CN103720876A - Traditional Chinese medicinal composition for treating infantile diarrhea and preparation method thereof - Google Patents
Traditional Chinese medicinal composition for treating infantile diarrhea and preparation method thereof Download PDFInfo
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- CN103720876A CN103720876A CN201310732415.3A CN201310732415A CN103720876A CN 103720876 A CN103720876 A CN 103720876A CN 201310732415 A CN201310732415 A CN 201310732415A CN 103720876 A CN103720876 A CN 103720876A
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Abstract
The invention discloses a traditional Chinese medicinal composition for treating infantile diarrhea and a preparation method thereof. The composition is prepared by using radix codonopsis, agastache rugosus, poria, schisandra chinensis, netmeg, endothelium corneum gigeriae galli and roasted liquorice as raw materials. The invention also provides the preparation method of the traditional Chinese medicinal composition for treating infantile diarrhea. The composition can be used for tonifying spleen and kidney, and relieving diarrhea with astringents, and has a remarkable treatment effect for infantile diarrhea.
Description
Technical field
The present invention relates to pharmaceutical sanitary field, be specifically related to Chinese medicine composition of a kind of children's's for the treatment of diarrhea and preparation method thereof.
Background technology
Infantile diarrhea, has another name called infantile dyspepsia, is a kind of acute functional gastrointestinal disorder of infantile period, take and suffer from diarrhoea, vomit as main syndrome, with summer and autumn sickness rate the highest.Primary disease paathogenic factor is divided into three aspects:: body constitution, infection and digestive functional disturbance.Clinical main manifestations is that times of defecation increases, passage of loose stools and Electrolyte imbalance.Primary disease treatment is proper, respond well, but not in time treatment so that can jeopardize children's's life while there is serious Electrolyte imbalance.
Children's's diarrhea mainly occurs in infant, its endogenous cause of ill feature:
(1) baby's gastrointestinal development is not mature enough, and the activity of enzyme is lower, but nutritional need is relatively many, and gastrointestinal tract burden is heavy.
(2) cradle nerve, endocrine, blood circulation and liver, renal function are grown equal immaturity, and regulative mechanism is poor.
(3) also imperfection of infant immunization function.Serum escherichia coli antibody titer is minimum to 2 one full year of life to come into being, and height edges up later.Thereby infant is easily suffered from escherichia coli enteritis.In breast milk, escherichia coli antibody titer is high, and particularly just Ruzhong Escherichia coli secretory IgA is high, so the less morbidity of breast-feeding infant is ill also lighter.In like manner young infant rotavirus antibody is low, and when same collective is popular, young infant is fallen ill many.
(4) distribution of baby's body fluid is different with adult, and extracellular fluid accounting example is higher, and water metabolism is vigorous, and regulatory function is poor again, and body fluid, electrolyte disturbance more easily occur.Baby easily suffers from rickets and malnutrition, easily causes digestive functional disturbance, and now intestinal secretion type IgA is not enough, easily what delay after diarrhoea.
Common method for the treatment of:
1. dietetic therapy
Light disease is reduced milk amount, and generation is with rice water, sugar-salt-water etc.; Serious symptom is answered fasting 8～24 hours, and vein fluid infusion.
2. fluid therapy
(1) oral medication is applicable to mild dehydration or vomits not severe one.Amount infused, by 100 milliliters of/day calculating of per kilogram of body weight, divides and takes several times.
(2) vein Clysis is for moderate, severe dehydration.
3. infection control
For the cause of disease, select antibacterials.
4. symptomatic treatment
Diarrhoea can oral 1 bismuth subcarbonate or light acid albumin.Aid digestion can oral Pepsin Mixture, or polyzyme tablets.According to state of an illness anti symptom treatment.
Summary of the invention
The Chinese medicine composition that the object of this invention is to provide a kind of children's's for the treatment of diarrhea;
Another object of the present invention is to provide a kind of Chinese medicine composition preparation method of the children's's for the treatment of diarrhea.
