CN101450074A - 一种明显改善胃肠道功能、防治便秘的组合物 - Google Patents
一种明显改善胃肠道功能、防治便秘的组合物 Download PDFInfo
- Publication number
- CN101450074A CN101450074A CNA2007101136992A CN200710113699A CN101450074A CN 101450074 A CN101450074 A CN 101450074A CN A2007101136992 A CNA2007101136992 A CN A2007101136992A CN 200710113699 A CN200710113699 A CN 200710113699A CN 101450074 A CN101450074 A CN 101450074A
- Authority
- CN
- China
- Prior art keywords
- vitamin
- compositions
- constipation
- calcium carbonate
- gastrointestinal function
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 36
- 210000001035 gastrointestinal tract Anatomy 0.000 title abstract description 4
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 26
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 26
- 206010010774 Constipation Diseases 0.000 claims abstract description 23
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 13
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 13
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 13
- 239000011718 vitamin C Substances 0.000 claims abstract description 13
- 239000008267 milk Substances 0.000 claims abstract description 12
- 235000013336 milk Nutrition 0.000 claims abstract description 12
- 210000004080 milk Anatomy 0.000 claims abstract description 12
- 238000002360 preparation method Methods 0.000 claims abstract description 11
- 235000010216 calcium carbonate Nutrition 0.000 claims abstract 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims description 38
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims description 19
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims description 19
- 239000007910 chewable tablet Substances 0.000 claims description 13
- 229940068682 chewable tablet Drugs 0.000 claims description 13
- 230000007661 gastrointestinal function Effects 0.000 claims description 12
- 239000000796 flavoring agent Substances 0.000 claims description 11
- 235000019634 flavors Nutrition 0.000 claims description 11
- 239000002552 dosage form Substances 0.000 claims description 8
- 239000008187 granular material Substances 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 239000002775 capsule Substances 0.000 claims description 4
- 239000007919 dispersible tablet Substances 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- 238000012856 packing Methods 0.000 claims description 4
- 239000002994 raw material Substances 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 2
- 238000001514 detection method Methods 0.000 abstract description 2
- 235000013305 food Nutrition 0.000 abstract 2
- HEBKCHPVOIAQTA-NGQZWQHPSA-N d-xylitol Chemical compound OC[C@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-NGQZWQHPSA-N 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 description 7
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 6
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 230000033228 biological regulation Effects 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 241000186016 Bifidobacterium bifidum Species 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 3
- 229920001353 Dextrin Polymers 0.000 description 3
- 239000004375 Dextrin Substances 0.000 description 3
- 239000011575 calcium Substances 0.000 description 3
- 229910052791 calcium Inorganic materials 0.000 description 3
- 230000013872 defecation Effects 0.000 description 3
- 235000019425 dextrin Nutrition 0.000 description 3
- 235000019359 magnesium stearate Nutrition 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 2
- 241000607142 Salmonella Species 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000009977 dual effect Effects 0.000 description 2
- 230000007674 genetic toxicity Effects 0.000 description 2
- 231100000025 genetic toxicology Toxicity 0.000 description 2
- 235000013402 health food Nutrition 0.000 description 2
- 229920001542 oligosaccharide Polymers 0.000 description 2
- 150000002482 oligosaccharides Chemical class 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 241000609240 Ambelania acida Species 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 241000186000 Bifidobacterium Species 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- 206010006956 Calcium deficiency Diseases 0.000 description 1
- 241000193403 Clostridium Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000186660 Lactobacillus Species 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 229930003270 Vitamin B Natural products 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 239000010905 bagasse Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 235000019621 digestibility Nutrition 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229940039696 lactobacillus Drugs 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 235000018291 probiotics Nutrition 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000003716 rejuvenation Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000014860 sensory perception of taste Effects 0.000 description 1
- -1 this also helps Substances 0.000 description 1
- 231100000041 toxicology testing Toxicity 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 229920001221 xylan Polymers 0.000 description 1
- 150000004823 xylans Chemical class 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2007101136992A CN101450074B (zh) | 2007-11-30 | 2007-11-30 | 一种明显改善胃肠道功能、防治便秘的组合物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2007101136992A CN101450074B (zh) | 2007-11-30 | 2007-11-30 | 一种明显改善胃肠道功能、防治便秘的组合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101450074A true CN101450074A (zh) | 2009-06-10 |
