CN101549003A - Anti-virus throat-clearing buccal tablets and preparation method thereof - Google Patents
Anti-virus throat-clearing buccal tablets and preparation method thereof Download PDFInfo
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- CN101549003A CN101549003A CNA2008101034194A CN200810103419A CN101549003A CN 101549003 A CN101549003 A CN 101549003A CN A2008101034194 A CNA2008101034194 A CN A2008101034194A CN 200810103419 A CN200810103419 A CN 200810103419A CN 101549003 A CN101549003 A CN 101549003A
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Abstract
The invention relates to anti-virus throat-clearing buccal tablets and a preparation method thereof, the product is prepared by the following pharmaceutical raw materials according to the proportioning by weight: 5-15 portions by weight of Indigowoad root, 5-15 portions by weight of honeysuckle flower, 1-15 portions by weight of Chinese caterpillar fungus and 0.01-1.0 portion by weight of peppermint camphor, and the buccal tablets are prepared by extraction, concentration, drying and the like. The buccal tablets have the efficacies of clearing heat, removing toxin, relieving sore throat, relieving swelling and enhancing body immunity and are used for preventing and treating acute and chronic pharyngitis, tonsillitis, oral inflammation, peculiar smell of oral cavity, throat discomfort and the like; furthermore, the product is a pure traditional Chinese medicine preparation, and thus being capable of safely taking medicine.
Description
Technical field
The present invention relates to a kind of buccal tablet and preparation method thereof, particularly relate to a kind of anti-virus throat-clearing buccal tablets and preparation method thereof, belong to technical field of Chinese medicines.
Background technology
Acute/chronic pharyngitis, tonsillitis, oral inflammation and halitosis, throat discomfort are common clinical disease, but because its paathogenic factor is indefinite, the general course of disease is shorter, clinical symptoms is lighter, and therefore clinical prescription on individual diagnosis rate is lower, does not still have epidemiology correlational study and report at present.
Throat and oral disease mostly are due to viral infection, the bacterial infection, and be relevant with environmental pollution, dietary habit and Physiological Psychology factor, and sickness rate is higher, brings certain influence for people's life.
Because the clinical symptoms of throat and oral disease is light, therefore, the related drugs that has prevention and treatment in the treatment field is less, as watermelon crystal buccal tablet, JINSANGZI HOUPIAN etc., has played the good curing effect at aspects such as treatment acute/chronic pharyngitis, tonsillitiss.
Along with improving constantly of living standard, people's health care consciousness is also in continuous lifting, pursuing good life, study and duty, to have become in the life institute essential, therefore, safety is taken in exploitation, and what be suitable for that the normal phase takes is used for prevention and treatment throat and oral inflammation, remove halitosis, alleviate the moistening and cleaning throat product of throat discomfort, market potential is huge, has a extensive future.
Summary of the invention
One of the object of the invention is to provide a kind of anti-virus throat-clearing buccal tablets, this product has heat-clearing and toxic substances removing, relieving sore throat and diminishing swelling, the effect of enhancing human body immunity power, be used for prevention and diseases such as treatment acute/chronic pharyngitis, tonsillitis, oral inflammation and halitosis, throat discomfort, be pure Chinese medicinal preparation, take safety.
Two of the object of the invention is to provide a kind of preparation method of anti-virus throat-clearing buccal tablets.
The present invention select for use have heat-clearing and toxic substances removing, the Radix Isatidis of removing heat from blood sore-throat relieving effect for the side in principal agent, be aided with Flos Lonicerae to strengthen the merit of its heat-clearing and toxic substances removing, with the human body immunity improving function, Mentholum has the effect of fragrant seasoning to assistant with Cordyceps, to strengthen its mouthfeel and moistening and cleaning throat effect.
Radix Isatidis contains tens of kinds of compositions such as indigo glycoside, cupreol, isatin, be clinical conventional Chinese medicine material, have analgesic, antibiotic, antivirus action, multiple gram positive bacteria, gram negative bacteria and virus are all had significant inhibitory effect, and have enhancing human body immunity power function.Clinically be mainly used in diseases such as treatment influenza, mumps, swelling throat carbuncle.
