CN101904971B - Chinese medicinal composition for preventing and treating obesity and preparation thereof - Google Patents
Chinese medicinal composition for preventing and treating obesity and preparation thereof Download PDFInfo
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- CN101904971B CN101904971B CN2010101897637A CN201010189763A CN101904971B CN 101904971 B CN101904971 B CN 101904971B CN 2010101897637 A CN2010101897637 A CN 2010101897637A CN 201010189763 A CN201010189763 A CN 201010189763A CN 101904971 B CN101904971 B CN 101904971B
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Abstract
The invention provides a Chinese medicinal composition for preventing and treating obesity. The composition is an oral preparation which is prepared from medlar, lotus leaf, south dodder seed, tuber onion seed and cassia seed serving as raw material medicaments, and auxiliary materials by the conventional pharmaceutical process. The composition has the effects of removing dampness and relaxing the bowels, burning fat and expelling toxin, and warming yang and reinforcing the kidney so as to fulfill the aims of losing weight and slimming. Clinical data researches prove that the composition has obvious effect of preventing and controlling multiple kinds of obesity; meanwhile, the raw materials can be used as medicaments and foods, so the composition has good health-care effect on human bodies.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicine composition and preparation thereof that is used to prevent with treatment of obesity.
Technical background
Obesity is meant that obvious overweight and fat deposit to a certain degree is blocked up, is body fat, and especially triglyceride gathers a kind of state that too much causes.Owing to food intake too much or the change of organism metabolism cause body fat to gather too much causing excess weight to increase and cause human pathology, physiological change or hide.The body weight body weight 20% that is above standard is obesity.Obesity is divided into Simple Obesity, Secondary Obesity (being morbid oberity), subcutaneous obese type, internal organs obese type.Fat reason is extremely many, generally speaking is exactly to take in the too many and energy that consumes of intravital energy very little, thereby is stored in the body and forms with fatty form.Obesity can cause multiple disease, and as hypertension, coronary heart disease, angina pectoris, cerebrovascular disease, diabetes, hyperlipemia, hyperuricemia, fatty liver, sexual hypofunction etc. can also increase the probability that people suffer from malignant tumor.Women obesity can cause menoxenia and infertile; Children obesity can cause intelligence and sexual infantilism etc.
Nowadays Fei Pang patient is more and more, and the disease harm that brings thus also increases thereupon, and the generation of good multiple disease is all relevant in obesity.Treatment to obesity at present mainly contains following four kinds of modes:
(1) Diet Therapy: the control hyperphagia, nutrition should be appropriate; The absorption of control Animal fat, low salt diet is given up tobacco and wine, changes to eat a piece and the custom of sweet food.
(2) increase consumption: suitably increase quantity of motion, to increase the consumption of heat.
(3) Drug therapy: by medicine appetite-suppressing maincenter, dietary restriction, and by medicine catharsis and toxin expelling increasing excretion; Or increase the intestinal drainage by the diet crude fibre merely.
(4) instrument, attack a vital point, acupuncture and moxibustion therapy: by attack a vital point, the mode of acupuncture stimulates Excretory system to strengthen draining, to reach the purpose of fat-reducing.
Yet more or less there is defective in said method: the toxic and side effects of Drug therapy is big; Instrument, attack a vital point, acupuncture loses time, and also has the risk of communicate illness; Increase the motion and the amount of cutting down one's diet and be subjected to that the restriction of self-constraint force is difficult to adhere to etc.In a word, fat-reducing effect has uncertainty.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese crude drug that adopts integration of edible and medicinal herbs and be that feedstock production becomes is used to prevent Chinese medicine composition with treatment of obesity.
Chinese medicine composition of the present invention is to be raw material with Fructus Lycii, Folium Nelumbinis, Semen Cuscutae, Semen Allii Tuberosi, Semen Cassiae, the oral preparations that is prepared into by the common process and the adjuvant of pharmaceutics.
Fructus Lycii, sweet, flat, return liver, kidney channel, nourishing the liver and kidney, tonifying kidney and improving eyesight are the health care panacea.Generally be used for the treatment of various deficient diseases, and also have regulate immunity, antioxidation, defying age, protect the liver excellent functions such as hemopoietic, endocrine regulation, promotion reproduction, blood fat reducing, and be the dual-purpose product of life-prolonging medicinal food that prevail from ancient times to the present simply.
