CN102283886A - Composition for treating proventriculitis of poultry and preparation method thereof - Google Patents
Composition for treating proventriculitis of poultry and preparation method thereof Download PDFInfo
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- CN102283886A CN102283886A CN2011102102699A CN201110210269A CN102283886A CN 102283886 A CN102283886 A CN 102283886A CN 2011102102699 A CN2011102102699 A CN 2011102102699A CN 201110210269 A CN201110210269 A CN 201110210269A CN 102283886 A CN102283886 A CN 102283886A
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- radix astragali
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Abstract
The invention provides a composition for treating proventriculitis of poultry and a preparation method thereof. The composition comprises the following components in part by weight: 10 to 30 parts of astragalus extract, 10 to 15 parts of penicillin industrial salt, 1 to 10 parts of ranitidine, 1 to 2 parts of vitamin B1, 1 to 2 parts of vitamin B2, 1 to 2 parts of vitamin B6 and 20 to 60 parts of glucosum anhydricum. The preparation method comprises the following steps of: adding cellulase in an amount which is 0.5 percent into astragalus, immersing for 24 hours, decocting, standing, extracting supernate, concentrating until the density is between 1.0 and 1.3, adding cane sugar to obtain a soft material, and drying and crushing to obtain the astragalus extract; and packaging the astragalus extract in separate bags A individually, mixing other ingredients uniformly in a ratio, packaging in separate bags B, and merging the bags A and B. During treatment, 50 grams of the composition is added into each 100 kilograms of water, and is drunk by chickens freely and continuously for 3 to 5 days. The composition has the effective treatment effect on damage caused by bacteria, virus and immunodepression.
Description
Technical field
The invention belongs to the birds medicine, especially a kind of composition and method of making the same for the treatment of the fowl proventriculitis.
Background technology
The fowl proventriculitis is especially a kind of common frdquently encountered disease of broiler of present poultry, its pathogenic factor complexity, therapeutic effect is undesirable, contains foreign body in how poor because of feeding quality, the feedstuff or is caused by mould contamination, immunosuppressive disease, viral disease, bacterial infection etc., causes growth promoter slow, feed conversion rate reduces, the poultry feed intake reduces, and becomes stiff chicken, and resistance descends, and other various diseases of secondary bring very big economic loss to the raiser easily.Therefore, research and develop a kind of medicine that can effectively treat the fowl proventriculitis, have very important production practices meaning.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of composition and method of making the same for the treatment of the fowl proventriculitis, have the little and lower-cost characteristics of toxicity, can play effective therapeutical effect to the infringement that antibacterial, virus, immunosuppressant cause, also strengthen the anti-adversity ability of birds body simultaneously.
For solving the problems of the technologies described above, technical scheme of the present invention is: a kind of compositions for the treatment of the fowl proventriculitis comprises Radix Astragali extract, penicillin Nacl, ranitidine, vitamin B
1, vitamin B
2, vitamin B
6, anhydrous glucose, by its parts by weight Radix Astragali extract 10-30 part, penicillin Nacl 10-15 part, ranitidine 1-10 part, vitamin B
11-2 part, vitamin B
21-2 part, vitamin B
61-2 part, anhydrous glucose 20-60 part.
Preferably, the drug composition of above-mentioned fowl proventriculitis is by 10 parts of its parts by weight Radix Astragali extracts, 10 parts of penicillin Nacls, 8 parts of ranitidines, vitamin B
11 part, vitamin B
21 part, vitamin B
650 parts of 1 parts, anhydrous glucose.
Preferably, the compositions of above-mentioned treatment fowl proventriculitis is by 10 parts of its parts by weight Radix Astragali extracts, 10 parts of penicillin Nacls, 10 parts of ranitidines, vitamin B
12 parts, vitamin B
22 parts, vitamin B
650 parts of 1 parts, anhydrous glucose.
Preferably, the compositions of above-mentioned treatment fowl proventriculitis is by 10 parts of its parts by weight Radix Astragali extracts, 10 parts of penicillin Nacls, 1 part of ranitidine, vitamin B
11 part, vitamin B
21 part, vitamin B
620 parts of 1 parts, anhydrous glucose.
