CN101537098A - Pharmaceutical composition with effects of awakening consciousness, clearing away heat and toxic material, eliminating dampness and discharging pus and preparation method thereof - Google Patents
Pharmaceutical composition with effects of awakening consciousness, clearing away heat and toxic material, eliminating dampness and discharging pus and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a pharmaceutical composition with effects of awakening consciousness, clearing away heat and toxic material, eliminating dampness and discharging pus and a preparation method thereof. The pharmaceutical composition is prepared by the following bulk drugs according to proportioning by weight: 80-320 parts of indian bread, 80-320 parts of frosythia fruit, 80-320 parts of pilose asiabell root, 80-320 parts of belamcanda rhizome, 80-320 parts of biond magnolia flower, 80-320 parts of grassleaved sweetflag rhizome, 80-320 parts of white atractylodes rhizome, 80-320 parts of tangerine peel, 50-200 parts of Chinese yam, 50-200 parts of cocklebur fruit, 50-200 parts of red peony root, 80-320 parts of dahurian angelica root, 50-200 parts of trichosanthes root, 50-200 parts of balloonflower root, 50-200 parts of liquorice and 50-200 parts of chuanxiong rhizome and is processed into clinically accepted tablets, capsules or granules through extracting, refining and other processes. The invention has the effects of awakening consciousness, clearing away heat and toxic material and eliminating dampness and discharging pus, is generally used for nasosinusitis syndrome or stagnated heat of lung channel of nose therapy and can be also used for throat swelling and pain; and the invention is usually used for acute nasosinusitis, acute episode of chronic nasosinusitis and acute faucitis nowadays.
Description
Technical field:
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to a kind of drug regimen and preparation method thereof with awakening consciousness, heat-clearing and toxic substances removing, damp eliminating evacuation of pus effect.
Technical background
Sinusitis, the traditional Chinese medical science are called " nasal sinusitis ", are a kind of very otorhinolaryngology diseases of seeing more, in adult and child higher sickness rate are arranged all, and China mainly is distributed in the refrigerant latitudes morbidity.Chronic sinusitis is because the course of disease is long, and outbreak repeatedly is difficult to cure.
The clinical manifestation of sinusitis has following symptom:
1. sinusitis often is secondary to sense or acute rhinitis, and fear of cold, heating, inappetence, constipation, whole body discomfort etc. appear at this moment original sx.Diseases such as children's can vomit, diarrhoea, cough.
2. how bilateral persistence nasal obstruction can appear-the side persistence, can take place by chance.
3. patient's pus nasal mucus increases and is difficult for blowing to the greatest extent, as flowing into pharyngeal backward and during lower respiratory tract, stimulating pharynx, larynx mucosa, causes cough and expectoration, even feels sick.
4. frons is painful, rises morning gently, and is afternoon heavy.Also have buccal portion distending pain or the above-listed pain of grinding one's teeth in sleep, be mostly maxillary sinusitis.
5. it is painful to play the sense frons morning, and gradually increase the weight of in Zhejiang, alleviates in the afternoon, all disappears to night, and this may be a frontal sinusitis.
6. headache is lighter, is confined to endocanthion or nasion portion, also may be radiated to head, and many worms ethmoiditis causes.
7. eyeball depths pain can emit to head, also goes out to see light, afternoon heavy occipital headache in morning, and reaching may be sphenoiditis.
8. chronic sinusitis also has following characteristics except that symptoms such as nasal obstruction, watery nasal discharge, headache: (1) headache is lighter, general vexed pain, the dull pains of belonging to more.(2) hyposmia or disappearance.(3) have a headache and to alleviate after rest, nose drops, steam suction or the nasal airflow drain.(4) cough, bow, bend over, have a headache when exerting oneself and increase the weight of.(5) smoking, drink, can increase the weight of when excited headache.(6) can cause lassitude, easy sleepy, dizzy, hypomnesis, absent minded or the like sometimes.
The chronic purulent pathological changes of sinusitis and tonsil, tooth all should be considered as the infection focus of existence in the body, its importance think more not as the back both and often out in the cold, but clinical showing, sinusitis is once healing, often make the doing well,improving of some disease such as rheumatic fever, polyarthritis, nephritis etc. or alleviate, sinusitis causes the reason of other pathological changes, may be 1. direct infection: the direct stimulation of hole intracavity purulent secretion.2. through lymph or hematogenous metastasis: suppurative infection in the nasal sinuses, its antibacterial or toxin can enter in lymph or the blood, be transferred to the elsewhere and various pathological changes take place.3. organize bacteriotoxin generation anaphylaxis in the nasal sinuses at a distance.Therefore sinusitis needs actively treatment timely, and the present invention is a raw material with the All Pure Nature Chinese herbal medicine, forms in conjunction with herbal pharmaceutical technology refinement now, has the effect of awakening consciousness, heat-clearing and toxic substances removing, damp eliminating evacuation of pus.
