CN101507822B - 皮肤瘢痕形成的减少 - Google Patents

皮肤瘢痕形成的减少 Download PDF

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Publication number
CN101507822B
CN101507822B CN2009101287188A CN200910128718A CN101507822B CN 101507822 B CN101507822 B CN 101507822B CN 2009101287188 A CN2009101287188 A CN 2009101287188A CN 200910128718 A CN200910128718 A CN 200910128718A CN 101507822 B CN101507822 B CN 101507822B
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China
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rad
waf1
cip1
cell
wound
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Expired - Fee Related
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CN2009101287188A
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English (en)
Chinese (zh)
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CN101507822A (zh
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D·古
M·泽佩达
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Canji Inc
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Canji Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN2009101287188A 2003-11-24 2004-11-23 皮肤瘢痕形成的减少 Expired - Fee Related CN101507822B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52499303P 2003-11-24 2003-11-24
US60/524993 2003-11-24

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB2004800406132A Division CN100482674C (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

Publications (2)

Publication Number Publication Date
CN101507822A CN101507822A (zh) 2009-08-19
CN101507822B true CN101507822B (zh) 2012-06-06

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CN2009101287188A Expired - Fee Related CN101507822B (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少
CNB2004800406132A Expired - Fee Related CN100482674C (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

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CNB2004800406132A Expired - Fee Related CN100482674C (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

Country Status (13)

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US (3) US7465442B2 (enExample)
EP (1) EP1692154A4 (enExample)
JP (2) JP4842139B2 (enExample)
KR (1) KR101167330B1 (enExample)
CN (2) CN101507822B (enExample)
AU (1) AU2004293474B2 (enExample)
BR (1) BRPI0416920A (enExample)
CA (1) CA2546287C (enExample)
IL (1) IL175603A (enExample)
NO (1) NO20062978L (enExample)
NZ (1) NZ546983A (enExample)
WO (1) WO2005051971A1 (enExample)
ZA (1) ZA200604147B (enExample)

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EP1692154A4 (en) * 2003-11-24 2009-07-08 Canji Inc REDUCTION OF SKIN TEMPERING
CN103271761B (zh) 2008-01-14 2015-10-28 康文图斯整形外科公司 用于骨折修补的装置和方法
CA2753338A1 (en) 2008-09-22 2010-03-25 Rxi Pharmaceuticals Corporation Neutral nanotransporters
US20110178520A1 (en) 2010-01-15 2011-07-21 Kyle Taylor Rotary-rigid orthopaedic rod
AU2011207550B2 (en) 2010-01-20 2016-03-10 Conventus Orthopaedics, Inc. Apparatus and methods for bone access and cavity preparation
CN105361942B (zh) 2010-03-08 2018-01-09 康文图斯整形外科公司 用于固定骨植入物的装置及方法
AU2011232365A1 (en) 2010-03-24 2012-10-25 Rxi Pharmaceuticals Corporation RNA interference in dermal and fibrotic indications
JP6883987B2 (ja) * 2013-12-04 2021-06-09 フィオ ファーマシューティカルズ コーポレーションPhio Pharmaceuticals Corp. 化学修飾されたオリゴヌクレオチドを利用する創傷治癒の処置のための方法
CN105939677A (zh) 2013-12-12 2016-09-14 康文图斯整形外科公司 组织移位工具和方法
KR102506169B1 (ko) 2014-09-05 2023-03-08 피오 파마슈티칼스 코프. Tyr 또는 mmp1을 표적화하는 핵산을 사용한 노화 및 피부 장애의 치료 방법
CA3021073A1 (en) * 2016-04-14 2017-10-19 Trizell Ltd. Viral vector stabilization
US10918426B2 (en) 2017-07-04 2021-02-16 Conventus Orthopaedics, Inc. Apparatus and methods for treatment of a bone

Citations (1)

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US20020111304A1 (en) * 2000-12-01 2002-08-15 Andrius Kazlauskas Methods and compositions for treating fibrotic diseases

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AU2004293474B2 (en) 2010-12-23
US20050271623A1 (en) 2005-12-08
IL175603A0 (en) 2006-09-05
NO20062978L (no) 2006-06-26
AU2004293474A1 (en) 2005-06-09
ZA200604147B (en) 2007-11-28
US20110129534A1 (en) 2011-06-02
EP1692154A1 (en) 2006-08-23
EP1692154A4 (en) 2009-07-08
US20090142397A1 (en) 2009-06-04
BRPI0416920A (pt) 2007-01-23
JP2007512377A (ja) 2007-05-17
CA2546287C (en) 2014-04-22
CA2546287A1 (en) 2005-06-09
KR20060127414A (ko) 2006-12-12
CN101507822A (zh) 2009-08-19
US8329671B2 (en) 2012-12-11
CN1906205A (zh) 2007-01-31
JP2011207912A (ja) 2011-10-20
CN100482674C (zh) 2009-04-29
WO2005051971A1 (en) 2005-06-09
KR101167330B1 (ko) 2012-07-23
NZ546983A (en) 2009-05-31
US7465442B2 (en) 2008-12-16
JP4842139B2 (ja) 2011-12-21
IL175603A (en) 2011-02-28

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Granted publication date: 20120606

Termination date: 20161123