The object of the invention is to realize by following technical scheme:
The Chinese medicine composition for the treatment of children's diarrhea of the present invention is to be prepared from by the raw material containing following weight portion:
Radix Codonopsis 10-30 part, Herba Pogostemonis 5-15 part, Poria 5-15 part, Fructus Schisandrae Chinensis 5-15 part, Semen Myristicae 3-7 part, Endothelium Corneum Gigeriae Galli 3-7 part, Radix Glycyrrhizae Preparata 3-7 part.
Preferably, be to be prepared from by the raw material containing following weight portion:
Radix Codonopsis 15-25 part, Herba Pogostemonis 8-12 part, Poria 8-12 part, Fructus Schisandrae Chinensis 8-12 part, Semen Myristicae 4-6 part, Endothelium Corneum Gigeriae Galli 4-6 part, Radix Glycyrrhizae Preparata 4-6 part.
More preferably, be to be prepared from by the raw material containing following weight portion:
20 parts of Radix Codonopsis, 10 parts of Herba Pogostemoniss, 10 parts, Poria, 10 parts of Fructus Schisandrae Chinensis, 5 parts of Semen Myristicaes, 5 parts of Endothelium Corneum Gigeriae Galli, 5 parts of Radix Glycyrrhizae Preparatas.
Below crude drug source of the present invention:
Radix Codonopsis: this product is Campanulaceae Radix Codonopsis Codonopsispilosula(Franch.) Nannf., element flower Radix Codonopsis (RADIX CODONOPSIS PILOSULAE from Northwest of China) CodonopsispilosulaNannf.var.modesta(Nannf.) dry root of L.T.Shen or radix codonpsis tangshen CodonopsistangshenOliv..Excavate autumn, cleans, and dries.[nature and flavor] are sweet, flat.[return through] returns spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Herba Pogostemonis: be the herb of labiate Herba Pogostemonis or Herba Pogostemonis.[nature and flavor] are pungent, tepor.[return through] enters lung, spleen, stomach warp.[function cures mainly] fast gas, and in, ward off dirty, damp eliminating.The heat-damp in summer that cures cold, cold and heat, headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis.
Poria is the dry sclerotia of On Polyporaceae Poria Poriacocos (Schw.) Wolf.Record in one the 166th page of < < Chinese Pharmacopoeia > > version in 2005.[nature and flavor] are sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.
Fructus Schisandrae Chinensis: Magnoliacea plant schisandra chinensis Schisandra chinensls(Turcz) Baill, call profound and, meeting and, five Fructus Armeniacae Mumes, Fructus Zanthoxyli Plansipini, strong taste, the five tastes etc.Fructus Schisandrae Chinensis divides Radix Schisandrae Bicoloris and Fructus Schisandrae Sphenantherae.Nature and flavor: temperature, acid, sweet.Gui Jing: return lung, the heart, kidney channel.Astringe the lung, nourishing kidney, promotes the production of body fluid, and receives antiperspirant, arresting seminal emission.Control the deficiency of the lung and breath with cough, xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.
Semen Myristicae: dry kernel or the aril of Myristicaceae Nutmeg Vegetable meat Fructus Amomi Rotundus Myristica fragrans Houtt..Astringent medicinal; Drugs for dispelling internal cold; Qi-activating drug.[meridian distribution of property and flavor] is pungent; Bitter; Temperature.Return spleen; Stomach; Large intestine channel.[effect] warming middle-JIAO astringing intestine to stop diarrhea; Promote qi circulation digestion promoting.For diarrhea of deficiency type; Cold-dysentery; Abdominal distention; Lack of appetite vomiting; Dyspepsia does not disappear.
Endothelium Corneum Gigeriae Galli: this product is the dry inner wall of sandbag of the chicken GallusgallusdomesticusBrisson of Phasianidae animal man.Kill after chicken, take out chicken gizzard, peel immediately while hot inwall (first do not wash with water, otherwise difficulty being peeled off and easily fragmentation), cleaning, drying.[nature and flavor] are sweet, flat.[return through] returns spleen, stomach, small intestinal, urinary bladder channel.[function cures mainly] invigorating the stomach and promoting digestion, arresting seminal emission.For food stagnation, do not disappear, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission.