Summary of the invention:
One of purpose of the present invention provides a kind of drug regimen with awakening consciousness, heat-clearing and toxic substances removing, damp eliminating evacuation of pus effect.
Another object of the present invention provides the preparation method of this drug regimen.
Medicine of the present invention is made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made (part is unit of weight) by following raw materials according:
1. write out a prescription:
Poria 80-320 part Fructus Forsythiae 80-320 part Radix Codonopsis 80-320 part
Rhizoma Belamcandae 80-320 part Flos Magnoliae 80-320 part Rhizoma Acori Graminei 80-320 part
Rhizoma Atractylodis Macrocephalae 80-320 part Pericarpium Citri Reticulatae 80-320 part Rhizoma Dioscoreae 50-200 part
Fructus Xanthii 50-200 part Radix Paeoniae Rubra 50-200 part Radix Angelicae Dahuricae 80-320 part
Radix Trichosanthis 50-200 part Radix Platycodonis 50-200 part Radix Glycyrrhizae 50-200 part
Rhizoma Chuanxiong 50-200 part
The active component that preferred following raw materials according is made, curative effect is better:
160 parts of 160 parts of Radix Codonopsis of 160 parts of Fructus Forsythiaes of Poria
160 parts of 160 parts of Rhizoma Acori Graminei of 160 parts of Flos Magnoliae of Rhizoma Belamcandae
100 parts of 160 portions of Rhizoma Dioscoreaes of 160 parts of Pericarpium Citri Reticulataes of the Rhizoma Atractylodis Macrocephalae
160 parts of 100 parts of Radixs Angelicae Dahuricae of 100 parts of Radix Paeoniae Rubra of Fructus Xanthii
50 parts in 100 portions of Radix Glycyrrhizaes of 50 parts of Radix Platycodoniss of Radix Trichosanthis
100 parts of Rhizoma Chuanxiongs
The active ingredient preparation method of medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.
The following preparation method preparation of preferred employing:
2. preparation technology
(1) Radix Codonopsis, Rhizoma Chuanxiong are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Poria, Fructus Forsythiae, Rhizoma Belamcandae, Flos Magnoliae, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae, Fructus Xanthii, Radix Paeoniae Rubra, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Platycodonis, Radix Glycyrrhizae decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, concentrating under reduced pressure becomes relative density to be the thick paste of 1.20 (60 ℃), and is standby;
(3) step (1) gained clear paste and (2) gained thick paste are merged mixing, add the conventional adjunct ingredient of pharmacy acceptable, drying is ground into fine powder, makes granule, capsule and tablet.
Adopt mutual compatibility of above-mentioned raw material of Chinese medicine and preparation method thereof, distinctive active constituents of medicine among the present invention, full side has the effect of awakening consciousness, heat-clearing and toxic substances removing, damp eliminating evacuation of pus, is used for the nasal sinusitis card more, or the hot and suffocating card of the lung meridian of nose treatment, also can use for laryngopharynx swelling and pain.Modern acute sinusitis, acute paroxysm of chronic sinusitis, the acute pharyngolaryngitis of being used for more.
By the following examples technical scheme of the present invention is described further.
Embodiment 1: the preparation method of granule
1. write out a prescription
160 parts of 160 parts of Radix Codonopsis of 160 parts of Fructus Forsythiaes of Poria
160 parts of 160 parts of Rhizoma Acori Graminei of 160 parts of Flos Magnoliae of Rhizoma Belamcandae
100 parts of 160 portions of Rhizoma Dioscoreaes of 160 parts of Pericarpium Citri Reticulataes of the Rhizoma Atractylodis Macrocephalae
160 parts of 100 parts of Radixs Angelicae Dahuricae of 100 parts of Radix Paeoniae Rubra of Fructus Xanthii
50 parts in 100 portions of Radix Glycyrrhizaes of 50 parts of Radix Platycodoniss of Radix Trichosanthis
100 parts of Rhizoma Chuanxiongs
2. preparation technology
(1) Radix Codonopsis, Rhizoma Chuanxiong are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Poria, Fructus Forsythiae, Rhizoma Belamcandae, Flos Magnoliae, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae, Fructus Xanthii, Radix Paeoniae Rubra, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Platycodonis, Radix Glycyrrhizae decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, concentrating under reduced pressure becomes relative density to be the thick paste of 1.20 (60 ℃), and is standby;
(3) step (1) gained clear paste and (2) gained thick paste are merged mixing, add the conventional adjunct ingredient of pharmacy acceptable, drying is ground into fine powder, makes granule, promptly.
