CN101385505A - Chinese herbal medicine feed additive for preventing livestock and poultry diarrhea and preparation method thereof - Google Patents
Chinese herbal medicine feed additive for preventing livestock and poultry diarrhea and preparation method thereof Download PDFInfo
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- CN101385505A CN101385505A CNA2008101551970A CN200810155197A CN101385505A CN 101385505 A CN101385505 A CN 101385505A CN A2008101551970 A CNA2008101551970 A CN A2008101551970A CN 200810155197 A CN200810155197 A CN 200810155197A CN 101385505 A CN101385505 A CN 101385505A
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Abstract
The invention provides a Chinese medical herb feed additive used for protecting the livestock and poultry from diarrhea and a preparation method thereof. The Chinese medical herb feed additive is made from paulownia flower, purslane, water pepper, geranium wilfordii, sanguisorba, copperleaf herb and cactus. The weight proportion of the raw medicinal materials is: 29-35 parts of paulownia flower, 22-28 parts of purslane, 20-26 parts of water pepper, 17-23 parts of geranium wilfordii, 17-23 parts of sanguisorba, 13-17 parts of copperleaf herb and 8-12 parts of cactus. The Chinese medical herbs are treated by picking, washing, cutting, first aqueous extract, second aqueous extract, combining for decoction, concentrating, absorbing and parching, thereby obtaining the Chinese medical herb feed additive. Silicon dioxide is chosen as a sorbent in the production process and the addition of the silicon dioxide as one of the compositions of the Chinese medical herb feed additive weighs 85 percent of the raw medicinal materials. The Chinese medical herb feed additive has the efficacies of protecting the livestock and poultry from diarrhea as well as promoting growth and enhancing immunity, and has the advantages of high content of active ingredient, small dosage, easy use as well as nature, no residua, no drug resistance, etc.
Description
Technical field
The present invention relates to prevent the medicine of alimentary canal or disease of digestive system, be meant a kind of Chinese herbal feed additive of preventing livestock and poultry diarrhea and preparation method thereof that is used to especially.
Background technology
Livestock and poultry diarrhea is one of disease of digestive tract comparatively common in the livestock breeding industry, not only influence growth of animals or poultry speed, the medicine that has also increased simultaneously when disease takes place drops into expense, and also can cause livestock and poultry death under the serious situation, thereby brings very big economic loss to the raiser.At above situation, researching and developing a kind of feed addictive of livestock and poultry diarrhea, growth promotion, enhancing immunity that prevents has become a kind of important approach of such problem of solution.In the market, be used to prevent the feed addictive of livestock and poultry diarrhea mostly to be antibiotic, chemical synthetic drug etc., though these medicines can be brought into play certain curative effect, but also brought a series of insoluble problems such as antibody-resistant bacterium increase and medicament residue simultaneously, seriously restricted the sound development of livestock breeding industry.Although some Chinese herbal feed additives that are used to prevent livestock and poultry diarrhea appear in present domestic market, mostly be crude drug through the semifinished product that pulverizing makes, have defectives such as effective component content is low, consumption big, use inconvenience, effect is imprecise.
Summary of the invention
Technical problem to be solved by this invention just is the defective that exists at the feed addictive that is used to prevent livestock and poultry diarrhea at present, and a kind of safe, efficient, drug residue free, alternative antibiotic Chinese herbal feed additive and preparation method thereof are provided.The Chinese herbal feed additive of prevention livestock and poultry diarrhea of the present invention is by fortune paulownia flower, purslane, polygonum flaccidum, geranium wilfordii, garden burnet, acalypha copperleaf and cactus are prepared from, the weight proportion scope of crude drug is: fortune paulownia flower 29-35 part, purslane 22-28 part, polygonum flaccidum 20-26 part, geranium wilfordii 17-23 part, garden burnet 17-23 part, acalypha copperleaf 13-17 part and cactus 8-12 part, said herbal medicine is through picking, clean, cut medicine, water is carried first, secondary water is carried, collecting decoction, concentrate, absorption and oven dry make the Chinese herbal feed additive of prevention livestock and poultry diarrhea, adsorbent is selected silica for use in preparation process, and silica is 85% of crude drug weight as one of the composition of Chinese herbal feed additive addition.The crude drug of Chinese herbal feed additive weight proportion commonly used is: 10 parts in 32 parts of fortune paulownia flowers, 25 parts of purslanes, 23 parts of polygonum flaccidums, 20 parts of geranium wilfordiis, 20 parts of garden burnets, 15 parts of acalypha copperleafs and cactus.