Radix Glycyrrhizae Preparata: the Preparation process product that this product is Radix Glycyrrhizae.Radix Glycyrrhizae is the dry root of the liquorice root GlycyrrhizauralensisFisch. of section, Glycyrrhiza inflata Bat. GlycyrrhizainflataBat. or Glycyrrhiza glabra L. GlycyrrhizaglabraL..Spring, Qiu Erji excavate, and remove fibrous root, dry.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] spleen reinforcing stomach function regulating, Yiqi and vein recovery.For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.
Another aspect of the present invention has been to provide the preparation method of the active component of Chinese medicine composition of the present invention, and the method is the ethanol extraction that adopts water extraction or 40-80% concentration expressed in percentage by volume.Concrete preparation method is as follows:
Scheme one: get all medical materials, extracting in water 2-3 time, each amount of water is equivalent to 6-12 times of medical material gross weight, each extraction time is 1-3 hour, and merge extractive liquid, filters, the clear paste that when filtrate is concentrated into 70-80 ℃, relative density is 1.10-1.25, obtains described active component.
Scheme two: get all medical materials, extracting in water 2-3 time, each amount of water is equivalent to 6-12 times of medical material gross weight, each extraction time is 1-3 hour, merge extractive liquid,, filters the clear paste that when filtrate is concentrated into 70-80 ℃, relative density is 1.05-1.20, add ethanol, making containing alcohol amount is 40-70%, and standing 12-24 hour filters, the extractum that when filtrate is concentrated into 70-80 ℃, relative density is 1.10-1.25, obtains described active component.
Scheme three: get all medical materials, use 40-80% alcohol reflux 2-3 time, the 4-10 that each ethanol consumption is medical material total amount doubly, extraction time is 1-3 hour, and merge extractive liquid, filters, the extractum that when filtrate is concentrated into 60-80 ℃, relative density is 1.10-1.25, obtains described active component.
The Chinese medicine composition for the treatment of children's diarrhea of the present invention, can coordinate with pharmaceutically acceptable carrier, makes various common dosage forms, as tablet, granule, capsule, syrup, mixture etc.
Pharmaceutically acceptable carrier of the present invention includes but not limited to following:
Diluent: starch, Icing Sugar, lactose, dextrin, microcrystalline Cellulose, inorganic salt, sugar alcohols etc.
Wetting agent and binding agent: purified water, ethanol, gelatin, Polyethylene Glycol, cellulose derivative etc.
Disintegrating agent: starch, carboxymethyl starch sodium, cellulose derivative, polyvinylpolypyrrolidone etc.
Lubricant: magnesium stearate, micropowder silica gel, Pulvis Talci, Polyethylene Glycol etc.
Cosolvent: water, ethanol, glycerol, propylene glycol, liquid Paraffin, plant wet goods.
Correctives: sucrose, monosaccharide, aromatic etc.
Antiseptic: benzoic acid, sorbic acid, methyl ester, ethyl ester, propyl ester etc.
Method 1: tablet
Get scheme one to one of scheme three gained active component, add tablet to commonly use adjuvant, production method is prepared into tablet of the present invention routinely.
The conventional adjuvant of above-mentioned tablet comprises one of diluent, wetting agent, binding agent, disintegrating agent, lubricant or whole.
Method 2: granule
Get scheme one to one of scheme three gained active component, add granule to commonly use adjuvant, production method is prepared into granule of the present invention routinely.
The conventional adjuvant of above-mentioned granule comprises one of diluent, wetting agent, binding agent, disintegrating agent or whole.
Method 3: capsule
Get scheme one to one of scheme three gained active component, add capsule to commonly use adjuvant, production method is prepared into capsule of the present invention routinely.
The conventional adjuvant of above-mentioned capsule comprises one of diluent, wetting agent, binding agent, disintegrating agent, lubricant or whole.
Method 4: syrup
Get scheme one to one of scheme three gained active component, add syrup to commonly use adjuvant, production method is prepared into syrup of the present invention routinely.
