CN101972314A - Drug for controlling fish gas disease and preparation method thereof - Google Patents
Drug for controlling fish gas disease and preparation method thereof Download PDFInfo
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- CN101972314A CN101972314A CN2010102569786A CN201010256978A CN101972314A CN 101972314 A CN101972314 A CN 101972314A CN 2010102569786 A CN2010102569786 A CN 2010102569786A CN 201010256978 A CN201010256978 A CN 201010256978A CN 101972314 A CN101972314 A CN 101972314A
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Abstract
The invention relates to a drug for controlling a fish gas disease which is characterized by being prepared from the following raw materials in parts by weight: 30-40 parts of gall nut, 30-40 parts of Chinese teasel root and 20-40 parts of salt. A preparation method comprises the steps of: weighting 30-40 parts of gall nut and 30-40 parts of Chinese teasel root in parts by weight; adding water in the proportion of 1:10-12 relative to the total weight of the raw materials, soaking for 20-30min, decocting twice according to a conventional method; decocting with slow fire for 30-40min after first boiling, filtering; adding 6-8 times of water in filter residue for boiling and then decocting with slow fire for 20-30min, filtering; merging two times of filtrate, then filtering, condensing the filtrate at a temperature of 40-50 DEG C until the relative density is 1.05-1.20; finally, cooling concentrate to room temperature; then weight 20-40 parts of salt, slowly adding into concentrate for dissolving the salt, and packaging into 5000ml/bottle. The invention has the advantages of reasonable formula, simple preparation and environment protection without pollution, effectively controls the fish gas disease through synergistic effect of the raw materials, promotes the fish growth, improves the survival rate, and remarkably enhances the economic benefit.
Description
Technical field
The present invention relates to a kind of medicine of preventing and treating fish disease and preparation method thereof, particularly a kind of medicine of preventing and treating gas diseases and preparation method thereof.
Background technology
In recent years, very high at winter-spring season gas diseases sickness rate, this disease seems usual but morbidity is rapid, can cause mortality, no matter is southern non-freezing water body, and still the ice-bound water body in the north all easily breaks out.The fry that gas bubble disease mostly occurs in pond culture, fingerling stage, but along with the continuous expansion of pond fish farming high yield area, the adult fish culture stage also often takes place.In addition, also easily suffer from this disease in the breed of the tilapia of batch production warm flow water breed and small size Carassius auratus.Particularly under the spray pool soon, gas bubble disease harm is the most serious, fry is more little responsive more, as rescues untimelyly, can cause the large quantities of death of fry, even all dead, adult fish also can be caused the mortality loss sometimes.Simultaneously, this disease is easily brought out Fish pernosis, fish molds, branchiomycosis, scale protrusion disease etc., causes the chronic death of winter-spring season.Break out frequently in the many culture zones of China at present, become the bottleneck of restriction Fish safe overwintering, be familiar with this sick pathogenic factor, grasp effective prophylactico-therapeutic measures and seem particularly important.
Therefore, providing a kind of medicine for preparing simple, obvious results control gas diseases and preparation method thereof, is one of this field scientific research technical staff important difficult problem of being badly in need of solving.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, medicine of a kind of reasonable recipe, simple, easy to use, the obvious results of preparation control gas diseases and preparation method thereof is provided.
The objective of the invention is to overcome deficiency of the prior art, a kind of pharmaceutical composition for the treatment of gas diseases is provided, said composition is utilized compatibility component function separately, and synergism reaches the purpose of cultivated animals prevention and resist the disease.
The technical solution adopted in the present invention is for achieving the above object:
A kind of medicine of preventing and treating gas diseases is characterized in that being made up of fully following mixed raw material by weight: Galla Chinensis 30-40 part, Radix Et Rhizoma Rhei 30-40 part, Sal 20-40 part.
A kind of preparation method of preventing and treating the medicine of gas diseases, concrete implementation step is as follows:
By described weight portion weighting raw materials Galla Chinensis 30-40 part, Radix Et Rhizoma Rhei 30-40 part; Total amount ratio 1:10-12 in crude drug adds water, soaks 20-30min, and decocts twice according to conventional method; The 30-40min of boiling back slow fire boiling for the first time filters; Filtering residue adds the water boiling back slow fire boiling 20-30min that 6-8 doubly measures again, filters; Merge filtrate twice, and then filter, it is 1.05-1.20 that temperature is concentrated into relative density 40 ℃ of-50 ℃ of following filtrates; At last, concentrated solution is cooled to room temperature; Take by weighing Sal 20-40 part then, slowly add in the concentrated solution, make its dissolving, packing, 5000ml/ bottle.
The characteristic of component of the present invention:
Galla Chinensis: sour, salty, flat.Have another name called gall nut, Mass Galla chinesis et camelliae Fermentata, hundred worm storehouses etc.; Be the dry insect gall on the lacquer section plant salt skin leaf originally, form by gallic aphid parasitism, contain a large amount of tannic acids, the energy solidifying protein, stronger sterilizing ability is arranged, Gram-positive and negative bacteria all there are inhibitory action, are used to prevent and treat white head and mouth fish disease, slime bacteria disease, Aeromonas disease, pseudomonas disease, white skin disease, erythroderma, furunculosis etc.
