CN101543293A - A health food with properties for intensifying human body immunity and supplementing mineral composition - Google Patents
A health food with properties for intensifying human body immunity and supplementing mineral composition Download PDFInfo
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- CN101543293A CN101543293A CN200910039183A CN200910039183A CN101543293A CN 101543293 A CN101543293 A CN 101543293A CN 200910039183 A CN200910039183 A CN 200910039183A CN 200910039183 A CN200910039183 A CN 200910039183A CN 101543293 A CN101543293 A CN 101543293A
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Abstract
The invention discloses a health food with properties for intensifying human body immunity and supplementing mineral composition, which comprises following components according to weight percentage of: 0.0 percent-60.0 percent of fructooligosaccharides; 0.0 percent-40.0 percent of taurine; 0.1 percent-30.0 percent of aloe extract; 0.0 percent-30.0 percent of royal jelly; 0.0 percent-30.0 percent of pollen; 0.0 percent-30.0 percent of vitamin C; 0.0 percent-30.0 percent of lysine; 0.0 percent-30.0 percent of alanine; 0.1 percent-30.0 percent of mineral composition mixture; 0.0 percent-95.0 percent of accessory. The health food of the invention is obtained through a scientific composition and reasonably collocation of each raw material with exact efficacy, thus intensifying human body immunity and improving absorption of mineral composition element in the meanwhile.
Description
Technical field
The present invention relates to a kind of health food, more particularly, the present invention relates to a kind of the have body immunity of enhancing and additional mineral matter health care foods.
Background technology
Immunity is the defense mechanism of human body self, is human body identification and any foreign matter of eliminating external intrusion, handles the ability of self cell and identification and the processing vivo mutations cell and the virus infected cell of old and feeble, damage, dead, sex change.Low when immunity of organisms, when immune system can not normally be brought into play protective effect, health was easy to by infection or cancer strickens such as bacterium, virus, fungies.Therefore, use various medicine and the health foods that strengthen immunologic function that have, treat and improve the low caused illness of immunity of organisms, have crucial meaning.In addition, between the mineral matter element in body immunity and the body inseparable getting in touch arranged, mineral matter element is not only the essential composition of immunocyte, and the also too busy to get away mineral matter element of secretion of various immune response process and antibody, complement.
At present, the health food of many enhancing immunity or additional mineral matter is arranged on the market, but it is rare to have the health food of these two kinds of effects simultaneously.In the health food that strengthens immunity, be most needs of health food of raw material with Chinese medicine by extraction process, the technology relative complex, consuming time long.And in the health food that replenishes mineral matter, most products are to replenish by amount singlely, do not consider that can mineral matter be absorbed by human body and utilize effectively, if a large amount of mineral matters that replenish can't be absorbed by the body and utilize, excessive mineral matter can be excreted by human body, causes resource and cost waste.
The present invention is on the basis of existing technology, and is by scientific composition that the raw material of each exact efficacy is reasonably combined, can promote the health food that mineral matter absorbs thereby provide a kind of when strengthening body immunity.
Summary of the invention
The object of the present invention is to provide a kind of the have body immunity of enhancing and additional mineral matter health care foods, pass through scientific composition, the raw material of each exact efficacy is reasonably combined, promote that when strengthening body immunity mineral matter element absorbs, make product efficacy show more outstandingly and reasonable.
Of the present invention have strengthen body immunity and additional mineral matter health care foods, comprise following component by weight percentage:
FOS 0.0%～60.0%; Taurine 0.0%～40.0%; Aloe extract 0.1%～30.0%;
Royal jelly 0.0%～30.0%; Pollen 0.0%～30.0%; Vitamin C 0.0%～30.0%;
Lysine 0.0%～30.0%; Alanine 0.0%～30.0%; Mineral mixture 0.1%～30.0%;
Auxiliary material 0.0%～95.0%.
