CN101306180A

CN101306180A - Gastropathy treating medicine

Info

Publication number: CN101306180A
Application number: CNA2008103020798A
Authority: CN
Inventors: 王立财
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-06-10
Filing date: 2008-06-10
Publication date: 2008-11-19
Anticipated expiration: 2028-06-10
Also published as: CN101306180B

Abstract

The invention relates to a Chinese traditional preparation, namely, a medicine used for curing stomach trouble. The Chinese traditional preparation is prepared with effective ingredients and medically acceptable auxiliary materials. The Chinese traditional preparation is characterized in that the effective ingredients of the Chinese traditional preparation is prepared with the following raw materials by weight part: 10 to 30 parts of cuttlebone, 10 to 30 parts of concha arcae, 5 to 30 parts of fructus amomi, 15 to 50 parts of chicken gizzard membrane, 20 to 40 parts of hyacinth bletilla, and 15 to 20 parts of tuber pinellia. Granules are taken as example. The granules taken directly stick to the stomach wall and the tunica mucosa ventriculi so that the injured tunica mucosa ventriculi are repaired quickly, and campylobacter pybridis is killed quickly. Accordingly, the Chinese traditional preparation has excellent curative effect. The Chinese traditional preparation shows satisfactory results through the tests on 296 stomach trouble sufferers who have taken the Chinese traditional preparation. The formula of the Chinese traditional preparation is simple, and the Chinese traditional preparation takes effect quickly, and has lasting action with small toxic and side effect. The overall effective rate is more than 98%.

Description

A kind of medicine for the treatment of gastropathy

Technical field

The present invention relates to a kind of Chinese medicine preparation, promptly a kind of medicine for the treatment of gastropathy.

Background technology

In prior art, the pharmaceutical composition of treatment gastropathy is of a great variety, and prescription, curative effect is different, discloses a kind of name on October 4th, 2006 as the Chinese invention patent prospectus and has been called " a kind of medicine for the treatment of gastropathy " application for a patent for invention, number of patent application 200610001096.9, this medicine be by the Radix Aucklandiae, Rhizoma Cyperi, Semen Arecae, Fructus Aurantii, Radix Curcumae, Pericarpium Citri Reticulatae Viride, Flos Carthami, the Radix Linderae, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Os Sepiae, Rhizoma Corydalis, Rhizoma Atractylodis, Radix agastaches, Fructus Hordei Germinatus (parched), Endothelium Corneum Gigeriae Galli, Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Folium Isatidis 19 flavor Chinese herbal medicine are formed.Main treatment flatulence expires and pain, meets cold pain play, meets Wen Zehuan, and the stagnation of QI is counter belches, lack of appetite and anorexia; Glutted hungry pain is anxious, chronic gastritis, diseases such as duodenitis and ulcer.Its shortcoming is the prescription complexity, the cost height.

Summary of the invention

The objective of the invention is provides a kind of prescription simple at above-mentioned deficiency, and curative effect is treated the medicine of gastropathy reliably.

Technical solution of the present invention is: it is made the medicine of treatment gastropathy by effective ingredient and acceptable accessories, it is characterized in that effective ingredient wherein made by following weight crude drug: Endoconcha Sepiae 10-30 part, Concha Arcae 10-30 part, Fructus Amomi 5-30 part, Endothelium Corneum Gigeriae Galli 15-50 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-40 part, Rhizoma Pinelliae 15-20 part.

10 parts of preferred Endoconcha Sepiaes, 10 parts of Concha Arcaes, 30 parts of Fructus Amomis, 15 parts of Endothelium Corneum Gigeriae Galli, 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of the Rhizoma Pinelliaes.

Can be mixed and made into tablet, capsule (soft capsule), granule, powder, pill or other conventional formulation by pharmaceutical carrier, additive or adjuvant commonly used in above-mentioned each medicinal raw material and the pharmacy.

The Pseudobulbus Bletillae (Rhizoma Bletillae) is a monarch drug, and astringing to arrest bleeding, muscle-growing and detumescence are arranged, and closing up, it is the main medication of surgery.Endoconcha Sepiae, Concha Arcae: but all antacid of two medicines, and stomachache, hyperchlorhydria glue the accessory drugs of touching that act as with repairing stomach.The Rhizoma Pinelliae, Fructus Amomi: spleen invigorating, stomach function regulating fall and send preventing or arresting vomiting, and all stomaches are sticking touches damage, the stagnation of QI in spleen and stomach person all can cause vomiting, and wherein the Rhizoma Pinelliae can be removed the adjuvant drug that effect is thought of vomiting.Endothelium Corneum Gigeriae Galli: the kind food stagnation of controlling is stagnated flatulence, the belch that causes, is messenger drug.

