CN104784502A

CN104784502A - Medicament for treating hyperlipidemia

Info

Publication number: CN104784502A
Application number: CN201510242336.3A
Authority: CN
Inventors: 戴惠英
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-05-13
Filing date: 2015-05-13
Publication date: 2015-07-22

Abstract

The invention relates to a medicament for treating hyperlipidemia. The medicament is prepared from the following raw pharmaceutical materials in parts by weight: 160 parts of root of toothed Habenaria, 130 parts of lysimachia microcarpa, 150 parts of lindera angustifolia, 130 parts of lanceolate cynoglossum, 150 parts of broken-bowl flower, 120 parts of four-leaf clover, 100 parts of oyster rhoeo, 100 parts of gynura divaricata, 80 parts of meliosma rigida, 80 parts of conyza canadensis, 60 parts of diplazium donianum, 70 parts of Henry clematis root, 80 parts of swallowwort root, 60 parts of wood rush, 50 parts of viola inconspicua and 30 parts of glycyrrhiza uralensis. The medicament for treating hyperlipidemia, disclosed by the invention, uses natural drugs, thus having the advantages of high effect taking speed, good treatment effect and no toxic or side effect.

Description

A kind of medicament for the treatment of hyperlipemia

Technical field

The present invention relates to field of medicaments, specifically, relate to a kind of medicament for the treatment of hyperlipemia.

Background technology

Hyperlipemia means the paranormal a kind of symptom of lipid concentration in blood plasma, and due to lipid major part in blood plasma and protein bound in blood plasma, therefore primary disease is also called hyperlipoproteinemia.Blood fat comprises lipoids and fat, and lipoids is phospholipid, glycolipid, sterin and steroid mainly, and fat is triglyceride mainly.Cholesterol in blood plasma is except from except food, and the liver of human body and large intestine also can synthesize, and when taking in synthesis in hypercholesterolia or liver in food, too much, Cholesterol Excretion is very few, biliary obstruction, all can cause hypercholesterolemia.Triglyceride is that in food, fat is after intestinal absorption, and digested is non-esterified fatty acid and triglyceride, enters enteric cavity, through intestinal mucosa cells resynthesis triglyceride, and forms Chylomicron, enters blood circulation through thoracic duct.Equally, triglyceride also can utilize carbohydrate in liver---and saccharide is that raw material synthesizes, and visible polyphagia saccharide also can make triglyceride raise.

Studying the method for effectively treating hyperlipemia clinically always.

Summary of the invention

The object of this invention is to provide a kind of medicament for the treatment of hyperlipemia.

In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of hyperlipemia, it is made up by weight of following bulk drugs: Radix Habenariae Dentatae 160 parts, fruitlet Herba lysimachiae capillipedis 130 parts, Lindera angustifolia Cheng 150 parts, Herba Cynoglossi lanceolati 130 parts, Herba Anemones Hupehensis 150 parts, Herba Galii Bungei 120 parts, Flos Rhoeo discolorae 100 parts, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 100 parts, Cortex Meliosmatis rigidae Radicis 80 parts, Conyza canadensis (L.) Cronq. 80 parts, 60 parts, comb leaf, Radix Clematidis Henryi 70 parts, Radix Cynanchi Paniculati 80 parts, Cor Cervi grass 60 parts, Herba Violae japonicae 50 parts and 30 parts, Radix Glycyrrhizae.

Preferably, described medicament can make tablet, dispersible tablet, rapidly dissolving tablet, powder or granule.

In the present compositions, Radix Habenariae Dentatae, fruitlet Herba lysimachiae capillipedis are monarch drug, Lindera angustifolia Cheng, Herba Cynoglossi lanceolati, Herba Anemones Hupehensis, Herba Galii Bungei, Flos Rhoeo discolorae are ministerial drug, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani), Cortex Meliosmatis rigidae Radicis, Conyza canadensis (L.) Cronq., comb leaf, Radix Clematidis Henryi, Radix Cynanchi Paniculati, Cor Cervi grass, Herba Violae japonicae are adjuvant drug, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, for making medicine.

Use natural drug in the medicament for the treatment of hyperlipemia of the present invention, therefore it has instant effect, good effect, the advantage that has no side effect.

Detailed description of the invention

Below by way of the description of detailed description of the invention, the invention will be further described, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, various amendment or improvement can be made, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.

