CN101297945A - Medicament for treating pulmonary disease and tracheopathia and preparation method thereof - Google Patents
Medicament for treating pulmonary disease and tracheopathia and preparation method thereof Download PDFInfo
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- CN101297945A CN101297945A CNA2008100033531A CN200810003353A CN101297945A CN 101297945 A CN101297945 A CN 101297945A CN A2008100033531 A CNA2008100033531 A CN A2008100033531A CN 200810003353 A CN200810003353 A CN 200810003353A CN 101297945 A CN101297945 A CN 101297945A
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Abstract
The invention discloses a drug for curing pulmonary tracheopathia and a preparation method thereof, mainly comprising the preparation method of capsules and tablets by mainly selecting the Chinese herbal medicines of radix stemonae, stramonium, snakegourd fruit, fritillaria, Japanese ardisia, root of straight ladybell, ephedra herba, ophiopogon root and levant cotton root. The combination of all the Chinese herbal medicines can cause each medicine to produce cooperative effect so as to have the curative effects on cough relieving and sputum reducing with anti-asthma, acute and chronic bronchitis, asthma caused by tracheitis, whooping cough, cough with lung heat, throat sore and emphysema. In addition, the drug of the invention contains unique ingredients such as alkaloids, peltaphorin, bergenin I and bergenin II and triterpenoid saponin, etc., can effectively identify pulmonary tracheopathia factors and rapidly identify the positions of the pulmonary tracheopathia factors after entering the human body so as to divide, surround and eliminate the pulmonary tracheopathia factors. In addition, the capsules and the tablets of the drug of the invention are easy to be absorbed, with strong potency and long effective drug duration, can gradually recover damaged tissue and the normal functions of airways, has no influence on incretion, and also overcomes the defects that the traditional drug for curing the pulmonary tracheopathia has great toxic and side effects and short effective drug duration.
Description
Technical field:
The present invention relates to a kind of medicine for the treatment of the lung tracheopathy, relating in particular to a kind of is the medicine that primary raw material is produced with the Chinese herbal medicine, the invention still further relates to the compound method of this medicine.
Background information:
The sick full name of lung tracheitis is emphysema, acute/chronic bronchitis, obstructive emphysema is meant that eventually bronchioles fortune is not breathed heavily (alveolar bronchiole bubble pipe, alveolar sac and alveolar) the air flue elasticity attenuation, excessive expansion, inflation and lung capacity increase, and with the destruction of airway walls, because most of emphysematic patients are with chronic cough, the expectoration medical history, be difficult to chronic bronchitis well-separated, emphysema etc. with chronic bronchitis of airway obstruction feature are main performance, and can invade a plurality of systems whole body sexually transmitted disease (STD), regardless of the reason of its morbidity, all belong to lung tracheopathy category.At present, the method for the treatment of pneumonopathy and acute/chronic bronchitis disease both at home and abroad mainly contains western medicine, treatment by Chinese herbs etc.Its therapeutical effect of western medicine is fast, but lasting and toxic and side effects is big.And the treatment by Chinese herbs little but also lasting medicine of toxic and side effects not only.At present, the Chinese medicine for the treatment of lung, tracheitis disease both at home and abroad is of a great variety, and the different effect of filling a prescription is each has something to recommend him, but great majority bigger toxic and side effects is arranged, and medicine can not directly arrive the lesion curative effect be difficult to the performance.
Summary of the invention
The objective of the invention is to overcome the shortcoming of prior art, the natural drug that a kind of toxic and side effects is little, evident in efficacy, effect is lasting, prescription is unique and have quick-acting functions is provided, Chinese medicine capsule and tablet (breathing with cough, it is peaceful to see).The present invention uses Chinese medicine according to ancient medicine and theory of Chinese medical science, with natural Chinese medicinal herb, the Radix Stemonae, Flos Daturae, Fructus Trichosanthis, Bulbus Fritillariae Uninbracteatae, Herba Ardisiae Japonicae, Radix Adenophorae (Radix Glehniae), Herba Ephedrae, Radix Ophiopogonis, Radix Gossypii, being used in combination with these medicines, make the effect of each medicine produce synergism, thereby effectively treat the lung tracheopathy, drug component consumption of the present invention is groped to sum up through a large amount of practices and is drawn, and all has better curative effect in each component infra column weight amount ratio range.
Radix Stemonae 150-250 part Flos Daturae 20-40 part Bulbus Fritillariae Uninbracteatae 150-250 part
Fructus Trichosanthis 150-250 part Herba Ardisiae Japonicae 300-500 part Radix Adenophorae (Radix Glehniae) 100-200 part
Herba Ephedrae 80-200 part 200-300 Radix Ophiopogonis part Radix Gossypii 300-500 part
The optimum weight of medicine of the present invention by (part) proportioning is:
The Radix Stemonae 200, Flos Daturae 30, Fructus Trichosanthis 200, Bulbus Fritillariae Uninbracteatae 200, Herba Ardisiae Japonicae 400, Radix Adenophorae (Radix Glehniae) 150, Herba Ephedrae 140, Radix Ophiopogonis 250, Radix Gossypii 400.
