CN101504419A - Blood analysis system used for high-communicable disease - Google Patents

Blood analysis system used for high-communicable disease Download PDF

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Publication number
CN101504419A
CN101504419A CNA2009101059124A CN200910105912A CN101504419A CN 101504419 A CN101504419 A CN 101504419A CN A2009101059124 A CNA2009101059124 A CN A2009101059124A CN 200910105912 A CN200910105912 A CN 200910105912A CN 101504419 A CN101504419 A CN 101504419A
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analysis system
measurement module
blood analysis
measurement
valve
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CNA2009101059124A
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CN101504419B (en
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张会生
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Shenzhen University
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Shenzhen University
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Abstract

In order to solve the technical problems of low biological safety and poor real-time property of the prior blood analysis system for highly contagious diseases, the invention provides a blood analysis system used for the highly contagious diseases. The blood analysis system comprises a sample feeding mechanism, a measurement and analysis module, a waste liquid treatment device and a liquid channel system, wherein the measurement and analysis module consists of an electrolyte measurement module and a biochemical measurement module; the electrolyte measurement module is connected with the sample feeding mechanism and connected to the waste liquid treatment device by a peristaltic pump; the biochemical measurement module consists of a reagent container, a reagent valve, the peristaltic pump, a sampling valve, a reaction pipe and a detector which are connected in turn; the sampling valve is connected with the sample feeding mechanism; and the detector is connected with the waste liquid treatment device. The blood analysis system has the advantages that: the system has high biological safety and strong real-time property, makes all measurement items carry out in an enclosed pipe, has no separate injection in the analysis process, is provided with a waste liquid sterilizing device, has strong real-time property, integrates the analysis of electrolyte, biochemical and immune items, has small volume and can be used in a ward.