It is the basis of investigating and putting into practice a large amount of that the present invention is used to prevent the Chinese herbal feed additive of livestock and poultry diarrhea, design function according to product requires more than 200 kinds of Chinese herbal medicines are screened, monarch, seven human emotions compatibility, eighteen incompatibilities nineteen counteraction scheduling theory according to traditional Chinese medicine, screening and the Chinese herbal medicine effective ingredients, the bacteriostasis that filter out extracted, verify is one by one finally determined prescription.The pharmacology situation of each component is in the prescription: (1) fortune paulownia flower: cold in nature for the flower of goatweed paulownia, and mildly bitter flavor.Clearing heat and detoxicating.Be used for bronchitis, acute tonsillitis, bacillary dysentery, chordapsus, acute conjunctivitis, mumps, furuncle.(2) purslane: clearing heat and detoxicating for the annual meat herbaceous plant of Portulacaceae, cooling blood and hemostasis.Be used for toxic-heat and blood stasis, the swollen sore for the treatment of of carbuncle, eczema, erysipelas, snake bite and insect sting is had blood in stool, diarrhea.Studies show that, purslane contains multiple chemical compositions with medical value such as abundant aliphatic acid, volatile oil, polysaccharide, amino acid, vitamin and mineral matter, has to strengthen the pharmacological action of waiting for a long time of immunity, reducing blood lipid, hypoglycemic, antibiotic, antitumor, anti-oxidant and health care.The purslane ethanol extract has significant inhibitory effect to Shigella shigae and dysentery characterized by blood in the stool bacillus, and various common food pollution bacterium such as Escherichia coli, salmonella, Shigella, staphylococcus aureus, proteus, bacillus subtilis etc. had stronger inhibitory action, even be diluted at 12.5% o'clock, still have certain bacteriostasis.In addition, to the lymphopoietic influence of rabbit, the result shows that purslane can significantly improve the lymphocytic multiplication capacity of rabbit to He Shengwen etc. by the research purslane.(3) polygonum flaccidum: flavor is hot, warm in nature, and main component is polygodial, confertifolin, polygonone, persicarin etc.Has expelling wind and removing dampness, blood stasis removing analgesic, removing toxicity for detumescence, killing parasites to relieve itshing effect.Be usually used in dysentery, gastroenteritis, diarrhoea clinically, rheumatic arthritis, treating swelling and pain by traumatic injury, functional uterine bleeding; Venomous snake bite is controlled in external application, skin eczema.(4) geranium wilfordii: hot, bitter, flat, return the liver,kidney,spleen warp, contain compositions such as volatile oil, Quercetin, tannin, gallic acid, butanedioic acid, Quercetin and glucoside thereof, have dispel the wind wet, the network that stimulates the menstrual flow, antidiarrheal dysentery effect.Its herb decoction has than the obvious suppression effect micrococcus catarrhalis, staphylococcus aureus, bacterium flexneri, beta chain coccus, pneumococcus etc.; The 68-1 of section strain of influenza A virus capital, Asia and the strain of parainfluenza virus I type celestial platform are also had than the obvious suppression effect.Be used for arthralgia due to wind-dampness clinically, numbness contracture, muscle creatine pain, dysentery more.(5) garden burnet: another name garden burnet, blood arrow grass etc., bitter, acid, puckery, cold nature.Contain zigu-glucoside, sangushsorbin A, B, E and gallic acid, tannin etc., have cooling blood and hemostasis, the sore effect is held back in detoxifcation, clinically be used to have blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, scald, carbuncle sore tumefacting virus.(6) acalypha copperleaf: bitter, puckery, cool in nature, the thoughts of returning home, lung channel.Be rich in alkaloid, glycosides displayed, phenols.Have clearing heat and detoxicating, dampness removing, astringing to arrest bleeding effect.Clinically be mainly used to enteritis, dysentery, haematemesis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, hematuria, uterine bleeding, carbuncle furuncle sore, skin eczema.(7) cactus: bitter, cool in nature.Be rich in compositions such as alkaloid, flavonoids such as flavonols, sterols such as sitosterol and grease, protein, polysaccharide, trace element.Have clearing heat and detoxicating, eliminating stasis to subdue swelling, benefiting stomach and stopping pain, antibechic effect, be used for stomach, duodenal ulcer, acute dysentery, cough, mastitis, carbuncle furuncle poison, snake bite, burn and scald etc.
