15 | 2021-09-14 | 南京中医药大学 | Medicine with efficacy of treating infantile asthma and preparation method and application thereof |
| CN115869357A (en) * | 2022-11-30 | 2023-03-31 | 无锡市中医医院(无锡市中医研究所、无锡市中医骨伤中心、无锡市中医健康管理中心、无锡市龙砂医学流派研究院) | Medicinal bacterium composition for treating asthma and preparation method and application thereof |
| CN115869357B (en) * | 2022-11-30 | 2024-01-16 | 无锡市中医医院(无锡市中医研究所、无锡市中医骨伤中心、无锡市中医健康管理中心、无锡市龙砂医学流派研究院) | Medicinal fungus composition for treating asthma and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102100856A (en) | Nano traditional Chinese medicine for treating bronchial asthma and preparation technology | |
| CN101559130A (en) | Plant drug compound preparation for treating asthma in children and preparation thereof | |
| CN103933425A (en) | Traditional Chinese medicine composition for treating lung cancer and preparation method thereof | |
| CN113577140A (en) | Traditional Chinese medicine composition for treating neocoronary pneumonia and preparation method and application thereof | |
| CN104013861A (en) | Traditional Chinese medicine composition for treating infantile pneumonia | |
| CN103182064A (en) | Medicine for treating cough due to wind-cold evil and preparation method thereof | |
| CN103784638A (en) | Traditional Chinese medicine decoction used for preventing and treating children heat asthma | |
| CN102343029B (en) | Chinese medicinal composition preparation for treating cough and preparation method thereof | |
| CN104042971A (en) | Medicine composition for treating yin deficiency toxic heat lung cancer and preparation method thereof | |
| CN103751349B (en) | Traditional Chinese medicine composition for treating rhinitis and preparation method of composition | |
| CN103191331B (en) | Traditional Chinese medicine composition for treating bronchial asthma in remission stage | |
| CN105012817B (en) | A kind of cough-relieving is relievingd asthma and the Chinese medicine composition of eliminating the phlegm and preparation method thereof | |
| CN105327182A (en) | Medicine for treating child pertussis and preparation method thereof | |
| CN102935214B (en) | Traditional Chinese medicinal composition for treating uremia | |
| CN103301230B (en) | Oral medicine for treating allergic rhinitis together with nasal spray | |
| CN102228633A (en) | Traditional Chinese medicine for treating blood heat and toxic type nosebleed of children and preparation method thereof | |
| CN106138755B (en) | Dendrobium officinale mixture | |
| CN104027426A (en) | Traditional Chinese medicine drops for treating rhinitis | |
| CN103721229A (en) | Traditional Chinese medicinal composition for treating infantile cough and asthma and preparation method thereof | |
| CN108030887A (en) | A kind of Chinese materia medica syrup for being used to treat cough variant asthma in childhood: prednison comparing | |
| CN104189870A (en) | Traditional Chinese medicine for treating allergic asthma | |
| CN105998963A (en) | Traditional Chinese medicine composition for treating chronic renal failure and application of traditional Chinese medicine composition for treating chronic renal failure | |
| CN1256132C (en) | Chinese medicinal preparation for treating infant tracheitis | |
| CN105288143A (en) | Traditional Chinese medicine composition for treating asthma | |
| CN107362311B (en) | Medicine 'Baicheqingjin' for treating cough |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Open date: 20091021 |