The preparation method that is used for the virus bacterium blood serum Chinese aloe vaccine powder and the oral liquid of domestic animal, poultry and aquatic animal
[technical field]
The present invention relates to a kind of preparation method that is used for the immune formulation of domestic animal, poultry and aquatic animal, belong to the biological preparation field.
[background technology]
In recent years, human to domestic animal, the continuous increase of poultry and aquatic animal demand, and domestic animal, the growing environment of poultry and aquatic animal and feedstuff but more and more are subjected to various pollutions, make domestic animal, poultry and aquatic animal immunity degradation in growth course, various infection and disease often appear, having a strong impact on domestic animal, the growth of poultry and aquatic animal even large quantities of death, therefore urgent needs is a kind of can effectively improve domestic animal, poultry and the aquatic animal immunity in growth course is with various antibacterials in the opposing growth course, the infection of virus etc. and the infringement of various toxin.Thus, people have researched and developed immunological feed additive, the more immunological feed additive of current application is little ecological active bacteria formulation, to young animal and infected animal, has positive effect, but little ecological active bacteria formulation exists production and processing difficulty, the high shortcoming that is difficult to overcome of cost, for this reason, now is badly in need of a kind of additive or medicament that easy, action effect significantly improves immunity of producing.
[summary of the invention]
The present invention aims to provide a kind of easy method for preparing Aloe immunity powder and oral liquid, the product that makes is used for domestic animal, poultry and aquatic animal human body immunity improving power, resistance against diseases, anti-stress ability, thereby reduces domestic animal, poultry and aquatic animal mortality rate.
The preparation method of Chinese aloe vaccine powder of the present invention, concrete steps are:
(1) is respectively that the Aloe of 10-15: 1-2 and Fel Caprae seu Ovis are cleaned, mix the chopping back with mass ratio, adds 5-6 doubly to the white vinegar immersion mixture of mixture quality;
(2) steaming and decocting 1-3 hour, filter cooking liquor, the biological medicine Chinese medicine complex liquid of acquisition;
(3) concentrate drying complex liquid obtains pressed powder and is Chinese aloe vaccine powder.
The preparation method of Chinese aloe vaccine oral liquid of the present invention, concrete steps are:
(1) is respectively that the Aloe of 10-15: 1-2 and Fel Caprae seu Ovis are cleaned, mix the chopping back with mass ratio, adds 5-6 doubly to the white vinegar immersion mixture of mixture quality;
(2) steaming and decocting 1-3 hour, filter cooking liquor, the biological medicine Chinese medicine complex liquid of acquisition;
(3) concentrate drying complex liquid obtains pressed powder and is Chinese aloe vaccine powder.
(4) with 1000-2000 sterilized water dissolving powder doubly, obtain Aloe vaccine oral liquid
In above-mentioned two kinds of preparation methoies, the mass ratio of preferred Aloe and Fel Caprae seu Ovis is 13: 2.
The present invention is directed to the shortcoming of the immunity additive on the present market, research direction is positioned natural Chinese medicine, searching can effectively improve the immunity of animal can resist and kill various bacteria virus again, the material that growth of animal is not had simultaneously side effect again, and the Aloe very clear and bright person of this type of Chinese medicine material just.
As everyone knows, the tinctura aloes in the Aloe is the very strong material of antibiotic property, can kill pathogenic bacterias such as fungus, mycete, antibacterial, virus, the growth breeding of inhibition and eliminating pathogen; Slow ground state enzyme in the Aloe can be resisted inflammation; Polysaccharide in the Aloe can strengthen the resistance of animal to disease; 1-Hydroxy-1,2,3-propanetricarboxylic acid. calcium in the Aloe etc. has the effect of heart tonifying, blood circulation promoting, softening pipe-stem arteries, expansion blood capillary, makes blood circulation unimpeded, reduces cholesterol value, alleviates the heart burden, makes blood pressure keep normal, removes " toxin " in the blood; Aloin A in the Aloe, wound hormone and polysaccharide peptide manna (Ke-2) etc. have viral infection resisting, promote the restorative effect of wound healing, and the function of anti-inflammation and sterilization, heat absorption detumescence, softening skin, maintenance cell viability is arranged; Thick substances polysaccharide in the Aloe (acetylated glucomannan, mannan, acemannan, aloe mannan, alocutin, alomicin etc.) has the effect that improves immunity and inhibition, the paracytic growth of destruction, thereby reaches the various infection purposes of opposing.
