CN101524441A - Chinese medicinal composition for lipid-lowering and weight-losing and preparation method thereof - Google Patents
Chinese medicinal composition for lipid-lowering and weight-losing and preparation method thereof Download PDFInfo
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- CN101524441A CN101524441A CN200810101481A CN200810101481A CN101524441A CN 101524441 A CN101524441 A CN 101524441A CN 200810101481 A CN200810101481 A CN 200810101481A CN 200810101481 A CN200810101481 A CN 200810101481A CN 101524441 A CN101524441 A CN 101524441A
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Abstract
The invention relates to a Chinese medicinal composition for lipid-lowering and weight-losing and a preparation method thereof. The Chinese medicinal composition is prepared from the following materials in portion by weight: 100 to 200 portions of radix polygoni multiflori preparata, 100 to 200 portions of cassia seed, 200 to 400 portions of hawthorn fruit, 50 to 100 portions of sadix notoginseng, 200 to 400 portions of paniculate swallowwort root, 100 to 200 potions of medlar, 200 to 400 portions of lotus leaf, and 50 to 100 portions of szechuan lovage rhizome; and the materials are subjected to extraction and refining, and are processed into any acceptable preparation formulation clinically, such as tablets, capsules, granules and the like. The Chinese medicinal composition has the efficacies of strengthening the spleen and replenishing qi, activating blood and regulating qi, relaxing bowels and removing food stagnation, and descending turbidity and promoting expectoration, and is mainly used for treating hyperlipidemia caused by phlegm and blood stasis, and symptoms of the hyperlipidemia are as follows: chest stuffiness, shortness of breath, hypodynamia, palpitation, dizziness, and the like.
Description
Technical field:
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to a kind of Chinese medicine composition of lowering blood-fat and reducing weight, the invention still further relates to the preparation method of this Chinese medicine composition.
Technical background
Social now, fat serious harm health, operating pressure is big, and the people of subhealth state can be found everywhere, and the associated conditions threat to life safety that its causes is so it has become a big killer of 21st century human health! On the other hand, along with progress of science and technology, expanding economy, the raising of living standards of the people, the people are also more and more higher to the requirement of quality of life, health to self is also more and more paid attention to, so people begin to adopt the natural resources of some non-invasives to come the resistance of enhancing body, slow down aging.
Obese people's lipid metabolism characteristics are: blood plasma free fatty acid raises, and lipid compositions such as cholesterol, triglyceride, total fat generally increase.Fat metabolic disturbance is described.Obese people's blood plasma cholesterol level 5.2 mMs/liter more than account for 55.8%.The man is after 60 years old, and the woman is after 50 years old, and blood plasma cholesterol level all will significantly raise.
When suffering from obesity, body reduces the mobilization utilization of free fatty, the free-fat acid accumulation in the blood, and the blood fat capacity raises.The patient of the hypertriglyceridemia that carbohydrate causes is fat easily.More or just often, the triglyceride of blood plasma raises when the carbohydrate of this class patient feed; And the intake of minimizing carbohydrate, hyperlipemia just can take a turn for the better even disappear.Equally, weight loss also can make these patients' plasma triglyceride drop to normal level.The rising of plasma cholesterol and triglyceride is directly proportional with obese degree.
Simple obesity early stage, negative and positive of qi and blood produces obviously unbalance as yet, the patient only has light symptoms, as giddy, heavy sensation of the body, weak, breathe hard, soreness of the waist and knees etc., but inspection does not still have related complication.This moment clinical treatment to need not meticulous typing dialectical, according to theory of Chinese medical science " fertile people's excessive phlegm is wet ", the water liquid metabolic function of the liver spleen kidney of duty is lacked of proper care.Expectorant is turbid to be detained blood vessels for YIN pathogen, and the variation of hyperamization liquid stream is normal, forms qi depression to blood stasis, and the expectorant stasis of blood is with sick.Confirm in conjunction with modern medicine study: " expectorant is turbid " patient's cholesterolemia, triglyceride and lipoprotein are apparently higher than non-" expectorant is turbid " type patient.So treatment serves as the treatment rule with invigorating the spleen and benefiting QI, blood circulation promoting regulates qi, purging FU-organs intestinal stasis relieving, the turbid descending dissipating fluid-retention.
