CN101466361B - 具有增加活性成分通量的含活性成分颗粒的透皮治疗系统 - Google Patents

具有增加活性成分通量的含活性成分颗粒的透皮治疗系统 Download PDF

Info

Publication number
CN101466361B
CN101466361B CN200780021134XA CN200780021134A CN101466361B CN 101466361 B CN101466361 B CN 101466361B CN 200780021134X A CN200780021134X A CN 200780021134XA CN 200780021134 A CN200780021134 A CN 200780021134A CN 101466361 B CN101466361 B CN 101466361B
Authority
CN
China
Prior art keywords
active ingredient
transdermal therapeutic
therapeutic system
inclusions
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200780021134XA
Other languages
English (en)
Chinese (zh)
Other versions
CN101466361A (zh
Inventor
M·霍斯特曼
M·扎梅蒂
T·容
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38520773&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101466361(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Publication of CN101466361A publication Critical patent/CN101466361A/zh
Application granted granted Critical
Publication of CN101466361B publication Critical patent/CN101466361B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200780021134XA 2006-06-08 2007-05-30 具有增加活性成分通量的含活性成分颗粒的透皮治疗系统 Expired - Fee Related CN101466361B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102006026578A DE102006026578B4 (de) 2006-06-08 2006-06-08 Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung
DE102006026578.5 2006-06-08
PCT/EP2007/004765 WO2007140909A1 (de) 2006-06-08 2007-05-30 Wirkstoffpartikelhaltiges transdermales therapeutisches system mit erhöhtem wirkstofffluss

Publications (2)

Publication Number Publication Date
CN101466361A CN101466361A (zh) 2009-06-24
CN101466361B true CN101466361B (zh) 2012-01-04

Family

ID=38520773

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200780021134XA Expired - Fee Related CN101466361B (zh) 2006-06-08 2007-05-30 具有增加活性成分通量的含活性成分颗粒的透皮治疗系统

Country Status (13)

Country Link
US (2) US10292942B2 (enExample)
EP (1) EP2029121B1 (enExample)
JP (1) JP5757682B2 (enExample)
CN (1) CN101466361B (enExample)
AT (1) ATE459345T1 (enExample)
BR (1) BRPI0712420A2 (enExample)
CA (1) CA2652216C (enExample)
DE (2) DE102006026578B4 (enExample)
DK (1) DK2029121T3 (enExample)
ES (1) ES2340732T3 (enExample)
PL (1) PL2029121T3 (enExample)
PT (1) PT2029121E (enExample)
WO (1) WO2007140909A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006026578B4 (de) * 2006-06-08 2009-01-08 Lts Lohmann Therapie-Systeme Ag Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung
US8369942B2 (en) * 2008-03-20 2013-02-05 The Invention Science Fund I, Llc Subdermal material delivery device
JP5552255B2 (ja) 2008-04-16 2014-07-16 日東電工株式会社 薬物経皮投与デバイス
US20110033545A1 (en) * 2009-08-06 2011-02-10 Absize, Inc. Topical pharmaceutical preparations having both a nanoparticle solution and a nanoparticle suspension and methods for the treatment of acute and chronic pain therewith
DE102011100619A1 (de) 2010-05-05 2012-01-05 Amw Gmbh Transdermales therapeutisches System (TTS) mit einem Gehalt an einem Opiod-Analgetikum
EA201300255A1 (ru) 2010-08-23 2013-06-28 Такеда Гмбх Увлажненные частицы, содержащие терапевтически активное вещество
DE102011090178A1 (de) * 2011-12-30 2013-07-04 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit geringer Neigung zur Spontankristallisation
AU2014276910B2 (en) 2013-06-04 2017-03-09 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system
EP3209389B1 (en) 2014-10-21 2019-10-02 The Procter and Gamble Company Kit for improving skin appearance
CN104758181A (zh) * 2015-04-09 2015-07-08 史祎 一种无溶剂贴敷剂制备工艺
CN108135786B (zh) 2015-10-22 2022-05-17 宝洁公司 发泡膜的阻隔贴片和改善皮肤外观的方法
US10576023B2 (en) 2015-10-22 2020-03-03 The Procter & Gamble Company Barrier patch of a foamed film and methods of improving skin appearance
US10751265B2 (en) * 2017-01-09 2020-08-25 The Procter & Gamble Barrier patch with soluble film and methods of improving skin appearance
US10806681B2 (en) 2017-01-09 2020-10-20 The Procter & Gamble Company Barrier patch with soluble film and methods of improving skin appearance
US10857076B2 (en) 2017-01-09 2020-12-08 The Procter & Gamble Company Barrier patch with soluble film and methods of improving skin appearance
CN110769945B (zh) * 2017-06-22 2023-01-24 宝洁公司 包括水溶性层和气相沉积涂层的美容护理品膜
KR102524880B1 (ko) * 2017-12-21 2023-04-21 한양대학교 산학협력단 하이드로콜로이드 조성물 및 이를 포함하는 바이오 패치
WO2019183010A1 (en) 2018-03-19 2019-09-26 The Procter & Gamble Company Method of making a barrier patch with soluble film
US12491166B2 (en) 2020-08-31 2025-12-09 Wacker Chemie Ag Method of delivering an active compound and delivery device for use in the same
US12201733B2 (en) * 2021-03-08 2025-01-21 Nikita Patel Transdermal delivery system