In the present invention, described aloe extract is made by following method: select full more than 3 years, the ripe aloe leaf of growth cycle for use, with clear water clean up, go-no-go; Choose acceptable material and remove epidermis or directly squeeze the juice, obtain decolouring behind the thick juice of aloe, filtration and concentration; Subsequently the gained asparagus juice is carried out low-temperature quick-freezing (quick freezing temperature for-20 ℃ to-40 ℃), and be 8% in drying (temperature of charge is controlled at below 60 ℃) to water content under the vacuum of 13～130Pa; Pulverize at last, cross 100～200 mesh sieves.
In the present invention, described mineral mixture comprises calcium constituent, magnesium elements and zinc element.Wherein, calcium constituent is selected from calcium carbonate, calcium gluconae, calcium phosphate and calcium lactate etc.; Magnesium elements is selected from magnesium carbonate, magnesium gluconate and magnesium lactate etc.; The zinc element is selected from zinc carbonate, zinc gluconate, zinc citrate and zinc lactate etc.
In the present invention, described auxiliary material comprises following component by weight percentage:
Fruit powder 0.0%～30.0%; Flavoring essence 0.0%～5.0%; Sweetener 0.0%～5.0%;
Acid 0.0%～10.0%; Filler 0.0%～80.0%; Lubricant 0.0%～5.0%;
Stabilizing agent 0.0%～5.0%.
Wherein, Fruit powder is selected from one or more the mixing in orange powder, lemon powder, cherry powder, apple powder, the coconut palm powder etc.; Flavoring essence is selected from one or more the mixing in orange essence, lemon extract, cherry essence, flavoring apple essence, the cocoanut flavour etc.; Sweetener is selected from one or more the mixing in sweet etc. of Sucralose, AK sugar, Aspartame, mogroside, knob; Acid is selected from one or more the mixing in citric acid, malic acid, lactic acid, the citric acid etc.; Filler is selected from one or more the mixing in fructose, sugar alcohol, sucrose, starch, the dextrin etc.; Lubricant is selected from one or more the mixing in talcum powder, dolomol, silica, the stearic acid etc.; Stabilizing agent is selected from one or more the mixing in carragheen, konjac glucomannan, xanthans, pectin, the cyclodextrin etc.
Health food of the present invention can be made into the oral formulations such as pulvis, tablet, granule, hard capsule, soft capsule and oral liquid of various tastes.
In health food of the present invention, FOS has flora in the bidirectional modulation body as a kind of functional oligose, improve function of intestinal canal, improve immunity, reduce blood fat, promote the synthetic of vitamin, the protection liver promotes the effect that mineral matters such as Ca, Mg, Fe absorb; Taurine can increase the immune response of body, also has protection cell membrane, anti-oxidant and delay senility, promote brain growth and intelligence development, promotion to grow and multiple effect such as alleviating physical fatigue simultaneously; Aloe extract contains multiple effective active composition, can promote the biosynthesis of protein and nucleic acid, regulates the growth of cell, improves the immunity of human body; Royal jelly has promotion and grows, strengthens metabolism, improves effects such as immunity, prevent disease and supplemental treatment; Pollen can promote the hematopoiesis function of central immune organ marrow, improves the activity of thymin and the activate the phagocytic capacity of macrophage, increases leucocyte and the lymphocytic quantity of T, thereby strengthens the immunologic function of human body; Vitamin C helps the synthetic cysteine of immunoglobulin (Ig) by cystine is reduced into, make the sulfhydryl oxidase on the new immunoglobulin (Ig) peptide bond that synthesizes become disulfide bond after being oxidized to the dehydrogenation vitamin C, thereby promote the generation of immunoglobulin (Ig), performance strengthens the effect of immunity; Lysine the absorption that promotes protein and utilization, balanced nutritious, improve nervous function, strengthen function of immune system, the aspect all has extremely important physiological significance to prevent that osteoporosis and promotion from growing etc.; Alanine can replenish amino acid needed by human body as nutritious supplementary pharmaceutical, and can improve the local flavor of product; And mineral matter all has inseparable getting in touch with the various physiological functions of human body.
