CN103721229A - Traditional Chinese medicinal composition for treating infantile cough and asthma and preparation method thereof - Google Patents
Traditional Chinese medicinal composition for treating infantile cough and asthma and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal composition for treating infantile cough and asthma and a preparation method thereof. The composition is prepared from the raw materials of codonopsis pilosula, dried tangerine peel, tatarian aster root, cassia twig, poria, ephedra, asarum and dried ginger. The invention also provides the preparation method of the traditional Chinese medicinal composition for treating infantile cough and asthma. The composition for treating yang-deficiency type infantile cough and asthma can be used for warming cold phlegm, calming panting and suppressing cough, and has a remarkable curative effect to infantile cough and asthma.
Description
Technical field
The present invention relates to pharmaceutical sanitary field, be specifically related to a kind of Chinese medicine composition for the treatment of infantile asthma and preparation method thereof.
Background technology
Infantile asthma belongs to a kind of chronic airway inflammation disease, it is a kind of immune inflammation, be characterized in that Airway reversibility is narrow and cause dyspnea, its clinical manifestation be out of breath, cough, cough up phlegm, can hear wheezing sound in dyspnea, lung, while especially exhaling, wheezing sound is more obvious.Infantile asthma outbreak can be alleviated with suppressing panting calming medicine time, also can spontaneous remission, and that after infantile asthma outbreak, recovers is normal, can there is no symptom completely.If cough with asthma acutely affects sleep and feed, also treatment cough-relieving combined treatment before syllabus, also comprising eliminates the phlegm reduces phlegm, and alleviates respiratory mucosa edema, recovers intima of the trachea ciliary action etc.
Pathogeny to Cough Variant Asthma in Children at present, Most scholars thinks that with the mechanism of typical asthma be consistent, is a kind of airway allergy inflammation.The order of severity that is only course advancement degree difference or airway inflammation differs.
The traditional Chinese medical science is thought the spleen and stomach in children weakness, easily for breast food, raw food, accumulated heat are hindered, and dysfunction of the spleen in transportation, water paddy is can not biochemistry precise and tiny, and the anti-disease that leads to, above stores in lung, and obstruction of QI-passage must not be declared the clearing heat in QI system of lung and is reached and cough with asthma, and this is " the spleen being the source of producing phlegm, the lung being the utensil for storing phlegm ".Also can be because of children's's innate deficiency, plain body lung spleen deficiency, because of Exogenous cough and asthma, does not with the passing of time heal, and can consume the moon of feeling frustrated, and occurs cough and asthma due to lung deficiency or deficiency of YIN cough with asthma.Phlegm-damp in internal injury cough with asthma, expectorant heat, liver-fire mostly are the domination of pathogen and just should.Cloudy body fluid deficiency consumption cough with asthma belongs to empty, or deficiency complicated with excess.Lung qi is unclear, lose in a surname respectful, superinverse is uttered a word and is caused that cough with asthma is its Characteristics of Syndromes.As follows in conjunction with child's feature typing:
(1) cough and asthma due to lung deficiency cough with asthma is prolonged, cough and unable, and sputum rareness, faint low voice, pale complexion, moving breathe hard, the empty hyperhidrosis of body, pale and tender tongue, thin white fur of tongue, thready pulse without strength;
(2) heavy cough of phlegm dampness in lungs, suffocated breathing uncomfortable in chest, anorexia, the white thickness of abundant expectoration color, white and greasy fur, soft pulse is sliding;
(3) expectorant heat stagnation pulmonary cough is breathed slightly, the thick Huang of abundant expectoration, restlessness and fever with thirst, red tongue, yellow and greasy fur, slippery and rapid pulse.
(4) to cough expectorant of a specified duration few for deficiency of YIN cough with asthma, cough up tell not well, the sticky or folder blood streak of expectorant, dry mouth and throat, feverish sensation in the palms and soles, red tongue, few tongue, thready and rapid pulse.