The present invention forms in conjunction with the modern Chinese medicine preparation technique for folk remedy, and all medical instruments have the anabolic effect that promotes the drainage of enteral fat, control to absorb, suppress serum cholesterol, triglyceride and lipoprotein in the side.All medicines share have invigorating the spleen and benefiting QI, the effect of blood circulation promoting regulates qi, purging FU-organs intestinal stasis relieving, the turbid descending dissipating fluid-retention, be mainly used in and be used for the hyperlipemia that the mutual resistance of the expectorant stasis of blood causes, card is seen: uncomfortable in chest, breathe hard, weak, cardiopalmus, dizziness etc.
Summary of the invention:
One of purpose of the present invention provides a kind of Chinese medicine composition of lowering blood-fat and reducing weight.
Another purpose of the present invention provides the preparation method of this Chinese medicine composition.
Chinese medicine of the present invention is made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made (part is unit of weight) by following raw materials according:
1, prescription:
Radix Polygoni Multiflori Preparata 100-200 part Semen Cassiae 100-200 part Fructus Crataegi 200-400 part
Radix Notoginseng 50-100 part Radix Cynanchi Paniculati 200-400 part Fructus Lycii 100-200 part
Folium Nelumbinis 200-400 part Rhizoma Chuanxiong 50-100 part
The active component that preferred following raw materials according is made, curative effect is better:
300 parts of 150 portions of Fructus Crataegis of 150 parts of Semen Cassiaes of Radix Polygoni Multiflori Preparata
120 parts of 250 parts of Fructus Lycii of 60 parts of Radix Cynanchi Paniculatis of Radix Notoginseng
60 parts of 400 parts of Rhizoma Chuanxiongs of Folium Nelumbinis
The active ingredient preparation method of Chinese medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.
The following preparation method preparation of preferred employing:
2, preparation technology:
(1) get Radix Notoginseng, Rhizoma Chuanxiong, pulverize separately becomes fine powder, and is standby;
(2) Semen Cassiae, Fructus Crataegi, Radix Cynanchi Paniculati, Fructus Lycii are decocted with water 2-3 time, each 1-2 hour, collecting decoction filtered, and filtrate is concentrated into the clear paste that relative density is 1.28～1.30 (80 ℃), and is standby;
(3) Radix Polygoni Multiflori Preparata, Folium Nelumbinis add the Diluted Alcohol reflux, extract, three times, and 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated into relative density and is the clear paste of 1.28～1.30 (80 ℃), and is standby;
(4) step (1) gained fine powder and step (2), (3) gained clear paste are merged, mixing, drying under reduced pressure is pulverized, and sieves, and adds appropriate amount of auxiliary materials and makes different oral formulations.
Effective ingredient of the present invention can be prepared into oral formulations such as granule, capsule, tablet, oral liquid, effervescent tablet, dispersible tablet etc. with acceptable accessories.
The effective ingredient of drug regimen of the present invention has the effect of invigorating the spleen and benefiting QI, blood circulation promoting regulates qi, purging FU-organs intestinal stasis relieving, the turbid descending dissipating fluid-retention, is mainly used in to be used for the hyperlipemia that the mutual resistance of the expectorant stasis of blood causes, card is seen: uncomfortable in chest, breathe hard, weak, cardiopalmus, dizziness etc.
The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.
The specific embodiment
Embodiment 1: the preparation of granule
1, prescription:
300 parts of 150 portions of Fructus Crataegis of 150 parts of Semen Cassiaes of Radix Polygoni Multiflori Preparata
120 parts of 250 parts of Fructus Lycii of 60 parts of Radix Cynanchi Paniculatis of Radix Notoginseng
60 parts of 400 parts of Rhizoma Chuanxiongs of Folium Nelumbinis
2, preparation technology:
(1) get Radix Notoginseng, Rhizoma Chuanxiong, pulverize separately becomes fine powder, and is standby;
(2) Semen Cassiae, Fructus Crataegi, Radix Cynanchi Paniculati, Fructus Lycii are decocted with water 2-3 time, each 1-2 hour, collecting decoction filtered, and filtrate is concentrated into the clear paste that relative density is 1.28～1.30 (80 ℃), and is standby;
(3) Radix Polygoni Multiflori Preparata, Folium Nelumbinis add the Diluted Alcohol reflux, extract, three times, and 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated into relative density and is the clear paste of 1.28～1.30 (80 ℃), and is standby;
(4) step (1) gained fine powder and step (2), (3) gained clear paste are merged, mixing, drying under reduced pressure adds dextrin and pulverizes, and sieves, and makes granule, promptly.
