CN101508994A - 重组人干扰素a2b的基因优化及高效表达 - Google Patents
重组人干扰素a2b的基因优化及高效表达 Download PDFInfo
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- CN101508994A CN101508994A CNA2009100777743A CN200910077774A CN101508994A CN 101508994 A CN101508994 A CN 101508994A CN A2009100777743 A CNA2009100777743 A CN A2009100777743A CN 200910077774 A CN200910077774 A CN 200910077774A CN 101508994 A CN101508994 A CN 101508994A
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- human interferon
- recombinant human
- ifn
- expression
- interferon alpha
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
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引物名称 | 引物序列 |
IFN-a2b-F01 | 5’-cgggatcccatATGTGCGATCTGCC-3’ |
IFN-a2b-F02 | 5’-GCAGACCCATAGCCTGGGCAGCCGTCGTACCCTGATGCTGCTGGCGCAG-3’ |
IFN-a2b-F03 | 5’-ATGCGCCGTATTAGCCTGTTTAGCTGCCTGAAAGATCGCCATGATTTTGG-3’ |
IFN-a2b-F04 | 5’-TTTCCCGCAGGAAGAATTTGGCAACCAGTTTCAGAAAGCGGAAACCATT-3’ |
IFN-a2b-F05 | 5’-CCGGTGCTGCATGAGATGATCCAGCAGATTTTCAATCTGTTTAGCACGAA-3’ |
IFN-a2b-F06 | 5’-AGATAGCAGCGCCGCCTGGGATGAAACCCTGCTGGATAAATTTTATACC-3’ |
IFN-a2b-F07 | 5’-GAACTGTATCAGCAGCTGAACGATCTGGAAGCGTGTGTGATTCAGGGTGT-3’ |
IFN-a2b-F08 | 5’-TGGCGTGACGGAGACCCCGCTGATGAAAGAAGATAGCATCCTGGCGGTG-3’ |
IFN-a2b-F09 | 5’-CGTAAATATTTCCAGCGCATTACCCTGTACCTGAAAGAAAAGAAATATAG-3’ |
IFN-a2b-F10 | 5’-CCCGTGTGCCTGGGAAGTTGTGCGTGCGGAGATTATGCGCAGCTTTAGC-3’ |
IFN-a2b-F11 | 5’-CTGAGCACCAATCTGCAGGAAAGCCTGCGTAGCAAAGAATAATgaattcc-3’ |
IFN-a2b-R01 | 5’-GGAATTCATTATTCTTTGCTACGCA-3’ |
IFN-a2b-R02 | 5’-GGCTTTCCTGCAGATTGGTGCTCAGGCTAAAGCTGCGCATAATCTCCGC-3’ |
IFN-a2b-R03 | 5’-ACGCACAACTTCCCAGGCACACGGGCTATATTTCTTTTCTTTCAGGTACA-3’ |
IFN-a2b-R04 | 5’-GGGTAATGCGCTGGAAATATTTACGCACCGCCAGGATGCTATCTTCTTT-3’ |
IFN-a2b-R05 | 5’-CATCAGCGGGGTCTCCGTCACGCCAACACCCTGAATCACACACGCTTCCA-3’ |
IFN-a2b-R06 | 5’-GATCGTTCAGCTGCTGATACAGTTCGGTATAAAATTTATCCAGCAGGGT-3’ |
IFN-a2b-R07 | 5’-TTCATCCCAGGCGGCGCTGCTATCTTTCGTGCTAAACAGATTGAAAATCT-3’ |
IFN-a2b-R08 | 5’-GCTGGATCATCTCATGCAGCACCGGAATGGTTTCCGCTTTCTGAAACTG-3’ |
IFN-a2b-R09 | 5’-GTTGCCAAATTCTTCCTGCGGGAAACCAAAATCATGGCGATCTTTCAGGC-3’ |
IFN-a2b-R10 | 5’-AGCTAAACAGGCTAATACGGCGCATCTGCGCCAGCAGCATCAGGGTACG-3’ |
IFN-a2b-R11 | 5’-ACGGCTGCCCAGGCTATGGGTCTGCGGCAGATCGCACATATGGGATCCCG-3’ |
hIFN-a2b-F01 | 5’-GGAATTCCATAtgtgtgacctgccgcagacccactctctgggttctcgtcgtaccctga-3’ |
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN2009100777743A CN101508994B (zh) | 2009-02-19 | 2009-02-19 | 重组人干扰素α2b的基因优化及高效表达 |
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CN2009100777743A CN101508994B (zh) | 2009-02-19 | 2009-02-19 | 重组人干扰素α2b的基因优化及高效表达 |
Publications (2)
Publication Number | Publication Date |
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CN101508994A true CN101508994A (zh) | 2009-08-19 |
CN101508994B CN101508994B (zh) | 2011-01-05 |
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CN2009100777743A Active CN101508994B (zh) | 2009-02-19 | 2009-02-19 | 重组人干扰素α2b的基因优化及高效表达 |
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CN (1) | CN101508994B (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107384934A (zh) * | 2017-08-18 | 2017-11-24 | 安徽安科生物工程(集团)股份有限公司 | 重组人干扰素α2b的制备方法 |
CN111996225A (zh) * | 2020-09-18 | 2020-11-27 | 深圳科兴药业有限公司 | 一种利用微生物生产高活性重组人干扰素α2b的发酵方法 |
-
2009
- 2009-02-19 CN CN2009100777743A patent/CN101508994B/zh active Active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107384934A (zh) * | 2017-08-18 | 2017-11-24 | 安徽安科生物工程(集团)股份有限公司 | 重组人干扰素α2b的制备方法 |
CN111996225A (zh) * | 2020-09-18 | 2020-11-27 | 深圳科兴药业有限公司 | 一种利用微生物生产高活性重组人干扰素α2b的发酵方法 |
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Publication number | Publication date |
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CN101508994B (zh) | 2011-01-05 |
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Address after: 3 building, No. 6, Jingdong street, Yizhuang economic and Technological Development Zone, Beijing 100176, China Patentee after: BEIJING KAWIN TECHNOLOGY SHARE-HOLDING Co.,Ltd. Patentee after: Beijing Furui Tiancheng Biotechnology Co.,Ltd. Address before: 3 building, No. 6, Jingdong street, Beijing economic and Technological Development Zone, 100176 Patentee before: BEIJING KAWIN TECHNOLOGY SHARE-HOLDING Co.,Ltd. Patentee before: BEIJING KAWIN BIOTECHNOLOGY Co.,Ltd. |
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Effective date of registration: 20150211 Address after: 3 building, No. 6, Jingdong street, Yizhuang economic and Technological Development Zone, Beijing 100176, China Patentee after: BEIJING KAWIN TECHNOLOGY SHARE-HOLDING Co.,Ltd. Address before: 3 building, No. 6, Jingdong street, Yizhuang economic and Technological Development Zone, Beijing 100176, China Patentee before: BEIJING KAWIN TECHNOLOGY SHARE-HOLDING Co.,Ltd. Patentee before: Beijing Furui Tiancheng Biotechnology Co.,Ltd. |