The present invention is according to the Human Physiology needs, and the raw material of above-mentioned various exact efficacy is carried out scientific composition, has guaranteed the effect of health food of the present invention.In addition, the above-mentioned raw materials wide material sources, the raw material elite that plant and animal material is wherein not only arranged, also have human body essential amino acid, vitamin and mineral matter, be aided with the functional oligose that promotes that mineral matter absorbs, make each raw material in human body, bring into play mutual promoting action, more help the absorption of functional component, thus more effective, the more powerful efficacy effect of performance.
Description of drawings
Fig. 1 is the pulvis preparation technology flow chart of health food of the present invention;
Fig. 2 is the tablet producing technology flow chart of health food of the present invention;
Fig. 3 is the granule preparation technology flow chart of health food of the present invention.
Fig. 4 is the hard capsule preparation technology flow chart of health food of the present invention.
Fig. 5 is the soft capsule preparation technology flow chart of health food of the present invention.
Fig. 6 is the oral liquid preparation technology flow chart of health food of the present invention.
The specific embodiment
Embodiment one: pulvis
Take by weighing each component according to following percentage by weight:
FOS 10.0%; Taurine 3.0%; Aloe extract 0.6%;
Vitamin C 1.2%; Pollen 1.0%; Mineral mixture 3.0%;
Orange powder 5.0%; Fructose 20.0%; Antierythrite 56.2%.
Load weighted all components is pulverized, is sieved, drop into then in the mixing apparatus, to be mixed evenly after, carry out packing and get final product.
Embodiment two: pulvis
Take by weighing each component according to following percentage by weight:
FOS 8.0%; Taurine 2.0%; Aloe extract 1.0%;
Vitamin C 1.0%; Lysine 4.0%; Mineral mixture 2.0%;
Lemon powder 2.0%; Fructose 20.0%; Antierythrite 60.0%.
Load weighted all components is pulverized, is sieved, drop into then in the mixing apparatus, to be mixed evenly after, carry out packing and get final product.
Embodiment three: pulvis
Take by weighing each component according to following percentage by weight:
Royal jelly freeze-dried powder 3.0%; Alanine 2.0%; Pollen 0.8%;
Aloe extract 1.0%; Fructose 25.0%; AK sugar 0.1%;
Mineral mixture 1.0%; Citric acid 0.6%; Malic acid 1.2%;
Antierythrite 64.8%; Carragheen 0.5%.
Load weighted all components is pulverized, is sieved, drop into then in the mixing apparatus, to be mixed evenly after, carry out packing and get final product.
Embodiment four: tablet
Take by weighing each component according to following percentage by weight:
Aloe extract 2.0%; FOS 18.0%; Taurine 5.0%;
Royal jelly freeze-dried powder 1.0%; Catergen .0%; Orange powder 3.5%;
Mineral mixture 3.5%; Sorbierite 64.3%; Silica 0.3%;
Dolomol 0.4%.
Load weighted all components is pulverized, is sieved, drop into then in the mixing apparatus, to be mixed evenly after, by the tablet press machine compressing tablet.
Embodiment five: tablet
Take by weighing each component according to following percentage by weight:
Aloe extract 2.0%; FOS 10.0%; Lysine 5.0%;
Mineral mixture 2.0%; Vitamin C 1.5%; Lemon powder 1.0%;
Dolomol 0.4%; Silica 0.3%; Sweet mellow wine 50.0%;
Isomalt 27.8%.
Load weighted all components is pulverized, is sieved, drop into then in the mixing apparatus, to be mixed evenly after, by the tablet press machine compressing tablet.
Embodiment six: granule
Take by weighing each component according to following percentage by weight:
Aloe extract 1.0%; FOS 10.0%; Alanine 5.0%;
Mineral mixture 2.0%; Vitamin C 1.0%; Malic acid 1.5%;
Aspartame 0.1%; Orange powder 5.0%; Orange essence 0.5%;
HPMC 5.0%; Starch 15.0%; Dextrin 10.0%;
Isomalt 43.9%.