Radix Et Rhizoma Rhei: bitter in the mouth, cold.Return spleen, stomach, large intestine, liver, pericardium channel.Main effect has: heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Chemical constituent is mainly anthraquinone derivative in the Radix Et Rhizoma Rhei, mainly comprises anthraquinone glycoside and dianthracene quinone glycoside.Other contains tannin class material, organic acid and estrogen-like product etc.Radix Et Rhizoma Rhei has anti-infectious function, and multiple Gram-positive and negative bacteria are all had inhibitory action, and wherein the most responsive is staphylococcus and streptococcus.
Sal: formal name used at school sodium chloride, white crystals body.With its aqueous solution (concentration is generally 1%-4%) sick fish is carried out bathing, can treat bacillary fin rot disease, fish molds, squama is upright sick, trichodinasis, chilodoniasis, costiasis etc., as safe as a house.Sal can be regulated fish inside and outside osmotic pressure, allows the subcutaneous unnecessary gas of fish body be penetrated in the external water body.
The invention has the beneficial effects as follows: the present invention complements each other above-mentioned each component organic assembling, can bring into play the function of each component to greatest extent, really accomplishes " determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs "; Can either effectively treat gas bubble disease, can also prevent diseases such as the red skins of gas bubble disease ulceration secondary Fish and gill rot, reduce the aquatic animal sickness rate, increase and culture income, and preparation technology is simple, environmental protection, a kind of breed medicine of green is provided for market.
The specific embodiment
Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows for feature:
Every part of embodiment 1(is by 1kg)
A kind of medicine of preventing and treating gas diseases is made up of following mixed raw material: Galla Chinensis 30kg, Radix Et Rhizoma Rhei 30kg, Sal 40kg by weight fully.
Concrete preparation method is as follows: by described weight portion weighting raw materials Galla Chinensis 30kg, Radix Et Rhizoma Rhei 30kg, add water in the total amount ratio 1:12 of raw material, soak 20-30min, and decoct twice according to conventional method; The 30-40min of boiling back slow fire boiling for the first time filters; Filtering residue adds the water boiling back slow fire boiling 20-30min of 8 times of amounts again, filters; Merge filtrate twice, and then filter, it is 1.05-1.20 that temperature is concentrated into relative density 40 ℃ of-50 ℃ of following filtrates; At last, concentrated solution is cooled to room temperature; Take by weighing Sal 40kg then, slowly add in the concentrated solution, make its dissolving, packing, 5000ml/ bottle.
The various compositions that the present invention adopts are the commercially available prod; Wherein Galla Chinensis, Radix Et Rhizoma Rhei are pharmaceutical grade, and Sal is food stage.
Every part of embodiment 2(is by 1kg)
A kind of medicine of preventing and treating gas diseases is made up of following mixed raw material: Galla Chinensis 40kg, Radix Et Rhizoma Rhei 40kg, Sal 20kg by weight fully.
Concrete preparation method is as follows: by described weight portion weighting raw materials Galla Chinensis 40kg, Radix Et Rhizoma Rhei 40kg, add water in the total amount ratio 1:10 of raw material, soak 20-30min, and decoct twice according to conventional method; The 30-40min of boiling back slow fire boiling for the first time filters; Filtering residue adds the water boiling back slow fire boiling 20-30min of 6 times of amounts again, filters; Merge filtrate twice, and then filter, it is 1.05-1.20 that temperature is concentrated into relative density 40 ℃ of-50 ℃ of following filtrates; At last, concentrated solution is cooled to room temperature; Take by weighing Sal 20kg then, slowly add in the concentrated solution, make its dissolving, packing, 5000ml/ bottle.
Other is with embodiment 1.
Every part of embodiment 3(is by 1kg)
A kind of medicine of preventing and treating gas diseases is made up of following mixed raw material: Galla Chinensis 35kg, Radix Et Rhizoma Rhei 35kg, Sal 30kg by weight fully.
Concrete preparation method is as follows: by described weight portion weighting raw materials Galla Chinensis 35kg, Radix Et Rhizoma Rhei 35kg, add water in the total amount ratio 1:11 of raw material, soak 20-30min, and decoct twice according to conventional method; The 30-40min of boiling back slow fire boiling for the first time filters; Filtering residue adds the water boiling back slow fire boiling 20-30min of 7 times of amounts again, filters; Merge filtrate twice, and then filter, it is 1.05-1.20 that temperature is concentrated into relative density 40 ℃ of-50 ℃ of following filtrates; At last, concentrated solution is cooled to room temperature; Take by weighing Sal 30kg then, slowly add in the concentrated solution, make its dissolving, packing, 5000ml/ bottle.
Other is with embodiment 1.