Flos Lonicerae has broad-spectrum antibacterial action, and various pathogens such as staphylococcus aureus, dysentery bacterium are all had stronger inhibitory action; Cariogenic bacteria (Streptococcus mutans) had inhibitory or killing effect preferably; Has tangible antiinflammatory refrigeration function; Multiple virus all there is inhibitory action, and immune system is had dual regulation.
Cordyceps mainly contains polysaccharide, aminoacid, polypeptide, nucleic acid, vitamin and flavone, Saponin constituents.Has pharmacological action widely.Cordyceps has strengthening the body resistance, the effect of human body immunity improving power, but invigorating the lung and benefiting vital QI again, resolving phlegm and relieving asthma, and resisting fatigue arranged, improve sleep, pharmacological action such as slow down aging and relieving neurasthenia.
A kind of anti-virus throat-clearing buccal tablets provided by the invention is to be made by following raw materials by weight proportions:
Radix Isatidis 5～15 weight portion Flos Loniceraes 5～15 weight portions
Cordyceps 1～15 weight portion Mentholum 0.01～1.0 weight portion
Further, on the basis that the above-mentioned raw materials medicine is formed, the weight proportion of its crude drug can be adopted as especially:
Radix Isatidis 8～12 weight portion Flos Loniceraes 8～12 weight portions
Cordyceps 3～10 weight portion Mentholums 0.05～0.5 weight portion
The present invention realizes by following preparation method
(1) get Radix Isatidis, be ground into coarse powder, add 8～12 times of water gagings and decoct 2～3 times, each 2～3 hours, decocting liquid filtered, and merging filtrate is evaporated to relative density and is 1.10～1.30 clear paste under 55～70 ℃ of conditions, standby;
(2) extracting honeysuckle, Cordyceps, fragmentation adds 10～14 times of water gagings warm macerating 2～4 times under 60～90 ℃ of conditions, each 2～6 hours, warm macerating liquid filtered, merging filtrate, under 55～70 ℃ of conditions, be evaporated to relative density and be 1.10～1.30 clear paste, standby;
(3) get above-mentioned clear paste, mix homogeneously, standby;
(4) get sweeting agent, aromatic and proper auxiliary materials, add in step (3) the gained clear paste, mix homogeneously, vacuum drying is ground into fine powder, gets dry extract, and is standby;
(5) get dry extract, use 85% alcohol granulation, drying, granulate gets granule, and is standby;
(6) get Mentholum, use anhydrous alcohol solution, evenly spray in the granule, add magnesium stearate, mix homogeneously;
(7) tabletting, packing, check promptly gets buccal tablet.
The used edulcorant of the present invention can select for use sucrose, aspartame, steviosin, mannitol etc. to can be used in the sweeting agent of food and medicine one or more.
The used aromatic of the present invention can be selected fruit essences such as Fructus Citri Limoniae essence, flavoring orange essence, apple essence for use or not select for use.
Below by specific embodiment preparation method of the present invention is described, example is based on the above-mentioned subject area of the present invention, but is not limited to following example.