The conventional adjuvant of above-mentioned syrup comprises one of correctives, antiseptic, cosolvent or whole.
Method 5: mixture
Get scheme one to one of scheme three gained active component, add mixture to commonly use adjuvant, production method is prepared into mixture of the present invention routinely.
The conventional adjuvant of above-mentioned mixture comprises one of correctives, antiseptic or whole.
Technical solution of the present invention meets the mechanism of tcm treatment according to syndrome differentiation, bases oneself upon the origin of disease, reasonable recipe science.
The Chinese medicine composition of a kind of children's's for the treatment of diarrhea provided by the invention has the following advantages:
1, the Chinese medicine composition for the treatment of provided by the invention children's diarrhea to children's's diarrhea due to cold pathogen can warming and recuperating the spleen and kidney, relieving diarrhea with astringents, the total effective rate of clinical use treatment children's diarrhea is 85%.
2, Chinese medicine composition composition formula of the present invention is rationally innovated, and production cost is low, technique is simple.
The specific embodiment
Below by embodiment, further illustrate the present invention.It should be understood that embodiments of the invention are for the present invention rather than limitation of the present invention are described.The simple modifications that essence according to the present invention is carried out the present invention all belongs to the scope of protection of present invention.
Embodiment 1 syrup
Get Radix Codonopsis 20g, Herba Pogostemonis 10g, Poria 10g, Fructus Schisandrae Chinensis 10g, Semen Myristicae 5g, Endothelium Corneum Gigeriae Galli 5g, Radix Glycyrrhizae Preparata 5g.By above-mentioned whole medical materials, extracting in water 2 times, twice amount of water is respectively 10 times, 8 times of medical material gross weight, and the extracted twice time is respectively 2 hours, 1 hour, and merge extractive liquid, filters the extractum that when filtrate is concentrated into 80 ℃, relative density is 1.10.In extractum, add syrup adjuvant sucrose, sorbic acid, water to stir, make syrup.
Embodiment 2 tablets
Get Radix Codonopsis 10g, Herba Pogostemonis 5g, Poria 5g, Fructus Schisandrae Chinensis 5g, Semen Myristicae 3g, Endothelium Corneum Gigeriae Galli 3g, Radix Glycyrrhizae Preparata 3g.By above-mentioned whole medical materials, with 40% alcohol reflux 3 times, each ethanol consumption is respectively 10 times, 8 times, 4 times of medical material total amount, 3 hours, 2 hours, 1 hour respectively extraction time, merge extractive liquid,, filters, the extractum that when filtrate concentrates 60 ℃, relative density is 1.25, add supplementary product starch, ethanol, Pulvis Talci, make tablet.
Embodiment 3 mixture
Get Radix Codonopsis 30g, Herba Pogostemonis 15g, Poria 15g, Fructus Schisandrae Chinensis 15g, Semen Myristicae 7g, Endothelium Corneum Gigeriae Galli 7g, Radix Glycyrrhizae Preparata 7g.By above-mentioned whole medical materials, extracting in water 3 times, three amount of water are equivalent to respectively 12 times, 8 times, 6 times of medical material gross weight, 3 hours, 2 hours, 1 hour respectively each extraction time, merge extractive liquid,, filter, the clear paste that when filtrate is concentrated into 70 ℃, relative density is 1.20, adds ethanol, and making containing alcohol amount is 40%, standing 24 hours, filter, the extractum that when filtrate is concentrated into filtrate and is concentrated into 70 ℃, relative density is 1.10, adding purified water ad pond om is 3 times of medical material gross weight, fill, obtains mixture of the present invention.
Add mixture adjuvant sucrose, ethyl ester, water, sorbic acid to stir, make mixture.
Embodiment 4 tablets
Get Radix Codonopsis 15g, Herba Pogostemonis 8g, Poria 8g, Fructus Schisandrae Chinensis 8g, Semen Myristicae 4g, Endothelium Corneum Gigeriae Galli 4g, Radix Glycyrrhizae Preparata 4g.By above-mentioned whole medical materials alcohol reflux 2 times, each concentration of alcohol is respectively 80%, 60%, each ethanol consumption is respectively 10 times, 8 times of medical material total amount, extraction time is respectively 4 hours, 3 hours, merge extractive liquid,, filters the extractum that when filtrate is concentrated into 80 ℃, relative density is 1.10, add supplementary product starch, ethanol, Pulvis Talci, make tablet.
