CN101461823A - Composition with function for promoting lead-expelling and method for preparing the same - Google Patents
Composition with function for promoting lead-expelling and method for preparing the same Download PDFInfo
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- CN101461823A CN101461823A CNA2007101799577A CN200710179957A CN101461823A CN 101461823 A CN101461823 A CN 101461823A CN A2007101799577 A CNA2007101799577 A CN A2007101799577A CN 200710179957 A CN200710179957 A CN 200710179957A CN 101461823 A CN101461823 A CN 101461823A
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Abstract
The invention discloses a composition with the function of promoting lead-discharging and a preparation method thereof. The composition can be prepared into preparation formulations including tablet, capsule, granule and oral liquid by taking stachyose, algal polysaccharide, chitosan oligosaccharide, zinc gluconate and calcium gluconate as raw materials and adding pharmaceutically acceptable auxiliary materials according to proper proportion.
Description
Technical field
The present invention relates to a kind of composition and method of making the same that promotes lead-expelling function that has.
Background technology
Along with development of modern industry, lead contamination and harm are more and more paid attention to by people.Construction material, the anti-auxilliary industries such as material, font printing and accumulator of penetrating all can be brought pollution producing, use, discarding in the process.Particularly lead-containing materials reclaims as effective environmental protection, will cause environment to be difficult for the destruction of improving, and people's digestion, nerve, circulation, hemopoietic system etc. are worked the mischief.The child is to plumbous exposure height sensitivity, and plumbous main influence to the child is the infringement to nervous system, hemopoietic system and kidney, and in addition, plumbous also have certain toxic action to digestion, immunity and upgrowth and development of children.
Summary of the invention
The object of the invention is to provide a kind of compositions that promotes lead-expelling function that has.
Another purpose of the present invention is to provide a kind of lead-expelling function of promotion preparation of compositions method that has.
The present invention is implemented by the following technical programs.
The present composition can be made by the raw material of following weight portion:
Stachyose 5-10 Sargassum polysaccharides 1-10 oligochitosan 3-9
Calcium gluconate 20-60 zinc gluconate 1-3.
The present composition can add suitable pharmaceutical necessities and make a kind of dosage form in tablet, oral solutions, capsule, the granule.Pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, hydroxypropyl cellulose, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, Polyethylene Glycol, potassium sorbate, Aspartane, ethyl hydroxybenzoate, propyl hydroxybenzoate wherein one or more.
The present invention has the lead-expelling function of promotion preparation of compositions method, can take following steps: the threose of fetching water in proportion, Sargassum polysaccharides, oligochitosan, zinc gluconate, calcium gluconate, and adding purified water 60-1000 weight portion is standby, stir, embedding, sterilization promptly gets oral solutions.
Also can add antiseptic 0.03-1.2 weight portion, correctives 0.12-6 weight portion in the above-mentioned oral solutions.
Stachyose (stachyose) is a kind of functional oligose of gala saccharide, belongs to cottonseed sugar and belongs to nonreducing sugar.Stachyose can produce L one lactic acid after being decomposed by bacillus bifidus on the one hand, and L one lactic acid in the caecum can increase its dissolubility in conjunction with calcium, causes the calcium absorption ability to strengthen.On the other hand, stachyose can promote synthetic vitamin B group, thereby significantly reduces the absorption of intestinal to lead.Stachyose is accelerated body metabolism by improving the intestinal microecology system, and the lead that enters in the intestinal is played good anti-Absorption, can reduce the probability that enters blood and tissue, slows down the murder by poisoning to human body.
Oligochitosan also claims chitin oligosaccharide, and formal name used at school is β-1, and 4-oligomerization-glucamine is to be raw material with the chitosan, the high low molecular weight product of good water solubility, biological activity that forms through biotechnology degraded.Oligochitosan is at human body internal absorption factor height.Studies have shown that: oligochitosan has the immunity of raising, suppress the growth of cancerous protuberance cell, promote liver spleen antibody to form, promote the absorption of calcium and mineral, human body beneficial's floras such as propagation bacillus bifidus, lactobacillus, blood fat reducing, blood pressure lowering, blood sugar lowering, cholesterol regulating, fat-reducing, functions such as prevention adult disease can be applicable to fields such as medicine, functional food.Oligochitosan can obviously be eliminated human body negative oxygen ion free radical, activation equipment somatic cell, slow down aging.
Sargassum polysaccharides has effects such as enhancing immunity, antioxidation for to extract from marine microalgae, simultaneously since high molecular polymer characteristic and alga cells wall surface long-pending big, stickiness is big, with certain negative charge, be easy to the enriched lead ion, excrete.
Calcium gluconate, zinc gluconate institute calcic, zinc element in small intestinal can and the plumbous antagonism mechanism that absorbs that forms, reduce plumbous absorption.
The material combination used in the present composition is used, and when having the Plumbum removing of promotion effect, but antioxidation also improves body immunity, has avoided using the loss that the Western medicine chelating agent causes trace element in the body.
The above-mentioned raw materials compatibility uses, can Synergistic.
The functional test result of the present composition shows to have the Plumbum removing of promotion effect.
The specific embodiment
The present invention is described further by embodiment.
Embodiment 1
Water intaking threose 5Kg, Sargassum polysaccharides 1Kg, oligochitosan 3Kg, calcium gluconate 20Kg, zinc gluconate 1Kg add purified water 60Kg, are stirred to dissolving fully, embedding, and sterilization promptly gets oral solutions.
Embodiment 2
Water intaking threose 10Kg, Sargassum polysaccharides 10Kg, oligochitosan 9Kg, calcium gluconate 60Kg, zinc gluconate 3Kg add purified water 1000Kg, are stirred to dissolving fully, embedding, and sterilization promptly gets oral solutions.
