CN101453986A - 通过微研磨和在微晶种上结晶生产结晶有机微粒组合物的方法和设备及其应用 - Google Patents
通过微研磨和在微晶种上结晶生产结晶有机微粒组合物的方法和设备及其应用 Download PDFInfo
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Abstract
Description
操作编号 | 天 | 负荷的晶种(%) | Mv(um) | 95%<(um) |
7A | 5 | 0.5 | 77 | 179.1 |
7B | 13 | 0.5 | 72 | 158.5 |
7C | 10 | 2 | 52 | 120.5 |
实施例12 | 实施例11 | |
批体积 | 260L | 240L |
搅拌器叶片端速(m/s) | 4 | 4 |
晶种(%) | 10 | 3 |
晶种装料时间(min.) | 8 | 4 |
冷却时间(hr) | 3 | 10 |
周转时间(min.) | 18 | 9 |
能量装置 | 超声发生器(800W) | 双三通 |
丙酮洗涤 | 3x浆料 | 3x浆料 |
mv(um) | 11.6 | 20.61 |
95%<(um) | 23.8 | 40.34 |
表面积,m2/g | 0.5686 | 0.4019 |
凝聚 | 无 | 无 |
Claims (23)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78216906P | 2006-03-14 | 2006-03-14 | |
US60/782,169 | 2006-03-14 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2012101320506A Division CN102631323A (zh) | 2006-03-14 | 2007-03-12 | 通过微研磨和在微晶种上结晶生产结晶有机微粒组合物的方法和设备及其应用 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN101453986A true CN101453986A (zh) | 2009-06-10 |
Family
ID=38510201
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2007800091009A Pending CN101453986A (zh) | 2006-03-14 | 2007-03-12 | 通过微研磨和在微晶种上结晶生产结晶有机微粒组合物的方法和设备及其应用 |
CN2012101320506A Pending CN102631323A (zh) | 2006-03-14 | 2007-03-12 | 通过微研磨和在微晶种上结晶生产结晶有机微粒组合物的方法和设备及其应用 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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CN2012101320506A Pending CN102631323A (zh) | 2006-03-14 | 2007-03-12 | 通过微研磨和在微晶种上结晶生产结晶有机微粒组合物的方法和设备及其应用 |
Country Status (12)
Country | Link |
---|---|
US (1) | US20090087492A1 (zh) |
EP (1) | EP1993513A4 (zh) |
JP (1) | JP5197564B2 (zh) |
KR (1) | KR20080110807A (zh) |
CN (2) | CN101453986A (zh) |
AU (1) | AU2007226626B8 (zh) |
BR (1) | BRPI0708470A2 (zh) |
CA (1) | CA2642504A1 (zh) |
IL (1) | IL193395A0 (zh) |
MX (1) | MX2008010707A (zh) |
TW (1) | TW200810789A (zh) |
WO (1) | WO2007106768A2 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108031142A (zh) * | 2017-12-13 | 2018-05-15 | 上海合全药物研发有限公司 | 一种简化的利用湿磨来制备大量微晶种的装置及方法 |
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- 2007-03-12 KR KR1020087024984A patent/KR20080110807A/ko not_active Application Discontinuation
- 2007-03-12 US US12/282,043 patent/US20090087492A1/en not_active Abandoned
- 2007-03-12 WO PCT/US2007/063785 patent/WO2007106768A2/en active Application Filing
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- 2007-03-12 CN CNA2007800091009A patent/CN101453986A/zh active Pending
- 2007-03-12 CN CN2012101320506A patent/CN102631323A/zh active Pending
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108031142A (zh) * | 2017-12-13 | 2018-05-15 | 上海合全药物研发有限公司 | 一种简化的利用湿磨来制备大量微晶种的装置及方法 |
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US20090087492A1 (en) | 2009-04-02 |
AU2007226626B8 (en) | 2012-10-18 |
EP1993513A2 (en) | 2008-11-26 |
CA2642504A1 (en) | 2007-09-20 |
JP5197564B2 (ja) | 2013-05-15 |
WO2007106768A2 (en) | 2007-09-20 |
KR20080110807A (ko) | 2008-12-19 |
WO2007106768A3 (en) | 2008-10-02 |
JP2009529982A (ja) | 2009-08-27 |
IL193395A0 (en) | 2009-05-04 |
BRPI0708470A2 (pt) | 2011-05-31 |
CN102631323A (zh) | 2012-08-15 |
AU2007226626A1 (en) | 2007-09-20 |
AU2007226626B2 (en) | 2012-06-21 |
EP1993513A4 (en) | 2012-06-27 |
MX2008010707A (es) | 2009-01-27 |
TW200810789A (en) | 2008-03-01 |
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