CN101416929B - Gargle - Google Patents

Gargle Download PDF

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Publication number
CN101416929B
CN101416929B CN2008101824592A CN200810182459A CN101416929B CN 101416929 B CN101416929 B CN 101416929B CN 2008101824592 A CN2008101824592 A CN 2008101824592A CN 200810182459 A CN200810182459 A CN 200810182459A CN 101416929 B CN101416929 B CN 101416929B
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CN
China
Prior art keywords
portions
collutory
gargle
parts
patient
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Expired - Fee Related
Application number
CN2008101824592A
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Chinese (zh)
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CN101416929A (en
Inventor
曹婷
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Individual
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Individual
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Priority to CN2008101824592A priority Critical patent/CN101416929B/en
Publication of CN101416929A publication Critical patent/CN101416929A/en
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Publication of CN101416929B publication Critical patent/CN101416929B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a gargle which is prepared by materials with the following weight proportions: 3 portions to 5 portions of honeysuckle, 0.5 portion to 1.5 portions of peppermint, 0.1 portion to 0.3 portion of pepper, 4 portions to 8 portions of radix notoginseng, 0.1 portion to 0.5 portion of borneol, 3 portions to 7 portions of wild chrysanthemum flower, 5 portions to 11 portions of green tea, 3 portions to 5 portions of sweetening chrysanthemum and 20 portions to 100 portions of water. The gargle has the advantages of lower cost and better safety, and even when being swallowed, the gargle does no harm to patients. The gargle also has obvious disinfection effect to the oral cavity, and is applicable for large-scale promotion in clinics.

Description

A kind of collutory
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of collutory that is used for oral disinfecting.
Background technology
When clinical oral was performed the operation, the patient directly accomplished to undergo surgery on the operating chair at present.Because part patient oral hygiene is not fine, oral cavity bacterium is more, when operation or cause the infection of wound after the operation easily.Sterilize although can take antibiont, the antibiotic price is generally more expensive on the one hand, buys antibiotic and brings new medical treatment burden to the patient; Second aspect is that the infection of wound brings very big inconvenience to the patient.
In addition, patient's oral hygiene keeps with great difficulty not having implication, because operation on oral cavity need open face for a long time, so bring very big unhappy sense for easily doctor and assistant thereof.
At present, clinically be to use the hydrogen peroxide after the dilution to gargle, but hydrogen peroxide is a kind of chemical substance more, if concentration adjustment with great difficulty the boil on the nape opposite the mouth transmucosal do not damage, if the patient swallows accidentally, then easily esophagus is damaged.And it also can't solve the bigger problem of part patient implication.
Summary of the invention
The purpose of this invention is to provide a kind of collutory that is used for oral disinfecting.
In order to realize purpose of the present invention, the invention provides a kind of collutory, it is to be made by following materials by weight: Flos Lonicerae 3-5 part, Herba Menthae 0.5-1.5 part, Pericarpium Zanthoxyli 0.1-0.3 part, Radix Notoginseng 4-8 part, Borneolum Syntheticum 0.1-0.5 part, Flos Chrysanthemi Indici 3-7 part, green tea 5-11 part, Folium Stevlae Rebaudianae 3-5 part and water 20-100 part.
Preferably, described collutory is to be made by following materials by weight: 50 parts in 4 parts of Flos Loniceraes, 1 part of Herba Menthae, 0.2 part in Pericarpium Zanthoxyli, 5 parts of Radix Notoginseng, 0.2 part of Borneolum Syntheticum, 4 parts of Flos Chrysanthemi Indicis, 7 parts of green tea, 4 parts of Folium Stevlae Rebaudianae and water.
Collutory of the present invention is to be made by very cheap material entirely, so cost is comparatively cheap, and all composition all is a natural material, and safety is better, can not damage the patient even swallow also.Owing to used materials such as green tea, Herba Menthae, Borneolum Syntheticum in the collutory, patient's mouthfeel and sense of taste reaction in use is good.In addition,, after gargling, have little picotement, thereby reduced before operation under the situation of injection anaesthetic, patient's pain when syringe needle penetrates muscle in the oral cavity owing to used an amount of Pericarpium Zanthoxyli in the collutory of the present invention.Collutory oral disinfecting effect of the present invention is obvious, is suitable for large-scale promotion clinically.
The specific embodiment
Embodiment 1:
Take by weighing Flos Lonicerae 4g, Herba Menthae 1g, Pericarpium Zanthoxyli 0.2g, Radix Notoginseng 5g, Borneolum Syntheticum 0.2g, Flos Chrysanthemi Indici 4g, green tea 7g, Folium Stevlae Rebaudianae 4g and water 50g, place in the flask of sealing.Heating is 5 hours under 30 ℃ water-bath, filters, and collects filtrate promptly.
When the patient uses collutory, generally once use 10-20ml.When using collutory of the present invention, can before operation, repeatedly gargle, also can once suck several minutes.Collutory can be told, and also can directly swallow.
Experimental example 1: bacteriostatic test
Adopt filter paper method classical in this area to carry out bacteriostatic test, wherein:
1. material
1.1 for the examination strain
Staphylococcus aureus (Staphylococcus aureus) ATCC 25923, Candida albicans (Candida albicans) ACTT 12228 is all available from Chinese biological goods calibrating institute.
1.2 culture fluid
Nutrient agar and nutrient broth are all available from BeiJing ZhongKe's space in morning experimental facilities company limited.
1.3 test method
Staphylococcus aureus and Candida albicans are inoculated on the agar plate nutritional solution plane, evenly gather during inoculation.The aseptic circular filter paper sheet of tweezer immerses the collutory among the embodiment 1, fully behind the dipping, is attached on the agar plate nutritional solution plane of inoculated bacteria.Agar plate placed in 37 ℃ the incubator incubation 24 hours.Measure the diameter of antibacterial ring.Measuring 3 times averages.
1.4 result
The average diameter of the antibacterial ring of staphylococcus aureus is 11.23mm, and the average diameter of the antibacterial ring of Candida albicans is 6.87mm, shows that collutory of the present invention has tangible fungistatic effect.
Experimental example 2: patient's mouthfeel and sense of taste
10 patients before please operation on oral cavity use the collutory of embodiment 1.10 patients all represent the good mouthfeel of this collutory.Wherein have 6 to be that the patient just swallows under the situation of not doing any suggestion or hint voluntarily.After asking 10 patients all to swallow, represent that all the sense of taste of this collutory is good.
Experimental example 3: the pain during the patient infusion anaesthetic
The collutory that please preceding 5 patients of operation on oral cavity use embodiment 1, and the record syringe needle thrusts the pain of muscle in a flash the time.5 patients all are illustrated in and sting the fashionable insufferable pain that do not produce.
Usually in injection during anaesthetic, syringe needle thrust muscle in a flash the time patient tend to trained reflex ground moving-head or swing.Above-mentioned 5 patients head when the injection anaesthetic does not move or swing, and this has also confirmed the above-mentioned effect of collutory of the present invention.

