CN101461839A - Composition with function for promoting lead-expelling and method for preparing the same - Google Patents

Composition with function for promoting lead-expelling and method for preparing the same Download PDF

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Publication number
CN101461839A
CN101461839A CNA2007101799562A CN200710179956A CN101461839A CN 101461839 A CN101461839 A CN 101461839A CN A2007101799562 A CNA2007101799562 A CN A2007101799562A CN 200710179956 A CN200710179956 A CN 200710179956A CN 101461839 A CN101461839 A CN 101461839A
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China
Prior art keywords
extract
lead
preparation
weight portion
expelling function
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007101799562A
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Chinese (zh)
Inventor
孙岱
张卫华
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Beijing Increase Pharmaceutical Technology Co Ltd
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Beijing Increase Pharmaceutical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Beijing Increase Pharmaceutical Technology Co Ltd filed Critical Beijing Increase Pharmaceutical Technology Co Ltd
Priority to CNA2007101799562A priority Critical patent/CN101461839A/en
Publication of CN101461839A publication Critical patent/CN101461839A/en
Pending legal-status Critical Current

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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a composition with function of promoting lead-discharging and a preparation method thereof. The composition can be prepared into preparation formulations including tablet, capsule, granular and oral liquid by taking a mung bean extract, a Hangzhou white chrysanthemum extract, a liquorice extract and chitosan oligosaccharide as raw materials and adding pharmaceutically acceptable auxiliary materials according to proper proportion.

Description

A kind of composition and method of making the same with promotion lead-expelling function
Technical field
The present invention relates to a kind of composition and method of making the same that promotes lead-expelling function that has.
Background technology
Along with development of modern industry, lead contamination and harm are more and more paid attention to by people.Construction material, the anti-auxilliary industries such as material, font printing and accumulator of penetrating all can be brought pollution producing, use, discarding in the process.Particularly lead-containing materials reclaims as effective environmental protection, will cause environment to be difficult for the destruction of improving, and people's digestion, nerve, circulation, hemopoietic system etc. are worked the mischief.The child is to plumbous exposure height sensitivity, and plumbous main influence to the child is the infringement to nervous system, hemopoietic system and kidney, and in addition, plumbous also have certain toxic action to digestion, immunity and upgrowth and development of children.
Summary of the invention
The object of the invention is to provide a kind of compositions that promotes lead-expelling function that has.
Another purpose of the present invention is to provide a kind of lead-expelling function of promotion preparation of compositions method that has.
The present invention is implemented by the following technical programs.
The present composition can be made by the raw material of following weight portion:
Semen phaseoli radiati extract 1-4 Flos Chrysanthemi extract 1-8
Radix Glycyrrhizae extract 1.5-9 oligochitosan 2.5-10.
The present composition can add suitable pharmaceutical necessities and make a kind of dosage form in tablet, oral solutions, capsule, the granule.Pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, hydroxypropyl cellulose, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, Polyethylene Glycol, potassium sorbate, Aspartane, ethyl hydroxybenzoate, propyl hydroxybenzoate wherein one or more.
The present invention has the lead-expelling function of promotion preparation of compositions method, can take following steps: get Semen phaseoli radiati extract, Flos Chrysanthemi extract, Radix Glycyrrhizae extract, oligochitosan in proportion, adding purified water 12-400 weight portion is standby, stir, embedding, sterilization promptly gets oral solutions.
Also can add antiseptic 0.01-0.8 weight portion, correctives 0.06-4 weight portion in the above-mentioned oral solutions.
Semen phaseoli radiati extract, Flos Chrysanthemi extract, Radix Glycyrrhizae extract are and adopt routine techniques to make from Semen phaseoli radiati, Flos Chrysanthemi, Radix Glycyrrhizae respectively among the present invention.
Oligochitosan also claims chitin oligosaccharide, and formal name used at school is β-1, and 4-oligomerization-glucamine is to be raw material with the chitosan, the high low molecular weight product of good water solubility, biological activity that forms through biotechnology degraded.Oligochitosan is at human body internal absorption factor height.Studies have shown that: oligochitosan has the immunity of raising, suppress the growth of cancerous protuberance cell, promote liver spleen antibody to form, promote the absorption of calcium and mineral, human body beneficial's floras such as propagation bacillus bifidus, lactobacillus, blood fat reducing, blood pressure lowering, blood sugar lowering, cholesterol regulating, fat-reducing, functions such as prevention adult disease can be applicable to fields such as medicine, functional food.Oligochitosan can obviously be eliminated human body negative oxygen ion free radical, activation equipment somatic cell, slow down aging.
Semen phaseoli radiati is the function that refreshing and detoxicating is arranged, and contains materials such as Semen phaseoli radiati albumen, polypeptide, tannic acid, flavone compound in the Semen phaseoli radiati extract that adopts conventional method to make, and these materials all might be with plumbous in conjunction with forming precipitate and excreting.
Radix Glycyrrhizae, Flos Chrysanthemi are natural Chinese medicinal herb, are rich in trace element and plumbous are absorbed with antagonism in small intestinal, can reduce plumbous absorption.Flos Chrysanthemi is rich in vitamin C, can excrete in conjunction with forming precipitation with plumbous.
The raw material of using in the present composition all is taken from natural, when having the Plumbum removing effect, but balance coordination human physiological functions also avoided using the loss that the Western medicine chelating agent causes trace element in the body, human body is not had detrimental effect.The above-mentioned raw materials compatibility uses, the energy Synergistic, and can not make the body trace element loss.
The functional test result of the present composition shows to have the Plumbum removing of promotion effect.
The specific embodiment
The present invention is described further by embodiment.
Embodiment 1
Get Semen phaseoli radiati extract 1Kg, Flos Chrysanthemi extract 1Kg, Radix Glycyrrhizae extract 1.5Kg, oligochitosan 2.5Kg, add purified water 12Kg, be stirred to dissolving fully, embedding, sterilization promptly gets oral solutions.
Embodiment 2
Get Semen phaseoli radiati extract 4Kg, Flos Chrysanthemi extract 8Kg, Radix Glycyrrhizae extract 9Kg, oligochitosan 10Kg, add purified water 400Kg, be stirred to dissolving fully, embedding, sterilization promptly gets oral solutions.
Embodiment 3
Get Semen phaseoli radiati extract 2Kg, Flos Chrysanthemi extract 4Kg, Radix Glycyrrhizae extract 5Kg, oligochitosan 6Kg, add purified water 200Kg, be stirred to dissolving fully, embedding, sterilization promptly gets oral solutions.
Embodiment 4
Get Semen phaseoli radiati extract 3Kg, Flos Chrysanthemi extract 2Kg, Radix Glycyrrhizae extract 4Kg, oligochitosan 8Kg, potassium sorbate 0.03Kg, Aspartane 0.1Kg, add purified water 100Kg, be stirred to dissolving fully, embedding, sterilization promptly gets oral solutions.
Embodiment 5
Get Semen phaseoli radiati extract 3Kg, Flos Chrysanthemi extract 4Kg, Radix Glycyrrhizae extract 8Kg, oligochitosan 6Kg, mannitol 18Kg, evenly mixed, make tablet according to a conventional method, promptly.
Embodiment 6
Get Semen phaseoli radiati extract 2Kg, Flos Chrysanthemi extract 6Kg, Radix Glycyrrhizae extract 2Kg, oligochitosan 5Kg, lactose 15Kg, evenly mixed, make granule according to a conventional method, promptly.
Embodiment 7
Get Semen phaseoli radiati extract 4Kg, Flos Chrysanthemi extract 3Kg, Radix Glycyrrhizae extract 7Kg, oligochitosan 9Kg, starch 25Kg, evenly mixed, make tablet according to a conventional method, promptly.
Embodiment 8
Get Semen phaseoli radiati extract 3Kg, Flos Chrysanthemi extract 2Kg, Radix Glycyrrhizae extract 6Kg, oligochitosan 7Kg, microcrystalline Cellulose 22Kg, evenly mixed, make capsule according to a conventional method, promptly.
Embodiment 9
Get Semen phaseoli radiati extract 3.4Kg, Flos Chrysanthemi extract 3.5Kg, Radix Glycyrrhizae extract 7.1Kg, oligochitosan 8.3Kg, starch 15Kg, evenly mixed, make capsule according to a conventional method, promptly.

