CN101322760A - Compound Chinese herbal medicine formulation for treating causative pathogen skin ulcerative syndrome of Apostichopus japonicus - Google Patents
Compound Chinese herbal medicine formulation for treating causative pathogen skin ulcerative syndrome of Apostichopus japonicus Download PDFInfo
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- CN101322760A CN101322760A CNA2008100126413A CN200810012641A CN101322760A CN 101322760 A CN101322760 A CN 101322760A CN A2008100126413 A CNA2008100126413 A CN A2008100126413A CN 200810012641 A CN200810012641 A CN 200810012641A CN 101322760 A CN101322760 A CN 101322760A
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Abstract
The invention discloses a compound Chinese herbal preparation for treating bacterial ulcerate disease of apostichopus japonicus selenka; the components of the Chinese herbal preparation are as follows by weight ratio: 80-90% of dark plum and 10-20% of Chinese gall. After the decocting of the components by water, the preparation obtained is used for medicated bath of apostichopus japonicus selenka or sprinkled in a whole pool and has reasonable composition formula. The compound Chinese herbal preparation has the following advantages that the raw materials are prepared based on the formula for Chinese medicinal herbs, thus the drug efficacy is strengthened; meanwhile, the preparation has no toxicity for the apostichopus japonicus selenka and no influence on the normal life of the apostichopus japonicus selenka, has quite obvious effect on killing pathogens in apostichopus japonicusand selenka and can repair ulcerate tissues thoroughly; the compound Chinese herbal preparation is degradable under the natural conditions, and has no toxic and side effect and no residue in the apostichopus japonicus selenka; the compound Chinese herbal preparation has less recruitment, convenient use, simple composition, stable raw material source, cheap price and simple production process.
Description
Technical field:
The present invention relates to a kind of Chinese medicine formula, especially a kind of Radix Morinae Bulleyanae artificial cultivation that can be applicable to, is repaired the fester Chinese medicine formula of tissue of Radix Morinae Bulleyanae at the treatment causative pathogen skin ulcerative syndrome of Apostichopus japonicus.
Background technology:
Radix Morinae Bulleyanae is one of important economic breed variety of northern China coastal area.But along with culture overrun development and running lack of standardization and the disease problem that causes is given prominence to day by day, the multiple manifest symptom and the extensive phenomena of mortality have appearred, caused heavy economic loss for vast apostichopus japonicus culture dealer, wherein " changing the skin disease " is exactly the most popular at present and the most serious disease of influence.Their early stage is small size to occur at the Radix Morinae Bulleyanae body wall to fester " to change the skin disease ", and rotten position increases gradually afterwards, so that finally be dissolved into the nasal mucus shape.Result of study proof Radix Morinae Bulleyanae so far " changes the skin disease " and is mainly due to the bacterial infection, and pathogen mainly contains Vibrio splindidus, vibrio alginolyticus, Pseudoalteromonas, pseudomonas and Shiva Salmonella etc.At present, antibiotic medicine is mainly adopted in control at this disease, but antibiotic medicine can only play the effect of killing pathogenic bacteria, can not help Radix Morinae Bulleyanae to repair the tissue that has festered, and a large amount of antibiotic uses certainly will cause the appearance of Resistant strain, and drug residue that is produced and the diffusion problem in environment have also had a strong impact on food safety and environment public health security.Chinese herbal medicine is a kind of green non-pollution means of production, research and development as the Radix Morinae Bulleyanae feed additive have obtained certain achievement and within the specific limits the premunition that improves Radix Morinae Bulleyanae have been had effect preferably, but up to now, also there is not to have at causative pathogen skin ulcerative syndrome of Apostichopus japonicus specially the shaping Chinese herbal and crude drugs preparations of stable therapeutic effect.
