CN101541954B - 含有人脐带血衍生的间充质干细胞的组合物诱导神经前体细胞或神经干细胞分化和增殖为神经细胞的用途 - Google Patents
含有人脐带血衍生的间充质干细胞的组合物诱导神经前体细胞或神经干细胞分化和增殖为神经细胞的用途 Download PDFInfo
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86787506P | 2006-11-30 | 2006-11-30 | |
| US60/867,875 | 2006-11-30 | ||
| KR10-2006-0120479 | 2006-12-01 | ||
| KR1020060120479 | 2006-12-01 | ||
| KR1020060120479A KR100959995B1 (ko) | 2006-12-01 | 2006-12-01 | 인간 제대혈 유래 간엽 줄기세포를 유효성분으로 포함하는,신경전구세포 또는 신경줄기세포의 신경세포로의 분화 및증식 유도용 조성물 |
| PCT/KR2007/006084 WO2008066330A1 (en) | 2006-11-30 | 2007-11-29 | Use of a composition contaning human umbilical cord blood-derived mesenchymal stem cell for inducing differentiation and proliferation of neural precursor cells or neural stem cells to neural cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101541954A CN101541954A (zh) | 2009-09-23 |
| CN101541954B true CN101541954B (zh) | 2012-12-26 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2007800440974A Active CN101541954B (zh) | 2006-11-30 | 2007-11-29 | 含有人脐带血衍生的间充质干细胞的组合物诱导神经前体细胞或神经干细胞分化和增殖为神经细胞的用途 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9387226B2 (https=) |
| EP (1) | EP2099901B1 (https=) |
| JP (2) | JP2010511381A (https=) |
| CN (1) | CN101541954B (https=) |
| AU (1) | AU2007326171B2 (https=) |
| CA (1) | CA2669304C (https=) |
| MX (1) | MX2009005496A (https=) |
| WO (1) | WO2008066330A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200011604A (ko) | 2008-08-20 | 2020-02-03 | 안트로제네시스 코포레이션 | 개선된 세포 조성물 및 그의 제조 방법 |
| CN101831401A (zh) * | 2010-04-23 | 2010-09-15 | 天津昂赛细胞基因工程有限公司 | 体外诱导间充质干细胞分化为神经干细胞的方法 |
| US11286463B2 (en) | 2012-03-08 | 2022-03-29 | Advanced ReGen Medical Technologies, LLC | Reprogramming of aged adult stem cells |
| US9994814B2 (en) | 2013-04-09 | 2018-06-12 | Advanced ReGen Medical Technologies, LLC | Method for cellular restoration |
| CR20160307A (es) | 2013-12-20 | 2016-11-08 | Advanced Regen Medical Tech Llc | Composiciones para la restauración de células y métodos para la preparación y utilización de las mismas |
| CN113354744A (zh) | 2013-12-20 | 2021-09-07 | 弗雷德哈钦森癌症研究中心 | 带标签的嵌合效应分子及其受体 |
| US10772911B2 (en) | 2013-12-20 | 2020-09-15 | Advanced ReGen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
| WO2016068616A1 (ko) * | 2014-10-29 | 2016-05-06 | 차의과학대학교 산학협력단 | C3 또는 c1r 보체를 분비하는 태반 유래 세포 및 이를 포함하는 조성물 |
| EP3288570A4 (en) | 2015-04-29 | 2018-11-21 | Fred Hutchinson Cancer Research Center | Modified stem cells and uses thereof |
| TWI589698B (zh) | 2015-07-22 | 2017-07-01 | 中國醫藥大學 | 間質幹細胞、其純株化擴張之方法、其分離方法及其應用 |
| CN106701668B (zh) * | 2015-07-22 | 2020-12-29 | 中国医药大学 | 间质干细胞、其纯株化扩张的方法及其应用 |
| US11110129B2 (en) | 2015-07-22 | 2021-09-07 | China Medical University | Method for treating multiple sclerosis |
| ITUB20159750A1 (it) * | 2015-12-30 | 2017-06-30 | Alfredo Gorio | Metodo per la promozione ed il miglioramento delle proprieta? del tessuto adiposo, tessuto e cellule ottenute tramite detto metodo |
| CA3022275A1 (en) | 2016-04-28 | 2017-11-02 | Sapporo Medical University | Synapse formation agent |