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0391172A1 (de) * 1989-04-01 1990-10-10 LTS Lohmann Therapie-Systeme GmbH & Co. KG Transdermales therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung
EP0481443A1 (en) * 1990-10-17 1992-04-22 Vectorpharma International S.P.A. Transdermal therapeutic compositions
WO2000047191A1 (de) * 1999-02-10 2000-08-17 Jenapharm Gmbh & Co. Kg Wirkstoffhaltige laminate für transdermalsysteme

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3965482A (en) * 1974-11-12 1976-06-22 Rca Corporation Velocity correction circuit for video discs
US4460372A (en) 1981-02-17 1984-07-17 Alza Corporation Percutaneous absorption enhancer dispenser for use in coadministering drug and percutaneous absorption enhancer
US4687481A (en) 1984-10-01 1987-08-18 Biotek, Inc. Transdermal drug delivery system
DE3587616D1 (de) * 1984-12-22 1993-11-11 Sanol Arznei Schwarz Gmbh Wirkstoffpflaster.
GB8629640D0 (en) 1986-12-11 1987-01-21 Beecham Group Plc Composition & method
US5059189A (en) 1987-09-08 1991-10-22 E. R. Squibb & Sons, Inc. Method of preparing adhesive dressings containing a pharmaceutically active ingredient
IT1230566B (it) 1988-10-17 1991-10-28 Vectorpharma Int Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione
US5270358A (en) * 1989-12-28 1993-12-14 Minnesota Mining And Manufacturing Company Composite of a disperesed gel in an adhesive matrix
DE4332093C2 (de) * 1993-09-22 1995-07-13 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit dem Wirkstoff Acetylsalicylsäure und Verfahren zu seiner Herstellung
JPH0912448A (ja) * 1995-04-28 1997-01-14 Read Chem Kk 薬物放出制御型経皮吸収製剤
US6238700B1 (en) 1995-12-01 2001-05-29 Alza Corporation Method for preventing crystal formation in a dispersion of a liquid in a matrix
DE19652196A1 (de) 1996-12-16 1998-06-18 Jenapharm Gmbh Homogene steroidhaltige Präformulierungen zur Herstellung niedrigdosierter fester und halbfester pharmazeutischer Zubereitungen
WO1999017868A1 (de) * 1997-10-06 1999-04-15 Adalbert-Raps-Stiftung Verfahren zur herstellung eines pulverförmigen produktes aus einem flüssigen stoff oder stoffgemisch
DE19844079A1 (de) * 1998-05-22 1999-11-25 Novosis Pharma Ag Biphasische Transdermalsysteme
FI20010115A0 (fi) * 2001-01-18 2001-01-18 Orion Corp Menetelmä nanopartikkelien valmistamiseksi
DE10136784A1 (de) * 2001-07-27 2003-02-20 Lohmann Therapie Syst Lts Darreichungsformen mit wirkstoffhaltigen Partikeln, zur Anwendung auf der Haut oder Schleimhaut
DE10234673B4 (de) 2002-07-30 2007-08-16 Schwarz Pharma Ag Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
DE102006026578B4 (de) * 2006-06-08 2009-01-08 Lts Lohmann Therapie-Systeme Ag Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0391172A1 (de) * 1989-04-01 1990-10-10 LTS Lohmann Therapie-Systeme GmbH & Co. KG Transdermales therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung
EP0481443A1 (en) * 1990-10-17 1992-04-22 Vectorpharma International S.P.A. Transdermal therapeutic compositions
WO2000047191A1 (de) * 1999-02-10 2000-08-17 Jenapharm Gmbh & Co. Kg Wirkstoffhaltige laminate für transdermalsysteme