Embodiment 2: the preparation of tablet
1, prescription:
300 parts of 150 portions of Fructus Crataegis of 150 parts of Semen Cassiaes of Radix Polygoni Multiflori Preparata
120 parts of 250 parts of Fructus Lycii of 60 parts of Radix Cynanchi Paniculatis of Radix Notoginseng
60 parts of 400 parts of Rhizoma Chuanxiongs of Folium Nelumbinis
2, preparation technology:
(1) get Radix Notoginseng, Rhizoma Chuanxiong, pulverize separately becomes fine powder, and is standby;
(2) Semen Cassiae, Fructus Crataegi, Radix Cynanchi Paniculati, Fructus Lycii are decocted with water 2-3 time, each 1-2 hour, collecting decoction filtered, and filtrate is concentrated into the clear paste that relative density is 1.28～1.30 (80 ℃), and is standby;
(3) Radix Polygoni Multiflori Preparata, Folium Nelumbinis add the Diluted Alcohol reflux, extract, three times, and 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated into relative density and is the clear paste of 1.28～1.30 (80 ℃), and is standby;
(4) step (1) gained fine powder and step (2), (3) gained clear paste are merged, mixing, drying under reduced pressure is pulverized the back and is added starch, pelletizing press sheet, promptly.
Embodiment 3: the preparation of capsule
1, prescription:
300 parts of 150 portions of Fructus Crataegis of 150 parts of Semen Cassiaes of Radix Polygoni Multiflori Preparata
120 parts of 250 parts of Fructus Lycii of 60 parts of Radix Cynanchi Paniculatis of Radix Notoginseng
60 parts of 400 parts of Rhizoma Chuanxiongs of Folium Nelumbinis
2, preparation technology:
(1) get Radix Notoginseng, Rhizoma Chuanxiong, pulverize separately becomes fine powder, and is standby;
(2) Semen Cassiae, Fructus Crataegi, Radix Cynanchi Paniculati, Fructus Lycii are decocted with water 2-3 time, each 1-2 hour, collecting decoction filtered, and filtrate is concentrated into the clear paste that relative density is 1.28～1.30 (80 ℃), and is standby;
(3) Radix Polygoni Multiflori Preparata, Folium Nelumbinis add the Diluted Alcohol reflux, extract, three times, and 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated into relative density and is the clear paste of 1.28～1.30 (80 ℃), and is standby;
(4) step (1) gained fine powder and step (2), (3) gained clear paste are merged, mixing, drying under reduced pressure is pulverized the back and is added starch, makes granule, incapsulates, promptly.
Claims (5)
1, a kind of Chinese medicine composition of lowering blood-fat and reducing weight is characterized in that being made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made by following raw materials according:
Radix Polygoni Multiflori Preparata 100-200 part Semen Cassiae 100-200 part Fructus Crataegi 200-400 part
Radix Notoginseng 50-100 part Radix Cynanchi Paniculati 200-400 part Fructus Lycii 100-200 part
Folium Nelumbinis 200-400 part Rhizoma Chuanxiong 50-100 part
2, the Chinese medicine composition of a kind of lowering blood-fat and reducing weight according to claim 1 is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:
300 parts of 150 portions of Fructus Crataegis of 150 parts of Semen Cassiaes of Radix Polygoni Multiflori Preparata
120 parts of 250 parts of Fructus Lycii of 60 parts of Radix Cynanchi Paniculatis of Radix Notoginseng
60 parts of 400 parts of Rhizoma Chuanxiongs of Folium Nelumbinis
3,, it is characterized in that adopting following method to make according to the Chinese medicine composition of the described a kind of lowering blood-fat and reducing weight of claim 1-2:
(1) get Radix Notoginseng, Rhizoma Chuanxiong, pulverize separately becomes fine powder, and is standby;
(2) Semen Cassiae, Fructus Crataegi, Radix Cynanchi Paniculati, Fructus Lycii are decocted with water 2-3 time, each 1-2 hour, collecting decoction filtered, and filtrate is concentrated into the clear paste that relative density is 1.28～1.30 (80 ℃), and is standby;
(3) Radix Polygoni Multiflori Preparata, Folium Nelumbinis add the Diluted Alcohol reflux, extract, three times, and 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated into relative density and is the clear paste of 1.28～1.30 (80 ℃), and is standby;
(4) step (1) gained fine powder and step (2), (3) gained clear paste are merged, mixing, drying under reduced pressure is pulverized, and sieves, and adds appropriate amount of auxiliary materials and makes different oral formulations.