Conventional Dietotherapy method has:
1, Radix Raphani Pericarpium Citri Reticulatae soup: 1 of white turnip, 5 of Radix orixae japonicaes are put in section, Rhizoma Zingiberis Recens 10g, Pericarpium Citri Reticulatae 5g, boils soup, then with crystal sugar 50g.Be used for the early stage of infantile asthma, cough with asthma frequently shows effect, and throat is itched, heavy cough, and expectorant is rare clearly in vain.
2, " Luohan " fruit tea: Guangxi Fructus Momordicae 9g, is decocted in water for oral dose.Not well for infantile asthma, the yellow thickness of expectorant, is not easy to bring up.
3, Sucus Luffae: autumn Fructus Luffae, extracting juice, drinks after water proof steaming.For the infantile asthma time longer, abundant expectoration, yellow skin thickness, coughs up and tells not wellly, or has hot fishy smell.
4, Bulbus Fritillariae Cirrhosae pears: Bulbus Fritillariae Cirrhosae 5g, crystal sugar 15g and pears are with steaming, for infantile asthma abundant expectoration, yellow skin and thickness.
5, Semen Coicis Rhizoma Dioscoreae Semen Benincasae medicated porridge: Semen Coicis 50g, Rhizoma Dioscoreae, the each 100g of Semen oryzae sativae, Semen Benincasae 50g, with cooking congee food.For infantile asthma abundant expectoration, color is white.
6, Semen Armeniacae Amarum Radix Raphani pig lung decoction: each 1 of Pulmonis Sus domestica, white turnip, stripping and slicing, Semen Armeniacae Amarum 9g, stewes thoroughly cooked food altogether.For chronic cough in children do not heal, movable after asthma, person out of breath.
7, Bulbus Lilii pig lung decoction
Infantile asthma can have a strong impact on child's sleep, rest and study, therefore should diagnose early and actively treat.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of infantile asthma;
Another object of the present invention is to provide a kind of Chinese medicine composition preparation method for the treatment of infantile asthma.
The object of the invention is to realize by following technical scheme:
The Chinese medicine composition for the treatment of infantile asthma of the present invention is to be prepared from by the raw material containing following weight portion:
Radix Codonopsis 20-40 part, Pericarpium Citri Reticulatae 20-30 part, Radix Asteris 20-30 part, Poria 10-30 part, Ramulus Cinnamomi 5-15 part, Herba Ephedrae 5-15 part, Herba Asari 5-10 part, Rhizoma Zingiberis 5-10 part.
Preferably, be to be prepared from by the raw material containing following weight portion:
Radix Codonopsis 25-35 part, Pericarpium Citri Reticulatae 15-25 part, Radix Asteris 25-25 part, Poria 15-25 part, Ramulus Cinnamomi 8-12 part, Herba Ephedrae 8-12 part, Herba Asari 6-9 part, Rhizoma Zingiberis 6-9 part.
More preferably, be to be prepared from by the raw material containing following weight portion:
30 parts of Radix Codonopsis, 20 parts of Pericarpium Citri Reticulataes, 20 parts of Radix Asteriss, 20 parts, Poria, 10 parts of Ramulus Cinnamomi, 10 parts, Herba Ephedrae, 8 parts of Herba Asaris, 8 parts of Rhizoma Zingiberiss.
Below crude drug source of the present invention:
Radix Codonopsis: this product is Campanulaceae Radix Codonopsis Codonopsispilosula(Franch.) Nannf., element flower Radix Codonopsis (RADIX CODONOPSIS PILOSULAE from Northwest of China) CodonopsispilosulaNannf.var.modesta(Nannf.) dry root of L.T.Shen or radix codonpsis tangshen CodonopsistangshenOliv..Excavate autumn, cleans, and dries.[nature and flavor] are sweet, flat.[return through] returns spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Pericarpium Citri Reticulatae: be the dry mature skin of rutaceae orange and variety thereof.[nature and flavor] are bitter, pungent, temperature.[return through] returns lung, spleen channel.[function cures mainly] regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Radix Asteris, another name: Radix Asteris.For the dry root and rhizome of feverfew Radix Asteris Aster tataricus L. f..Warm in nature, bitter in the mouth, pungent.Nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.For abundant expectoration breath with cough, new chronic cough is coughed, chronic cough hemoptysis.
