CN101524323A - Oral detergent - Google Patents

Oral detergent Download PDF

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Publication number
CN101524323A
CN101524323A CN200910136247A CN200910136247A CN101524323A CN 101524323 A CN101524323 A CN 101524323A CN 200910136247 A CN200910136247 A CN 200910136247A CN 200910136247 A CN200910136247 A CN 200910136247A CN 101524323 A CN101524323 A CN 101524323A
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CN
China
Prior art keywords
powder
baicalin
oral
carboxymethyl cellulose
bletillae
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Pending
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CN200910136247A
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Chinese (zh)
Inventor
修丹丹
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Individual
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Individual
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Priority to CN200910136247A priority Critical patent/CN101524323A/en
Publication of CN101524323A publication Critical patent/CN101524323A/en
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Abstract

A safe oral detergent for preventing and treating oral diseases comprises the following components in weight percentages: 5-10% of pearl powder, 0.5-5% of baicalin, 1-5% of bletilla hyacinthina gum powder, 1% of borneol, 20% of glycerol, 35% of calcium carbonate, 1.5% of sodium carboxymethyl cellulose, 0.05% of sodium benzoate and distilled water. The oral detergent can effectively prevent and treat the oral diseases, and the oral detergent is swallowable and safe without harmful chemical.

Description

A kind of cleaning agent for mouth cavity
Technical field
The present invention relates to a kind of cleaning supplies, especially relate to a kind of safe cleaning agent for mouth cavity of preventing and treating oral disease.
Background technology
Oral disease is a sickness rate disease with high among the crowd, and oral disease not only shows as alveolar abscess, gingivitis, periodontitis, pulpitis, dental caries, halitosis etc., not only influence the digestion of food, also may become infection focus, cause or aggravate human body such as diseases such as subacute bacillary intimitis, rheumatic arthritis, glomerulonephritis, iritis, cyclitis, hypertension, diabetes.How treatment becomes the problem that current people are concerned about for oral disease provides preferably.
Along with China's rapid development of economy, people's material and cultural life also improve constantly, people more and more pay attention to oral health and health care, and various dental care products also arise at the historic moment, and comprise sterilizing oral agent, antozostomatic, tooth cleaning agent and artificial tooth cleaning agent etc.The sterilizing oral agent has gargarism or collutory, and antozostomatic has rinse water, solid, paste antozostomatic and chewing gum etc.Tooth cleaning agent comprises cleaning of teeth liquid, solid dentifrice and toothpaste, and artificial tooth cleaning agent has the foaming tablet and scrubs with two kinds of cleaning agent.Numerous in the market cleaning agent for mouth cavity are the requirement of satisfying people's tooth-whitening, antiacid, the fresh breath of desensitization, mothproof health care, all contain harmful chemical substances such as antibiotic, fluoride and surfactant, but always do not make people not satisfied because of effect is good enough.Therefore be necessary the cleaning agent for mouth cavity articles for use of prior art are improved, for people provide the safe cleaning agent for mouth cavity of preventing and treating oral disease significant.
Summary of the invention
The purpose of this invention is to provide a kind of safe cleaning agent for mouth cavity of preventing and treating oral disease and preparation method thereof.
Purpose of the present invention can be achieved through the following technical solutions, the percetage by weight of its each component is: Margarita powder 5~10, baicalin 0.5~5, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder 1~5, Borneolum Syntheticum 1, glycerol 20, calcium carbonate 35, sodium carboxymethyl cellulose 1.5, sodium benzoate 0.05, all the other are distilled water.
Preparation technology of the present invention comprises the steps:
(1) Margarita powder is broken into fine powder and crosses 200 mesh sieves, and is standby.
(2) the Radix Scutellariae coarse powder boils (each 1h) 2 times with decocting, filters; Filtrate is transferred pH to 1~2,80 ℃ following insulation 30min with dilute hydrochloric acid, and centrifugal, precipitation adds suitable quantity of water, with 40gL -1Sodium hydroxide solution is transferred pH to 7, adds an amount of ethanol, filters; Filtrate is transferred pH to 1~2,80 ℃ following insulation 30min with dilute hydrochloric acid, and is centrifugal; The precipitation washing, 50% ethanol is washed, and 95% ethanol is washed, and gets baicalin.
(3) get Pseudobulbus Bletillae (Rhizoma Bletillae) tuber and chop up, pulverize, adding distil water (consumption is about 15 times~20 times of medical material) soaks 1h~2h, heats 90 ℃~95 ℃, constantly stirs, and filters filtrate for later use.Medicinal residues soak 2 times again, and each water consumption is 8 times~10 times of medical material amount, heats 90 ℃~95 ℃, filters.Merge 3 filtrates and be condensed into the thick paste shape, add 95% ethanol after the cooling, stir, promptly separate out a large amount of flocculent deposit liquid, leave standstill, vacuum filtration is dried to doing, and porphyrize promptly gets Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder slightly.