Summary of the invention:
The present invention does not have the technical problem of the Chinese herbal and crude drugs preparations of special for treating causative pathogen skin ulcerative syndrome of Apostichopus japonicus in order to solve existing in prior technology, provide a kind of to the treatment causative pathogen skin ulcerative syndrome of Apostichopus japonicus, repair that Radix Morinae Bulleyanae festers that tissue has positive effect and Radix Morinae Bulleyanae and breeding environment do not had the Chinese herbal and crude drugs preparations of harm.
Technical solution of the present invention is: a kind of Chinese medicine formula for the treatment of causative pathogen skin ulcerative syndrome of Apostichopus japonicus is characterized in that each component and percentage by weight are:
Fructus Mume 80～90%
Galla Chinensis 10～20%
The optimum weight percentage ratio of each component is:
Fructus Mume 85%
Galla Chinensis 15%
The present invention a kind ofly is specifically designed to the treatment causative pathogen skin ulcerative syndrome of Apostichopus japonicus, repairs the fester Chinese herbal and crude drugs preparations of tissue of Radix Morinae Bulleyanae, contains two kinds of Chinese medicine ingredients of Fructus Mume and Galla Chinensis, being used to prickle was joined after decocting boiled dipping or full pool spilling head.The component collocation rationally has following advantage: (1) raw material is according to the formulation principle of Chinese herbal medicine, when strengthening drug effect, Radix Morinae Bulleyanae there is not toxicity, can not influence the orthobiosis of Radix Morinae Bulleyanae, remarkable to the intravital pathogen killing effect of Radix Morinae Bulleyanae, and can thoroughly repair the tissue that festers; (2) degradable under field conditions (factors) has no side effect noresidue in the Radix Morinae Bulleyanae body; (3) addition is little, and is easy to use; (4) form simply, raw materials used steady sources, cheap, production technology is simple.
Embodiment 1:
Get Fructus Mume 80 gram, Galla Chinensis 20 grams, the decocting cooking method makes medicinal liquid routinely, and (body is long by 10～11cm), and its curative effect sees Table 1 with 10 naturalization prickles ginsengs of the dose dipping Dalian Bay apostichopus japonicus culture field of 50mg/L.
Embodiment 2:
Get Fructus Mume 90 gram, Galla Chinensis 10 grams, the decocting cooking method makes medicinal liquid routinely, and (body is long by 8～9cm), and its curative effect sees Table 1 with 10 naturalization prickles ginsengs of the apostichopus japonicus culture field, dose dipping Wafangdian of 50mg/L.
Embodiment 3:
Get Fructus Mume 80 gram, Galla Chinensis 20 grams, the decocting cooking method makes medicinal liquid routinely, and (body grows 9～10cm), and its curative effect sees Table 1 with 10 of the Radix Morinae Bulleyanaes of causing of the dose dipping artificial challenge Vibrio splindidus skin of 50mg/L.
Embodiment 4:
Get Fructus Mume 85 gram, Galla Chinensis 15 grams, the decocting cooking method makes medicinal liquid routinely, and (body grows 7～8cm), and its curative effect sees Table 1 with 10 of the Radix Morinae Bulleyanaes of causing of the dose dipping artificial challenge Shiva Salmonella skin of 50mg/L.
Embodiment 5:
Get Fructus Mume 90 gram, Galla Chinensis 10 grams, the decocting cooking method makes medicinal liquid routinely, and (body grows 8～9cm), and its curative effect sees Table 1 with 10 of the Radix Morinae Bulleyanaes of causing of the dose dipping artificial challenge Pseudoalteromonas skin of 50mg/L.
Table 1
| Embodiment | Sick parameter amount (head) | Recovery from illness quantity (head) | Radix Morinae Bulleyanae is cured the back performance |
| 1 | 10 | 7 | Change skin and fester that disappearance, parapodum grow again, health is unfolded |
| 2 | 10 | 8 | Change skin and fester that disappearance, parapodum grow again, health is unfolded |
| 3 | 10 | 8 | Changing fester disappearance, health of skin unfolds |
| 4 | 10 | 9 | Changing fester disappearance, health of skin unfolds |
| 5 | 10 | 8 | Changing fester disappearance, health of skin unfolds |
Claims (2)
1. Chinese medicine formula for the treatment of causative pathogen skin ulcerative syndrome of Apostichopus japonicus is characterized in that each component and percentage by weight are:
Fructus Mume 80～90%
Galla Chinensis 10～20%.