Poria is the dry sclerotia of On Polyporaceae Poria Poriacocos (Schw.) Wolf.Record in one the 166th page of < < Chinese Pharmacopoeia > > version in 2005.[nature and flavor] are sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.
Ramulus Cinnamomi: this product is the dry twig of canella Cortex Cinnamomi CinnamomumcassiaPresl.Spring, Xia Erji gather, and except defoliation, dry, or section are dried.[nature and flavor] acrid, sweet, warm.[return through] GUIXIN, lung, urinary bladder channel.[function cures mainly] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Herba Ephedrae: Ephedra sinica Ephedra sinica Stapf, claims again Herba Ephedrae, magnificent Herba Ephedrae.Ephedraceae, Ephedra.Attach most importance to and want medicinal plants, alkaloid is abundant, is the Main Resources that extracts ephedrine.Relieving asthma, antitussive, removes expectorant, diaphoresis, and diuresis, antiinflammatory, antipyretic, excited maincenter.
Rhizoma Zingiberis: this product is the dry rhizome of zingiber ZingiberofficinaleRosc..Excavate winter, removes fibrous root and silt, dries or cold drying.Take advantage of that fresh slices is dried or cold drying person is called " dried ginger slice ".[nature and flavor] are pungent, hot.[return through] returns spleen, stomach, kidney, the heart, lung meridian.[function cures mainly] Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, cold extremities faint pulse, and phlegm retention is breathed with cough.
Another aspect of the present invention has been to provide the preparation method of the active component of Chinese medicine composition of the present invention, and the method is the ethanol extraction that adopts water extraction or 40-80% concentration expressed in percentage by volume.Concrete preparation method is as follows:
Scheme one: get all medical materials, extracting in water 2-3 time, each amount of water is equivalent to 6-12 times of medical material gross weight, each extraction time is 1-3 hour, and merge extractive liquid, filters, the clear paste that when filtrate is concentrated into 70-80 ℃, relative density is 1.10-1.25, obtains described active component.
Scheme two: get all medical materials, extracting in water 2-3 time, each amount of water is equivalent to 6-12 times of medical material gross weight, each extraction time is 1-3 hour, merge extractive liquid,, filters the clear paste that when filtrate is concentrated into 70-80 ℃, relative density is 1.05-1.20, add ethanol, making containing alcohol amount is 40-70%, and standing 12-24 hour filters, the extractum that when filtrate is concentrated into 70-80 ℃, relative density is 1.10-1.25, obtains described active component.
Scheme three: get all medical materials, use 40-80% alcohol reflux 2-3 time, the 4-10 that each ethanol consumption is medical material total amount doubly, extraction time is 1-3 hour, and merge extractive liquid, filters, the extractum that when filtrate is concentrated into 60-80 ℃, relative density is 1.10-1.25, obtains described active component.
The Chinese medicine composition for the treatment of infantile asthma of the present invention, can coordinate with pharmaceutically acceptable carrier, makes various common dosage forms, as tablet, granule, capsule, syrup, mixture etc.
Pharmaceutically acceptable carrier of the present invention includes but not limited to following:
Diluent: starch, Icing Sugar, lactose, dextrin, microcrystalline Cellulose, inorganic salt, sugar alcohols etc.
Wetting agent and binding agent: purified water, ethanol, gelatin, Polyethylene Glycol, cellulose derivative etc.
Disintegrating agent: starch, carboxymethyl starch sodium, cellulose derivative, polyvinylpolypyrrolidone etc.
Lubricant: magnesium stearate, micropowder silica gel, Pulvis Talci, Polyethylene Glycol etc.
Cosolvent: water, ethanol, glycerol, propylene glycol, liquid Paraffin, plant wet goods.
Correctives: sucrose, monosaccharide, aromatic etc.
Antiseptic: benzoic acid, sorbic acid, methyl ester, ethyl ester, propyl ester etc.
Method 1: tablet
Get scheme one to one of scheme three gained active component, add tablet to commonly use adjuvant, production method is prepared into tablet of the present invention routinely.