Folium Nelumbinis, bitter, puckery, flat, GUIXIN, liver, spleen channel, clearing away summer-heat and eliminating dampness, sending up the lucid YANG, hemostasis.Be generally used for diarrhea due to summer heat and dampness, dizzy, edema, haematemesis, epistaxis, have blood in stool, puerperal blood faints.The product that belong to integration of edible and medicinal herbs.
Semen Cuscutae, hot, sweet, flat, return liver, kidney channel, nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, make eye bright, antidiarrheal.Be generally used for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, frequent fetal movement, diarrhea due to hypofunction of the spleen.It can regulate immunity modern study, microcirculation improvement, and treatment endocrine and reproductive system disease protect the liver the anti-ageing effect of waiting for a long time.
Semen Allii Tuberosi, hot, sweet, warm, return liver, kidney channel, temperature compensation Liver and kidney, tonifying YANG controlling nocturnal emission with astringent drugs.Be used for impotence and seminal emission, soreness of waist and knee joint, enuresis frequent micturition, nebulousurine leukorrhagia.Modern study has antibiotic and antimutagenic effect.
Semen Cassiae, sweet, bitter, salty, be slightly cold, return liver, large intestine channel, clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.Be used for that the puckery pain of conjunctival congestion, the many tears of photophobia, headache are dizzy, poor vision, constipation.Modern study shows that this product has remarkable blood fat reducing hepatoprotective effect, regulates immunization, and hyperlipidemia is had fabulous rehabilitation effect.
The present invention selects medicine food homologous raw materials medicine Fructus Lycii, Folium Nelumbinis, Semen Cuscutae, Semen Allii Tuberosi, Semen Cassiae to make up, and the effect of each medicine is played altogether, and the mode of reinforcing the kidney, consume the fat toxin expelling by dampness removing relieving constipation, the fat toxin expelling that disappears, warming YANG reaches the purpose of weight-reducing.
By a large amount of tests and clinical summary, each crude drug of Chinese medicine composition of the present invention all has good effect to prevention and treatment of obesity in the scope of following weight portion:
5～15 parts of Fructus Lycii, 5～15 parts on Folium Nelumbinis, 2～10 parts of Semen Cuscutae, 2～6 parts of Semen Allii Tuberosi, 1～5 part of Semen Cassiae.
Optimum ratio is: 8～12 parts of Fructus Lycii, 8～12 parts on Folium Nelumbinis, 5～8 parts of Semen Cuscutae, 2～5 parts of Semen Allii Tuberosi, 2～5 parts of Semen Cassiaes.
Chinese medicine composition of the present invention can be prepared into various oral preparations by the common process and the adjuvant of pharmacy of Chinese materia medica.As capsule, tablet, granule, powder, pill (comprising the watered pill, honeyed pill, dragee, soft gelatin capsule, drop pill, enteric coated pill), microencapsulation and oral liquid.
Below by clinical data to medicine of the present invention to the prevention and the effect of treatment of obesity:
1. subjects and method
1.1 tried thing: capsule medicine of the present invention, every 0.25g is provided by Gansu Qingdai Chinese Herbal Medicine Beauty Research Co., Ltd..
1.2 study subject: select 2003～100 routine obese patients in 2005.Age between 13 years old～68 years old, male's 37 examples, women's 63 examples.
1.2.1 diagnostic criteria: body weight is above standard body weight 20% above person for fat.Body weight is above standard 20%～30% for slight fat, and 30%～50% is the moderate obesity, is the severe obesity greater than 50%.
1.3 instructions of taking:
Take this product 0.25g/ grain, every day three times, each 3, take 30 minutes ante cibum, 30 days courses of treatment, observed for 1～6 course of treatment.
2. observation index
Weight recovery to standard body weight is recovery from illness; The severe obesity is reduced to moderate, or moderate is reduced to the slight produce effects that is; Body weight is only fallen 3～10 jin of persons for effective; All the other are invalid.
3. result of the test
68 examples of fully recovering account for 68%; Produce effects 20 examples account for 20%; Effective 6 examples account for 6%; Invalid 6 examples account for 6%; Total effective rate accounts for 94%.
4. the analysis of statistical data
This is observed mainly based on body weight, but all experimenters health in various degree are healthy more, and the mental status is better, and obesity complication all makes moderate progress, eight enclosing (neck, arm, breast, abdomen, waist, buttocks, up and down strand enclose) has dwindling in various degree, does not also see untoward reaction and toxic and side effects.