Preferably, the compositions of above-mentioned treatment fowl proventriculitis is by 30 parts of its parts by weight Radix Astragali extracts, 15 parts of penicillin Nacls, 10 parts of ranitidines, vitamin B
12 parts, vitamin B
22 parts, vitamin B
660 parts of 2 parts, anhydrous glucose.
Preferably, the compositions of above-mentioned treatment fowl proventriculitis is by 20 parts of its parts by weight Radix Astragali extracts, 10 parts of penicillin Nacls, 5 parts of ranitidines, vitamin B
11 part, vitamin B
21 part, vitamin B
660 parts of 1 parts, anhydrous glucose.
Preferably, the compositions of above-mentioned treatment fowl proventriculitis is by 20 parts of its parts by weight Radix Astragali extracts, 15 parts of penicillin Nacls, 8 parts of ranitidines, vitamin B
12 parts, vitamin B
21 part, vitamin B
640 parts of 1 parts, anhydrous glucose.
Preferably, the compositions of above-mentioned treatment fowl proventriculitis is by 25 parts of its parts by weight Radix Astragali extracts, 12 parts of penicillin Nacls, 5 parts of ranitidines, vitamin B
12 parts, vitamin B
22 parts, vitamin B
650 parts of 2 parts, anhydrous glucose.
The preparation of compositions method of above-mentioned treatment fowl proventriculitis, concrete preparation process is as follows:
(1) Radix Astragali is added cellulase in 0.5% ratio and soaked 24 hours, and decoct, leave standstill and be concentrated into relative density 1.0～1.3 after getting supernatant, add sucrose and make soft material, drying and crushing promptly gets Radix Astragali extract, independently is packed as the A bag;
(2) get penicillin Nacl, vitamin B by above-mentioned parts by weight
1, vitamin B
2, vitamin B
6, ranitidine, anhydrous glucose be raw material, is packed as the B bag after fully mixing;
(3) merge two bags of A, B by above-mentioned parts by weight, promptly.
Preferably, the preparation of compositions method of above-mentioned treatment fowl proventriculitis, wherein the A bag is for being the brownish red powder, feeble QI perfume (or spice), it is sweet to distinguish the flavor of, and the B bag is white or off-white powder.
The preparation of compositions method of above-mentioned treatment fowl proventriculitis, the dosage form of the compositions that described step is made is a powder.
The compositions that the preparation of compositions method of above-mentioned treatment fowl proventriculitis is made when being used for the treatment of the fowl proventriculitis, adds said composition 50g by the every 100kg water of chicken, and logotype 3～5 days was a course of treatment.
The invention has the beneficial effects as follows:
(1) compositions toxicity of the present invention is little, and cost is lower, can play effective therapeutical effect to the infringement that antibacterial, virus, immunosuppressant cause, and goes back the anti-adversity ability of enhancing body simultaneously;
(2) compositions of the present invention is simple to operate, easy to use, and a people can operate;
(3) preparation method of the present invention is simple, is fit to requirements of large-scale industrial production.
The specific embodiment
Below in conjunction with specific embodiment technical scheme of the present invention is further described.
Embodiment 1
A kind of compositions for the treatment of the fowl proventriculitis comprises Radix Astragali extract, penicillin Nacl, ranitidine, vitamin B
1, vitamin B
2, vitamin B
6, anhydrous glucose, concrete preparation method is as follows:
(1) Radix Astragali is added cellulase in 0.5% ratio and soaked 24 hours, and decoct, leave standstill and be concentrated into relative density 1.3 after getting supernatant, add sucrose and make soft material, drying and crushing promptly gets Radix Astragali extract, and this extract is the brownish red powder, feeble QI perfume (or spice), it is sweet to distinguish the flavor of, and independently is packed as the A bag;
(2) get 10 parts of penicillin Nacls, 8 parts of ranitidines, vitamin B by weight
11 part, vitamin B
21 part, vitamin B
61 part, anhydrous glucose are raw material for 50 parts, are packed as the B bag after fully mixing;
(3) get 10 parts of Radix Astragali extracts, 10 parts of penicillin Nacls, 8 parts of ranitidines, vitamin B by weight
11 part, vitamin B
21 part, vitamin B
650 parts of 1 parts, anhydrous glucose merge two bags of A, B, promptly.