The preparation method of the medicine of described treatment gastropathy, step is as follows:

(1) pulverize Concha Arcae, Endoconcha Sepiae standby;

(2) Fructus Amomi, Endothelium corneum, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Rhizoma Pinelliae are decocted with water three times, each 2 hours time, merge and mix with Concha Arcae, Endoconcha Sepiae powder after medicine juice is condensed into extractum, drying, pulverizing, make dosage form.

Function with cure mainly: have a stomach-ache, vomit, do not think food, abdominal distention, gastric cancer, chronic gastritis, gastric ulcer, superficial gastritis, erosive gastritis, antral gastritis, bile reflux gastritis, stomach spasm, diaphragm muscular spasm, peptic ulcer, duodenal ulcer etc. after meal.The 3-30 days course of treatment.

Advantage of the present invention is: be example with the granule 1,, taking can directly go to live in the household of one's in-laws on getting married in the stomach pastes coat of the stomach, is obeying gastric mucosa, and impaired gastric mucosa is repaired fast, kills campylobacter pyloridis fast, so curative effect is excellent.2, this medicine is taken through clinical 296 patients with gastric disease, and result of the test is satisfactory, and this medicine prescription is simple, instant effect, effect are lasting, and toxic and side effects is little, and total effective rate can reach more than 98%.

Below in conjunction with embodiment embodiments of the present invention are described in further detail.

The specific embodiment

Embodiment 1

A kind of medicine for the treatment of gastropathy, it is made by effective ingredient and acceptable accessories, and effective ingredient is wherein made dosage form by following weight crude drug: 20 parts of Endoconcha Sepiaes, 20 parts of Concha Arcaes, 15 parts of Fructus Amomis, 20 parts of Endothelium Corneum Gigeriae Galli, 30 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 18 parts of the Rhizoma Pinelliaes.

Embodiment 2

A kind of medicine for the treatment of gastropathy, it is made by effective ingredient and acceptable accessories, and effective ingredient is wherein made dosage form by following weight crude drug: 10 parts of Endoconcha Sepiaes, 10 parts of Concha Arcaes, 30 parts of Fructus Amomis, 15 parts of Endothelium Corneum Gigeriae Galli, 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of the Rhizoma Pinelliaes.

The test example:

As follows through test that 296 patients with gastric disease (as following table) have been carried out taking medicine:

Nian Xingling is other	Below 40 years old	41-50 year	51-60 year	More than 61 years old	Add up to
Nian Xingling is other	Below 40 years old	41-50 year	51-60 year	More than 61 years old	Add up to	The male	38	39	48	33	158
The women	28	36	45	29	138	The male	38	39	48	33	158
The women	28	36	45	29	138	Add up to	66	75	93	62	296

Patients with gastric disease is very universal, and the male is more than the women, more than 2 years to 5 years 76, more than 5 years to 10 years 89, more than 10 years to 20 years 67, more than 20 years 35.

The gastropathy diagnostic criteria: so-called gastropathy is actually the general designation of many disease of stomach.They have similar symptom, as upper abdomen gastral cavilty portion discomfort, pain, after meal glutted, heating installation, return acid, even feel sick, vomiting or the like.Common clinically gastropathy have acute gastritis, chronic gastritis, gastric ulcer, duodenal ulcer, gastroduodenal complex ulcer, etc.

Acute simple gastritis is mainly due to pungents such as chemical substance such as strong tea, coffee, spirits, flavoring agent, or takes drug induced injury gastric mucosas such as salicylic acid salt medicine, sulphonamides, anticarcinogen, antibiotic, reserpine, Weishang gland sebum steroid and cause; Physical factor picture feed is supercool, cross and scald or roughage equivalent damage gastric mucosa brings out, and infected by microbes or bacteriotoxin cause.

Mostly acute corrosive gastritis is owing to commit suiside or wrongly take caustic such as strong acid and strong base causes.

Acute erosion (hemorrhagic) gastritis pilosity is born in the stress state that operation, burn, shock, wound, multiple organ failure, MOF etc. cause and is drunk or take non-steroidal drug and causes, accounts for about 20% in upper gastrointestinal hemorrhage.

Acute phlegmonous gastritis mainly is the purulent disease that is caused by bacterial infection coat of the stomach such as streptococcus, staphylococcus and escherichia coli, is referred to as areolar tissue inflammatory gastritis again.

Acute gastritis is the reversibility disease, can recover normal fully by treating.By appropriate treatment, a lot of acute gastritis patients can obtain effectively thoroughly rehabilitation fully, and that its characteristics are come is fast, go also soon.But if treat untimely or not thorough and improper diet, the long-standing words of the state of an illness will be converted into chronic gastritis.