Claims (5)

1, a kind of compositions with promotion lead-expelling function is characterized in that being made by the raw material of following weight portion:
Semen phaseoli radiati extract 1-4 Flos Chrysanthemi extract 1-8
Radix Glycyrrhizae extract 1.5-9 oligochitosan 2.5-10.
2, the preparation of compositions method that has lead-expelling function according to claim 1 is characterized in that adding suitable pharmaceutical necessities and makes a kind of dosage form in tablet, capsule, oral solutions, the granule.
3, as having the preparation of compositions method of lead-expelling function as described in the claim 2, it is characterized in that pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, hydroxypropyl cellulose, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, Polyethylene Glycol, potassium sorbate, Aspartane, ethyl hydroxybenzoate, propyl hydroxybenzoate wherein one or more.
4, have lead-expelling function preparation of compositions method according to claim 1, it is characterized in that comprising the steps:
Get Semen phaseoli radiati extract, Flos Chrysanthemi extract, Radix Glycyrrhizae extract, oligochitosan in proportion, adding purified water 12-400 weight portion is standby, stir, and embedding, sterilization promptly gets oral solutions.
5, as having the preparation of compositions method of lead-expelling function as described in the claim 4, it is characterized in that also can adding antiseptic 0.01-0.8 weight portion, correctives 0.06-4 weight portion.
CNA2007101799562A 2007-12-20 2007-12-20 Composition with function for promoting lead-expelling and method for preparing the same Pending CN101461839A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNA2007101799562A CN101461839A (en) 2007-12-20 2007-12-20 Composition with function for promoting lead-expelling and method for preparing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNA2007101799562A CN101461839A (en) 2007-12-20 2007-12-20 Composition with function for promoting lead-expelling and method for preparing the same

Publications (1)

Publication Number Publication Date
CN101461839A true CN101461839A (en) 2009-06-24

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102726721A (en) * 2011-12-21 2012-10-17 聂存良 Balanced trace element lead-removing oral liquid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102726721A (en) * 2011-12-21 2012-10-17 聂存良 Balanced trace element lead-removing oral liquid

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Open date: 20090624