The preparation of embodiment powder of the present invention

Get Radix Habenariae Dentatae 160 grams, fruitlet Herba lysimachiae capillipedis 130 grams, Lindera angustifolia Cheng 150 grams, Herba Cynoglossi lanceolati 130 grams, Herba Anemones Hupehensis 150 grams, Herba Galii Bungei 120 grams, Flos Rhoeo discolorae 100 grams, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 100 grams, Cortex Meliosmatis rigidae Radicis 80 grams, Conyza canadensis (L.) Cronq. 80 grams, 60 grams, comb leaf, Radix Clematidis Henryi 70 grams, Radix Cynanchi Paniculati 80 grams, Cor Cervi grass 60 grams, Herba Violae japonicae 50 grams and 30 grams, Radix Glycyrrhizae, pulverize, cross 100 mesh sieves, then sucrose 600 grams is added, mixing, uniform distribution loads in 500 bags and get final product.

Experimental example

Diagnostic criteria

With reference to the guideline of clinical investigations of hyperlipemia " new Chinese medicine treatment " (Zheng Xiao cornel. study of tcm new drug clinical guidance principle [S]. Beijing: China Medical Science Press, 2002:85) and national dyslipidemia in 2007 visit and control " Blood Lipid Abnormality in Chinese Adults guideline of prevention and treatment " that countermeasure group writes and u.s. national cholesterol education program (NCEP) adult treatment expert group (ATP) is drafted about the guide (the 3rd edition) (ATP-III) reducing cholesterol control CHD.Patient surveys the one that blood fat meets following situation and can make a definite diagnosis: (1) cholesterol (TC) >=1.7mmol/L; Low density lipoprotein, LDL (LDL-C) >=3.6mmol/L; High density lipoprotein (HDL-C)≤1.0mmol/L.

Selector close standard of stating hyperlipidemia patient 120 example, wherein man 70 example, female 50 example, the age is 39 years old-63 years old, and the mean age is 46 years old.

Use powder obtained in embodiment to treat, wherein one day 2 times, oral one bag at every turn, treating 30 days is a course for the treatment of, treats 2 courses for the treatment of continuously.

Criterion of therapeutical effect

Reference " guideline of clinical investigations of new Chinese medicine treatment hyperlipemia " (Zheng Xiao cornel. study of tcm new drug clinical guidance principle [S]. Beijing: China Medical Science Press, 2002:85) draft:

Cure: after treatment, lipids detection recovers normal;

Effective; After treatment, lipids detection reaches following any 1 person, and namely TC declines >=20%, or TG declines >=40%, or HDL-C rising >=0.26mmol/L, or HDL-C/LDL-C >=20%;

Effective: after treatment, lipids detection reaches following any 1 person, i.e. TC decline <20%, or TG decline >=20%<40%, HDL-C rising >=0.104mmol/L<0.26mmol/L, or HDL-C/LDL-C >=10%<20%;

Invalid: after treatment, lipids detection is not improved or improves and do not reach effective standard person.

Result

Through treatment, find cholesterol (TC) <1.5mmol/L of all patients; Low density lipoprotein, LDL (LDL-C) <3.5mmol/L; High density lipoprotein (HDL-C) is 1.2-2.0mmol/L, all meets normal blood lipids index clinically.Therefore visible, all patients all meet the standard of healing.

Patient before the treatment after all promoting the circulation of blood, routine urinalysis and draw the inspection of kidney merit, after medication, every inspection is showed no obvious abnormalities, and patient does not also tell special discomfort.

Claims

1. treat the medicament of hyperlipemia for one kind, it is characterized in that, it is made up by weight of following bulk drugs: Radix Habenariae Dentatae 160 parts, fruitlet Herba lysimachiae capillipedis 130 parts, Lindera angustifolia Cheng 150 parts, Herba Cynoglossi lanceolati 130 parts, Herba Anemones Hupehensis 150 parts, Herba Galii Bungei 120 parts, Flos Rhoeo discolorae 100 parts, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 100 parts, Cortex Meliosmatis rigidae Radicis 80 parts, Conyza canadensis (L.) Cronq. 80 parts, 60 parts, comb leaf, Radix Clematidis Henryi 70 parts, Radix Cynanchi Paniculati 80 parts, Cor Cervi grass 60 parts, Herba Violae japonicae 50 parts and 30 parts, Radix Glycyrrhizae.

2. the medicament for the treatment of hyperlipemia according to claim 1, is characterized in that, described medicament can make tablet, dispersible tablet, rapidly dissolving tablet, powder or granule.