The Chinese aloe vaccine oral liquid (powder) of domestic animal of the present invention, poultry and aquatic animal, has heat-clearing and toxic substances removing, collaborative counteracting toxic substances, pathogenic fire purging, cleaning endotoxin, anti-inflammation, blood stasis dispersing and deswelling, but be good for the stomach, function of gallbladder promoting, sharp larynx kill the virus the control characteristic of disease, prevent accompanying infection, human body immunity improving power effect.Obviously mitigation symptoms, disease controlling worsen especially at the initial stage of a disease, effectively prevent the mixed infection of concurrency bird flu virus.
Chinese aloe vaccine oral liquid of the present invention (powder), its mechanism of action are to stop virus to penetrate host cell, and the shelling of influence virus, reach the virus multiplication effect that suppresses.
Chinese aloe vaccine oral liquid of the present invention, the drinking-water convenient drug administration, the absorbance height, widely distributed, drug residue free has no side effect, and safety range is wide.
Preparation method of the present invention, the product that process is simple, easy to operate, can obtain the high concentration high yield, and also pollution-free to environment.
[specific embodiment]
Embodiment one: Chinese aloe vaccine powder
(1) respectively the back is cleaned, shredded to 10Kg Aloe and the commercially available Fel Caprae seu Ovis of 1Kg and mix, use the white vinegar immersion mixture of 55L then.
(2) steaming and decocting is 3 hours, cooled and filtered cooking liquor, the biological medicine Chinese medicine complex liquid of acquisition.
(3) adopt ultra concentration and drying equipment that above-mentioned complex liquid is concentrated with dry, obtain the 3Kg Chinese aloe vaccine powder.
Embodiment two: the Chinese aloe vaccine oral liquid
(1) respectively the back is cleaned, shredded to 13Kg Aloe and the commercially available Fel Caprae seu Ovis of 2Kg and mix, use the white vinegar immersion mixture of 85L then.
(2) steaming and decocting is 3 hours, cooled and filtered cooking liquor, the biological medicine Chinese medicine complex liquid of acquisition.
(3) adopt ultra concentration and drying equipment that above-mentioned complex liquid is concentrated with dry, obtain the 4Kg Chinese aloe vaccine powder.
(4) get the 1Kg Chinese aloe vaccine powder and be dissolved in the 1000L sterilized water, obtain concentration and be 0.1% Chinese aloe vaccine oral liquid.
Embodiment three: the Chinese aloe vaccine oral liquid is to the influence of domestic animal effect
From the pig that suffers from asthma, choose body weight and developmental phase with near 30, be divided into three groups at random, oral long-acting terramycin powder, 30 mg/kg body weight, every day 1 time.Wherein do not add any immunizing agent in the oxytetracycline powder of A group, the B group is added commercially available immunizing agent (addition is 0.3%), and the C group is added the Chinese aloe vaccine powder (addition is 0.3%) that embodiment two makes.
After three days, A group improvement rate is 30%, B group improvement rate is 40%, C group improvement rate is 80%;
After seven days, A group cure rate is 70%, B group cure rate is 75%, C group cure rate is 90%.
The result shows that Chinese aloe vaccine powder of the present invention can effectively promote the intravital biological transformation ratio of domestic animal of medicine, improves immunity and the drug effect of domestic animal.
Embodiment four: Chinese aloe vaccine powder is to the influence of poultry effect
150 similar young chickens of growing state are divided into three groups at random, A organizes direct feed for nursing (not containing other drug), and the B group is added 0.01% commercially available immunizing agent in feedstuff, and the C group is added the Chinese aloe vaccine powder that 0.01% embodiment two makes in feedstuff, observe after one month result such as table 1.
Table 1 Chinese aloe vaccine powder is to the influence of poultry effect
|
Eating speed |
Rate of body weight gain (%) |
Prevalence (%) |
The A group |
Normally |
58 |
9 |
The B group |
Normally |
61 |
7 |
The C group |
Normally |
89 |
2 |
The result shows that Chinese aloe vaccine powder of the present invention can effectively improve immunity, the anti-virus ability of poultry, promotes the growth of poultry.
Embodiment five: the Chinese aloe vaccine oral liquid is to the influence of aquatic animal effect
600 similar juvenile prawns of growing state are divided into three groups at random, the A group is not added any immunizing agent in feedstuff, the B group is added 0.2% commercially available immunizing agent in feedstuff, the Chinese aloe vaccine oral liquid that the embodiment two of C group interpolation 0.2% in feedstuff makes, observe after one month result such as table 2.
Table 2 Chinese aloe vaccine oral liquid is to the influence of aquatic animal effect
|
Eating speed |
Rate of body weight gain (%) |
Prevalence (%) |
The A group |
Normally |
94 |
8 |
The B group |
Normally |
113 |
9 |
The C group |
Normally |
133 |
2 |
The result shows that Chinese aloe vaccine oral liquid of the present invention can effectively improve immunity, the anti-virus ability of aquatic animal, promotes the growth of aquatic animal.