Embodiment 5 capsules
Get Radix Codonopsis 25g, Herba Pogostemonis 12g, Poria 12g, Fructus Schisandrae Chinensis 12g, Semen Myristicae 6g, Endothelium Corneum Gigeriae Galli 6g, Radix Glycyrrhizae Preparata 6g.By above-mentioned whole medical materials, extracting in water 3 times, three amount of water are respectively 12 times, 8 times, 6 times of medical material gross weight, three extraction times are respectively 3 hours, 2 hours, 1 hour, merge extractive liquid,, filters the clear paste that when filtrate is concentrated into 70 ℃, relative density is 1.25, add supplementary product starch, ethanol, dextrin, magnesium stearate, incapsulate shell, make capsule.
Embodiment 6 granules
Get Radix Codonopsis 10g, Herba Pogostemonis 8g, Poria 10g, Fructus Schisandrae Chinensis 15g, Semen Myristicae 6g, Endothelium Corneum Gigeriae Galli 5g, Radix Glycyrrhizae Preparata 5g.By above-mentioned whole medical materials, extracting in water 2 times, each amount of water is equivalent to respectively 12 times, 10 times of medical material gross weight, each extraction time is respectively 3 hours, 2 hours, and merge extractive liquid, filters, filtrate is concentrated into the clear paste that at 80 ℃, relative density is 1.05, add ethanol, making containing alcohol amount is 70%, standing 12 hours, filter, the extractum that when filtrate is concentrated into 70 ℃, relative density is 1.25, adds adjuvant Icing Sugar, starch, dextrin, ethanol, makes granule.
Embodiment 7 powder
Take Radix Codonopsis 20g, Herba Pogostemonis 10g, Poria 10g, Fructus Schisandrae Chinensis 10g, Semen Myristicae 5g, Endothelium Corneum Gigeriae Galli 5g, Radix Glycyrrhizae Preparata 5g.Medical material cleans, pulverizes, and crosses 80-100 mesh sieve, obtains powder of the present invention.
Embodiment 8
The granule that the embodiment of the present invention 6 is prepared, gives children's's diarrhea patient oral, and each 1 bag, every day 3 times, clinical data is in Table 1:
Table 1 clinical data
| Disorder class | Disease number of cases | The disease time | Treatment time | Efficiently individual quantity | Total effective rate |
| Children's's diarrhea | 100 people | 3-15 days | 3-7 day | 85 people | 85% |
Embodiment 9
Zheng, 4 years old, diarrhea 7 days, suffered from diarrhoea more than ten every day, extremities being not warm, pale complexion, pale tongue.Take the embodiment of the present invention 1 syrup after 2 days, diarrhoea is reduced to every day 3-4 time, serve on after 7 days, and stool is shaped, and all diseases are fully recovered.
Although, above used general explanation, the specific embodiment and test, the present invention is described in detail, on basis of the present invention, can make some modifications or improvements it, and this will be apparent to those skilled in the art.Therefore, these modifications or improvements, all belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (8)
1. treat a Chinese medicine composition for children's's diarrhea, it is characterized in that it is to be prepared from by the raw material that comprises following weight portion: Radix Codonopsis 10-30 part, Herba Pogostemonis 5-15 part, Poria 5-15 part, Fructus Schisandrae Chinensis 5-15 part, Semen Myristicae 3-7 part, Endothelium Corneum Gigeriae Galli 3-7 part, Radix Glycyrrhizae Preparata 3-7 part.
2. the Chinese medicine composition for the treatment of children's diarrhea as claimed in claim 1, is characterized in that it is to be prepared from by the raw material that comprises following weight portion: Radix Codonopsis 15-25 part, Herba Pogostemonis 8-12 part, Poria 8-12 part, Fructus Schisandrae Chinensis 8-12 part, Semen Myristicae 4-6 part, Endothelium Corneum Gigeriae Galli 4-6 part, Radix Glycyrrhizae Preparata 4-6 part.