Embodiment 2
A kind of compositions for the treatment of the fowl proventriculitis comprises Radix Astragali extract, penicillin Nacl, ranitidine, vitamin B
1, vitamin B
2, vitamin B
6, anhydrous glucose, concrete preparation method is as follows:
(1) Radix Astragali is added cellulase in 0.5% ratio and soaked 24 hours, and decoct, leave standstill and be concentrated into relative density 1.2 after getting supernatant, add sucrose and make soft material, drying and crushing promptly gets Radix Astragali extract, independently is packed as the A bag;
(2) get 10 parts of penicillin Nacls, 10 parts of ranitidines, vitamin B by weight
12 parts, vitamin B
22 parts, vitamin B
61 part, anhydrous glucose are raw material for 50 parts, are packed as the B bag after fully mixing;
(3) get 10 parts of Radix Astragali extracts, 10 parts of penicillin Nacls, 10 parts of ranitidines, vitamin B by weight
12 parts, vitamin B
22 parts, vitamin B
650 parts of 1 parts, anhydrous glucose merge two bags of A, B, promptly.
Embodiment 3
A kind of compositions for the treatment of the fowl proventriculitis comprises Radix Astragali extract, penicillin Nacl, ranitidine, vitamin B
1, vitamin B
2, vitamin B
6, anhydrous glucose, concrete preparation method is as follows:
(1) Radix Astragali is added cellulase in 0.5% ratio and soaked 24 hours, and decoct, leave standstill and be concentrated into relative density 1.3 after getting supernatant, add sucrose and make soft material, drying and crushing promptly gets Radix Astragali extract, independently is packed as the A bag;
(2) get 10 parts of penicillin Nacls, 1 part of ranitidine, vitamin B by weight
11 part, vitamin B
21 part, vitamin B
61 part, anhydrous glucose are raw material for 20 parts, are packed as the B bag after fully mixing;
(3) get 10 parts of Radix Astragali extracts, 10 parts of penicillin Nacls, 1 part of ranitidine, vitamin B by weight
11 part, vitamin B
21 part, vitamin B
620 parts of 1 parts, anhydrous glucose merge two bags of A, B, promptly.
Embodiment 4
A kind of compositions for the treatment of the fowl proventriculitis comprises Radix Astragali extract, penicillin Nacl, ranitidine, vitamin B
1, vitamin B
2, vitamin B
6, anhydrous glucose, concrete preparation method is as follows:
(1) Radix Astragali is added cellulase in 0.5% ratio and soaked 24 hours, and decoct, leave standstill and be concentrated into relative density 1.1 after getting supernatant, add sucrose and make soft material, drying and crushing promptly gets Radix Astragali extract, independently is packed as the A bag;
(2) get 15 parts of penicillin Nacls, 10 parts of ranitidines, vitamin B by weight
12 parts, vitamin B
22 parts, vitamin B
62 parts, anhydrous glucose are raw material for 60 parts, are packed as the B bag after fully mixing;
(3) get 30 parts of Radix Astragali extracts, 15 parts of penicillin Nacls, 10 parts of ranitidines, vitamin B by weight
12 parts, vitamin B
22 parts, vitamin B
660 parts of 2 parts, anhydrous glucose merge two bags of A, B, promptly.