5. conclusion
5.1 capsule of the present invention has the good curing effect to various obese patients.
5.2 capsule of the present invention has good health-care effect to human body.
5.3 capsule of the present invention has no adverse effects to human body.
5.4 capsule of the present invention does not have irritated reaction and other untoward reaction in the test-meal process.
The specific embodiment
The preparation of embodiment 1, tablet medicine of the present invention
Prescription: in weight portion: 15 parts of Fructus Lycii, 15 parts on Folium Nelumbinis, 10 parts of Semen Cuscutae, 6 parts of Semen Allii Tuberosi, 5 parts of Semen Cassiaes.
Technology: the common process and the adjuvant that prepare tablet by pharmacy of Chinese materia medica are prepared into tablet.
The preparation of embodiment 2, capsule medicine of the present invention
Prescription: in weight portion:
10 parts of Fructus Lycii, 10 parts on Folium Nelumbinis, 5 parts of Semen Cuscutae, 4 parts of Semen Allii Tuberosi, 1 part of Semen Cassiae.
Technology: the common process and the adjuvant that prepare capsule by pharmacy of Chinese materia medica are prepared into capsule.
The preparation of embodiment 3, powder agent medicine of the present invention
Prescription: in weight portion:
8 parts of Fructus Lycii, 8 parts on Folium Nelumbinis, 5 parts of Semen Cuscutae, 3 parts of Semen Allii Tuberosi, 2 parts of Semen Cassiaes.
Technology: the common process and the adjuvant that prepare powder by pharmacy of Chinese materia medica are prepared into powder.
The preparation of embodiment 4, granules medicine of the present invention
Prescription: in weight portion:
10 parts of Fructus Lycii, 8 parts on Folium Nelumbinis, 5 parts of Semen Cuscutae, 3 parts of Semen Allii Tuberosi, 1 part of Semen Cassiae.
Technology: the common process and the adjuvant that prepare granule by pharmacy of Chinese materia medica are prepared into granule.
The preparation of embodiment 5, drop pill medicine of the present invention
Prescription: in weight portion:
15 parts of Fructus Lycii, 10 parts on Folium Nelumbinis, 5 parts of Semen Cuscutae, 2 parts of Semen Allii Tuberosi, 3 parts of Semen Cassiaes.
Technology: the common process and the adjuvant that prepare drop pill by pharmacy of Chinese materia medica are prepared into drop pill.
The preparation of embodiment 6, watered pill medicine of the present invention
Prescription: in weight portion:
15 parts of Fructus Lycii, 8 parts on Folium Nelumbinis, 5 parts of Semen Cuscutae, 2 parts of Semen Allii Tuberosi, 1 part of Semen Cassiae.
Technology: the common process and the adjuvant that prepare watered pill by pharmacy of Chinese materia medica are prepared into watered pill.
The preparation of embodiment 7, honey pill agent medicine of the present invention
Prescription: in weight portion:
10 parts of Fructus Lycii, 15 parts on Folium Nelumbinis, 10 parts of Semen Cuscutae, 2 parts of Semen Allii Tuberosi, 5 parts of Semen Cassiaes.
Technology: the common process and the adjuvant that prepare honey pill agent by pharmacy of Chinese materia medica are prepared into honey pill agent.
The preparation of embodiment 8, oral medicine liquid of the present invention
Prescription: in weight portion:
10 parts of Fructus Lycii, 10 parts on Folium Nelumbinis, 2 parts of Semen Cuscutae, 2 parts of Semen Allii Tuberosi, 2 parts of Semen Cassiaes.
Technology: the common process and the adjuvant that prepare oral liquid by pharmacy of Chinese materia medica are prepared into oral liquid.
The preparation of embodiment 9, enteric coated pill medicine of the present invention
Prescription: in weight portion:
10 parts of Fructus Lycii, 8 parts on Folium Nelumbinis, 10 parts of Semen Cuscutae, 2 parts of Semen Allii Tuberosi, 3 parts of Semen Cassiaes.
Technology: the common process and the adjuvant that prepare enteric coated pill by pharmacy of Chinese materia medica are prepared into enteric coated pill.
The preparation of embodiment 10, microencapsulation agent medicine of the present invention
Prescription: in weight portion:
5 parts of Fructus Lycii, 5 parts on Folium Nelumbinis, 2 parts of Semen Cuscutae, 2 parts of Semen Allii Tuberosi, 1 part of Semen Cassiae.