2. the Chinese medicine formula of treatment causative pathogen skin ulcerative syndrome of Apostichopus japonicus according to claim 1 is characterized in that each weight percentages of components is:
Fructus Mume 85%
Galla Chinensis 15%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100126413A CN101322760B (en) | 2008-08-06 | 2008-08-06 | Compound Chinese herbal medicine formulation for treating causative pathogen skin ulcerative syndrome of Apostichopus japonicus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100126413A CN101322760B (en) | 2008-08-06 | 2008-08-06 | Compound Chinese herbal medicine formulation for treating causative pathogen skin ulcerative syndrome of Apostichopus japonicus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101322760A true CN101322760A (en) | 2008-12-17 |
| CN101322760B CN101322760B (en) | 2012-07-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2008100126413A Expired - Fee Related CN101322760B (en) | 2008-08-06 | 2008-08-06 | Compound Chinese herbal medicine formulation for treating causative pathogen skin ulcerative syndrome of Apostichopus japonicus |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102370839A (en) * | 2011-11-30 | 2012-03-14 | 刘正殿 | Medicament for treating sea cucumber disease |
| CN103289913A (en) * | 2013-01-27 | 2013-09-11 | 大连海宝渔业有限公司 | Apostichopus japonicus Pseudomonas elyacovii HS1 strain and its use |
| CN104872416A (en) * | 2015-05-05 | 2015-09-02 | 中国林业科学研究院林产化学工业研究所 | Application of galla chinensis extract |
| CN105030954A (en) * | 2015-07-24 | 2015-11-11 | 成都乾坤动物药业有限公司 | Composition and preparation for treating piglet scours, preparing method and application of composition |
| CN105560548A (en) * | 2016-01-14 | 2016-05-11 | 大连海洋大学 | Plant source compound preparation special for apostichopus japonicus reversed pond medicated bath |
| CN107582662A (en) * | 2017-08-29 | 2018-01-16 | 大连海洋大学 | The quick Chinese herbal formula for repairing apostichopus japonicus body-wall skin tissue |
-
2008
- 2008-08-06 CN CN2008100126413A patent/CN101322760B/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102370839A (en) * | 2011-11-30 | 2012-03-14 | 刘正殿 | Medicament for treating sea cucumber disease |
| CN103289913A (en) * | 2013-01-27 | 2013-09-11 | 大连海宝渔业有限公司 | Apostichopus japonicus Pseudomonas elyacovii HS1 strain and its use |
| CN103289913B (en) * | 2013-01-27 | 2015-03-11 | 大连海宝渔业有限公司 | Apostichopus japonicus Pseudomonas elyacovii HS1 strain and its use |
| CN104872416A (en) * | 2015-05-05 | 2015-09-02 | 中国林业科学研究院林产化学工业研究所 | Application of galla chinensis extract |
| CN105030954A (en) * | 2015-07-24 | 2015-11-11 | 成都乾坤动物药业有限公司 | Composition and preparation for treating piglet scours, preparing method and application of composition |
| CN105030954B (en) * | 2015-07-24 | 2018-05-29 | 成都乾坤动物药业股份有限公司 | A kind of composition, preparation, preparation method and applications for treating grice diarrhoea |
| CN105560548A (en) * | 2016-01-14 | 2016-05-11 | 大连海洋大学 | Plant source compound preparation special for apostichopus japonicus reversed pond medicated bath |
| CN107582662A (en) * | 2017-08-29 | 2018-01-16 | 大连海洋大学 | The quick Chinese herbal formula for repairing apostichopus japonicus body-wall skin tissue |
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|---|---|
| CN101322760B (en) | 2012-07-04 |
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Granted publication date: 20120704 Termination date: 20120806 |