Embodiment 5
A kind of compositions for the treatment of the fowl proventriculitis comprises Radix Astragali extract, penicillin Nacl, ranitidine, vitamin B
1, vitamin B
2, vitamin B
6, anhydrous glucose, concrete preparation method is as follows:
(1) Radix Astragali is added cellulase in 0.5% ratio and soaked 24 hours, and decoct, leave standstill and be concentrated into relative density 1.3 after getting supernatant, add sucrose and make soft material, drying and crushing promptly gets Radix Astragali extract, independently is packed as the A bag;
(2) get 10 parts of penicillin Nacls, 5 parts of ranitidines, vitamin B by weight
11 part, vitamin B
21 part, vitamin B
61 part, anhydrous glucose are raw material for 60 parts, are packed as the B bag after fully mixing;
(3) get 20 parts of Radix Astragali extracts, 10 parts of penicillin Nacls, 5 parts of ranitidines, vitamin B by weight
11 part, vitamin B
21 part, vitamin B
660 parts of 1 parts, anhydrous glucose merge two bags of A, B, promptly.
Embodiment 6
A kind of compositions for the treatment of the fowl proventriculitis comprises Radix Astragali extract, penicillin Nacl, ranitidine, vitamin B
1, vitamin B
2, vitamin B
6, anhydrous glucose, concrete preparation method is as follows:
(1) Radix Astragali is added cellulase in 0.5% ratio and soaked 24 hours, and decoct, leave standstill and be concentrated into relative density 1.3 after getting supernatant, add sucrose and make soft material, drying and crushing promptly gets Radix Astragali extract, independently is packed as the A bag;
(2) get 15 parts of penicillin Nacls, 8 parts of ranitidines, vitamin B by weight
12 parts, vitamin B
21 part, vitamin B
61 part, anhydrous glucose are raw material for 40 parts, are packed as the B bag after fully mixing;
(3) get 20 parts of Radix Astragali extracts, 15 parts of penicillin Nacls, 8 parts of ranitidines, vitamin B by weight
12 parts, vitamin B
21 part, vitamin B
640 parts of 1 parts, anhydrous glucose merge two bags of A, B, promptly.
Embodiment 7
A kind of compositions for the treatment of the fowl proventriculitis comprises Radix Astragali extract, penicillin Nacl, ranitidine, vitamin B
1, vitamin B
2, vitamin B
6, anhydrous glucose, concrete preparation method is as follows:
(1) Radix Astragali is added cellulase in 0.5% ratio and soaked 24 hours, and decoct, leave standstill and be concentrated into relative density 1.0 after getting supernatant, add sucrose and make soft material, drying and crushing promptly gets Radix Astragali extract, independently is packed as the A bag;
(2) get 12 parts of penicillin Nacls, 5 parts of ranitidines, vitamin B by weight
12 parts, vitamin B
22 parts, vitamin B
62 parts, anhydrous glucose are raw material for 50 parts, are packed as the B bag after fully mixing;
(3) get 25 parts of Radix Astragali extracts, 12 parts of penicillin Nacls, 5 parts of ranitidines, vitamin B by weight
12 parts, vitamin B
22 parts, vitamin B
650 parts of 2 parts, anhydrous glucose merge two bags of A, B, promptly.
In the compositions of above-mentioned treatment fowl proventriculitis, the Radix Astragali, penicillin Nacl, vitamin B
1, vitamin B
2, vitamin B
6, ranitidine, anhydrous glucose all meet the relevant regulations in " Chinese veterinary drug allusion quotation ".
The Radix Astragali has the effect of invigorating qi and benefiting blood in the compositions of above-mentioned treatment fowl proventriculitis, but its extract human body immunity improving power, and especially the pair cell immunity has good regulating action, improves the immune function of body, the enhancing body resistance against diseases; Vitamin B group has the function of good facilitating digestion and absorption, reduces the zest of feedstuff to coat of the stomach; The penicillin Nacl can be eliminated bacterial infection, the antiinflammatory degerming; Ranitidine suppresses glandular secretion, reduces gastric acid secretion, and repairing ulcer makes whole prescription mend, support, control in one, makes therapeutical effect strengthen greatly, and the anti-adversity ability of enhancing body significantly improves therapeutic effect and cure rate simultaneously.