Description

A kind of blood analysis system that is used for the highly infective disease
Technical field
The present invention relates to a kind of blood analysis system, relate to a kind of blood analysis system that is used for the highly infective disease particularly.
Background technology
The highly infective disease is the significant problem that the 21 century mankind face, the important topic that public health security has become the whole society and faced.Highly infective disease patient's blood analysis is diagnosed the illness to the clinician and implements to treat most important.Because the singularity of highly infective disease has proposed new higher requirement to the clinical blood analytical instrument: biological safety is high and real-time.But present conventional blood analysis system is in the requirement that all can not satisfy clinical blood analysis to highly infective disease patient aspect biological safety and the real-time.Be embodied in:
1, biological safety is low.Biological safety is meant sample pre-treatments, measure in, aftertreatment can not bring cross-infection to operating personnel.But present clinical blood analytical approach and instrument to sample pre-treatments, measure in, all might cause infection in the process of aftertreatment to the operator.Present measuring process generally is divided into following 5 processes:
1. be by delivering to HC clinical laboratory after medical worker's blood drawing.
2. checked operation person carries out centrifugally to the whole blood in the sampling container, obtains serum.
3. then with serum secondary dispensing in the used measuring cup of instrument, measuring cup is moved on on the instrument measure again; Or directly the former test tube after centrifugal is directly moved on to (so-called former test tube application of sample) on the instrument.
4. surveying instrument by the method for chemistry or physics, obtains measurement result with serum dispensing or suck measuring cell once more at last.
5. will measure waste liquid and be discharged to waste liquid bottle or waste liquid barrel, after waste liquid bottle or waste liquid barrel are full, handle again.
3. the step of sample pretreatment process and the 4. step in the sample measurement process, all to carry out the secondary dispensing to sample, secondary dispensing process can produce gasoloid, and these gasoloids can be propagated in air, are easy to cause the superinfection of pathogeny in clinical laboratory; 5. in the step of sample aftertreatment, a waste liquid Sheng year container is open at present, and the refuse after the measurement does not possess disinfectant measure.
2, real-time is not strong.Real-time is meant from taking sample will lack to the time that obtains measurement result, can gain time for the doctor rescues the patient like this.Cause not strong former reason two aspects of blood analysis real-time to cause at present: the one, present analytic process all is sample to be taken HC clinical laboratory check from the ward, ward and center clinical laboratory distance at large hospital are far away, and sample presentation can take the long period; The 2nd, measuring polytype project is to need different custom-built machines, detect electrolyte project, biochemical project, the desired appliance requires 2-3 of immune project kind instrument as present hospital, need the time that sample is assigned on the different analytical instrument like this, setup time is longer.For reducing the sample presentation shared time of process, make things convenient for the clinician to obtain measurement result as early as possible, be beneficial to diagnosis and treatment, clinical examination circle of developed country, proposed the method for POCT (point of care test POCT), promptly the blood samples of patients sample has been tested at one's side or in the nearer zone and can obtain the result very soon patient.
Summary of the invention
Purpose of the present invention is low at highly infective disease biological safety for solving existing blood analysis system, and the technical matters that real-time is not strong provides a kind of blood analysis system that is used for the highly infective disease.
The present invention realizes that the technical scheme that goal of the invention adopts is, a kind of highly infective disease blood analysis system, comprise sample introduction mechanism, the Measurement and analysis module, liquid waste treating apparatus and liquid-way system, described Measurement and analysis module is made up of electrolyte measurement module and biochemical measurement module, described electrolyte measurement module connects sample introduction mechanism and inserts liquid waste treating apparatus through peristaltic pump, described biochemical measurement module is by reagent container, the reagent valve, peristaltic pump, sampling valve, reacting pipe and detecting device connect to form successively, described sampling valve connects sample introduction mechanism, and described detecting device connects liquid waste treating apparatus.
Better, described sample introduction mechanism connects the sampling valve of electrolyte measurement module and biochemical measurement module by T-valve.Described reagent valve adopts the hyperchannel cross-over valve, can carry out multiselect one commutation conversion to plurality of reagents.
For improving biological safety, described liquid waste treating apparatus adopts ozonization plant, and waste liquid is stored in the flexible containers, so that destroy.
The invention has the beneficial effects as follows, the biological safety height, the measurement of all items is all carried out in the pipeline of sealing, does not have the sample dispensing in the analytic process, can not produce gasoloid; Have the waste liquid chlorination equipment, can sterilize in real time, the disposable use of packing container can be disinfected on the spot;
Real-time, the analysis three of electrolyte project, biochemical project, immune project (employing immunoturbidimetry) is combined into one, realize by an instrument, can measure electrolyte project specific in the blood, biochemical project and immune project simultaneously, analysis time is short, easy and simple to handle, can provide data timely for the clinician; The instrument liquid flow path is simple, and the instrument volume is little, meets the POCT notion, can installation and checkout in the isolation ward zone.
Description of drawings
Fig. 1, the structural representation of blood analysis system of the present invention.
Among the figure, 1, sample introduction mechanism, 2, T-valve, 3, the ISE measurement module, 4, peristaltic pump, 5, liquid waste treating apparatus, 6, reagent container, 7, the hyperchannel cross-over valve, 8, peristaltic pump, 9 sampling valves, 10, reacting pipe, 11, photoelectric detector.
Embodiment
Referring to accompanying drawing 1, a kind of blood analysis system that is used for the highly infective disease, sample introduction mechanism 1, T-valve 2, ISE electrolyte measurement module 3 and peristaltic pump 4 are formed the electrolyte measurement module, peristaltic pump 4 connects liquid waste treating apparatus 5, reagent container 6, hyperchannel cross-over valve 7, peristaltic pump 8, sampling valve 9, reacting pipe 10 and photoelectric detector 11 connect to form biochemical measurement module successively, described sampling valve 9 is communicated with sample introduction mechanism 1 by T-valve 2, described photoelectric detector 11 connects liquid waste treating apparatus 5, described liquid waste treating apparatus 5 is an ozonization plant, and waste liquid is stored in the flexible containers.
The Measurement and analysis process of blood analysis system of the present invention is as follows:
1, electrolyte project survey, the a-b conducting of T-valve 2, peristaltic pump 4 rotates, and sample is sucked ISE measurement module 3, carries out the measurement of electrolyte project, measures the peristaltic pump 4 that finishes and rotates, and sample is entered liquid waste treating apparatus 5.
2, biochemical and immune project survey, hyperchannel cross-over valve 7 turn to the reagent bottle inlet of a certain measurement project, the a-c conducting of T-valve 2, sampling valve 9 is in sample states, peristaltic pump 8 rotates, and reagent is pumped into reacting pipe 10, and sample is drawn onto sampling ring on the sampling valve 9; Sampling valve 9 is switched to the injection state, sample on the sampling ring switches to reagent passage, peristaltic pump 8 rotates, sample and reagent are together pumped into reacting pipe, on one side like this sample on one side and reagent reacting go ahead, pass through photoelectric detector 11 when being reacted to certain the time reaction product, the signal that is detected reaction product by photoelectric detector 11 changes, and then measure the content of project to be measured, and the final reaction product flows into liquid waste treating apparatus, and a project testing finishes.
The reagent bottle that turns to next project by hyperchannel cross-over valve 7 enters the mouth, and repeating step (2) is finished the measurement of another project, and such repetition like this can be carried out the measurement of a plurality of biochemistry and immune project.
It should be noted that at last: present embodiment only in order to the explanation the present invention and and unrestricted technical scheme described in the invention; Therefore, it will be understood by those of skill in the art that still and can make amendment or be equal to replacement the present invention although this instructions has been described in detail the present invention with reference to the foregoing description; And all do not break away from the technical scheme and the improvement thereof of the spirit and scope of the present invention, and it all should be encompassed in the claim scope of the present invention.