CN101450074B CN101450074B (zh) | 2012-03-14 |
Family
ID=40732672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2007101136992A Active CN101450074B (zh) | 2007-11-30 | 2007-11-30 | 一种明显改善胃肠道功能、防治便秘的组合物 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101450074B (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8999313B2 (en) | 2012-09-11 | 2015-04-07 | Norgine Bv | Compositions |
US9592252B2 (en) | 2011-03-11 | 2017-03-14 | Norgine Bv | Colonoscopy—preparation |
CN108925989A (zh) * | 2018-08-04 | 2018-12-04 | 安徽全康药业有限公司 | 一种预防肠胃疾病益生菌咀嚼片及其制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1559415A (zh) * | 2004-03-12 | 2005-01-05 | 北京奥信通科技发展有限公司 | 低聚木糖在制备治疗肠道功能紊乱的药物中的应用 |
-
2007
- 2007-11-30 CN CN2007101136992A patent/CN101450074B/zh active Active
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9592252B2 (en) | 2011-03-11 | 2017-03-14 | Norgine Bv | Colonoscopy—preparation |
US10646512B2 (en) | 2011-03-11 | 2020-05-12 | Norgine Bv | Colonoscopy - preparation |
US10780112B2 (en) | 2011-03-11 | 2020-09-22 | Norgine Bv | Colonoscopy-preparation |
US10792306B2 (en) | 2011-03-11 | 2020-10-06 | Norgine Bv | Colonoscopy—preparation |
US11529368B2 (en) | 2011-03-11 | 2022-12-20 | Norgine Bv | Colonoscopy—preparation |
US8999313B2 (en) | 2012-09-11 | 2015-04-07 | Norgine Bv | Compositions |
US9326969B2 (en) | 2012-09-11 | 2016-05-03 | Norgine Bv | Compositions |
US9707297B2 (en) | 2012-09-11 | 2017-07-18 | Norgine Bv | Compositions |
US10016504B2 (en) | 2012-09-11 | 2018-07-10 | Norgine Bv | Compositions |
US10918723B2 (en) | 2012-09-11 | 2021-02-16 | Norgine Bv | Colon cleansing compositions and methods of use |
CN108925989A (zh) * | 2018-08-04 | 2018-12-04 | 安徽全康药业有限公司 | 一种预防肠胃疾病益生菌咀嚼片及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
CN101450074B (zh) | 2012-03-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2559755C (en) | Dietary supplement and method for treating digestive system-related disorders | |
CN104524110A (zh) | 一种具有健脾祛湿作用的中药组合物 | |
CN112544920A (zh) | 一种改善便秘的组合物及其制备方法 | |
KR20160026916A (ko) | 다기능성 조성물 및 이의 제조 방법과 용도 | |
CN101416747A (zh) | 一种富含膳食纤维的固体低能量食品及其制备方法 | |
CN102302211A (zh) | 一种保健饮品 | |
CN107198246A (zh) | 一种保健组合物与一种保健制剂 | |
KR102014675B1 (ko) | 과립형 건강기능식품의 제조방법 | |
CN101450074B (zh) | 一种明显改善胃肠道功能、防治便秘的组合物 | |
CN103689748B (zh) | 一种具有调节肠胃道功能,防治便秘的即冲型饮品 | |
KR101687558B1 (ko) | 천연재료 추출물을 유효성분으로 하는 변비 및 숙변 개선용 조성물 및 그의 제조방법 | |
KR100998991B1 (ko) | 장용성 결명자 분말 과립 및 이를 함유하는 변비 개선용조성물 | |
KR100644149B1 (ko) | 사하제 | |
CN104305229B (zh) | 一种石斛膳食纤维食品及其加工方法 | |
KR100484428B1 (ko) | 변비 개선용 건강 보조 식품 | |
CN101468029B (zh) | 含双果糖酐的组合物及其用途 | |
CN106938021A (zh) | 治疗牛前胃迟缓和瘤胃膨胀的中药组合物及其制备方法 | |
CN101589806A (zh) | 一种富含膳食纤维和聚乙二醇的固体低能量食品及其制备方法 | |
Widjanarko et al. | Laxative potential of the konjac flour (Amorphophallus muelleri Blume) in treatment of loperamide induced constipation on Sprague Dawley rats | |
CN104208692A (zh) | 组合物在制备通便清肠产品中的应用 | |
CN110074306A (zh) | 一种菊粉泡腾片固体饮料及其制作方法 | |
KR20040024008A (ko) | 변비 개선용 건강식품 조성물 | |
KR100615967B1 (ko) | 변비개선 효과를 갖는 건강보조식품 | |
KR102609638B1 (ko) | 미역귀 추출물을 유효성분으로 포함하는 장내 균총 개선용 조성물 | |
CN102698144B (zh) | 一种治疗胃胀的中药组合物 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: SHANDONG MINGREN FURUIDA PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: LING PEIXUE Effective date: 20120309 |
|
C41 | Transfer of patent application or patent right or utility model | ||
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 250014 JINAN, SHANDONG PROVINCE TO: 250104 JINAN, SHANDONG PROVINCE |
|
TR01 | Transfer of patent right |
Effective date of registration: 20120309 Address after: 250104 Ji'nan hi tech District Road No. 3333 Patentee after: Shandong Mingren Furuida Pharmaceutical Co.,Ltd Address before: 250014 No. 264 mountain road, Shandong, Ji'nan Patentee before: Ling Peixue |
|
C53 | Correction of patent for invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Zhang Ling Inventor after: Ling Peixue Inventor after: Wang Guoqiang Inventor after: Wang Ni Inventor after: Shang Lixia Inventor after: Jia Meichun Inventor after: Wu Weiqun Inventor after: Shi Yanzeng Inventor after: Kuang Chengyu Inventor before: Zhang Ling Inventor before: Shi Yanzeng Inventor before: Zhang Hu Inventor before: Kuang Chengyu Inventor before: Sun Yingfa Inventor before: Ling Peixue Inventor before: Qu Yanwei Inventor before: Wang Guoqiang Inventor before: Yang Yankun Inventor before: Wang Ni Inventor before: Shang Lixia Inventor before: Jia Meichun Inventor before: Wu Weiqun |
|
COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: ZHANG LING LING PEIXUE QU YANWEI WANG GUOQIANG YANG YANKUN WANG NI SHANG LIXIA JIA MEICHUN WU WEIQUN SHI YANZENG ZHANG HU KUANG CHENGYU SUN YINGFA TO: ZHANG LING LING PEIXUE WANG GUOQIANG WANG NI SHANG LIXIA JIA MEICHUN WU WEIQUN SHI YANZENG KUANG CHENGYU |
|
C56 | Change in the name or address of the patentee | ||
CP01 | Change in the name or title of a patent holder |
Address after: Hi tech District Ji'nan city Shandong province 250104 Road No. 3333 Patentee after: Shandong Mingren Furuida Pharmaceutical Co., Ltd. Address before: Hi tech District Ji'nan city Shandong province 250104 Road No. 3333 Patentee before: Shandong Mingren Furuida Pharmaceutical Co.,Ltd |