The fowl proventriculitis is a kind of disease that makes the headache of raiser in recent years in the poultry farming, the bad feedstuff of various pathogens and stressors, vaccine and quality all can cause, make the poultry growth promoter slow, feed conversion rate reduces, emaciated physique, prolong marketing time, susceptibility to disease strengthens, bring very big loss to the raiser, all can take place throughout the year, for inquiring into the effective way of control fowl proventriculitis, the selection medication of science, the medicine of selecting to have invigorating the spleen and replenishing QI, anti-inflammation, repairing ulcer, facilitating digestion carries out prescription, and clinical trial is as follows:
Clinical trial 1
It is depressed that spirit takes place 5000 21 age in days broiler chicken of Tianjin Yang Gezhuan raiser Wang raising in 2009, and feed intake descends, and drinking-water increases, feces is thinning, contains indigested feed granules, the mortality rate height, the feather pine disorderly, skeletonize is cutd open visible glandular stomach swelling of inspection such as table tennis, the quality hardening, the muscular stomach horny layer is easy to peel off, and visible ulcer, according to clinical symptoms, tentative diagnosis is the fowl proventriculitis.
Treatment: the compositions with embodiment 1 described treatment fowl proventriculitis is treated, and adds said composition 50g by every 100kg drinking-water during treatment, and 1 day once, freely drink, logotype 3 days, mortality rate descends, be almost recovered after 5 days, adopt the diffusing spice of strong chicken subsequently again, promote growth.
Clinical trial 2
In March, 2010,5000 AA broiler chicken morbidities that Mare Tranquillitatis, Tianjin Zhang raises, it is fluffy and disorderly that the master shows feather clinically, be a cup too low, wing is sagging, and feed intake and amount of drinking water obviously reduce, the chicken eye symptom of shedding tears and swell, and with respiratory symptom, row's white and green loose stool.Cut open inspection visible sick chicken glandular stomach enlargement such as ball, be creamy white, examine visible canescence trellis outward appearance, cut the visible glandular stomach wall thickening of glandular stomach, edema, one by flowing out serosity liquid gently.Nipple swelling is hemorrhage, and the nipple boundary merges, and not have boundary can be divided.The muscular stomach atrophy, thymus, the serious atrophy of spleen.Intestinal shows mucosa and breaks away from bleeding.According to clinical manifestation and cut open inspection and change, tentative diagnosis is the fowl proventriculitis.
Treatment: the compositions with embodiment 1 described treatment fowl proventriculitis is treated, and adds said composition 50g by every 100kg drinking-water during treatment, 1 day once concentrated drinking, logotype 3 days, recovery from illness.
Above-mentioned detailed description of this a kind of composition and method of making the same for the treatment of the fowl proventriculitis being carried out with reference to embodiment; be illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (10)
1. a compositions for the treatment of the fowl proventriculitis is characterized in that: comprise Radix Astragali extract, penicillin Nacl, ranitidine, vitamin B
1, vitamin B
2, vitamin B
6, anhydrous glucose, by its parts by weight Radix Astragali extract 10-30 part, penicillin Nacl 10-15 part, ranitidine 1-10 part, vitamin B
11-2 part, vitamin B
21-2 part, vitamin B
61-2 part, anhydrous glucose 20-60 part.
2. the compositions of treatment fowl proventriculitis according to claim 1 is characterized in that: by 10 parts of its parts by weight Radix Astragali extracts, 10 parts of penicillin Nacls, 8 parts of ranitidines, vitamin B
11 part, vitamin B
21 part, vitamin B
650 parts of 1 parts, anhydrous glucose.
3. the compositions of treatment fowl proventriculitis according to claim 1 is characterized in that: by 10 parts of its parts by weight Radix Astragali extracts, 10 parts of penicillin Nacls, 10 parts of ranitidines, vitamin B
12 parts, vitamin B
22 parts, vitamin B
650 parts of 1 parts, anhydrous glucose.
4. the compositions of treatment fowl proventriculitis according to claim 1 is characterized in that: by 10 parts of its parts by weight Radix Astragali extracts, 10 parts of penicillin Nacls, 1 part of ranitidine, vitamin B
11 part, vitamin B
21 part, vitamin B
620 parts of 1 parts, anhydrous glucose.