3. the Chinese medicine composition for the treatment of children's diarrhea as claimed in claim 1, is characterized in that it is to be prepared from by the raw material that comprises following weight portion: 20 parts of Radix Codonopsis, 10 parts of Herba Pogostemoniss, 10 parts, Poria, 10 parts of Fructus Schisandrae Chinensis, 5 parts of Semen Myristicaes, 5 parts of Endothelium Corneum Gigeriae Galli, 5 parts of Radix Glycyrrhizae Preparatas.
4. the Chinese medicine composition as described in claim 1-3 any one, the active component that it is characterized in that it is to adopt the ethanol extraction of water extraction or 40-80% concentration expressed in percentage by volume to be prepared from.
5. Chinese medicine composition as claimed in claim 4, the active component that it is characterized in that it is prepared from by the following method: get all medical materials, extracting in water 2-3 time, each amount of water is equivalent to 6-12 times of medical material gross weight, each extraction time is 1-3 hour, and merge extractive liquid, filters, the clear paste that when filtrate is concentrated into 70-80 ℃, relative density is 1.10-1.25, obtains described active component.
6. Chinese medicine composition as claimed in claim 4, the active component that it is characterized in that it is prepared from by the following method: get all medical materials, extracting in water 2-3 time, each amount of water is equivalent to 6-12 times of medical material gross weight, each extraction time is 1-3 hour, merge extractive liquid,, filter, the clear paste that when filtrate is concentrated into 70-80 ℃, relative density is 1.05-1.20, adds ethanol, and making containing alcohol amount is 40-70%, standing 12-24 hour, filter, the extractum that when filtrate is concentrated into 70-80 ℃, relative density is 1.10-1.25, obtains described active component.
7. Chinese medicine composition as claimed in claim 4, the active component that it is characterized in that it is prepared from by the following method: get all medical materials, with 40-80% alcohol reflux 2-3 time, the 4-10 that each ethanol consumption is medical material total amount doubly, extraction time is 1-3 hour, and merge extractive liquid, filters, the extractum that when filtrate is concentrated into 60-80 ℃, relative density is 1.10-1.25, obtains described active component.
8. treat a Chinese medicine composition for children's's diarrhea, comprise acceptable carrier in the Chinese medicine composition for the treatment of children's diarrhea of any one in claim 1-3 and pharmaceuticals industry.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108404068A (en) * | 2017-02-09 | 2018-08-17 | 扬子江药业集团四川海蓉药业有限公司 | A kind of pharmaceutical composition and preparation method thereof for the treatment of and/or pre- anti-diarrhea |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103041330A (en) * | 2012-12-17 | 2013-04-17 | 青岛盛瀚色谱技术有限公司 | Traditional Chinese medicine composition for treating chronic diarrhoea |
| CN103041360A (en) * | 2013-01-16 | 2013-04-17 | 李郑生 | Oral liquid for treating functional diarrhea and irritable bowel syndrome |
| CN103394057A (en) * | 2013-07-24 | 2013-11-20 | 赵世明 | Traditional Chinese medicine composition for treating diarrhoea |
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2013
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103041330A (en) * | 2012-12-17 | 2013-04-17 | 青岛盛瀚色谱技术有限公司 | Traditional Chinese medicine composition for treating chronic diarrhoea |
| CN103041360A (en) * | 2013-01-16 | 2013-04-17 | 李郑生 | Oral liquid for treating functional diarrhea and irritable bowel syndrome |
| CN103394057A (en) * | 2013-07-24 | 2013-11-20 | 赵世明 | Traditional Chinese medicine composition for treating diarrhoea |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108404068A (en) * | 2017-02-09 | 2018-08-17 | 扬子江药业集团四川海蓉药业有限公司 | A kind of pharmaceutical composition and preparation method thereof for the treatment of and/or pre- anti-diarrhea |
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Application publication date: 20140416 |