The conventional adjuvant of above-mentioned tablet comprises one of diluent, wetting agent, binding agent, disintegrating agent, lubricant or whole.
Method 2: granule
Get scheme one to one of scheme three gained active component, add granule to commonly use adjuvant, production method is prepared into granule of the present invention routinely.
The conventional adjuvant of above-mentioned granule comprises one of diluent, wetting agent, binding agent, disintegrating agent or whole.
Method 3: capsule
Get scheme one to one of scheme three gained active component, add capsule to commonly use adjuvant, production method is prepared into capsule of the present invention routinely.
The conventional adjuvant of above-mentioned capsule comprises one of diluent, wetting agent, binding agent, disintegrating agent, lubricant or whole.
Method 4: syrup
Get scheme one to one of scheme three gained active component, add syrup to commonly use adjuvant, production method is prepared into syrup of the present invention routinely.
The conventional adjuvant of above-mentioned syrup comprises one of correctives, antiseptic, cosolvent or whole.
Method 5: mixture
Get scheme one to one of scheme three gained active component, add mixture to commonly use adjuvant, production method is prepared into mixture of the present invention routinely.
The conventional adjuvant of above-mentioned mixture comprises one of correctives, antiseptic or whole.
Technical solution of the present invention meets the mechanism of tcm treatment according to syndrome differentiation, bases oneself upon the origin of disease, reasonable recipe science.
A kind of Chinese medicine composition for the treatment of infantile asthma provided by the invention has the following advantages:
1, the Chinese medicine composition for the treatment of infantile asthma provided by the invention to yang deficiency infantile asthma can warming for resolving cold-phlegm, antiasthmatic-antitussive, the total effective rate of clinical use treatment infantile asthma is 89%.
2, Chinese medicine composition composition formula of the present invention is rationally innovated, and production cost is low, technique is simple.
The specific embodiment
Below by embodiment, further illustrate the present invention.It should be understood that embodiments of the invention are for the present invention rather than limitation of the present invention are described.The simple modifications that essence according to the present invention is carried out the present invention all belongs to the scope of protection of present invention.
Embodiment 1 syrup
Get Radix Codonopsis 30g, Pericarpium Citri Reticulatae 20g, Radix Asteris 20g, Poria 20g, Ramulus Cinnamomi 10g, Herba Ephedrae 10g, Herba Asari 8g, Rhizoma Zingiberis 8g.By above-mentioned whole medical materials, extracting in water 2 times, twice amount of water is respectively 10 times, 8 times of medical material gross weight, and the extracted twice time is respectively 2 hours, 1 hour, and merge extractive liquid, filters the extractum that when filtrate is concentrated into 80 ℃, relative density is 1.10.In extractum, add syrup adjuvant sucrose, sorbic acid, water to stir, make syrup.
Embodiment 2 tablets
Get Radix Codonopsis 20g, Pericarpium Citri Reticulatae 20g, Radix Asteris 20g, Poria 10g, Ramulus Cinnamomi 5g, Herba Ephedrae 5g, Herba Asari 5g, Rhizoma Zingiberis 5g.By above-mentioned whole medical materials, with 40% alcohol reflux 3 times, each ethanol consumption is respectively 10 times, 8 times, 4 times of medical material total amount, 3 hours, 2 hours, 1 hour respectively extraction time, merge extractive liquid,, filters, the extractum that when filtrate concentrates 60 ℃, relative density is 1.25, add supplementary product starch, ethanol, Pulvis Talci, make tablet.
Embodiment 3 mixture
Get Radix Codonopsis 40g, Pericarpium Citri Reticulatae 30g, Radix Asteris 30g, Poria 30g, Ramulus Cinnamomi 15g, Herba Ephedrae 15g, Herba Asari 10g, Rhizoma Zingiberis 10g.By above-mentioned whole medical materials, extracting in water 3 times, three amount of water are equivalent to respectively 12 times, 8 times, 6 times of medical material gross weight, 3 hours, 2 hours, 1 hour respectively each extraction time, merge extractive liquid,, filter, the clear paste that when filtrate is concentrated into 70 ℃, relative density is 1.20, adds ethanol, and making containing alcohol amount is 40%, standing 24 hours, filter, the extractum that when filtrate is concentrated into filtrate and is concentrated into 70 ℃, relative density is 1.10, adding purified water ad pond om is 3 times of medical material gross weight, fill, obtains mixture of the present invention.