5. the compositions of treatment fowl proventriculitis according to claim 1 is characterized in that: by 30 parts of its parts by weight Radix Astragali extracts, 15 parts of penicillin Nacls, 10 parts of ranitidines, vitamin B
12 parts, vitamin B
22 parts, vitamin B
660 parts of 2 parts, anhydrous glucose.
6. the compositions of treatment fowl proventriculitis according to claim 1 is characterized in that: by 20 parts of its parts by weight Radix Astragali extracts, 10 parts of penicillin Nacls, 5 parts of ranitidines, vitamin B
11 part, vitamin B
21 part, vitamin B
660 parts of 1 parts, anhydrous glucose.
7. the compositions of treatment fowl proventriculitis according to claim 1 is characterized in that: by 20 parts of its parts by weight Radix Astragali extracts, 15 parts of penicillin Nacls, 8 parts of ranitidines, vitamin B
12 parts, vitamin B
21 part, vitamin B
640 parts of 1 parts, anhydrous glucose.
8. the compositions of treatment fowl proventriculitis according to claim 1 is characterized in that: by 25 parts of its parts by weight Radix Astragali extracts, 12 parts of penicillin Nacls, 5 parts of ranitidines, vitamin B
12 parts, vitamin B
22 parts, vitamin B
650 parts of 2 parts, anhydrous glucose.
9. according to the preparation of compositions method of the described treatment of one of claim 1-8 fowl proventriculitis, it is characterized in that: concrete preparation process is as follows:
(1) get the Radix Astragali, the cellulase of interpolation 0.5% soaked 24 hours, and decocted 1.5 hours, left standstill 24 hours, be concentrated into relative density 1.0～1.3 after getting supernatant, add sucrose and make soft material, the drying and crushing powdered, and, promptly get Radix Astragali extract by 60 mesh sieves, independently be packed as the A bag;
(2) get penicillin Nacl, vitamin B by above-mentioned parts by weight
1, vitamin B
2, vitamin B
6, ranitidine, anhydrous glucose be raw material, is packed as the B bag after fully mixing;
(3) merge two bags of A, B by above-mentioned parts by weight, promptly.
10. the preparation of compositions method of treatment according to claim 9 fowl proventriculitis is characterized in that: wherein the A bag is for being the brownish red powder, feeble QI perfume (or spice), and it is sweet to distinguish the flavor of, and the B bag is white or off-white powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN2011102102699A CN102283886A (en) | 2011-07-26 | 2011-07-26 | Composition for treating proventriculitis of poultry and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011102102699A CN102283886A (en) | 2011-07-26 | 2011-07-26 | Composition for treating proventriculitis of poultry and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103394021A (en) * | 2013-08-05 | 2013-11-20 | 山东新希望六和集团有限公司 | Compound medicament for treating proventriculitis and gizzard erosion of poultry and preparation method thereof |
| CN104666429A (en) * | 2013-11-28 | 2015-06-03 | 天津瑞贝特科技发展有限公司 | Composition for treating proventriculitis of chicken and preparation method of composition |
| CN108671013A (en) * | 2018-07-31 | 2018-10-19 | 济南佑生生物工程有限公司 | A kind of drug for preventing poultry mould sexual gland, ventriculitis |
-
2011
- 2011-07-26 CN CN2011102102699A patent/CN102283886A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103394021A (en) * | 2013-08-05 | 2013-11-20 | 山东新希望六和集团有限公司 | Compound medicament for treating proventriculitis and gizzard erosion of poultry and preparation method thereof |
| CN103394021B (en) * | 2013-08-05 | 2015-03-25 | 山东新希望六和集团有限公司 | Compound medicament for treating proventriculitis and gizzard erosion of poultry and preparation method thereof |
| CN104666429A (en) * | 2013-11-28 | 2015-06-03 | 天津瑞贝特科技发展有限公司 | Composition for treating proventriculitis of chicken and preparation method of composition |
| CN108671013A (en) * | 2018-07-31 | 2018-10-19 | 济南佑生生物工程有限公司 | A kind of drug for preventing poultry mould sexual gland, ventriculitis |
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Application publication date: 20111221 |