CN101501207B - 合成基因组 - Google Patents

合成基因组 Download PDF

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Publication number
CN101501207B
CN101501207B CN200680052444.3A CN200680052444A CN101501207B CN 101501207 B CN101501207 B CN 101501207B CN 200680052444 A CN200680052444 A CN 200680052444A CN 101501207 B CN101501207 B CN 101501207B
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genome
synthetic
expression cassette
nucleic acid
genes
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Chinese (zh)
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CN101501207A (zh
Inventor
J·克雷格·文特尔
汉密尔顿·O·史密斯
克莱德·A·哈奇森三世
丹尼尔·G·吉布森
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Viridos Inc
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Synthetic Genomics Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN200680052444.3A 2005-12-06 2006-12-06 合成基因组 Active CN101501207B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74254205P 2005-12-06 2005-12-06
US60/742,542 2005-12-06
PCT/US2006/046803 WO2008024129A2 (en) 2005-12-06 2006-12-06 Synthetic genomes

Publications (2)

Publication Number Publication Date
CN101501207A CN101501207A (zh) 2009-08-05
CN101501207B true CN101501207B (zh) 2014-03-12

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US (2) US10041060B2 (https=)
EP (1) EP1968994B1 (https=)
JP (1) JP5106412B2 (https=)
CN (1) CN101501207B (https=)
AU (1) AU2006347573B2 (https=)
CA (1) CA2643356A1 (https=)
DK (1) DK1968994T3 (https=)
IL (1) IL192041A (https=)
WO (1) WO2008024129A2 (https=)

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US10093552B2 (en) 2008-02-22 2018-10-09 James Weifu Lee Photovoltaic panel-interfaced solar-greenhouse distillation systems
US9259662B2 (en) 2008-02-22 2016-02-16 James Weifu Lee Photovoltaic panel-interfaced solar-greenhouse distillation systems
US8986963B2 (en) * 2008-02-23 2015-03-24 James Weifu Lee Designer calvin-cycle-channeled production of butanol and related higher alcohols
DK2250276T3 (en) * 2008-02-23 2017-02-13 James Weifu Lee DESIGN ORGANISMS FOR PHOTOBIOLOGICAL PRODUCTION OF BUTANOL FROM CARBON DIOXIDE AND WATER
EP2285948B1 (en) 2008-03-03 2014-01-08 Joule Unlimited Technologies, Inc. Engineered co2 fixing microorganisms producing carbon-based products of interest
ES2560281T3 (es) 2008-10-17 2016-02-18 Joule Unlimited Technologies, Inc. Producción de etanol por microorganismos
EP3257942B1 (en) 2008-12-18 2020-07-22 ITI Scotland Limited Method for assembly of polynucleic acid sequences
SG10201400436PA (en) * 2009-03-06 2014-06-27 Synthetic Genomics Inc Methods For Cloning And Manipulating Genomes
US7794969B1 (en) 2009-07-09 2010-09-14 Joule Unlimited, Inc. Methods and compositions for the recombinant biosynthesis of n-alkanes
CA3056664A1 (en) 2009-09-25 2011-03-31 Alfred Gaertner Production of fatty acid derivatives in recombinant bacterial cells expressing an ester synthase variant
MX2012005069A (es) * 2009-10-30 2012-07-17 Synthetic Genomics Inc Codificar texto hacia secuencias de acido nucleico.
US20110269119A1 (en) 2009-10-30 2011-11-03 Synthetic Genomics, Inc. Encoding text into nucleic acid sequences
WO2011109031A1 (en) * 2010-03-05 2011-09-09 Synthetic Genomics, Inc. Methods for cloning and manipulating genomes
GB2481425A (en) 2010-06-23 2011-12-28 Iti Scotland Ltd Method and device for assembling polynucleic acid sequences
US20120135486A1 (en) 2010-09-14 2012-05-31 C/O Joule Unlimited Technologies, Inc. Methods and Compositions for the Extracellular Transport of Biosynthetic Hydrocarbons and Other Molecules
US8349587B2 (en) 2011-10-31 2013-01-08 Ginkgo Bioworks, Inc. Methods and systems for chemoautotrophic production of organic compounds
US8790901B2 (en) 2011-12-14 2014-07-29 Pronutria, Inc. Microorganisms and methods for producing unsaturated fatty acids
US9700071B2 (en) 2012-03-26 2017-07-11 Axcella Health Inc. Nutritive fragments, proteins and methods
EP2831098A4 (en) 2012-03-26 2016-12-07 Axcella Health Inc LOADED NUTRIENT PROTEINS AND METHODS
EP2831100A4 (en) 2012-03-26 2016-02-10 Pronutria Inc NUTRIENT PROTEINS AND METHOD
RU2634407C2 (ru) 2012-03-26 2017-10-26 Эксселла Хелт Инк. Фрагменты пищевых белков и способы их применения
GB201219989D0 (en) 2012-11-06 2012-12-19 Discuva Ltd Bacterial engineering
WO2014089436A1 (en) 2012-12-07 2014-06-12 Ginkgo Bioworks, Inc. Methods and systems for methylotrophic production of organic compounds
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
WO2015048339A2 (en) 2013-09-25 2015-04-02 Pronutria, Inc. Compositions and formulations for non-human nutrition and methods of production and use thereof
RU2016110800A (ru) 2013-09-25 2017-10-30 Пронутриа Биосайенсис, Инк. Составы и композиции для поддержания и увеличения мышечной массы, силы и результативности, и способы их производства и использования
WO2015054507A1 (en) 2013-10-10 2015-04-16 Pronutria, Inc. Nutritive polypeptide production systems, and methods of manufacture and use thereof
GB201413202D0 (en) 2014-07-25 2014-09-10 Discuva Ltd Process for producing bacterial mutants
US10538746B2 (en) 2016-03-17 2020-01-21 INVISTA North America S.à r.l. Polypeptides and variants having improved activity, materials and processes relating thereto
EP3433354B1 (en) 2016-03-23 2023-12-27 Synthetic Genomics, Inc. Generation of synthetic genomes
US11345938B2 (en) 2017-02-02 2022-05-31 Cargill, Incorporated Genetically modified cells that produce C6-C10 fatty acid derivatives
WO2019191761A1 (en) 2018-03-30 2019-10-03 Invista North America S.A.R.L. Method for controlling dissolved oxygen concentration in a continuous aerobic fermentation
CN111936623B (zh) 2018-03-30 2023-08-25 英威达纺织（英国）有限公司 用于生物合成制造庚二酸的材料与方法和合成多肽的利用
US12065636B2 (en) 2018-03-30 2024-08-20 Inv Nylon Chemicals Americas, Llc High hydrogen utilization and gas recycle
EP3775241A1 (en) 2018-03-30 2021-02-17 INVISTA Textiles (U.K.) Limited Methods for controlling oxygen concentration during aerobic biosynthesis
EP3788148A1 (en) 2018-05-02 2021-03-10 INVISTA Textiles (U.K.) Limited Materials and methods for maximizing biosynthesis through alteration of pyruvate-acetyl-coa-tca balance in species of the genera ralstonia and cupriavidus and organisms related thereto
WO2019213118A1 (en) 2018-05-02 2019-11-07 Invista North America S.A.R.L. Methods for controlling pha biosynthesis in cupriavidus or ralstonia
CN115807021A (zh) * 2022-08-01 2023-03-17 深圳大学 一种莱茵衣藻人工叶绿体基因组合成组装与功能测试的方法