Embodiment 3
Water intaking threose 7Kg, Sargassum polysaccharides 6Kg, oligochitosan 5Kg, calcium gluconate 34Kg, zinc gluconate 2Kg add purified water 514Kg, are stirred to dissolving fully, embedding, and sterilization promptly gets oral solutions.
Embodiment 4
Water intaking threose 5Kg, Sargassum polysaccharides 9Kg, oligochitosan 4Kg, calcium gluconate 31Kg, zinc gluconate 2.2Kg, potassium sorbate 0.2Kg add purified water 120Kg, are stirred to dissolving fully, embedding, and sterilization promptly gets oral solutions.
Embodiment 5
Water intaking threose 6Kg, Sargassum polysaccharides 4Kg, oligochitosan 5.8Kg, calcium gluconate 23Kg, zinc gluconate 2.5Kg, mannitol 35Kg, evenly mixed, make tablet according to a conventional method, promptly.
Embodiment 6
Water intaking threose 8Kg, Sargassum polysaccharides 9Kg, oligochitosan 4Kg, calcium gluconate 50Kg, zinc gluconate 1.5Kg, lactose 80Kg, evenly mixed, make granule according to a conventional method, promptly.
Embodiment 7
Water intaking threose 7Kg, Sargassum polysaccharides 4Kg, oligochitosan 6Kg, calcium gluconate 55Kg, zinc gluconate 2Kg, dextrin 99Kg, evenly mixed, make granule according to a conventional method, promptly.
Embodiment 8
Water intaking threose 5Kg, Sargassum polysaccharides 6Kg, oligochitosan 8Kg, calcium gluconate 23Kg, zinc gluconate 3Kg, starch 60Kg, evenly mixed, make tablet according to a conventional method, promptly.
Embodiment 9
Water intaking threose 7.3Kg, Sargassum polysaccharides 8.4Kg, oligochitosan 4Kg, calcium gluconate 39Kg, zinc gluconate 1.8Kg, starch 30Kg, hydroxypropyl cellulose 20Kg, evenly mixed, make tablet according to a conventional method, promptly.
Claims (5)
1, a kind of compositions with promotion lead-expelling function is characterized in that being made by the raw material of following weight portion:
Stachyose 5-10 Sargassum polysaccharides 1-10 oligochitosan 3-9
Calcium gluconate 20-60 zinc gluconate 1-3.
2, the preparation of compositions method that has lead-expelling function according to claim 1 is characterized in that adding suitable pharmaceutical necessities and makes a kind of dosage form in tablet, capsule, oral solutions, the granule.
3, as having the preparation of compositions method of lead-expelling function as described in the claim 2, it is characterized in that pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, hydroxypropyl cellulose, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, Polyethylene Glycol, potassium sorbate, Aspartane, ethyl hydroxybenzoate, propyl hydroxybenzoate wherein one or more.
4, have lead-expelling function preparation of compositions method according to claim 1, it is characterized in that comprising the steps:
Fetch water in proportion threose, Sargassum polysaccharides, oligochitosan, zinc gluconate, calcium gluconate, it is standby to add purified water 60-1000 weight portion, stir, embedding, sterilization promptly gets oral solutions.
5, as having the preparation of compositions method of lead-expelling function as described in the claim 4, it is characterized in that also can adding antiseptic 0.03-1.2 weight portion, correctives 0.12-6 weight portion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101799577A CN101461823A (en) | 2007-12-20 | 2007-12-20 | Composition with function for promoting lead-expelling and method for preparing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101799577A CN101461823A (en) | 2007-12-20 | 2007-12-20 | Composition with function for promoting lead-expelling and method for preparing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101461823A true CN101461823A (en) | 2009-06-24 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101799577A Pending CN101461823A (en) | 2007-12-20 | 2007-12-20 | Composition with function for promoting lead-expelling and method for preparing the same |
Country Status (1)
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| CN (1) | CN101461823A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103875667A (en) * | 2012-12-21 | 2014-06-25 | 中国科学院大连化学物理研究所 | Antioxidant and application thereof |
| CN107006863A (en) * | 2017-04-13 | 2017-08-04 | 广东太阳神集团有限公司 | It is a kind of to promote health food of lead discharging and preparation method thereof |
| CN107432476A (en) * | 2017-07-05 | 2017-12-05 | 阎艺方 | A kind of nutraceutical for promoting lead discharging |
| CN110840828A (en) * | 2018-08-20 | 2020-02-28 | 浙江长典医药有限公司 | Preparation method of zinc gluconate oral liquid |
-
2007
- 2007-12-20 CN CNA2007101799577A patent/CN101461823A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103875667A (en) * | 2012-12-21 | 2014-06-25 | 中国科学院大连化学物理研究所 | Antioxidant and application thereof |
| CN103875667B (en) * | 2012-12-21 | 2016-06-15 | 中国科学院大连化学物理研究所 | A kind of antioxidant and application thereof |
| CN107006863A (en) * | 2017-04-13 | 2017-08-04 | 广东太阳神集团有限公司 | It is a kind of to promote health food of lead discharging and preparation method thereof |
| CN107432476A (en) * | 2017-07-05 | 2017-12-05 | 阎艺方 | A kind of nutraceutical for promoting lead discharging |
| CN110840828A (en) * | 2018-08-20 | 2020-02-28 | 浙江长典医药有限公司 | Preparation method of zinc gluconate oral liquid |
| CN110840828B (en) * | 2018-08-20 | 2021-12-21 | 浙江长典药物技术开发有限公司 | Preparation method of zinc gluconate oral liquid |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090624 |