Embodiment 2: the preparation method of tablet
1. write out a prescription
160 parts of 160 parts of Radix Codonopsis of 160 parts of Fructus Forsythiaes of Poria
160 parts of 160 parts of Rhizoma Acori Graminei of 160 parts of Flos Magnoliae of Rhizoma Belamcandae
100 parts of 160 portions of Rhizoma Dioscoreaes of 160 parts of Pericarpium Citri Reticulataes of the Rhizoma Atractylodis Macrocephalae
160 parts of 100 parts of Radixs Angelicae Dahuricae of 100 parts of Radix Paeoniae Rubra of Fructus Xanthii
50 parts in 100 portions of Radix Glycyrrhizaes of 50 parts of Radix Platycodoniss of Radix Trichosanthis
100 parts of Rhizoma Chuanxiongs
2. preparation technology
(1) Radix Codonopsis, Rhizoma Chuanxiong are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Poria, Fructus Forsythiae, Rhizoma Belamcandae, Flos Magnoliae, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae, Fructus Xanthii, Radix Paeoniae Rubra, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Platycodonis, Radix Glycyrrhizae decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, concentrating under reduced pressure becomes relative density to be the thick paste of 1.20 (60 ℃), and is standby;
(3) with step (1) gained clear paste and (2) gained thick paste merging mixing, add the conventional adjunct ingredient of pharmacy acceptable, drying is ground into fine powder, the system granule, and drying, compacting is in blocks, promptly.
Embodiment 3: the preparation method of capsule
1. write out a prescription
160 parts of 160 parts of Radix Codonopsis of 160 parts of Fructus Forsythiaes of Poria
160 parts of 160 parts of Rhizoma Acori Graminei of 160 parts of Flos Magnoliae of Rhizoma Belamcandae
100 parts of 160 portions of Rhizoma Dioscoreaes of 160 parts of Pericarpium Citri Reticulataes of the Rhizoma Atractylodis Macrocephalae
160 parts of 100 parts of Radixs Angelicae Dahuricae of 100 parts of Radix Paeoniae Rubra of Fructus Xanthii
50 parts in 100 portions of Radix Glycyrrhizaes of 50 parts of Radix Platycodoniss of Radix Trichosanthis
100 parts of Rhizoma Chuanxiongs
2. preparation technology
(1) Radix Codonopsis, Rhizoma Chuanxiong are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Poria, Fructus Forsythiae, Rhizoma Belamcandae, Flos Magnoliae, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae, Fructus Xanthii, Radix Paeoniae Rubra, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Platycodonis, Radix Glycyrrhizae decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, concentrating under reduced pressure becomes relative density to be the thick paste of 1.20 (60 ℃), and is standby;
(3) step (1) gained clear paste and (2) gained thick paste are merged mixing, add the conventional adjunct ingredient of pharmacy acceptable, drying is ground into fine powder, makes granule, and drying is sieved, and incapsulates, promptly.
Claims (5)
1, a kind of drug regimen with awakening consciousness, heat-clearing and toxic substances removing, damp eliminating evacuation of pus effect is characterized in that being made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made by following raw materials according:
Poria 80-320 part Fructus Forsythiae 80-320 part Radix Codonopsis 80-320 part
Rhizoma Belamcandae 80-320 part Flos Magnoliae 80-320 part Rhizoma Acori Graminei 80-320 part
Rhizoma Atractylodis Macrocephalae 80-320 part Pericarpium Citri Reticulatae 80-320 part Rhizoma Dioscoreae 50-200 part
Fructus Xanthii 50-200 part Radix Paeoniae Rubra 50-200 part Radix Angelicae Dahuricae 80-320 part
Radix Trichosanthis 50-200 part Radix Platycodonis 50-200 part Radix Glycyrrhizae 50-200 part
Rhizoma Chuanxiong 50-200 part
2, a kind of drug regimen with awakening consciousness, heat-clearing and toxic substances removing, damp eliminating evacuation of pus effect according to claim 1 is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:
160 parts of 160 parts of Radix Codonopsis of 160 parts of Fructus Forsythiaes of Poria
160 parts of 160 parts of Rhizoma Acori Graminei of 160 parts of Flos Magnoliae of Rhizoma Belamcandae
100 parts of 160 portions of Rhizoma Dioscoreaes of 160 parts of Pericarpium Citri Reticulataes of the Rhizoma Atractylodis Macrocephalae
160 parts of 100 parts of Radixs Angelicae Dahuricae of 100 parts of Radix Paeoniae Rubra of Fructus Xanthii
50 parts in 100 portions of Radix Glycyrrhizaes of 50 parts of Radix Platycodoniss of Radix Trichosanthis
100 parts of Rhizoma Chuanxiongs
3, according to the described a kind of drug regimen of claim 1-2, it is characterized in that adopting following method to make with awakening consciousness, heat-clearing and toxic substances removing, damp eliminating evacuation of pus effect:
(1) Radix Codonopsis, Rhizoma Chuanxiong are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Poria, Fructus Forsythiae, Rhizoma Belamcandae, Flos Magnoliae, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae, Fructus Xanthii, Radix Paeoniae Rubra, the Radix Angelicae Dahuricae, Radix Trichosanthis, Radix Platycodonis, Radix Glycyrrhizae decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, concentrating under reduced pressure becomes relative density to be the thick paste of 1.20 (60 ℃), and is standby;
(3) step (1) gained clear paste and (2) gained thick paste are merged mixing, add the conventional adjunct ingredient of pharmacy acceptable, drying is ground into fine powder, makes granule, capsule and tablet.