4,, it is characterized in that this Chinese medicine composition is an oral formulations according to the Chinese medicine composition of any one described a kind of lowering blood-fat and reducing weight among the claim 1-3.
5,, it is characterized in that this Chinese medicine composition can be made into granule, capsule, tablet according to the Chinese medicine composition of the described a kind of lowering blood-fat and reducing weight of claim 5.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810101481A CN101524441A (en) | 2008-03-07 | 2008-03-07 | Chinese medicinal composition for lipid-lowering and weight-losing and preparation method thereof |
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| CN200810101481A CN101524441A (en) | 2008-03-07 | 2008-03-07 | Chinese medicinal composition for lipid-lowering and weight-losing and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904971A (en) * | 2010-05-29 | 2010-12-08 | 兰州古驰生物科技有限公司 | Chinese medicinal composition for preventing and treating obesity and preparation thereof |
| CN102920786A (en) * | 2012-11-16 | 2013-02-13 | 武汉代代木生物科技有限公司 | Method for preparing preparation capable of protecting liver, resisting tumors, reducing blood lipid and regulating immunity |
| US8859006B2 (en) | 2010-07-05 | 2014-10-14 | Jianzhong Ma | Semen cassiae soft capsule for reducing fat and losing weight and preparation method thereof |
| CN104784502A (en) * | 2015-05-13 | 2015-07-22 | 戴惠英 | Medicament for treating hyperlipidemia |
| CN105288340A (en) * | 2015-11-09 | 2016-02-03 | 陈慧珊 | Traditional Chinese medicine oral liquid for reducing weight and preparation method |
| CN109170894A (en) * | 2018-09-30 | 2019-01-11 | 江西瑞龙药业有限公司 | A kind of cape jasmine health care product and preparation method thereof for reducing blood sugar and blood lipid |
-
2008
- 2008-03-07 CN CN200810101481A patent/CN101524441A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904971A (en) * | 2010-05-29 | 2010-12-08 | 兰州古驰生物科技有限公司 | Chinese medicinal composition for preventing and treating obesity and preparation thereof |
| CN101904971B (en) * | 2010-05-29 | 2011-11-02 | 兰州古驰生物科技有限公司 | Chinese medicinal composition for preventing and treating obesity and preparation thereof |
| US8859006B2 (en) | 2010-07-05 | 2014-10-14 | Jianzhong Ma | Semen cassiae soft capsule for reducing fat and losing weight and preparation method thereof |
| CN102920786A (en) * | 2012-11-16 | 2013-02-13 | 武汉代代木生物科技有限公司 | Method for preparing preparation capable of protecting liver, resisting tumors, reducing blood lipid and regulating immunity |
| CN104784502A (en) * | 2015-05-13 | 2015-07-22 | 戴惠英 | Medicament for treating hyperlipidemia |
| CN105288340A (en) * | 2015-11-09 | 2016-02-03 | 陈慧珊 | Traditional Chinese medicine oral liquid for reducing weight and preparation method |
| CN109170894A (en) * | 2018-09-30 | 2019-01-11 | 江西瑞龙药业有限公司 | A kind of cape jasmine health care product and preparation method thereof for reducing blood sugar and blood lipid |
| CN109170894B (en) * | 2018-09-30 | 2021-05-07 | 江西瑞龙药业有限公司 | Gardenia health-care product for reducing blood sugar and blood fat and preparation method thereof |
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Open date: 20090909 |