Embodiment 1
(1) Radix Isatidis 100g is ground into coarse powder, adds 10 times of water gagings and decocts 2 hours, and decocting liquid filters; Medicinal residues add 10 times of water gagings and decocted 2 hours, and decocting liquid filters; Medicinal residues add 8 times of water gagings again and decocted 1 hour, and decocting liquid filters, and filtrate merges, and are evaporated to relative density and are 1.30 clear paste under 60 ℃ of conditions, and are standby;
(2) extracting honeysuckle 100g, Cordyceps 60g, fragmentation adds 14 times of water gagings warm macerating 6 hours under 60 ℃ of conditions, and warm macerating liquid filters; Medicinal residues add 12 times of water gagings warm macerating 4 hours under 60 ℃ of conditions, and warm macerating liquid filters; Medicinal residues added under 60 ℃ of conditions of 12 times of water gagings warm macerating 4 hours again, and warm macerating liquid filters; Merging filtrate is evaporated to relative density and is 1.30 clear paste under 55 ℃ of conditions, standby;
(3) get above-mentioned clear paste, mix homogeneously, standby;
(4) get sucrose 215g, steviosin 2.2g, be ground into fine powder, cross 100 mesh sieves, standby;
(5) get step (4) gained fine powder and dextrin 30g, add in step (3) the gained clear paste, mix homogeneously, vacuum drying is ground into fine powder, gets dry extract, and is standby;
(6) get dry extract, use 85% alcohol granulation, drying, granulate gets granule, and is standby;
(7) get Mentholum 1g, use anhydrous alcohol solution, evenly spray in the granule, add 0.4% magnesium stearate, mix homogeneously;
(8) tabletting, packing, check promptly gets buccal tablet.
Embodiment 2
(1) Radix Isatidis 120g is ground into coarse powder, adds 12 times of water gagings and decocts 2 hours, and decocting liquid filters; Medicinal residues add 10 times of water gagings and decocted 2 hours, and decocting liquid filters; Medicinal residues add 10 times of water gagings again and decocted 1 hour, and decocting liquid filters, and filtrate merges, and are evaporated to relative density and are 1.25 clear paste under 60 ℃ of conditions, and are standby;
(2) extracting honeysuckle 120g, Cordyceps 50g, fragmentation adds 12 times of water gagings warm macerating 6 hours under 60 ℃ of conditions, and warm macerating liquid filters; Medicinal residues add 12 times of water gagings warm macerating 6 hours under 60 ℃ of conditions, and warm macerating liquid filters; Medicinal residues added under 60 ℃ of conditions of 10 times of water gagings warm macerating 4 hours again, and warm macerating liquid filters; Merging filtrate is evaporated to relative density and is 1.25 clear paste under 55 ℃ of conditions, standby;
(3) get above-mentioned clear paste, mix homogeneously, standby;
(4) get aspartame 5.0g, Fructus Citri Limoniae essence 9.0g, be ground into fine powder, cross 100 mesh sieves, standby;
(5) get step (4) gained fine powder and dextrin 60g, add in step (3) the gained clear paste, mix homogeneously, vacuum drying is ground into fine powder, gets dry extract, and is standby;
(6) get dry extract, use 85% alcohol granulation, drying, granulate gets granule, and is standby;
(7) get Mentholum 1.2g, use anhydrous alcohol solution, evenly spray in the granule, add 0.4% magnesium stearate, mix homogeneously;
(8) suppress special-shaped sheet, packing, check promptly gets buccal tablet.
Claims (5)
1, a kind of anti-virus throat-clearing buccal tablets is characterized in that this buccal tablet is to be made by following raw materials by weight proportions:
Radix Isatidis 5～15 weight portion Flos Loniceraes 5～15 weight portions
Cordyceps 1～15 weight portion Mentholum 0.01～1.0 weight portion.
2, a kind of anti-virus throat-clearing buccal tablets as claimed in claim 1 is characterized in that this buccal tablet is to be made by following raw materials by weight proportions:
Radix Isatidis 8～12 weight portion Flos Loniceraes 8～12 weight portions
Cordyceps 3～10 weight portion Mentholums 0.05～0.5 weight portion.