Load weighted all components is pulverized, is sieved, drop into then in the mixing apparatus, to be mixed evenly after, drop in the facility for granulating, add an amount of alcohol and make softwood, by the whole grain of pelletizing machine, particle is carried out abundant drying with drying equipment, carry out packing at last.
Embodiment seven: hard capsule
Take by weighing each component according to following percentage by weight:
Aloe extract 5.0%; FOS 35.0%; Taurine 15.0%;
Royal jelly freeze-dried powder 1.0%; Pollen 2.0%; Starch 32.0%;
Mineral mixture 10.0%.
Load weighted all components is pulverized, is sieved, drop into then in the mixing apparatus, to be mixed evenly after, by capsule filler capsule is filled.
Embodiment eight: soft capsule
Take by weighing each raw material components of rubber according to following percentage by weight:
Gelatin 36.0%; Glycerine 18.0%; Methyl p-hydroxybenzoate 0.06%;
Water 45.94%.
To change glue in the above-mentioned rubber raw material input glue jar, be transferred in the bucket of band attemperator after by colloid mill, be connected on the soft capsule pellet press, be used to prepare soft capsule peel changing good rubber solution.
Take by weighing each component of health food of the present invention according to following percentage by weight:
Aloe extract 0.5%; FOS 5.0%; Pollen 0.5%;
Mineral mixture 1.0%; Soybean oil 90.8%; Beeswax 2.0%;
Ditert-butylhydro quinone 0.2%.
Load weighted FOS, aloe extract, pollen and mineral mixture are carried out coarse crushing earlier, and it is broken, standby to carry out fine powder subsequently; With alleged soybean oil, beeswax and the ditert-butylhydro quinone heating for dissolving of obtaining, drop in the above-mentioned standby material, stir, make its emulsification; Obtain uniform and stable emulsion by colloid mill then.Above-mentioned emulsion is put into reservoir, be injected in the soft capsule peel, suppress, the soft capsule that presses is cleaned, by drying equipment soft capsule is cured at last by the soft capsule pellet press.
Embodiment nine: oral liquid
Take by weighing each component according to following percentage by weight:
Aloe extract 0.4%; Sucrose 30.0%; Taurine 5.0%;
Mineral mixture 0.5%; Pectin 0.5%; Lemon powder 1.5%;
FOS 10.0%; Water 52.1%.
Load weighted all components is dropped in the water, fully after the dissolving, solution is transferred in the oral liquid bottle placer, inject in the vial sterilization.
Embodiment ten
According to the pertinent regulations of health ministry " health food check and assessment technique standard " (version in 2003), prepared powder product is carried out toxicity and function test.
1, toxicological test assay:
1) acute oral toxicity test: the acute oral MTD of SD rat greater than 20g/kg.bw, is belonged to non-toxic type;
2) genetic toxicity test (Salmonella reversion test): PCEMNR micronucleus test and three genetic toxicity test results of mouse mirror deformity test are all negative, show that this product does not have mutagenesis;
3) 30 days feeding trials of rat: do not cause the ANOMALOUS VARIATIONS of rat holistic health, physiology, biochemical function and each important indicator of organ-tissue morphology, maximum no-effect dose is greater than 10.0g/kg.bw (human body recommended amounts 60 times).
2, function test assay:
Oral administration gives mouse (Balb/c) 1.7g/kg.bw, 3.3g/kg.bw and 5.0g/kg.bw dosage this product of (be equivalent to the side of censorship by ready samples respectively and recommend to take day 10 times, 20 times and 30 times of recommended doses), tests after 30 days.
