CN101448957A - 用于检测核酸、核酸的甲基化状态和突变体的包含信号对和疏水性核苷酸、无茎信标的寡核苷酸 - Google Patents

用于检测核酸、核酸的甲基化状态和突变体的包含信号对和疏水性核苷酸、无茎信标的寡核苷酸 Download PDF

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CN101448957A
CN101448957A CNA200780017820XA CN200780017820A CN101448957A CN 101448957 A CN101448957 A CN 101448957A CN A200780017820X A CNA200780017820X A CN A200780017820XA CN 200780017820 A CN200780017820 A CN 200780017820A CN 101448957 A CN101448957 A CN 101448957A
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oligonucleotide analogs
signal
oligonucleotide
nucleotide
nucleic acid
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尤尔弗·本奇·克里斯滕森
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays

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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNA200780017820XA 2006-03-16 2007-03-16 用于检测核酸、核酸的甲基化状态和突变体的包含信号对和疏水性核苷酸、无茎信标的寡核苷酸 Pending CN101448957A (zh)

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DKPA200600379 2006-03-16
DKPA200600379 2006-03-16

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CN101448957A true CN101448957A (zh) 2009-06-03

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CNA200780017820XA Pending CN101448957A (zh) 2006-03-16 2007-03-16 用于检测核酸、核酸的甲基化状态和突变体的包含信号对和疏水性核苷酸、无茎信标的寡核苷酸

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US (1) US8133984B2 (https=)
EP (1) EP2004847B1 (https=)
JP (1) JP5284112B2 (https=)
CN (1) CN101448957A (https=)
AU (1) AU2007224843A1 (https=)
CA (1) CA2645136C (https=)
DK (1) DK2004847T3 (https=)
NZ (1) NZ571966A (https=)
WO (1) WO2007104318A2 (https=)

Cited By (1)

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CN114286865A (zh) * 2019-05-13 2022-04-05 潘塔贝斯公司 检测变体核酸的解链温度方法、试剂盒和报告寡核苷酸

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DE102010012421B4 (de) 2009-03-23 2023-04-20 Vermicon Ag Verfahren zum spezifischen Nachweis von Mikroorganismen
WO2011032034A2 (en) 2009-09-10 2011-03-17 University Of Idaho Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting nucleic acids
JP5717169B2 (ja) * 2010-09-14 2015-05-13 国立大学法人名古屋大学 オリゴヌクレオチド及びその利用
WO2013013068A2 (en) 2011-07-19 2013-01-24 University Of Idaho Embodiments of a probe and method for targeting nucleic acids
US9127317B2 (en) 2012-03-02 2015-09-08 Winthrop-University Hospital Method for using probe based PCR detection to measure the levels of circulating demethylated β cell derived DNA as a measure of β cell loss in diabetes
CN102911111B (zh) * 2012-11-08 2014-06-11 齐鲁工业大学 一种咔唑苯甲醛缩对苯二胺双席夫碱及其制备方法
WO2017045689A1 (en) 2015-09-14 2017-03-23 Pentabase Aps Methods and materials for detection of mutations
EP3472355A4 (en) 2016-06-15 2020-07-29 Genecapture, Inc. COMPOSITIONS, METHODS AND DEVICES INCLUDING ROD LOOP MOLECULES-SENSORS
CN108827935B (zh) * 2018-06-08 2021-09-07 南京师范大学 一种基于金纳米孔阵列的dna甲基化表面增强拉曼散射光谱检测方法及其应用
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
CN110261964B (zh) * 2019-07-01 2021-06-04 国检中心深圳珠宝检验实验室有限公司 一种用于光纤光谱仪的光纤头
KR20230034959A (ko) * 2020-06-29 2023-03-10 펜타베이스 에이피에스 메틸화 상태의 검출

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Publication number Priority date Publication date Assignee Title
CN114286865A (zh) * 2019-05-13 2022-04-05 潘塔贝斯公司 检测变体核酸的解链温度方法、试剂盒和报告寡核苷酸

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JP5284112B2 (ja) 2013-09-11
JP2009529337A (ja) 2009-08-20
WO2007104318A3 (en) 2008-03-20
CA2645136A1 (en) 2007-09-20
CA2645136C (en) 2017-09-19
US20100068704A1 (en) 2010-03-18
AU2007224843A1 (en) 2007-09-20
US8133984B2 (en) 2012-03-13
WO2007104318A2 (en) 2007-09-20
EP2004847B1 (en) 2017-05-03
NZ571966A (en) 2011-09-30
DK2004847T3 (en) 2017-08-21
EP2004847A2 (en) 2008-12-24

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