The present invention is used to prevent the preparation flow of the Chinese herbal feed additive of livestock and poultry diarrhea to be: and the water of the picking → clean of crude drug → cut medicine → first carries → and secondary water carries → collecting decoction → concentrate → absorption → oven dry → packing.
The major control condition is as follows:
Operating ambient temperature: 18-30 ℃, relative humidity 30-70%, the clean rank of production area is general production area;
Water is proposed control: water drawings water quality standard is a drinking water, and water is carried 10 times (W/W) that amount of water is an inventory first, and material adds the back and soaked 2 hours, and extraction time is 2 hours, and extracting the control temperature is 100 ℃, and mixing speed is 24 rev/mins; The amount of water that secondary water is carried is 5 times (W/W) of inventory, and extraction time is 1 hour, and extracting the control temperature is 100 ℃, and mixing speed is 24 rev/mins;
Concentrate control: under stirring, adopt the Steam Heating mode to concentrate, 40 rev/mins of speeds of agitator, mixing time 15 minutes, the heating-up temperature that is heated soup in the control concentration heater is 80～100 ℃, vacuum is-0.4～0.6 MPa, and soup is concentrated into and the crude drug identical weight.
Absorption control: add adsorbent silica, the amount of silica is 85% of a crude drug weight, and adsorption time is 1 hour, and temperature is 50～80 ℃.
Oven dry control: bake out temperature is 120 ℃, and the time is 1.5 hours, and mixing speed is 24 rev/mins.
Be used to prevent and treat the concrete steps of the compound Chinese herb feed addictive preparation process of livestock and poultry diarrhea:
1, picking the crude drug lay in picking on the platform of crude drug sorted out the impurity in the crude drug one by one.
2, clean and will put in the service sink through the crude drug of picking, with the drinking water washing, and the medicinal material after will washing puts into second service sink and embathes, and cleans in the rearmounted container to drain away the water.
3, cut medicine and according to routine the tubers crude drug is put and be cut into sheet in the medicine cutter, and will need the crude drug of coarse crushing to put coarse crushing in the boulder crusher, put into container, it is stand-by to send into next procedure.
4, water is carried
4.1, prepare burden operating ambient temperature: 18-30 ℃ relative humidity 30-70% according to each component of weight proportion weighing of crude drug;
4.2 water is carried the drinking water that is incorporated as inventory 10 times (W/W) in extractor first, starts stirring motor, mixing speed is 24 rev/mins;
Carry in the jar 4.3 required various Chinese herbal medicines are joined water, material soaked 2 hours;
4.4 adopt extractions that heat up of Steam Heating mode, to open steam valve and heat up, control extraction temperature is 100 ℃, keeps after 2 hours first water to propose end, and the soup that has extracted is delivered to storage tank after filtering;
4.5 in extractor, add the drinking water of inventory 5 times (W/W) when secondary water is carried, repeat 4.3,4.4 steps, mixing speed is 24 rev/mins, wait to be warming up to 100 ℃ of materials and boil extraction time when reaching 1 hour, the steam off inlet valve extracts good soup with secondary water and is transported to storage tank after filtering;
Carry the extracted twice liquid of carrying with secondary water 4.6 merge first water.
5, the merging soup that concentrates after water carried is transported to concentration heater through head tank, under stirring, adopt the Steam Heating mode to concentrate, 40 rev/mins of speeds of agitator, mixing time 15 minutes, opening steam valve heats up concentrated, the heating-up temperature that is heated soup in the control concentration heater is 80～100 ℃, and vacuum is-0.4～0.6 MPa, until being concentrated into and the crude drug identical weight.
6, absorption is incorporated as the adsorbent silica of crude drug weight 85% in concentration heater, and adsorption time is 1 hour, and temperature is 50～80 ℃.
7, oven dry will change baking oven over to and dry through the mixture of absorption gained, and temperature is 120 ℃, and the time is 1.5 hours, and mixing speed is 24 rev/mins.
8, packing with product according to the rules loading amount pack in the packaging bag, and stick Product labelling.