| EP3436081A4 (en) | 2016-04-29 | 2019-07-24 | Advanced Regen Medical Technologies, LLC | Microrna compositions and methods of making and using same |
| JP7034949B2 (ja) * | 2016-05-25 | 2022-03-14 | テルモ ビーシーティー、インコーポレーテッド | 細胞の増殖 |
| US10717981B2 (en) | 2018-01-18 | 2020-07-21 | Advanced ReGen Medical Technologies, LLC | Therapeutic compositions and methods of making and using the same |
| WO2019237106A1 (en) * | 2018-06-08 | 2019-12-12 | University Of Virginia Patent Foundation | Compositions and methods for treating stroke |
| JPWO2022004822A1 (https=) * | 2020-06-30 | 2022-01-06 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1302534A1 (en) * | 2000-06-26 | 2003-04-16 | Renomedix Institute Inc. | Cell fraction containing cells capable of differentiating into neural cells |
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| US7354588B1 (en) | 1987-05-04 | 2008-04-08 | Dana Farber Cancer Institute | Functional derivatives of ICAM-1 with altered ability to bind LFA-1 or HRV |
| US5733542A (en) | 1990-11-16 | 1998-03-31 | Haynesworth; Stephen E. | Enhancing bone marrow engraftment using MSCS |
| US5837576A (en) | 1997-10-31 | 1998-11-17 | Vanguard International Semiconductor Corporation | Method for forming a capacitor using a silicon oxynitride etching stop layer |
| US6900299B1 (en) | 1999-03-11 | 2005-05-31 | University Of South Florida | Interrupting the interaction of intercellular adhesion molecule-1 and respiratory syncytial virus for prevention and treatment of infection |
| EP2177228A1 (en) | 1999-03-12 | 2010-04-21 | The Board Of Trustees Of The Leland Stanford Junior University | DNA vaccination for treatment of autoimmune disease |
| US6372494B1 (en) | 1999-05-14 | 2002-04-16 | Advanced Tissue Sciences, Inc. | Methods of making conditioned cell culture medium compositions |
| US20040208858A1 (en) | 2000-04-12 | 2004-10-21 | Gihan Tennekoon | Therapeutic uses for mesenchymal stromal cells |
| US20040037775A1 (en) | 2000-08-01 | 2004-02-26 | Siahaan Teruna J. | Leukocyte internalized peptide-drug conjugates |
| US7560280B2 (en) * | 2000-11-03 | 2009-07-14 | Kourion Therapeutics Gmbh | Human cord blood derived unrestricted somatic stem cells (USSC) |
| KR100449141B1 (ko) | 2001-04-19 | 2004-09-21 | (주)라이프코드 | 간엽 간세포를 신경세포로 분화시키는 방법 |
| EP1483371B1 (en) | 2002-02-19 | 2007-06-27 | Medipost, Co., Ltd. | Isolation and culture-expansion methods of mesenchymal stem/progenitor cells from umbilical cord blood, and differentiation method of umbilical cord blood-derived mesenchymal stem/progenitor cells into various mesenchymal tissues |
| US20090192105A1 (en) | 2002-02-20 | 2009-07-30 | Sirna Therapeutics, Inc. | RNA INTERFERENCE MEDIATED INHIBITION OF INTERCELLULAR ADHESION MOLECULE (ICAM) GENE EXPRESSION USING SHORT INTERFERING NUCELIC ACID (siNA) |
| KR100519227B1 (ko) | 2002-08-17 | 2005-10-07 | 서해영 | 간엽 줄기세포를 신경세포로 분화시키는 방법 |
| US20040203142A1 (en) | 2003-04-14 | 2004-10-14 | Reliance Life Sciences Pvt. Ltd. | Growth of neural precursor cells using umbilical cord blood serum and a process for the preparation thereof for therapeutic purposes |