Application experiment:
2008, the Hebei Tanghai had 8 mu of Megalobrama amblycephala wintering ponds, depth of water 1.3m, 400-5OOg/ tail; Beginning to occur Megalobrama amblycephala roaming under the ice face about January 20. the sick fish of roaming is sharply increased in two day time.Through going field observation, the water surface is most of icing thicker, and water quality is taupe, and transparency is low, fish body come-up, and it is not normal to move about.Fish for just dead sick fish soon, body surface, fin manifests many minute bubbles on the gill filament, confirm as gas bubble disease after diagnosing.Therapeutic scheme: earlier with the ice sheet fragmentation on the water surface of pond, simultaneously Chi Shui is discharged at 1/2 o'clock after; Every mu of consumption of culturing pond use product 2000ml of the present invention that the depth of water is 1 meter, the new water of annotating is to former water level, logotype 2-3 days, every day 1 time; The 4th day dead minimizing of sick fish, the state of an illness also is effectively controlled.When this product is used, answer full pool spilling head.
Above-mentioned detailed description of the medicine and preparation method thereof of control gas diseases being carried out with reference to embodiment; be illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (2)
1. a medicine of preventing and treating gas diseases is characterized in that being made up of fully following mixed raw material by weight: Galla Chinensis 30-40 part, Radix Et Rhizoma Rhei 30-40 part, Sal 20-40 part.
2. the preparation method of the medicine of a control gas diseases according to claim 1 is characterized in that concrete implementation step is as follows:
By described weight portion weighting raw materials Galla Chinensis 30-40 part, Radix Et Rhizoma Rhei 30-40 part; Total amount ratio 1:10-12 in crude drug adds water, soaks 20-30min, and decocts twice according to conventional method; The 30-40min of boiling back slow fire boiling for the first time filters; Filtering residue adds the water boiling back slow fire boiling 20-30min that 6-8 doubly measures again, filters; Merge filtrate twice, and then filter, it is 1.05-1.20 that temperature is concentrated into relative density 40 ℃ of-50 ℃ of following filtrates; At last, concentrated solution is cooled to room temperature; Take by weighing Sal 20-40 part then, slowly add in the concentrated solution, make its dissolving, packing, 5000ml/ bottle.
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CN2010102569786A CN101972314A (en) | 2010-08-19 | 2010-08-19 | Drug for controlling fish gas disease and preparation method thereof |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102225077A (en) * | 2011-06-23 | 2011-10-26 | 广西壮族自治区中国科学院广西植物研究所 | Application of Chinese gall extract for controlling streptococcal disease in aquaculture animals |
CN102764308A (en) * | 2012-08-14 | 2012-11-07 | 天津生机集团股份有限公司 | Drug for preventing bacterial diseases of fish and preparation method thereof |
CN103272005A (en) * | 2013-06-04 | 2013-09-04 | 江苏中洋集团股份有限公司 | Preparation method and application of Chinese herbal medicine for ecologically preventing and treating Australia dragon spot saprolegniasis |
CN103463280A (en) * | 2013-08-08 | 2013-12-25 | 泰州市春达动物药业饲料有限公司 | Fish bubble disease treatment drug composition and preparation method thereof |
CN103933184A (en) * | 2014-04-22 | 2014-07-23 | 湖州天健兽药有限公司 | Traditional Chinese medicine composition for treating white head-mouth disease of fishes |
CN107095955A (en) * | 2017-05-16 | 2017-08-29 | 云南海大生物科技有限公司 | A kind of the Chinese herb compound pre-mixing agent and environment protection type functional feed of prevention Tilapia mossambica gill rot |
-
2010
- 2010-08-19 CN CN2010102569786A patent/CN101972314A/en active Pending
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102225077A (en) * | 2011-06-23 | 2011-10-26 | 广西壮族自治区中国科学院广西植物研究所 | Application of Chinese gall extract for controlling streptococcal disease in aquaculture animals |
CN102225077B (en) * | 2011-06-23 | 2013-02-13 | 广西壮族自治区中国科学院广西植物研究所 | Application of Chinese gall extract for controlling streptococcal disease in aquaculture animals |
CN102764308A (en) * | 2012-08-14 | 2012-11-07 | 天津生机集团股份有限公司 | Drug for preventing bacterial diseases of fish and preparation method thereof |
CN103272005A (en) * | 2013-06-04 | 2013-09-04 | 江苏中洋集团股份有限公司 | Preparation method and application of Chinese herbal medicine for ecologically preventing and treating Australia dragon spot saprolegniasis |
CN103463280A (en) * | 2013-08-08 | 2013-12-25 | 泰州市春达动物药业饲料有限公司 | Fish bubble disease treatment drug composition and preparation method thereof |
CN103933184A (en) * | 2014-04-22 | 2014-07-23 | 湖州天健兽药有限公司 | Traditional Chinese medicine composition for treating white head-mouth disease of fishes |
CN103933184B (en) * | 2014-04-22 | 2016-08-31 | 湖州天健兽药有限公司 | A kind of Chinese medicine composition treating Fish white head and mouth fish disease |
CN107095955A (en) * | 2017-05-16 | 2017-08-29 | 云南海大生物科技有限公司 | A kind of the Chinese herb compound pre-mixing agent and environment protection type functional feed of prevention Tilapia mossambica gill rot |
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Application publication date: 20110216 |