4, according to any one described a kind of drug regimen among the claim 1-3, it is characterized in that this Chinese medicine composition is an oral formulations with awakening consciousness, heat-clearing and toxic substances removing, damp eliminating evacuation of pus effect.
5, according to the described a kind of drug regimen of claim 3-4, it is characterized in that this Chinese medicine composition can be made into granule, capsule, tablet with awakening consciousness, heat-clearing and toxic substances removing, damp eliminating evacuation of pus effect.
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| CN 200810102438 CN101537098A (en) | 2008-03-21 | 2008-03-21 | Pharmaceutical composition with effects of awakening consciousness, clearing away heat and toxic material, eliminating dampness and discharging pus and preparation method thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101933983A (en) * | 2010-08-27 | 2011-01-05 | 刘慧� | Traditional Chinese medicinal composition for treating allergic rhinitis, preparation thereof and preparation method thereof |
| CN103191290A (en) * | 2013-04-10 | 2013-07-10 | 成都中医药大学 | Pharmaceutical composition for treating nasosinusitis as well as preparation method and application thereof |
| CN103877440A (en) * | 2014-04-09 | 2014-06-25 | 樊万军 | Medicine for treating rhinitis |
| CN103948857A (en) * | 2014-05-13 | 2014-07-30 | 黄业武 | Pharmaceutical composition after chronic nasosinusitis endoscopic sinus surgery |
| CN103989848A (en) * | 2014-05-13 | 2014-08-20 | 吴任枝 | A pharmaceutical composition for chronic nasosinusitis after endoscopic surgery |
| CN104189703A (en) * | 2014-07-30 | 2014-12-10 | 严中明 | Traditional Chinese medicine composition for treating kidney-vitality deficiency type running nose |
| CN104258318A (en) * | 2014-07-30 | 2015-01-07 | 严中明 | Traditional Chinese medicine composition for treating lung qi deficiency and cold type rhinorrhea disease |
-
2008
- 2008-03-21 CN CN 200810102438 patent/CN101537098A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101933983A (en) * | 2010-08-27 | 2011-01-05 | 刘慧� | Traditional Chinese medicinal composition for treating allergic rhinitis, preparation thereof and preparation method thereof |
| CN103191290A (en) * | 2013-04-10 | 2013-07-10 | 成都中医药大学 | Pharmaceutical composition for treating nasosinusitis as well as preparation method and application thereof |
| CN103191290B (en) * | 2013-04-10 | 2015-03-11 | 成都中医药大学 | Pharmaceutical composition for treating nasosinusitis as well as preparation method and application thereof |
| CN103877440A (en) * | 2014-04-09 | 2014-06-25 | 樊万军 | Medicine for treating rhinitis |
| CN103948857A (en) * | 2014-05-13 | 2014-07-30 | 黄业武 | Pharmaceutical composition after chronic nasosinusitis endoscopic sinus surgery |
| CN103989848A (en) * | 2014-05-13 | 2014-08-20 | 吴任枝 | A pharmaceutical composition for chronic nasosinusitis after endoscopic surgery |
| CN104189703A (en) * | 2014-07-30 | 2014-12-10 | 严中明 | Traditional Chinese medicine composition for treating kidney-vitality deficiency type running nose |
| CN104258318A (en) * | 2014-07-30 | 2015-01-07 | 严中明 | Traditional Chinese medicine composition for treating lung qi deficiency and cold type rhinorrhea disease |
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Open date: 20090923 |