Prevent the technical indicator of Chinese herbal feed additive finished product of livestock and poultry diarrhea as follows through above method being used to of making:
| Sequence number | Project | Index |
| 1 | Proterties | Taupe or pale powder |
| 2 | Active ingredient (general flavone) weight content | ≥6.6‰ |
| 3 | The moisture weight content | ≤10％ |
Advantage of the present invention prevents the Chinese herbal feed additive of livestock and poultry diarrhea to have the effect that the prevention livestock and poultry diarrhea has growth promotion concurrently, strengthens immunity with regard to being, since by to the extraction of each crude drug in the prescription, concentrate, absorption makes, Chinese herbal feed additive has the active constituent content height, the consumption traceization, be easy to use and have natural sex, noresidue, advantage such as have no drug resistance; The dosage form design of product of the present invention is become pulvis, not only be convenient to store, transport, and be convenient to add use, and can keep the good stability of product.
Chinese herbal feed additive of the present invention all has good restraining and killing action to encountered pathogenic such as Escherichia coli, salmonella, rotavirus, epidemic diarrhea virus and the TGE etc. that cause livestock and poultry diarrhea, by repairing intestinal mucosa, help the intestinal microecology flora to rebuild; The present invention simultaneously is remarkable to the trophism diarrhea effect that causes because of protein content in the feed is too high.Chinese herbal feed additive of the present invention, warp is in Jiangsu over 2 years, Guangdong, Shandong, Henan, Hebei, Fujian, the 182 tame pig farms in a plurality of provinces such as Anhui and 3425 pigs in 220 tame chicken farms, 450000 chickens are on probation, add by spice, in the feed per ton according to newborn piglet: 300-400g, growth pig: 200g, in big pig: 200g, young fowl: 300g, in big fowl 100-200g, the consumption of egg fowl: 50-150g makes an addition in the livestock and poultry diet for a long time, the result shows that Chinese herbal feed additive of the present invention is the prevention pig, chicken diarrhea improves the speed of growth, aspect effects such as enhancing immunity of livestock are remarkable.
The specific embodiment
Below be embodiments of the invention, the actual use of the present invention is not limited to embodiment.
Embodiment 1, Chinese herbal feed additive of prevention livestock and poultry diarrhea and preparation method thereof
Adopt the Chinese herbal feed additive preparation method of prevention livestock and poultry diarrhea of the present invention to prepare Chinese herbal feed additive, crude drug is made up of fortune paulownia flower, purslane, polygonum flaccidum, geranium wilfordii, garden burnet, acalypha copperleaf and cactus, and the weight proportion of crude drug is: fortune paulownia flower 32kg, purslane 25kg, polygonum flaccidum 23kg, geranium wilfordii 20kg, garden burnet 20kg, acalypha copperleaf 15kg and cactus 10kg; Said herbal medicine through pick, clean, cut medicine, water is carried first, secondary water is carried, collecting decoction, concentrate, Chinese herbal feed additive that absorption and oven dry make the prevention livestock and poultry diarrhea; Adsorbent is selected silica for use in preparation process, and silica is 85% of crude drug weight as one of the composition of Chinese herbal feed additive addition.
Main production equipments:
| Sequence number | Device name | Type and spec | Quantity |
| 1 | Reciprocating type medicine cutter | WQY240 | 1 |
| 2 | Boulder crusher | MZ200 | 1 |
| 3 | Dynamic extraction pot | 3m 3 | 1 |
| 4 | Basin | 3m 3 | 1 |
| 5 | The magnetically-actuated reflux pump | 40CQ-2 | 1 |
| 6 | The scraper-type vacuum concentrator | 1m 3 | 1 |
| 7 | Head tank | 1m 3 | 1 |
| 8 | Tube still heater | 200m 2 | 1 cover |
| 9 | Preparing tank | 1000L | 1 |
| 10 | CT-C-II baking oven | 200m2 | 1 |
| 11 | Electronic balance | JJ2000 | 1 |
| 12 | Labelling machine | LT | 1 |
| 13 | Electronic platform scale | TCS-30 | 1 |
The major control condition is as follows:
Operating ambient temperature: 18-30 ℃, relative humidity 30-70%, the clean rank of production area is general production area;
Water is proposed control: water drawings water quality standard is a drinking water, and water is carried 10 times (W/W) that amount of water is an inventory first, and material adds the back and soaked 2 hours, and extraction time is 2 hours, and extracting the control temperature is 100 ℃, and mixing speed is 24 rev/mins; The amount of water that secondary water is carried is 5 times (W/W) of inventory, and extraction time is 1 hour, and extracting the control temperature is 100 ℃, and mixing speed is 24 rev/mins;
Concentrate control: under stirring, adopt the Steam Heating mode to concentrate, 40 rev/mins of speeds of agitator, mixing time 15 minutes, the heating-up temperature that is heated soup in the control concentration heater is 80～100 ℃, vacuum is-0.4～0.6 MPa, and soup is concentrated into and the crude drug identical weight.
