CN101442997B - 雷沙吉兰用于治疗多动腿综合征 - Google Patents

雷沙吉兰用于治疗多动腿综合征 Download PDF

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Publication number
CN101442997B
CN101442997B CN2007800117920A CN200780011792A CN101442997B CN 101442997 B CN101442997 B CN 101442997B CN 2007800117920 A CN2007800117920 A CN 2007800117920A CN 200780011792 A CN200780011792 A CN 200780011792A CN 101442997 B CN101442997 B CN 101442997B
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China
Prior art keywords
propargyl
aminoidan
patient
acceptable salt
pharmacy
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Expired - Fee Related
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CN2007800117920A
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English (en)
Chinese (zh)
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CN101442997A (zh
Inventor
埃朗·布拉歌
鲁斯·莱威
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Teva Pharmaceutical Industries Ltd
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Teva Pharmaceutical Industries Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN2007800117920A 2006-04-03 2007-03-30 雷沙吉兰用于治疗多动腿综合征 Expired - Fee Related CN101442997B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78861706P 2006-04-03 2006-04-03
US60/788,617 2006-04-03
PCT/US2007/008261 WO2007117431A2 (en) 2006-04-03 2007-03-30 Use of rasagiline for the treatment of restless legs syndrome

Publications (2)

Publication Number Publication Date
CN101442997A CN101442997A (zh) 2009-05-27
CN101442997B true CN101442997B (zh) 2012-11-14

Family

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CN2007800117920A Expired - Fee Related CN101442997B (zh) 2006-04-03 2007-03-30 雷沙吉兰用于治疗多动腿综合征

Country Status (11)

Country Link
US (16) US8946300B2 (enExample)
EP (1) EP2007369A4 (enExample)
JP (2) JP5769923B2 (enExample)
CN (1) CN101442997B (enExample)
AU (1) AU2007235517B2 (enExample)
CA (1) CA2646250A1 (enExample)
IL (5) IL194328A (enExample)
MX (1) MX2008012781A (enExample)
NZ (1) NZ571591A (enExample)
WO (1) WO2007117431A2 (enExample)
ZA (1) ZA200808409B (enExample)

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EP1892233A1 (de) 2006-08-18 2008-02-27 Ratiopharm GmbH Neue Salze des Wirkstoffs Rasagilin
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KR20140090996A (ko) 2011-10-10 2014-07-18 테바 파마슈티컬 인더스트리즈 리미티드 R(+)-n-폼일-프로파길-아미노인단
AU2012323351A1 (en) 2011-10-10 2014-05-22 Teva Pharmaceutical Industries Ltd. R(+)-N-methyl-propargyl-aminoindan
ES2655676T3 (es) * 2012-01-12 2018-02-21 Pharma Two B Ltd. Terapia de combinación con dosis fijas para tratar la enfermedad de Parkinson
JP2015529196A (ja) 2012-08-17 2015-10-05 テバ ファーマシューティカル インダストリーズ リミティド ラサギリンの非経口製剤
ES2983441T3 (es) 2018-02-15 2024-10-23 Intrabio Ltd Acetil-leucina para su uso en el tratamiento de síndrome de las piernas inquietas

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IL265866A (en) 2019-06-30
US20190142766A1 (en) 2019-05-16
IL234749A0 (en) 2014-11-30
US20160317471A1 (en) 2016-11-03
US20210023026A1 (en) 2021-01-28
US20190262284A1 (en) 2019-08-29
US12310929B2 (en) 2025-05-27
US20210137852A1 (en) 2021-05-13
CN101442997A (zh) 2009-05-27
JP5769923B2 (ja) 2015-08-26
US20180169038A1 (en) 2018-06-21
WO2007117431A3 (en) 2008-11-27
US20210251921A1 (en) 2021-08-19
JP2013166772A (ja) 2013-08-29
IL275890A (en) 2020-08-31
US8946300B2 (en) 2015-02-03
CA2646250A1 (en) 2007-10-18
NZ571591A (en) 2011-09-30
AU2007235517B2 (en) 2013-01-31
US20200323796A1 (en) 2020-10-15
JP2009534312A (ja) 2009-09-24
IL247850A0 (en) 2016-11-30
EP2007369A2 (en) 2008-12-31
US20190365674A1 (en) 2019-12-05
US20210386690A1 (en) 2021-12-16
MX2008012781A (es) 2008-10-14
US20200206161A1 (en) 2020-07-02
US20070232700A1 (en) 2007-10-04
US20200093758A1 (en) 2020-03-26
ZA200808409B (en) 2009-12-30
US20150080441A1 (en) 2015-03-19
WO2007117431A2 (en) 2007-10-18
EP2007369A4 (en) 2009-07-01
US20170360723A1 (en) 2017-12-21
IL194328A (en) 2017-11-30
US20190000780A1 (en) 2019-01-03
AU2007235517A1 (en) 2007-10-18

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