Claims (2)

1. a collutory is characterized in that it is to be made by following materials by weight: Flos Lonicerae 3-5 part, Herba Menthae 0.5-1.5 part, Pericarpium Zanthoxyli 0.1-0.3 part, Radix Notoginseng 4-8 part, Borneolum Syntheticum 0.1-0.5 part, Flos Chrysanthemi Indici 3-7 part, green tea 5-11 part, Folium Stevlae Rebaudianae 3-5 part and water 20-100 part.
2. collutory according to claim 1 is characterized in that it is to be made by following materials by weight: 50 parts in 4 parts of Flos Loniceraes, 1 part of Herba Menthae, 0.2 part in Pericarpium Zanthoxyli, 5 parts of Radix Notoginseng, 0.2 part of Borneolum Syntheticum, 4 parts of Flos Chrysanthemi Indicis, 7 parts of green tea, 4 parts of Folium Stevlae Rebaudianae and water.
CN2008101824592A 2008-12-08 2008-12-08 Gargle Expired - Fee Related CN101416929B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2008101824592A CN101416929B (en) 2008-12-08 2008-12-08 Gargle

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2008101824592A CN101416929B (en) 2008-12-08 2008-12-08 Gargle

Publications (2)

Publication Number Publication Date
CN101416929A CN101416929A (en) 2009-04-29
CN101416929B true CN101416929B (en) 2010-08-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008101824592A Expired - Fee Related CN101416929B (en) 2008-12-08 2008-12-08 Gargle

Country Status (1)

Country Link
CN (1) CN101416929B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106109345A (en) * 2016-08-17 2016-11-16 林少英 A kind of Chinese herbal toothpaste

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105288089A (en) * 2015-11-25 2016-02-03 严中明 Throat abscess treating pharmaceutical composition
CN105343470A (en) * 2015-11-25 2016-02-24 严中明 Traditional Chinese medicine composition for treating mouth floor cellulitis
CN105411914A (en) * 2015-12-01 2016-03-23 赵雅珺 Mouth wash
CN109528601B (en) * 2019-01-21 2021-07-16 谷筱玉 Compound traditional Chinese medicine mouth wash and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106109345A (en) * 2016-08-17 2016-11-16 林少英 A kind of Chinese herbal toothpaste

Also Published As

Publication number Publication date
CN101416929A (en) 2009-04-29

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
EE01 Entry into force of recordation of patent licensing contract

Assignee: Cao Ting

Assignor: Bao Jian (China) daily necessities Co., Ltd.

Contract record no.: 2010990000861

Denomination of invention: Liquid gargle and its preparation

Granted publication date: 20100825

License type: Exclusive License

Open date: 20090429

Record date: 20101028

EE01 Entry into force of recordation of patent licensing contract

Assignee: Bao Jian (China) daily necessities Co., Ltd.

Assignor: Cao Ting

Contract record no.: 2010990000861

Denomination of invention: Liquid gargle and its preparation

Granted publication date: 20100825

License type: Exclusive License

Open date: 20090429

Record date: 20101028

C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100825

Termination date: 20111208