Absorption control: add adsorbent silica, the amount of silica is 85% of a crude drug weight, and adsorption time is 1 hour, and temperature is 50～80 ℃.
Oven dry control: bake out temperature is 120 ℃, and the time is 1.5 hours, and mixing speed is 24 rev/mins.
The crude drug of above proportioning is operated according to following operation:
1, picking the crude drug lay in picking on the platform of crude drug sorted out the impurity in the crude drug one by one.
2, clean and will put in the service sink through the crude drug of picking, with the drinking water washing, and the medicinal material after will washing puts into second service sink and embathes, and cleans in the rearmounted container to drain away the water.
3, cut medicine and according to routine the tubers crude drug is put in the reciprocating type medicine cutter and be cut into sheet, and will need the crude drug of coarse crushing to put coarse crushing in the boulder crusher, put into container, it is stand-by to send into next procedure.
4, water is carried
4.1, prepare burden operating ambient temperature: 18-30 ℃ relative humidity 30-70% according to each component of weight proportion weighing of crude drug;
4.2 the drinking water that is 1450kg is carried and be incorporated as inventory 10 times (W/W) in dynamic extraction pot to water first, starts stirring motor, mixing speed is 24 rev/mins;
4.3 required various Chinese herbal medicines are joined in the dynamic extraction pot, and material soaked 2 hours;
4.4 adopt extractions that heat up of Steam Heating mode, to open steam valve and heat up, control extraction temperature is 100 ℃, keeps after 2 hours first water to propose end, and the soup that has extracted is delivered to basin after filtering;
4.5 in dynamic extraction pot, add the drinking water of 5 times of (W/W) 725kg of inventory when secondary water is carried, repeat 4.3,4.4 steps, mixing speed is 24 rev/mins, wait to be warming up to 100 ℃ of materials and boil extraction time when reaching 1 hour, the steam off inlet valve extracts good soup with secondary water and is transported to basin after filtering;
Carry the extracted twice liquid of carrying with secondary water 4.6 merge first water.
5, the merging soup that concentrates after water carried is transported to the scraper-type vacuum concentrator through head tank, under stirring, adopt the Steam Heating mode to concentrate, 40 rev/mins of speeds of agitator, mixing time 15 minutes, opening steam valve heats up concentrated, the heating-up temperature that is heated soup in the control scraper-type vacuum concentrator is 80～100 ℃, and vacuum is-0.4～0.6 MPa, until being concentrated into and the crude drug identical weight.
6, absorption is incorporated as the adsorbent silica that crude drug weight 85% is 123.25kg in the scraper-type vacuum concentrator, and adsorption time is 1 hour, and temperature is 50～80 ℃.
7, oven dry will change baking oven over to and dry through the mixture of absorption gained, and temperature is 120 ℃, and the time is 1.5 hours, and mixing speed is 24 rev/mins.
8, packing with product according to the rules loading amount pack in the packaging bag, and stick Product labelling.
Use above method and make the Chinese herbal feed additive 145kg that comprises the adsorbent silica composition.
Being used to of making prevents the technical indicator of Chinese herbal feed additive finished product of livestock and poultry diarrhea as follows:
| Sequence number | Project | Index |
| 1 | Proterties | The taupe powder |
| 2 | Active ingredient (general flavone) weight content | 7.0‰ |
| 3 | The moisture weight content | 5.8％ |
The Chinese herbal feed additive that prevents livestock and poultry diarrhea is applied to 35 raises on a household basis the pig farm, use amounting to 176 weanling pigs, addition according to the 300g/kg body weight uses, feeding experiment through 1 month, test group pig diarrhoea incidence only only is 1.6%, a pig phenomena of mortality do not appear in the whole test phase, and the grice diarrhoea incidence of control group is up to 21.5%, and pig is only because of excessively dead 2 of diarrheal dehydration in the whole test phase; The weightening finish only of test group pig is significantly higher than control group (p＜0.05), and test group pig feedstuff-meat ratio only is 0.32:1, and the feedstuff-meat ratio of control group is 0.36:1.As seen, the Chinese herbal feed additive of this prevention livestock and poultry diarrhea effect aspect prevention diarrhoea, growth promotion, enhancing immunity is more obvious.