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| US20060094064A1 (en) | 2003-11-19 | 2006-05-04 | Sandip Ray | Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids |
| EP1767617A1 (en) | 2005-09-26 | 2007-03-28 | Letizia Mazzini | Mesenchymal stem cells isolation and expansion method and uses thereof |
| EP1951665A1 (en) | 2005-11-14 | 2008-08-06 | Dominion Pharmakine S.L. | Novel inhibitors of the lfa-1/icam-1 interaction, and uses thereof |
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| KR100792184B1 (ko) | 2006-05-12 | 2008-01-07 | 재단법인서울대학교산학협력재단 | 개의 제대혈, 태반 및 개 태아의 심장 유래 다분화능 성체줄기세포, 그 제조방법 및 이를 함유하는 세포 치료제 |
| KR20080049562A (ko) | 2006-11-30 | 2008-06-04 | 가톨릭대학교 산학협력단 | 제대혈 유래 간엽 줄기세포를 유효성분으로 포함하는 신경손상 질환 치료제 |
| KR20100054711A (ko) | 2008-11-14 | 2010-05-25 | 메디포스트(주) | 간엽 줄기세포 또는 이의 배양액을 포함하는 신경질환의 예방 또는 치료용 조성물 |
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2007
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- 2007-11-29 AU AU2007326171A patent/AU2007326171B2/en active Active
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- 2007-11-29 EP EP07851154.0A patent/EP2099901B1/en active Active
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2013
- 2013-08-01 JP JP2013160426A patent/JP5871865B2/ja active Active
- 2013-08-19 US US13/970,074 patent/US9439931B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1302534A1 (en) * | 2000-06-26 | 2003-04-16 | Renomedix Institute Inc. | Cell fraction containing cells capable of differentiating into neural cells |
Non-Patent Citations (3)
| Title |
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| Kadereit, Deeds, Haynesworth et al..Expansion of LTC-ICs and Maintenance of p21 and BCL-2 Expression in Cord Blood CD34 + /CD38 – Early Progenitors Cultured over Human MSCs as a Feeder Layer.《Stem Cells》.2002,第 20 卷573-582. * |
| Oscar K. Lee et al..Isolation of multipotent mesenchymal stem cells from umbilical cord blood.《Blood》.2003,第 103 卷(第 5 期),1669-1675. * |
| Yun Kyung Jang et al..Mesenchymal stem cells feeder layer from human umbilical cord blood for ex vivo expanded growth and proliferation of hematopoietic progenitor cells.《Ann Hematol》.2006,第 85 卷212-225. * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010511381A (ja) | 2010-04-15 |
| CN101541954A (zh) | 2009-09-23 |
| EP2099901A4 (en) | 2010-01-13 |
| US9387226B2 (en) | 2016-07-12 |
| AU2007326171B2 (en) | 2012-11-15 |
| CA2669304C (en) | 2016-10-25 |
| US20100074875A1 (en) | 2010-03-25 |
| CA2669304A1 (en) | 2008-06-05 |
| JP5871865B2 (ja) | 2016-03-01 |
| JP2013226159A (ja) | 2013-11-07 |
| US20130330306A1 (en) | 2013-12-12 |
| MX2009005496A (es) | 2009-06-03 |
| WO2008066330A8 (en) | 2009-05-28 |
| AU2007326171A1 (en) | 2008-06-05 |
| EP2099901A1 (en) | 2009-09-16 |
| HK1134688A1 (en) | 2010-05-07 |
| EP2099901B1 (en) | 2015-09-09 |
| US9439931B2 (en) | 2016-09-13 |
| WO2008066330A1 (en) | 2008-06-05 |
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