Also Published As

Publication number Publication date
WO2007140909A1 (de) 2007-12-13
ATE459345T1 (de) 2010-03-15
US10596126B2 (en) 2020-03-24
CA2652216C (en) 2016-02-16
JP2009539786A (ja) 2009-11-19
DE102006026578B4 (de) 2009-01-08
EP2029121B1 (de) 2010-03-03
DE102006026578A1 (de) 2007-12-13
DK2029121T3 (da) 2010-06-07
PT2029121E (pt) 2010-05-11
US20090258062A1 (en) 2009-10-15
BRPI0712420A2 (pt) 2012-09-04
PL2029121T3 (pl) 2010-06-30
ES2340732T3 (es) 2010-06-08
CN101466361A (zh) 2009-06-24
DE502007003020D1 (de) 2010-04-15
US10292942B2 (en) 2019-05-21
CA2652216A1 (en) 2007-12-13
EP2029121A1 (de) 2009-03-04
JP5757682B2 (ja) 2015-07-29
US20190231710A1 (en) 2019-08-01

Similar Documents

Publication Publication Date Title
CN101466361B (zh) 具有增加活性成分通量的含活性成分颗粒的透皮治疗系统
ES2285234T3 (es) Dispositivo para la administracion transdermica de una base de rotigotina.
JP2552191B2 (ja) 高い活性物質流を示す皮膚経由医療デバイス及びその製造方法
JP6060213B2 (ja) 外用医薬組成物を用いた貼付剤
EP1225951A2 (en) A dual adhesive transdermal drug delivery system
JP2017505312A (ja) 乱用および誤用抑止経皮システム
JP2015503541A (ja) 自発的に結晶化する傾向が低い経皮治療システム
WO2004110445A1 (ja) フェンタニル含有口腔粘膜貼付剤
JP2003515555A (ja) 同一有効成分を含有する貯留部と基質部を備えた経皮投与部材
US7763274B2 (en) Administration form with active substance-containing particles, for application on the skin or mucosa
JP3834202B2 (ja) 活性物質スコポラミン塩基を含有する経皮的治療システム
CN112107561B (zh) 含有壳聚糖的药物制剂、药物透皮贴剂及其制备方法
JPH02149514A (ja) 医薬部材
JP3497309B2 (ja) 貼付剤
US20040241231A1 (en) Flat, oral dosage form comprising particles containing active ingredients
KR20010053314A (ko) 진주 안료를 첨가한 의약 방출 시스템
KR20110012727A (ko) 니코틴 경피 전달 패취
JPH01131115A (ja) クレボプリド経皮貼付剤
MXPA99006051A (en) Extremely flexible plaster acting dermally or transdermally, and method for producing same

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120104