CN101461855A - Composition with function for promoting lead-expelling and method for preparing the same - Google Patents
Composition with function for promoting lead-expelling and method for preparing the same Download PDFInfo
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- CN101461855A CN101461855A CNA2007101799613A CN200710179961A CN101461855A CN 101461855 A CN101461855 A CN 101461855A CN A2007101799613 A CNA2007101799613 A CN A2007101799613A CN 200710179961 A CN200710179961 A CN 200710179961A CN 101461855 A CN101461855 A CN 101461855A
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- vitamin
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- taurine
- expelling function
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Abstract
The invention discloses a composition with function of promoting lead-discharging and a preparation method thereof. The composition can be prepared into preparation formulations including tablet, capsule, granule and oral liquid by taking a dark plum extract, taurine, zinc gluconate, vitamin C and vitamin B1 as raw materials and adding pharmaceutically acceptable auxiliary materials according to proper proportion.
Description
Technical field
The present invention relates to a kind of composition and method of making the same that promotes lead-expelling function that has.
Background technology
Along with development of modern industry, lead contamination and harm are more and more paid attention to by people.Construction material, the anti-auxilliary industries such as material, font printing and accumulator of penetrating all can be brought pollution producing, use, discarding in the process.Particularly lead-containing materials reclaims as effective environmental protection, will cause environment to be difficult for the destruction of improving, and people's digestion, nerve, circulation, hemopoietic system etc. are worked the mischief.The child is to plumbous exposure height sensitivity, and plumbous main influence to the child is the infringement to nervous system, hemopoietic system and kidney, and in addition, plumbous also have certain toxic action to digestion, immunity and upgrowth and development of children.
Summary of the invention
The wood goal of the invention is to provide a kind of compositions that promotes lead-expelling function that has.
Another purpose of the present invention is to provide a kind of lead-expelling function of promotion preparation of compositions method that has.
The present invention is implemented by the following technical programs.
The present composition can be made by the raw material of following weight portion:
Fructus Mume extract 400-1400 taurine 100-500 zinc gluconate 100-300
Vitamin B
15-20 vitamin C 40-300.
The present composition can add suitable pharmaceutical necessities and make a kind of dosage form in tablet, oral solutions, capsule, the granule.Pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, hydroxypropyl cellulose, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, Polyethylene Glycol, potassium sorbate, Aspartane, ethyl hydroxybenzoate, propyl hydroxybenzoate, cane sugar powder, micropowder silica gel, citric acid, Pulvis Talci, magnesium stearate, stevioside, milk-taste essence, xanthan gum, carrageenan wherein one or more.
The present invention has the lead-expelling function of promotion preparation of compositions method, can take following steps: get Fructus Mume extract, taurine, zinc gluconate, vitamin C, vitamin B in proportion
1, add filler, correctives is standby, make tablet according to a conventional method and get final product.
Filler can be selected from one or more in xylitol, mannitol, the lactose in the invention described above tablet; Correctives can be selected from one or more of Aspartane, stevioside, milk-taste essence, citric acid, and concrete consumption is determined to get final product according to conventional amount used.
Fructus Mume is traditional natural drug, is rich in compositions such as organic acid.Fructus Mume extract system adopts decocting or water decoction-alcohol sedimentation to wait until that common process extracts from Fructus Mume, compositions such as the organic acid that is rich in can with plumbous combination in the body, form precipitation and excrete.
Taurine has facilitation to absorption and the transhipment of Zn, can obviously increase Zn in the absorption of enteral and each mainly organizes the content of internal organs in vivo.Taurine can also antioxidation, slow down aging, enhancing body DNA repair ability, and the indirect adjustments and controls genetic transcription.In addition, taurine also can strengthen the absorption of fatsoluble vitamin.Taurine has the oxygen-derived free radicals of removing, anti peroxidation of lipid thing damage effect and taurine dosage and is dependency relationships.