(4) take by weighing Margarita powder, baicalin, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder, Borneolum Syntheticum, glycerol, calcium carbonate, sodium carboxymethyl cellulose, sodium benzoate by prescription;
(5) Borneolum Syntheticum is fine ground, heated and stirred makes dissolving fully in the adding glycerol, and is standby;
(6) mix in the glycerite adding mixer with distilled water, above-mentioned Borneolum Syntheticum again, adding sodium carboxymethyl cellulose then is stirred well to sodium carboxymethyl cellulose and dissolves fully, add calcium carbonate, Margarita powder, baicalin, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder, sodium benzoate more successively, stir and make it and outgas last canned one-tenth finished product.
Cold in nature, the sweet-salty of Chinese medicine Margarita powder is gone into the cardiopulmonary warp, the tool tranquillizing and allaying excitement, and skin ulcer is held back in heat clearing away, the effect of granulation promoting detoxifcation; Baicalin has heat clearing and damp drying, effects such as eliminating fire and detoxication, and modern pharmacological research proves, that baicalin has is antibacterial, antiviral, heat clearing away, blood pressure lowering, calmness, diuresis, function of gallbladder promoting, antiinflammatory, antiallergic action isoreactivity.The Pseudobulbus Bletillae (Rhizoma Bletillae) is used as Chinese medicine, has functions such as the skin ulcer of holding back hemostasis, tonifying the lung, detumescence and promoting granulation, and its effective ingredient Pseudobulbus Bletillae (Rhizoma Bletillae) glue has convergence, hemostasis, promote wound healing, suppress Streptococcus mutans, thickening, suspend, preserve moisture and help function such as emulsifying.Borneolum Syntheticum has the effect of the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain; can promote the Transdermal absorption of medicine; traditional Cheng Fangzhong such as FUFANG DANSHEN DIWAN, SUXIAO JIUXIN WAN, cow-bezoar bolus for resurrection; utilize the effect of Borneolum Syntheticum " fragrance is walked to scurry; priming is up ", " a little less than the gesture of walking alone then; assistant makes then meritorious " more, increased the therapeutic effect of other medicines as guiding drug.Calcium carbonate in the cleaning agent for mouth cavity of the present invention, sodium carboxymethyl cellulose make antibacterial, virus, food debris and dirt reach the purpose of thorough cleaning oral cavity through the discharge of gargling.
Advantage of the present invention is that Margarita powder in the cleaning agent for mouth cavity, baicalin, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder, Borneolum Syntheticum rational formula have detumescence and promoting granulation, healing up sore and relieving pain, inhibiting bacteria and diminishing inflammation, detoxifcation hemostatic effect, can effectively prevent and treat oral disease; This cleaning agent for mouth cavity of what is more important does not have chemical harmful substance, can swallow, safety is good.
The specific embodiment
By following specific embodiment, can further understand the present invention, but protection scope of the present invention is not limited to this.
One one kinds of safe cleaning agent for mouth cavity of preventing and treating oral disease of embodiment, the percetage by weight of its each component is: Margarita powder 5, baicalin 0.5, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder 1, Borneolum Syntheticum 1, glycerol 20, calcium carbonate 35, sodium carboxymethyl cellulose 1.5, sodium benzoate 0.05, all the other are distilled water.
Preparation technology of the present invention comprises the steps:
(1) Margarita powder is broken into fine powder and crosses 200 mesh sieves, and is standby.
(2) the Radix Scutellariae coarse powder boils (each 1h) 2 times with decocting, filters; Filtrate is transferred pH to 1~2,80 ℃ following insulation 30min with dilute hydrochloric acid, and centrifugal, precipitation adds suitable quantity of water, with 40gL -1Sodium hydroxide solution is transferred pH to 7, adds an amount of ethanol, filters; Filtrate is transferred pH to 1~2,80 ℃ following insulation 30min with dilute hydrochloric acid, and is centrifugal; The precipitation washing, 50% ethanol is washed, and 95% ethanol is washed, and gets baicalin.
(3) get Pseudobulbus Bletillae (Rhizoma Bletillae) tuber and chop up, pulverize, adding distil water (consumption is about 15 times~20 times of medical material) soaks 1h~2h, heats 90 ℃~95 ℃, constantly stirs, and filters filtrate for later use.Medicinal residues soak 2 times again, and each water consumption is 8 times~10 times of medical material amount, heats 90 ℃~95 ℃, filters.Merge 3 filtrates and be condensed into the thick paste shape, add 95% ethanol after the cooling, stir, promptly separate out a large amount of flocculent deposit liquid, leave standstill, vacuum filtration is dried to doing, and porphyrize promptly gets Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder slightly.
(4) take by weighing Margarita powder, baicalin, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder, Borneolum Syntheticum, glycerol, calcium carbonate, sodium carboxymethyl cellulose, sodium benzoate by prescription;
(5) Borneolum Syntheticum is fine ground, heated and stirred makes dissolving fully in the adding glycerol, and is standby;