In mouse delayed allergy test, antigen was attacked back 24 hours, and 5.0g/kg.bw dosage group is compared with control group mice, and its swelling degree of the paw has significant difference.In the mouse spleen lymphocyte transformation experiment, 3.3g/kg.bw and 5.0g/kg.bw dosage group are compared with control group mice, and its optical density difference has significant difference.In mice serum hemolysin determination test, 5.0g/kg.bw dosage group is compared with control group mice, and its antibody volume all has significant difference.Detect in the test at antibody-producting cell, each dosage group is compared with control group mice, and there were significant differences for its antibody-producting cell number.
Can think that according to evaluation criterion these inspection product have the enhancing immunity function.
Embodiment 11
The present invention carries out toxicity and function test according to the pertinent regulations of health ministry " health food check and assessment technique standard " (version in 2003) to prepared tablet product.
1, toxicological test assay:
1) acute toxicity test: the maximum tolerated dose MTD of the acute oral of male and female small white mouse is all greater than 20000mg/kg;
2) micronucleus test result: feminine gender;
3) sperm malformation test result: feminine gender;
4) Salmonella reversion test result: feminine gender;
5) 30 days feeding trials: the animal used as test growing state is good, hematological examination, and biochemical analysis, main dirty body is histological examination result when compare with control group, all no significant difference.
2, function test assay:
Sample can obviously strengthen the active and humoral immunity activity of cellular immunity, improves monokaryon-macrophage phagocytic ability, and increases the NK cytoactive.
Sample has the enhancing immunity function to mouse.
Claims (9)
1, a kind of have strengthen body immunity and additional mineral matter health care foods, comprise following component by weight percentage:
FOS 0.0%～60.0%; Taurine 0.0%～40.0%; Aloe extract 0.1%～30.0%;
Royal jelly 0.0%～30.0%; Pollen 0.0%～30.0%; Vitamin C 0.0%～30.0%;
Lysine 0.0%～30.0%; Alanine 0.0%～30.0%; Mineral mixture 0.1%～30.0%;
Auxiliary material 0.0%～95.0%.
2, health food according to claim 1 is characterized in that, described aloe extract is made by following method: select full more than 3 years, the ripe aloe leaf of growth cycle for use, with clear water clean up, go-no-go; Choose acceptable material and remove epidermis or directly squeeze the juice, obtain decolouring behind the thick juice of aloe, filtration and concentration; Subsequently the gained asparagus juice is carried out low-temperature quick-freezing, and to be dried to water content under the vacuum of 13～130Pa be 8%; Pulverize at last, cross 100～200 mesh sieves.
3, health food according to claim 1 is characterized in that: described mineral mixture comprises calcium constituent, magnesium elements and zinc element.
4, health food according to claim 3 is characterized in that: described calcium constituent is selected from calcium carbonate, calcium gluconae, calcium phosphate and calcium lactate.
5, health food according to claim 3 is characterized in that: described magnesium elements is selected from magnesium carbonate, magnesium gluconate and magnesium lactate.
6, health food according to claim 3 is characterized in that: described zinc element is selected from zinc carbonate, zinc gluconate, zinc citrate and zinc lactate.
7, health food according to claim 1 is characterized in that, described auxiliary material comprises following component by weight percentage:
Fruit powder 0.0%～30.0%; Flavoring essence 0.0%～5.0%; Sweetener 0.0%～5.0%;
Acid 0.0%～10.0%; Filler 0.0%～80.0%; Lubricant 0.0%～5.0%;
Stabilizing agent 0.0%～5.0%.
8, health food according to claim 1 is characterized in that: described health food is prepared to oral formulations.