Vitamin C can form a kind of Ascorbate that dissociates that is difficult for lead, and this kind material can excrete from intestinal with feces, makes lead be difficult for precipitating in brain, histoorgan.In addition, vitamin C also is a kind of important antioxidants in the body.Because reversibly hydrogenation or dehydrogenation of vitamin C is so play an important role in the many in vivo redox reaction of vitamin C.For example, the active group of many enzymes be sulfydryl (-SH), vitamin C can keep-SH is in reducing condition and keeps the activity of enzyme; Vitamin C can make oxidized form of glutathione change reduced glutathion (GSH) into, the hydrogen-peroxide reduction that organism metabolism is produced; Vitamin C also can protect vitamin A, E and some vitamin B group to avoid oxidation.
Discover, give vitamin C and B simultaneously
1All can effectively reduce Pb-B, and make lead tolerance reduction in liver, the kidney and other organs, the pharmacology work share with both and is maximum.
Zinc gluconate can be in small intestinal the absorption of antagonism lead, the Plumbum absorption amount is reduced.
Among the present invention in the compositions taurine absorption and the transhipment of zinc gluconate had facilitation, zinc and the plumbous antagonism that absorbs in small intestinal when replenishing zinc element, can effectively reduce plumbous absorption.Taurine can promote vitamin C and B
1Fat-soluble little absorption of giving birth to element, and vitamin C and B
1All can effectively reduce Pb-B, and make lead tolerance reduction in liver, the kidney and other organs.Fructus Mume extract is rich in organic acid, can effectively reduce plumbous absorption.The present composition is the ability antioxidation also, improves body immunity, has avoided using the loss that the Western medicine chelating agent causes trace element in the body, and the above-mentioned raw materials compatibility uses, can Synergistic.
The functional test result of the present composition shows to have the Plumbum removing of promotion effect.
The specific embodiment
The present invention is described further by embodiment.
Embodiment 1
Get Fructus Mume extract 400g, taurine 100g, zinc gluconate 100g, vitamin B
15g, vitamin C 40g adds purified water 1000g, is stirred to dissolving fully, embedding, sterilization promptly gets oral solutions.
Embodiment 2
Get Fructus Mume extract 1400g, taurine 500g, zinc gluconate 300g, vitamin B
120g, vitamin C 300g adds purified water 5000g, is stirred to dissolving fully, embedding, sterilization promptly gets oral solutions.
Embodiment 3
Get Fructus Mume extract 700g, taurine 300g, zinc gluconate 200g, vitamin B
110g, vitamin C 190g adds purified water 2000g, is stirred to dissolving fully, embedding, sterilization promptly gets oral solutions.
Embodiment 4
Get Fructus Mume extract 500g, taurine 300g, zinc gluconate 170g, vitamin B
19g, vitamin C 160g adds purified water 1200g, is stirred to dissolving fully, embedding, sterilization promptly gets oral solutions.
Embodiment 5
Get Fructus Mume extract 490g, taurine 240g, zinc gluconate 330g, vitamin B
111g, vitamin C 153g adds mannitol 1300g, makes tablet according to a conventional method, promptly.
Embodiment 6
Get Fructus Mume extract 900g, taurine 240g, zinc gluconate 330g, vitamin B
111g, vitamin C 153g, lactose 1600g, evenly mixed, make granule according to a conventional method, promptly.
Embodiment 7
Get Fructus Mume extract 830g, taurine 360g, zinc gluconate 240g, vitamin B
17g, vitamin C 112g, dextrin 1100g, evenly mixed, make granule according to a conventional method, promptly.
Embodiment 8
Get Fructus Mume extract 592g, taurine 457g, zinc gluconate 185g, vitamin B
18g, Catergen 31g, starch 1600g, evenly mixed, make capsule according to a conventional method, promptly.
Claims (5)
1, a kind of compositions with promotion lead-expelling function is characterized in that being made by the raw material of following weight portion:
Fructus Mume extract 400-1400 taurine 100-500 zinc gluconate 100-300
Vitamin B
15-20 vitamin C 40-300.