(6) mix in the glycerite adding mixer with distilled water, above-mentioned Borneolum Syntheticum again, adding sodium carboxymethyl cellulose then is stirred well to sodium carboxymethyl cellulose and dissolves fully, add calcium carbonate, Margarita powder, baicalin, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder, sodium benzoate more successively, stir and make it and outgas last canned one-tenth finished product.
21 kinds of safe cleaning agent for mouth cavity of preventing and treating oral disease of embodiment, the percetage by weight of its each component is: Margarita powder 8, baicalin 3, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder 3, Borneolum Syntheticum 1, glycerol 20, calcium carbonate 35, sodium carboxymethyl cellulose 1.5, sodium benzoate 0.05, all the other are distilled water.
Preparation technology of the present invention comprises the steps:
(1) Margarita powder is broken into fine powder and crosses 200 mesh sieves, and is standby.
(2) the Radix Scutellariae coarse powder boils (each 1h) 2 times with decocting, filters; Filtrate is transferred pH to 1~2,80 ℃ following insulation 30min with dilute hydrochloric acid, and centrifugal, precipitation adds suitable quantity of water, with 40gL -1Sodium hydroxide solution is transferred pH to 7, adds an amount of ethanol, filters; Filtrate is transferred pH to 1~2,80 ℃ following insulation 30min with dilute hydrochloric acid, and is centrifugal; The precipitation washing, 50% ethanol is washed, and 95% ethanol is washed, and gets baicalin.
(3) get Pseudobulbus Bletillae (Rhizoma Bletillae) tuber and chop up, pulverize, adding distil water (consumption is about 15 times~20 times of medical material) soaks 1h~2h, heats 90 ℃~95 ℃, constantly stirs, and filters filtrate for later use.Medicinal residues soak 2 times again, and each water consumption is 8 times~10 times of medical material amount, heats 90 ℃~95 ℃, filters.Merge 3 filtrates and be condensed into the thick paste shape, add 95% ethanol after the cooling, stir, promptly separate out a large amount of flocculent deposit liquid, leave standstill, vacuum filtration is dried to doing, and porphyrize promptly gets Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder slightly.
(4) take by weighing Margarita powder, baicalin, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder, Borneolum Syntheticum, glycerol, calcium carbonate, sodium carboxymethyl cellulose, sodium benzoate by prescription;
(5) Borneolum Syntheticum is fine ground, heated and stirred makes dissolving fully in the adding glycerol, and is standby;
(6) mix in the glycerite adding mixer with distilled water, above-mentioned Borneolum Syntheticum again, adding sodium carboxymethyl cellulose then is stirred well to sodium carboxymethyl cellulose and dissolves fully, add calcium carbonate, Margarita powder, baicalin, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder, sodium benzoate more successively, stir and make it and outgas last canned one-tenth finished product.
31 kinds of safe cleaning agent for mouth cavity of preventing and treating oral disease of embodiment, the percetage by weight of its each component is: Margarita powder 10, baicalin 5, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder 5, Borneolum Syntheticum 1, glycerol 20, calcium carbonate 35, sodium carboxymethyl cellulose 1.5, sodium benzoate 0.05, all the other are distilled water.
Preparation technology of the present invention comprises the steps:
(1) Margarita powder is broken into fine powder and crosses 200 mesh sieves, and is standby.
(2) the Radix Scutellariae coarse powder boils (each 1h) 2 times with decocting, filters; Filtrate is transferred pH to 1~2,80 ℃ following insulation 30min with dilute hydrochloric acid, and centrifugal, precipitation adds suitable quantity of water, with 40gL -1Sodium hydroxide solution is transferred pH to 7, adds an amount of ethanol, filters; Filtrate is transferred pH to 1~2,80 ℃ following insulation 30min with dilute hydrochloric acid, and is centrifugal; The precipitation washing, 50% ethanol is washed, and 95% ethanol is washed, and gets baicalin.
(3) get Pseudobulbus Bletillae (Rhizoma Bletillae) tuber and chop up, pulverize, adding distil water (consumption is about 15 times~20 times of medical material) soaks 1h~2h, heats 90 ℃~95 ℃, constantly stirs, and filters filtrate for later use.Medicinal residues soak 2 times again, and each water consumption is 8 times~10 times of medical material amount, heats 90 ℃~95 ℃, filters.Merge 3 filtrates and be condensed into the thick paste shape, add 95% ethanol after the cooling, stir, promptly separate out a large amount of flocculent deposit liquid, leave standstill, vacuum filtration is dried to doing, and porphyrize promptly gets Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder slightly.
(4) take by weighing Margarita powder, baicalin, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder, Borneolum Syntheticum, glycerol, calcium carbonate, sodium carboxymethyl cellulose, sodium benzoate by prescription;
(5) Borneolum Syntheticum is fine ground, heated and stirred makes dissolving fully in the adding glycerol, and is standby;
(6) mix in the glycerite adding mixer with distilled water, above-mentioned Borneolum Syntheticum again, adding sodium carboxymethyl cellulose then is stirred well to sodium carboxymethyl cellulose and dissolves fully, add calcium carbonate, Margarita powder, baicalin, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder, sodium benzoate more successively, stir and make it and outgas last canned one-tenth finished product.