9, health food according to claim 8 is characterized in that: described oral formulations comprises pulvis, tablet, granule, hard capsule, soft capsule and oral liquid.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200910039183A CN101543293A (en) | 2009-05-04 | 2009-05-04 | A health food with properties for intensifying human body immunity and supplementing mineral composition |
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| CN200910039183A CN101543293A (en) | 2009-05-04 | 2009-05-04 | A health food with properties for intensifying human body immunity and supplementing mineral composition |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102058103A (en) * | 2010-11-18 | 2011-05-18 | 吴昊 | Anoxia resistant composite nutrient |
| CN102239922A (en) * | 2010-05-13 | 2011-11-16 | 江苏星驰生物科技有限公司 | Colostrum formula powder |
| CN102429218A (en) * | 2011-10-29 | 2012-05-02 | 山西振东五和健康食品股份有限公司 | Nutritious food suitable for health care of middle-aged and elderly people |
| CN102429219A (en) * | 2011-10-29 | 2012-05-02 | 山西振东五和健康食品股份有限公司 | Nutritious food suitable for middle-aged and elderly people to improve organism functions |
| CN106820161A (en) * | 2017-02-17 | 2017-06-13 | 陕西必康制药集团控股有限公司 | Aloe mineral crystalline substance and preparation method thereof |
| CN107006819A (en) * | 2017-03-30 | 2017-08-04 | 南京老山药业股份有限公司 | A kind of royal jelly freeze-dried powder capsule and its processing method |
| CN115363205A (en) * | 2022-08-08 | 2022-11-22 | 完美（广东）日用品有限公司 | Composition with immunity enhancing and anti-inflammatory functions and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1634251A (en) * | 2004-10-11 | 2005-07-06 | 贵阳云岩西创药物科技开发有限公司 | Compound medicinal gel of aloe and its preparation method |
-
2009
- 2009-05-04 CN CN200910039183A patent/CN101543293A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1634251A (en) * | 2004-10-11 | 2005-07-06 | 贵阳云岩西创药物科技开发有限公司 | Compound medicinal gel of aloe and its preparation method |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102239922A (en) * | 2010-05-13 | 2011-11-16 | 江苏星驰生物科技有限公司 | Colostrum formula powder |
| CN102058103A (en) * | 2010-11-18 | 2011-05-18 | 吴昊 | Anoxia resistant composite nutrient |
| CN102429218A (en) * | 2011-10-29 | 2012-05-02 | 山西振东五和健康食品股份有限公司 | Nutritious food suitable for health care of middle-aged and elderly people |
| CN102429219A (en) * | 2011-10-29 | 2012-05-02 | 山西振东五和健康食品股份有限公司 | Nutritious food suitable for middle-aged and elderly people to improve organism functions |
| CN102429218B (en) * | 2011-10-29 | 2013-04-17 | 山西振东五和健康食品股份有限公司 | Nutritious food suitable for health care of middle-aged and elderly people |
| CN102429219B (en) * | 2011-10-29 | 2013-04-24 | 山西振东五和健康食品股份有限公司 | Nutritious food suitable for middle-aged and elderly people to improve organism functions |
| CN106820161A (en) * | 2017-02-17 | 2017-06-13 | 陕西必康制药集团控股有限公司 | Aloe mineral crystalline substance and preparation method thereof |
| CN107006819A (en) * | 2017-03-30 | 2017-08-04 | 南京老山药业股份有限公司 | A kind of royal jelly freeze-dried powder capsule and its processing method |
| CN115363205A (en) * | 2022-08-08 | 2022-11-22 | 完美（广东）日用品有限公司 | Composition with immunity enhancing and anti-inflammatory functions and preparation method thereof |
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Inventor after: Li Chenyue Inventor after: Ouyang Daofu Inventor after: Yu Qin Inventor after: Huang Chaoxia Inventor after: Zhang Lixin Inventor after: Hu Ruilian Inventor before: Hu Ruilian Inventor before: Li Chenyue Inventor before: Ouyang Daofu Inventor before: Yu Qin |
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Free format text: CORRECT: INVENTOR; FROM: HU RUILIAN LI CHENYUE OUYANG DAOFU YU QIN TO: LI CHENYUE OUYANG DAOFU YU QIN HUANG ZHAOXIA ZHANG LIXIN HU RUILIAN |
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Application publication date: 20090930 |