Embodiment 2, Chinese herbal feed additive of prevention livestock and poultry diarrhea and preparation method thereof
Adopt the present invention to prevent the Chinese herbal feed additive preparation method of livestock and poultry diarrhea to prepare Chinese herbal feed additive, crude drug is made up of fortune paulownia flower, purslane, polygonum flaccidum, geranium wilfordii, garden burnet, acalypha copperleaf and cactus, and the weight proportion of crude drug is fortune paulownia flower 29kg, purslane 22kg, polygonum flaccidum 20kg, geranium wilfordii 17kg, garden burnet 17kg, acalypha copperleaf 13kg and cactus 8kg.Said herbal medicine through pick, clean, cut medicine, water is carried first, secondary water is carried, collecting decoction, concentrate, Chinese herbal feed additive that absorption and oven dry make the prevention livestock and poultry diarrhea; Adsorbent is selected silica for use in preparation process, and silica is 85% of crude drug weight as one of the composition of Chinese herbal feed additive addition.
Main production equipments, major control condition and production process make the Chinese herbal feed additive of 126kg altogether with embodiment 1.
The technical indicator of the finished product of the Chinese herbal feed additive of the prevention livestock and poultry diarrhea that makes sees the following form:
| Sequence number | Project | Index |
| 1 | Proterties | The taupe powder |
| 2 | Active ingredient (general flavone) weight content | 7.2‰ |
| 3 | The moisture weight content | 5.5％ |
The Chinese herbal feed additive of the prevention livestock and poultry diarrhea that this embodiment is made is applied to AA fryer feeding experiment, in the early stage material according to the addition that adds 300g in the daily ration per ton, use according to the addition that adds 150g in the daily ration per ton in the later stage material, the result shows, the average diarrhoea number of times of test group has reduced by 32% than control group in the pre-stage test, the average diarrhoea number of times of test group has reduced by 55% than control group in the later stage test, has reached the extremely significantly effect of (p＜0.01) of difference; The whose body weight of test group chicken is compared with antibiotic interpolation control group and has been improved 3.56 percentage points, significant difference (p＜0.05), and expect that anharmonic ratio has reduced by 0.03, improved the price of deed; Moreover the death rate of full phase of test group is 0.68%, and the death rate of control group has reached 3.71%, is higher than the interpolation group of product of the present invention far away.Thereby the effect of the anti-diarrhoea of the Chinese herbal feed additive of this prevention livestock and poultry diarrhea, growth promotion, enhancing immunity also clearly.
Embodiment 3, Chinese herbal feed additive of prevention livestock and poultry diarrhea and preparation method thereof
Adopt the present invention to prevent the Chinese herbal feed additive preparation method of livestock and poultry diarrhea to prepare Chinese herbal feed additive, crude drug is made up of fortune paulownia flower, purslane, polygonum flaccidum, geranium wilfordii, garden burnet, acalypha copperleaf and cactus, and the weight proportion of crude drug is fortune paulownia flower 35kg, purslane 28kg, polygonum flaccidum 26kg, geranium wilfordii 23kg, garden burnet 23kg, acalypha copperleaf 17kg and cactus 12kg; Said herbal medicine through pick, clean, cut medicine, water is carried first, secondary water is carried, collecting decoction, concentrate, Chinese herbal feed additive that absorption and oven dry make the prevention livestock and poultry diarrhea; Adsorbent is selected silica for use in preparation process, and silica is 85% of crude drug weight as one of the composition of Chinese herbal feed additive addition.
Main production equipments, major control condition and production process are with embodiment 1.Make the Chinese herbal feed additive of 164kg altogether.
The finished product of the Chinese herbal feed additive of the prevention livestock and poultry diarrhea of preparation reaches following technical indicator:
| Sequence number | Project | Index |
| 1 | Proterties | The taupe powder |
| 2 | Active ingredient (general flavone) weight content | 6.8‰ |
| 3 | The moisture weight content | 6.0％ |
The Chinese herbal feed additive finished product of prevention livestock and poultry diarrhea is carried out the feeding experiment of the blue brown laying hen in laying period sea, use according to the addition that adds 150g in the material per ton, the whole test phase is 45 days, and the result shows: the diarrhoea incidence of control group laying hen is 26.5%, and test group only is 4.6%; The laying rate of test group laying hen improves 2.85 percentage points than control group, and average unit egg size has also increased 2.15g than control group; Simultaneously the death rate of test group laying hen only is 0.12%, and control group up to 0.68%.As seen, the effect of the anti-diarrhoea of the Chinese herbal feed additive of this prevention livestock and poultry diarrhea, growth promotion, enhancing immunity also clearly.