Add mixture adjuvant sucrose, ethyl ester, water, sorbic acid to stir, make mixture.
Embodiment 4 tablets
Get Radix Codonopsis 25g, Pericarpium Citri Reticulatae 15g, Radix Asteris 25g, Poria 15g, Ramulus Cinnamomi 8g, Herba Ephedrae 8g, Herba Asari 6g, Rhizoma Zingiberis 6g.By above-mentioned whole medical materials alcohol reflux 2 times, each concentration of alcohol is respectively 80%, 60%, each ethanol consumption is respectively 10 times, 8 times of medical material total amount, extraction time is respectively 4 hours, 3 hours, merge extractive liquid,, filters the extractum that when filtrate is concentrated into 80 ℃, relative density is 1.10, add supplementary product starch, ethanol, Pulvis Talci, make tablet.
Embodiment 5 capsules
Get Radix Codonopsis 35g, Pericarpium Citri Reticulatae 15g, Radix Asteris 15g, Poria 15g, Ramulus Cinnamomi 12g, Herba Ephedrae 12g, Herba Asari 9g, Rhizoma Zingiberis 9g.By above-mentioned whole medical materials, extracting in water 3 times, three amount of water are respectively 12 times, 8 times, 6 times of medical material gross weight, three extraction times are respectively 3 hours, 2 hours, 1 hour, merge extractive liquid,, filters the clear paste that when filtrate is concentrated into 70 ℃, relative density is 1.25, add supplementary product starch, ethanol, dextrin, magnesium stearate, incapsulate shell, make capsule.
Embodiment 6 granules
Get Radix Codonopsis 20g, Pericarpium Citri Reticulatae 25g, Radix Asteris 25g, Poria 20g, Ramulus Cinnamomi 5g, Herba Ephedrae 12g, Herba Asari 9g, Rhizoma Zingiberis 9g.By above-mentioned whole medical materials, extracting in water 2 times, each amount of water is equivalent to respectively 12 times, 10 times of medical material gross weight, each extraction time is respectively 3 hours, 2 hours, and merge extractive liquid, filters, filtrate is concentrated into the clear paste that at 80 ℃, relative density is 1.05, add ethanol, making containing alcohol amount is 70%, standing 12 hours, filter, the extractum that when filtrate is concentrated into 70 ℃, relative density is 1.25, adds adjuvant Icing Sugar, starch, dextrin, ethanol, makes granule.
Embodiment 7 powder
Take Radix Codonopsis 30g, Pericarpium Citri Reticulatae 20g, Radix Asteris 20g, Poria 20g, Ramulus Cinnamomi 10g, Herba Ephedrae 10g, Herba Asari 8g, Rhizoma Zingiberis 8g.Medical material cleans, pulverizes, and crosses 80-100 mesh sieve, obtains powder of the present invention.
Embodiment 8
The granule that the embodiment of the present invention 6 is prepared, gives infantile asthma patient oral, and each 1 bag, every day 3 times, clinical data is in Table 1:
Table 1 clinical data
Disorder class | Disease number of cases | The disease time | Treatment time | Efficiently individual quantity | Total effective rate |
Infantile asthma | 100 people | 7-30 days | 3-7 day | 88 people | 88% |
Embodiment 9
Zheng, 5 years old, cough with asthma first quarter moon did not take a favorable turn, rale asthma, cold limbs, tongue is white.Take the embodiment of the present invention 1 syrup after 2 days, sputum obviously reduces, and cough disappearance afterwards in 5 days, is judged to recovery from illness.
Although, above used general explanation, the specific embodiment and test, the present invention is described in detail, on basis of the present invention, can make some modifications or improvements it, and this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.