2, the preparation of compositions method that has lead-expelling function according to claim 1 is characterized in that adding suitable pharmaceutical necessities and makes a kind of dosage form in tablet, capsule, oral solutions, the granule.
3, as having the preparation of compositions method of lead-expelling function as described in the claim 2, it is characterized in that pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, hydroxypropyl cellulose, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, Polyethylene Glycol, potassium sorbate, Aspartane, ethyl hydroxybenzoate, propyl hydroxybenzoate, cane sugar powder, micropowder silica gel, citric acid, Pulvis Talci, magnesium stearate, stevioside, milk-taste essence, xanthan gum, carrageenan wherein one or more.
4, have lead-expelling function preparation of compositions method as claimed in claim 1 or 2, it is characterized in that comprising the steps:
Get Fructus Mume extract, taurine, zinc gluconate, vitamin C, vitamin B in proportion
1, add filler, correctives is standby, make tablet according to a conventional method and get final product.
5,, it is characterized in that also can adding filler and can be selected from xylitol, mannitol, the lactose one or more as having the preparation of compositions method of lead-expelling function as described in the claim 4; Correctives can be selected from one or more of Aspartane, stevioside, milk-taste essence, citric acid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101799613A CN101461855A (en) | 2007-12-20 | 2007-12-20 | Composition with function for promoting lead-expelling and method for preparing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101799613A CN101461855A (en) | 2007-12-20 | 2007-12-20 | Composition with function for promoting lead-expelling and method for preparing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101461855A true CN101461855A (en) | 2009-06-24 |
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ID=40802790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101799613A Pending CN101461855A (en) | 2007-12-20 | 2007-12-20 | Composition with function for promoting lead-expelling and method for preparing the same |
Country Status (1)
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| CN (1) | CN101461855A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102335256A (en) * | 2011-09-22 | 2012-02-01 | 浙江省中药研究所有限公司 | Chinese medicinal herb preparation for lead removing treatment and preparation method thereof |
| CN102726721A (en) * | 2011-12-21 | 2012-10-17 | 聂存良 | Balanced trace element lead-removing oral liquid |
| CN107006863A (en) * | 2017-04-13 | 2017-08-04 | 广东太阳神集团有限公司 | It is a kind of to promote health food of lead discharging and preparation method thereof |
| CN107028937A (en) * | 2017-04-27 | 2017-08-11 | 河南科技大学 | A kind of composition and preparation with lead-expelling function |
| CN108902810A (en) * | 2018-07-19 | 2018-11-30 | 深圳市博奥生物科技有限公司 | A kind of oral solution and preparation method thereof |
| CN112386644A (en) * | 2020-10-19 | 2021-02-23 | 军事科学院军事医学研究院环境医学与作业医学研究所 | Composition for enhancing immunity and application |
-
2007
- 2007-12-20 CN CNA2007101799613A patent/CN101461855A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102335256A (en) * | 2011-09-22 | 2012-02-01 | 浙江省中药研究所有限公司 | Chinese medicinal herb preparation for lead removing treatment and preparation method thereof |
| CN102726721A (en) * | 2011-12-21 | 2012-10-17 | 聂存良 | Balanced trace element lead-removing oral liquid |
| CN107006863A (en) * | 2017-04-13 | 2017-08-04 | 广东太阳神集团有限公司 | It is a kind of to promote health food of lead discharging and preparation method thereof |
| CN107028937A (en) * | 2017-04-27 | 2017-08-11 | 河南科技大学 | A kind of composition and preparation with lead-expelling function |
| CN108902810A (en) * | 2018-07-19 | 2018-11-30 | 深圳市博奥生物科技有限公司 | A kind of oral solution and preparation method thereof |
| CN112386644A (en) * | 2020-10-19 | 2021-02-23 | 军事科学院军事医学研究院环境医学与作业医学研究所 | Composition for enhancing immunity and application |
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| C06 | Publication | ||
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090624 |