Claims (10)
1, a kind of Chinese herbal feed additive that prevents livestock and poultry diarrhea, it is characterized in that by fortune paulownia flower, purslane, polygonum flaccidum, geranium wilfordii, garden burnet, acalypha copperleaf and cactus are prepared from, the weight proportion scope of crude drug is: fortune paulownia flower 29-35 part, purslane 22-28 part, polygonum flaccidum 20-26 part, geranium wilfordii 17-23 part, garden burnet 17-23 part, acalypha copperleaf 13-17 part and cactus 8-12 part, said herbal medicine is through picking, clean, cut medicine, water is carried first, secondary water is carried, collecting decoction, concentrate, absorption and oven dry make the Chinese herbal feed additive of prevention livestock and poultry diarrhea, adsorbent is selected silica for use in preparation process, and silica is 85% of crude drug weight as one of the composition of Chinese herbal feed additive addition.
2, the Chinese herbal feed additive of prevention livestock and poultry diarrhea according to claim 1 is characterized in that the crude drug weight proportion of Chinese herbal feed additive is: 10 parts in 32 parts of fortune paulownia flowers, 25 parts of purslanes, 23 parts of polygonum flaccidums, 20 parts of geranium wilfordiis, 20 parts of garden burnets, 15 parts of acalypha copperleafs and cactus.
3, the Chinese herbal feed additive of prevention livestock and poultry diarrhea according to claim 1, the weight proportion that it is characterized in that crude drug are fortune paulownia flower 32kg, purslane 25kg, polygonum flaccidum 23kg, geranium wilfordii 20kg, garden burnet 20kg, acalypha copperleaf 15kg and cactus 10kg.
4, the Chinese herbal feed additive of prevention livestock and poultry diarrhea according to claim 1, the weight proportion that it is characterized in that crude drug are fortune paulownia flower 29kg, purslane 22kg, polygonum flaccidum 20kg, geranium wilfordii 17kg, garden burnet 17kg, acalypha copperleaf 13kg and cactus 8kg.
5, the Chinese herbal feed additive of prevention livestock and poultry diarrhea according to claim 1, the weight proportion that it is characterized in that crude drug are fortune paulownia flower 35kg, purslane 28kg, polygonum flaccidum 26kg, geranium wilfordii 23kg, garden burnet 23kg, acalypha copperleaf 17kg and cactus 12kg.
6, the Chinese herbal feed additive of prevention livestock and poultry diarrhea according to claim 1 is characterized in that the Chinese herbal feed additive finished product is taupe or pale powder, active ingredient general flavone weight content 〉=6.6 ‰, moisture weight content≤10%.
7, the Chinese herbal feed additive of prevention livestock and poultry diarrhea according to claim 3 is characterized in that Chinese herbal feed additive finished product active ingredient general flavone weight content is 7.0 ‰, moisture weight content 5.8%.
8, the Chinese herbal feed additive of prevention livestock and poultry diarrhea according to claim 4 is characterized in that Chinese herbal feed additive finished product active ingredient general flavone weight content is 7.2 ‰, moisture weight content 5.5%.
9, the Chinese herbal feed additive of prevention livestock and poultry diarrhea according to claim 5 is characterized in that Chinese herbal feed additive finished product active ingredient general flavone weight content is 6.8 ‰, moisture weight content 6.0%.