Claims (4)

1, a kind of blood analysis system that is used for the highly infective disease, comprise sample introduction mechanism, Measurement and analysis module, liquid waste treating apparatus and liquid-way system, it is characterized in that: described Measurement and analysis module is made up of electrolyte measurement module and biochemical measurement module, described electrolyte measurement module connects sample introduction mechanism and inserts liquid waste treating apparatus through peristaltic pump, described biochemical measurement module is connected to form successively by reagent container, reagent valve, peristaltic pump, sampling valve, reacting pipe and detecting device, described sampling valve connects sample introduction mechanism, and described detecting device connects liquid waste treating apparatus.
2, a kind of highly infective disease blood analysis system according to claim 1 is characterized in that: described sample introduction mechanism connects the sampling valve of electrolyte measurement module and biochemical measurement module by T-valve.
3, a kind of highly infective disease blood analysis system according to claim 1, it is characterized in that: described reagent valve is a hyperchannel cross-over valve.
4, according to the described arbitrary highly infective disease blood analysis system of claim 1 to 3, it is characterized in that: described liquid waste treating apparatus is an ozonization plant, and waste liquid is stored in the flexible containers.
CN2009101059124A 2009-03-02 2009-03-02 Blood analysis system used for high-communicable disease Expired - Fee Related CN101504419B (en)

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CN101504419B CN101504419B (en) 2012-02-08

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102095844A (en) * 2011-01-14 2011-06-15 张会生 Biochemical analyzer and biochemical analysis method thereof
CN114778629A (en) * 2022-04-28 2022-07-22 孟栋栋 Be used for clinical detection device that draws blood of medical treatment endocrinology branch of academic or vocational study

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2283853Y (en) * 1997-01-17 1998-06-10 镇江奥迪康医疗仪器有限责任公司 Electrolytic analytical instrument
CN2300911Y (en) * 1997-06-11 1998-12-16 深圳大学 Electrolyte analyzer for clinical diagnosis
JP4887113B2 (en) * 2006-10-25 2012-02-29 株式会社エイアンドティー Electrolyte analyzer

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102095844A (en) * 2011-01-14 2011-06-15 张会生 Biochemical analyzer and biochemical analysis method thereof
CN114778629A (en) * 2022-04-28 2022-07-22 孟栋栋 Be used for clinical detection device that draws blood of medical treatment endocrinology branch of academic or vocational study
CN114778629B (en) * 2022-04-28 2023-10-20 孟栋栋 Clinical blood drawing detection device for medical endocrinology department

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