3, the preparation method of a kind of anti-virus throat-clearing buccal tablets as claimed in claim 1 or 2 is as follows:
(1) get Radix Isatidis, be ground into coarse powder, add 8～12 times of water gagings and decoct 2～3 times, each 2～3 hours, decocting liquid filtered, and merging filtrate is evaporated to relative density and is 1.10～1.30 clear paste under 55～70 ℃ of conditions, standby;
(2) extracting honeysuckle, Cordyceps, fragmentation adds 10～14 times of water gagings warm macerating 2～4 times under 60～90 ℃ of conditions, each 2～6 hours, warm macerating liquid filtered, merging filtrate, under 55～70 ℃ of conditions, be evaporated to relative density and be 1.10～1.30 clear paste, standby;
(3) get above-mentioned clear paste, mix homogeneously, standby;
(4) get sweeting agent, aromatic and proper auxiliary materials, add in step (3) the gained clear paste, mix homogeneously, vacuum drying is ground into fine powder, gets dry extract, and is standby;
(5) get dry extract, use 85% alcohol granulation, drying, granulate gets granule, and is standby;
(6) get Mentholum, use anhydrous alcohol solution, evenly spray in the granule, add magnesium stearate, mix homogeneously;
(7) tabletting, packing, check promptly gets buccal tablet.
4, as described in the claim 3, the used edulcorant of the present invention can select for use sucrose, aspartame, steviosin, mannitol etc. to can be used in the sweeting agent of food and medicine one or more.
5, as described in the claim 3, the used aromatic of the present invention can be selected fruit essences such as Fructus Citri Limoniae essence, flavoring orange essence, apple essence for use or not select for use.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101034194A CN101549003A (en) | 2008-04-03 | 2008-04-03 | Anti-virus throat-clearing buccal tablets and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101034194A CN101549003A (en) | 2008-04-03 | 2008-04-03 | Anti-virus throat-clearing buccal tablets and preparation method thereof |
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| CN101549003A true CN101549003A (en) | 2009-10-07 |
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| CNA2008101034194A Pending CN101549003A (en) | 2008-04-03 | 2008-04-03 | Anti-virus throat-clearing buccal tablets and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103284318A (en) * | 2013-06-20 | 2013-09-11 | 中国烟草总公司山东省公司 | Sublingual cigarette and preparation method thereof |
| CN103301254A (en) * | 2013-06-27 | 2013-09-18 | 广西信业生物技术有限公司 | Antibacterial liquid used for nasopharyal meatus and preparation method thereof |
| CN103875852A (en) * | 2014-03-27 | 2014-06-25 | 青岛崂好人海洋生物技术有限公司 | Grateloupia filicina tea for treating pharyngitis |
| CN105124664A (en) * | 2015-07-25 | 2015-12-09 | 济南骄泰信息技术有限公司 | Apple juice relieving and protecting throat |
| CN107397877A (en) * | 2017-09-14 | 2017-11-28 | 郑磊 | The formula and its preparation technology of guttural tablets |
-
2008
- 2008-04-03 CN CNA2008101034194A patent/CN101549003A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103284318A (en) * | 2013-06-20 | 2013-09-11 | 中国烟草总公司山东省公司 | Sublingual cigarette and preparation method thereof |
| CN103284318B (en) * | 2013-06-20 | 2015-03-11 | 中国烟草总公司山东省公司 | Sublingual cigarette and preparation method thereof |
| CN103301254A (en) * | 2013-06-27 | 2013-09-18 | 广西信业生物技术有限公司 | Antibacterial liquid used for nasopharyal meatus and preparation method thereof |
| CN103301254B (en) * | 2013-06-27 | 2015-02-25 | 广西信业生物技术有限公司 | Antibacterial liquid used for nasopharyal meatus and preparation method thereof |
| CN103875852A (en) * | 2014-03-27 | 2014-06-25 | 青岛崂好人海洋生物技术有限公司 | Grateloupia filicina tea for treating pharyngitis |
| CN103875852B (en) * | 2014-03-27 | 2016-05-04 | 青岛崂好人海洋生物技术有限公司 | A kind of centipede algae tea for the treatment of pharyngitis |
| CN105124664A (en) * | 2015-07-25 | 2015-12-09 | 济南骄泰信息技术有限公司 | Apple juice relieving and protecting throat |
| CN107397877A (en) * | 2017-09-14 | 2017-11-28 | 郑磊 | The formula and its preparation technology of guttural tablets |
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| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20091007 |