10, a kind of preparation method who prevents the Chinese herbal feed additive of livestock and poultry diarrhea is characterized in that the preparation flow of Chinese herbal feed additive is: and the water of the picking → clean of crude drug → cut medicine → first carries → and secondary water carries → collecting decoction → concentrate → absorption → oven dry → packing; Major control condition: operating ambient temperature: 18-30 ℃, relative humidity 30-70%, the clean rank of production area is general production area; Water is proposed control: water drawings water quality standard is a drinking water, and to carry amount of water be 10 times of inventory weight to water first, and material adds the back and soaked 2 hours, and extraction time is 2 hours, and extracting the control temperature is 100 ℃, and mixing speed is 24 rev/mins; The amount of water that secondary water is carried is 5 times of inventory weight, and extraction time is 1 hour, and extracting the control temperature is 100 ℃, and mixing speed is 24 rev/mins; Concentrate control: under stirring, adopt the Steam Heating mode to concentrate, 40 rev/mins of speeds of agitator, mixing time 15 minutes, the heating-up temperature that is heated soup in the control concentration heater is 80～100 ℃, vacuum is-0.4～0.6 MPa, and soup is concentrated into and the crude drug identical weight; Absorption control: add adsorbent silica, the amount of silica is 85% of a crude drug weight, and adsorption time is 1 hour, and temperature is 50～80 ℃; Oven dry control: bake out temperature is 120 ℃, and the time is 1.5 hours, and mixing speed is 24 rev/mins.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101551970A CN101385505B (en) | 2008-10-24 | 2008-10-24 | Chinese herbal medicine feed additive for preventing livestock and poultry diarrhea and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101551970A CN101385505B (en) | 2008-10-24 | 2008-10-24 | Chinese herbal medicine feed additive for preventing livestock and poultry diarrhea and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101385505A true CN101385505A (en) | 2009-03-18 |
| CN101385505B CN101385505B (en) | 2010-12-29 |
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| CN102488083A (en) * | 2011-12-01 | 2012-06-13 | 镇江天和生物技术有限公司 | Paulownia leaf extract feed additive |
| CN102488082A (en) * | 2011-12-01 | 2012-06-13 | 镇江天和生物技术有限公司 | Paulownia flower extractive feed additives |
| CN101695339B (en) * | 2009-10-29 | 2012-07-04 | 镇江天和生物技术有限公司 | Pure Chinese medicinal immunopotentiator special for animal |
| CN102038079B (en) * | 2009-10-15 | 2013-01-16 | 上海朝翔生物技术有限公司 | Paulownia extract feed additive and preparation method thereof |
| CN104171313A (en) * | 2014-07-21 | 2014-12-03 | 镇江天和生物技术有限公司 | Feed additive specially used for pigs in nursery period and preparation method thereof |
| CN105250727A (en) * | 2015-11-16 | 2016-01-20 | 汪鲲 | Traditional Chinese medicine composition for prevention and treatment of livestock diarrhea and preparation method of traditional Chinese medicine composition |
| CN109349425A (en) * | 2018-10-27 | 2019-02-19 | 江苏波杜农牧股份有限公司 | A kind of Chinese herbal feed additive and preparation method thereof |
| CN111587953A (en) * | 2020-06-04 | 2020-08-28 | 南京农业大学 | Traditional Chinese medicine compound feed additive for replacing antibiotics and preparation method and application thereof |
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| CN1718078A (en) * | 2004-07-07 | 2006-01-11 | 王彦明 | Additives for fodder in husbandry, and its application |
| CN101066313B (en) * | 2007-04-23 | 2011-04-20 | 张丛娥 | Chinese medicine preparation for antagonizing bacteria and viruses of pig and improving pork quality, and its preparation process |
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| CN101229196B (en) * | 2008-01-14 | 2011-04-20 | 河北师范大学 | Microecologic agent preventing grice diarrhoea and preparing method thereof |
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- 2008-10-24 CN CN2008101551970A patent/CN101385505B/en not_active Expired - Fee Related
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| CN102038079B (en) * | 2009-10-15 | 2013-01-16 | 上海朝翔生物技术有限公司 | Paulownia extract feed additive and preparation method thereof |
| CN101695339B (en) * | 2009-10-29 | 2012-07-04 | 镇江天和生物技术有限公司 | Pure Chinese medicinal immunopotentiator special for animal |
| CN102488083A (en) * | 2011-12-01 | 2012-06-13 | 镇江天和生物技术有限公司 | Paulownia leaf extract feed additive |
| CN102488082A (en) * | 2011-12-01 | 2012-06-13 | 镇江天和生物技术有限公司 | Paulownia flower extractive feed additives |
| CN104171313A (en) * | 2014-07-21 | 2014-12-03 | 镇江天和生物技术有限公司 | Feed additive specially used for pigs in nursery period and preparation method thereof |
| CN105250727A (en) * | 2015-11-16 | 2016-01-20 | 汪鲲 | Traditional Chinese medicine composition for prevention and treatment of livestock diarrhea and preparation method of traditional Chinese medicine composition |
| CN109349425A (en) * | 2018-10-27 | 2019-02-19 | 江苏波杜农牧股份有限公司 | A kind of Chinese herbal feed additive and preparation method thereof |
| CN111587953A (en) * | 2020-06-04 | 2020-08-28 | 南京农业大学 | Traditional Chinese medicine compound feed additive for replacing antibiotics and preparation method and application thereof |
| CN111587953B (en) * | 2020-06-04 | 2022-04-22 | 南京农业大学 | Traditional Chinese medicine compound feed additive for replacing antibiotics and preparation method and application thereof |
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