Claims (8)
1. treat a Chinese medicine composition for infantile asthma, it is characterized in that it is to be prepared from by the raw material that comprises following weight portion: Radix Codonopsis 20-40 part, Pericarpium Citri Reticulatae 20-30 part, Radix Asteris 20-30 part, Poria 10-30 part, Ramulus Cinnamomi 5-15 part, Herba Ephedrae 5-15 part, Herba Asari 5-10 part, Rhizoma Zingiberis 5-10 part.
2. the Chinese medicine composition for the treatment of infantile asthma as claimed in claim 1, is characterized in that it is to be prepared from by the raw material that comprises following weight portion: Radix Codonopsis 25-35 part, Pericarpium Citri Reticulatae 15-25 part, Radix Asteris 25-25 part, Poria 15-25 part, Ramulus Cinnamomi 8-12 part, Herba Ephedrae 8-12 part, Herba Asari 6-9 part, Rhizoma Zingiberis 6-9 part.
3. the Chinese medicine composition for the treatment of infantile asthma as claimed in claim 1, is characterized in that it is to be prepared from by the raw material that comprises following weight portion: 30 parts of Radix Codonopsis, 20 parts of Pericarpium Citri Reticulataes, 20 parts of Radix Asteriss, 20 parts, Poria, 10 parts of Ramulus Cinnamomi, 10 parts, Herba Ephedrae, 8 parts of Herba Asaris, 8 parts of Rhizoma Zingiberiss.
4. the Chinese medicine composition as described in claim 1-3 any one, the active component that it is characterized in that it is to adopt the ethanol extraction of water extraction or 40-80% concentration expressed in percentage by volume to be prepared from.
5. Chinese medicine composition as claimed in claim 4, the active component that it is characterized in that it is prepared from by the following method: get all medical materials, extracting in water 2-3 time, each amount of water is equivalent to 6-12 times of medical material gross weight, each extraction time is 1-3 hour, and merge extractive liquid, filters, the clear paste that when filtrate is concentrated into 70-80 ℃, relative density is 1.10-1.25, obtains described active component.
6. Chinese medicine composition as claimed in claim 4, the active component that it is characterized in that it is prepared from by the following method: get all medical materials, extracting in water 2-3 time, each amount of water is equivalent to 6-12 times of medical material gross weight, each extraction time is 1-3 hour, merge extractive liquid,, filter, the clear paste that when filtrate is concentrated into 70-80 ℃, relative density is 1.05-1.20, adds ethanol, and making containing alcohol amount is 40-70%, standing 12-24 hour, filter, the extractum that when filtrate is concentrated into 70-80 ℃, relative density is 1.10-1.25, obtains described active component.
7. Chinese medicine composition as claimed in claim 4, the active component that it is characterized in that it is prepared from by the following method: get all medical materials, with 40-80% alcohol reflux 2-3 time, the 4-10 that each ethanol consumption is medical material total amount doubly, extraction time is 1-3 hour, and merge extractive liquid, filters, the extractum that when filtrate is concentrated into 60-80 ℃, relative density is 1.10-1.25, obtains described active component.
8. treat a Chinese medicine composition for infantile asthma, comprise acceptable carrier in the Chinese medicine composition for the treatment of infantile asthma of any one in claim 1-3 and pharmaceuticals industry.
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CN104688903A (en) * | 2015-03-31 | 2015-06-10 | 佘延英 | Medicine for treating children cough |
CN106039056A (en) * | 2016-06-24 | 2016-10-26 | 王立丽 | Medicine composition for treating infantile cough and asthma |
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CN1312103A (en) * | 2001-02-23 | 2001-09-12 | 邓万发 | Chinese medicine for treating dyspneic cough effectively |
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CN1312103A (en) * | 2001-02-23 | 2001-09-12 | 邓万发 | Chinese medicine for treating dyspneic cough effectively |
Non-Patent Citations (1)
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104688903A (en) * | 2015-03-31 | 2015-06-10 | 佘延英 | Medicine for treating children cough |
CN106039056A (en) * | 2016-06-24 | 2016-10-26 | 王立丽 | Medicine composition for treating infantile cough and asthma |
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Application publication date: 20140416 |