Claims (1)

1. cleaning agent for mouth cavity, it is characterized in that, the percetage by weight of each component is: Margarita powder 5~10, baicalin 0.5~5, Pseudobulbus Bletillae (Rhizoma Bletillae) rubber powder 1~5, Borneolum Syntheticum 1, glycerol 20, calcium carbonate 35, sodium carboxymethyl cellulose 1.5, sodium benzoate 0.05, all the other are distilled water.
CN200910136247A 2009-05-04 2009-05-04 Oral detergent Pending CN101524323A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200910136247A CN101524323A (en) 2009-05-04 2009-05-04 Oral detergent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN200910136247A CN101524323A (en) 2009-05-04 2009-05-04 Oral detergent

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CN101524323A true CN101524323A (en) 2009-09-09

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CN200910136247A Pending CN101524323A (en) 2009-05-04 2009-05-04 Oral detergent

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103520011A (en) * 2013-10-18 2014-01-22 柳州两面针股份有限公司 Application of tetrahydropalmatine and baicalin in preparing oral care products
CN104906023A (en) * 2015-04-24 2015-09-16 南通蛇类治疗研究所 Oral cavity tooth cleaner

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103520011A (en) * 2013-10-18 2014-01-22 柳州两面针股份有限公司 Application of tetrahydropalmatine and baicalin in preparing oral care products
CN104906023A (en) * 2015-04-24 2015-09-16 南通蛇类治疗研究所 Oral cavity tooth cleaner

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Addressee: Xiu Dandan

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Application publication date: 20090909