Chronic gastritis is meant because the gastric mucosa chronic inflammatory disease due to a variety of causes changes.Be a kind of commonly encountered diseases the most and frequently-occurring disease.Characteristics are exactly that male's sickness rate is higher than the women, and sickness rate with age and in rising trend.After chronic gastritis its essence is that gastric epithelial suffers to damage repeatedly, because the special regeneration capacity of mucosa, so that mucosa reconstructed, and finally causes the atrophy of irreversible intrinsic gastric gland body, even disappearance.

The cause of disease that chronic gastritis forms generally believes it is the particularly chronic persistent infections of HP (helicobacter pylori) of pathogenic bacterium now; There is the acute gastritis of being exactly to be transformed again; The same with acute gastritis, physical factors such as overheated supercool too coarse food also are one of its causes of disease; Also has chemical factor, as strong tea, coffee, spirits, flavoring agent etc.; Take non-steroidal drug (as aspirin, indomethacin etc.) for a long time in a large number and can suppress the synthetic of gastric mucosa prostaglandin, destroy the mucosa barrier and cause; Nicotine during smoking in the Nicotiana tabacum L. had both influenced the blood circulation of gastric mucosa, can cause the sphincter of pylorus dysfunction again, caused bile reflux, thereby and various bile reflux all can be destroyed the generation that the mucosa barrier causes chronic gastritis; In addition, immune factor also is the reason that forms chronic gastritis.

The classification of chronic gastritis mainly contains chronic superficial gastritis and chronic atrophic gastritis, and both exist if having time simultaneously.Chronic superficial gastritis comprises simple type, three kinds of erosive type and bleeding types.Chronic atrophic gastritis is divided into two types: the A type, and pathological changes occurs in body of stomach, and parietal cell antibody is positive.Type B, pathological changes are mainly at gastric antrum, and parietal cell antibody is negative.China is comparatively common with the latter.

In addition, also having a kind of gastropathy of can not check obvious pathological changes, is exactly non-ucler dyspepsia.Non-ucler dyspepsia is a kind of functional gastropathy, also have small part to belong to slight organic disease, a lot of doctors of past are diagnosed as chronic gastritis, stomach neurosis, gastrointestinal tract autonomic nervous dysfunction, stomach functional dyspepsia, stomach spasm etc. with this disease.Sick authority investigates according to cri dernier cri, and the sickness rate of this disease in the crowd also is the common and frequently-occurring disease of stomach up to 10%.The patient has intermittence or persistence upper abdomen dull pain or idol has severe pain and discomfort, feels sick, vomiting, acid regurgitation, upper digestive tract symptom such as heartburn, but clinical examination such as gastroscope, upper digestive tract barium agent radiography and liver and gall pancreas B ultrasonic etc. can not find that other internal organs of harmonization of the stomach have organic disease or the slight pathological changes that causes these symptoms.The subjective symptom that is to say stomach is more, finds less or nothing but objective determination is positive.Its cause of disease should be relevant with gastric motor dysfunction, gastroduodenal mild inflammation, Nervous and Mental Factors.

Gastropathy clinical development standard:

1, be almost recovered: abdomen gastral cavilty portion discomfort, pain, after meal glutted, heating installation, return acid, even feel sick, transference cure such as vomiting.

2, produce effects: a series of sxs of patient obviously alleviate in three days.

3, effective: as to repair gastric mucosa

4, invalid: as not have improvement with each side function before the medication.

Administrated method: oral, graininess, every bag of 0.2g warm boiled water, each one bag of twice of every day.The 3-30 days course of treatment.

This medicine is satisfactory through clinical test results, and this medicine instant effect, effect are lasting, and toxic and side effects is little, and total effective rate can reach more than 98%.

The effect number	Be almost recovered	Produce effects	Effectively	Invalid
The effect number	Be almost recovered	Produce effects	Effectively	Invalid	Number	256	24	11	5
Account for total number of persons	86.5％	8.1％	3.7％	1.7％	Number	256	24	11	5

Claims

1. medicine for the treatment of gastropathy, it is made by effective ingredient and acceptable accessories, it is characterized in that effective ingredient wherein made by following weight crude drug: Endoconcha Sepiae 10-30 part, Concha Arcae 10-30 part, Fructus Amomi 5-30 part, Endothelium Corneum Gigeriae Galli 15-50 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-40 part, Rhizoma Pinelliae 15-20 part.

2. according to the medicine of the described treatment gastropathy of claim 1, it is characterized in that 10 parts of Endoconcha Sepiaes, 10 parts of Concha Arcaes, 30 parts of Fructus Amomis, 15 parts of Endothelium Corneum Gigeriae Galli, 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of the Rhizoma Pinelliaes.

3. according to the medicine of claim 1 or 2 described treatment gastropathy, it is characterized in that dosage form is tablet, capsule, granule, powder, pill.