Technology: the common process and the adjuvant that prepare microencapsulation by pharmacy of Chinese materia medica are prepared into microcapsule.
Claims (10)
1. one kind is used to prevent the Chinese medicine composition with treatment of obesity, is to be crude drug with Fructus Lycii, Folium Nelumbinis, Semen Cuscutae, Semen Allii Tuberosi, Semen Cassiae, the oral preparations that is prepared into by the common process and the adjuvant of pharmaceutics;
Described each raw material carries out proportioning with following weight parts:
5～15 parts of Fructus Lycii, 5～15 parts on Folium Nelumbinis, 2～10 parts of Semen Cuscutae, 1～6 part of Semen Allii Tuberosi, 1～5 part of Semen Cassiae.
2. be used to prevent the Chinese medicine composition with treatment of obesity according to claim 1, it is characterized in that: described each raw material medicines in portions by weight is as follows:
8～12 parts of Fructus Lycii, 8～12 parts on Folium Nelumbinis, 5～8 parts of Semen Cuscutae, 2～5 parts of Semen Allii Tuberosi, 2～5 parts of Semen Cassiaes.
3. be used to prevent the Chinese medicine composition with treatment of obesity according to claim 1, it is characterized in that: described preparation is a powder.
4. be used to prevent the Chinese medicine composition with treatment of obesity according to claim 1, it is characterized in that: described preparation is a pill.
5. as being used to prevent the Chinese medicine composition with treatment of obesity as described in the claim 4, it is characterized in that: described pill is the watered pill, honeyed pill, dragee, soft gelatin capsule, drop pill, enteric coated pill.
6. be used to prevent the Chinese medicine composition with treatment of obesity according to claim 1, it is characterized in that: described preparation is a tablet.
7. be used to prevent the Chinese medicine composition with treatment of obesity according to claim 1, it is characterized in that: described preparation is a capsule.
8. be used to prevent the Chinese medicine composition with treatment of obesity according to claim 1, it is characterized in that: described preparation is a granule.
9. be used to prevent the Chinese medicine composition with treatment of obesity according to claim 1, it is characterized in that: described preparation is an oral liquid.
10. be used to prevent the Chinese medicine composition with treatment of obesity according to claim 1, it is characterized in that: described preparation is a microencapsulation.
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| CN2010101897637A CN101904971B (en) | 2010-05-29 | 2010-05-29 | Chinese medicinal composition for preventing and treating obesity and preparation thereof |
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| CN2010101897637A CN101904971B (en) | 2010-05-29 | 2010-05-29 | Chinese medicinal composition for preventing and treating obesity and preparation thereof |
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| CN101904971B true CN101904971B (en) | 2011-11-02 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101480248A (en) * | 2008-05-16 | 2009-07-15 | 上海典智贸易有限公司 | Fat-reducing drink |
| CN101524441A (en) * | 2008-03-07 | 2009-09-09 | 天科仁祥技术（北京）有限责任公司 | Chinese medicinal composition for lipid-lowering and weight-losing and preparation method thereof |
-
2010
- 2010-05-29 CN CN2010101897637A patent/CN101904971B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101524441A (en) * | 2008-03-07 | 2009-09-09 | 天科仁祥技术（北京）有限责任公司 | Chinese medicinal composition for lipid-lowering and weight-losing and preparation method thereof |
| CN101480248A (en) * | 2008-05-16 | 2009-07-15 | 上海典智贸易有限公司 | Fat-reducing drink |
Non-Patent Citations (3)
| Title |
|---|
| 汪亮等.《中医药对肥胖症的防治及作用机制研究概述》.《辽宁中医学院学报》.2006,第8卷(第2期),129-130. * |
| 王玉英.《减肥药的开发现状及前景》.《中国中医药报》.2003, * |
| 谢楠等.《我国药茶的研究使用现状》.《中药材》.2000,第23卷(第1期),52-55. * |
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Effective date of registration: 20170224 Address after: The East, Peng Jia Ping Road No. B224 planning of Gansu Province, Lanzhou city Qilihe District 730050 West Road No. T226 planning Patentee after: Gansu indigo hundred years health management Limited by Share Ltd Address before: Tan Xiang Yan Chengguan District zhangsutan 730010 Gansu city of Lanzhou province No. 579 Patentee before: Lanzhou Guchi Biological Technology Co., Ltd. |