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Also Published As

Publication number Publication date
EP1968994A4 (en) 2009-04-08
US20070264688A1 (en) 2007-11-15
IL192041A (en) 2013-08-29
DK1968994T3 (da) 2013-09-30
JP5106412B2 (ja) 2012-12-26
US10041060B2 (en) 2018-08-07
AU2006347573A1 (en) 2008-02-28
EP1968994A2 (en) 2008-09-17
WO2008024129A2 (en) 2008-02-28
CA2643356A1 (en) 2008-02-28
EP1968994B1 (en) 2013-07-03
CN101501207A (zh) 2009-08-05
IL192041A0 (en) 2008-12-29
JP2009518038A (ja) 2009-05-07
WO2008024129A3 (en) 2008-10-09
US20180340165A1 (en) 2018-11-29
AU2006347573B2 (en) 2013-01-17

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Free format text: FORMER OWNER: JOHN CRAIG VENTER RESEARCH CO., LTD.

Effective date: 20100512

CB03 Change of inventor or designer information

Inventor after: Smith Hamilton O.

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Inventor after: Hutchison Clyde A. III

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Free format text: CORRECT: INVENTOR; FROM: VENTER CRAIG J. SMITH HAMILTON O. TO: VENTER CRAIG J. SMITH HAMILTON O. HUTCHISON CLYDE A. III

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C53 Correction of patent of invention or patent application
CB03 Change of inventor or designer information

Inventor after: Smith Hamilton O.

Inventor after: Smith Hamilton O.

Inventor after: Hutchison Clyde A. III

Inventor after: Young Lei

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Free format text: CORRECT: INVENTOR; FROM: J. CRAIG VENTER HAMILTON O. SMITH CLYDE A. HUTCHISON III TO: J. CRAIG VENTER HAMILTON O. SMITH CLYDE A. HUTCHISON III DANIEL G. GIBSON

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