The present invention can be made into capsule, tablet, and its compound method is:
1, capsule: take by weighing raw material according to above-mentioned component and weight proportion thereof, at first Flos Daturae is cooked, add Bulbus Fritillariae Uninbracteatae and pulverize into fine powder, add an amount of dextrin mix homogeneously then, making alkaloid is 0.52%, gives over to standby after configuring.Secondly the Radix Stemonae, Fructus Trichosanthis, Herba Ardisiae Japonicae, Radix Adenophorae (Radix Glehniae), Herba Ephedrae, Radix Ophiopogonis, Radix Gossypii, the every gram crude drug of mixing are added water and decoct twice for 10 milliliters, decoct twice decocting liquid of merging in two hours at every turn and concentrate.With medical filtration, and add Flos Daturae and Bulbus Fritillariae Uninbracteatae powder, stir and heated 15 minutes down at 70 °-80 ° degrees centigrade, take out the back in oven dry below 60 ° degrees centigrade, powder becomes fine powder to incapsulate then, and every capsules nearly weighs 0.2 gram, contains alkaloid 0.28-0.30 milligram.
2, tablet: take by weighing raw material according to above-mentioned component and weight proportion thereof.At first Flos Daturae is cooked, add Bulbus Fritillariae Uninbracteatae and pulverize into thin part, add an amount of dextrin mix homogeneously then, give over to after alkaloid 0.52% is configured standby.Secondly the Radix Stemonae, Fructus Trichosanthis, Herba Ardisiae Japonicae, Radix Adenophorae (Radix Glehniae), Herba Ephedrae, Radix Ophiopogonis, Radix Gossypii, the every gram crude drug of mixing being added water decocts twice for 10 milliliters.It is 1 that twice decocting liquid of each decoction merging in two hours, filtration are concentrated into proportion with medicine: 20-1: the extractum of 25 (room temperatures).Be added in the above-mentioned extractum grinding good Flos Daturae and Bulbus Fritillariae Uninbracteatae powder before, and add an amount of gelatinized corn starch and stir, make granule.Then in oven dry below 60 ° degrees centigrade.Add magnesium stearate then, magnesium stearate content is about weight ratio 0.3% and adds lubricant.At last, tabletting, sugar coating, each sheet nearly weigh 0.22 gram, alkaloid 0.28-0.30 milligram.
Through clinical use checking, the capsule and the tablet of the present invention's preparation all have following curative effect.
1. can relieving cough and resolving phlegm relieving asthma lung moistening, acute and chronic tracheitis, tracheitis, asthma, pertussis, cough due to lung-heat, laryngalgia, emphysema.
2. the present invention contains unique component, as alkaloid, arolisic acid B, Bergenin I and II, triterpene powder Saponin etc.Lung qi pipe cause of disease there be superpower distinguishing, after entering in the body, can distinguish rapidly that lung qi pipe factor position is cut apart the lung qi pipe factor and surround to eliminate remove that capsule of the present invention and tablet absorb easily, the efficacy of a drug is strong, lasting medicine, can progressively recover damaged tissues, recover the trachea normal function, endocrine is had no effect, it is big to overcome traditional lung tracheitis poisonous side effect of medicine, the shortcoming that effective drug duration is short.
3. instructions of taking of the present invention: for oral administration.Treating the course of treatment is three days to one courses of treatment of (seven days is a course of treatment) acute tracheitis palpus; Chronic tracheitis, tracheitis, asthma, pertussis must one to three courses of treatment, and cough due to lung-heat, laryngalgia, emphysema must two to five courses of treatment, and three times on the one, each two to three.
The specific embodiment:
Embodiment 1: capsule takes by weighing raw material according to following weight by (part) proportioning
The Radix Stemonae 200 Flos Daturae 30 Bulbus Fritillariae Uninbracteataes 200
Fructus Trichosanthis 200 Herba Ardisiae Japonicaes 400 Radix Adenophorae (Radix Glehniae) 150
Herba Ephedrae Radix Gossypii 400 140 Radix Ophiopogonis 250
Preparation method is as follows: take by weighing raw material according to above-mentioned weight, at first Flos Daturae is cooked, add Bulbus Fritillariae Uninbracteatae and pulverize into thin part, add an amount of dextrin mix homogeneously then, give over to after alkaloid 0.52% is configured standby; Secondly the Radix Stemonae, Fructus Trichosanthis, Herba Ardisiae Japonicae, Radix Adenophorae (Radix Glehniae), Herba Ephedrae, Radix Ophiopogonis, Radix Gossypii mixing, every gram crude drug being added water decocts twice for 10 milliliters.The each decoction two hours.Merge twice decocting liquid, with medicine filtering and concentrating at night, and adding Flos Daturae and Bulbus Fritillariae Uninbracteatae powder, stir and heated 15 minutes down at 70 °-80 ° degrees centigrade, take out the back in oven dry below 60 ° degrees centigrade, powder becomes fine powder to incapsulate then, every capsules nearly weighs 0.2 gram, contains alkaloid 0.28-0.30 milligram and gets final product.
Embodiment 2: tablet
Take by weighing raw material according to above-mentioned component and weight proportion thereof.At first Flos Daturae is cooked, add Bulbus Fritillariae Uninbracteatae and pulverize into thin part, add an amount of dextrin mix homogeneously then, make alkaloid 0.52%, give over to standby after configuring.Secondly the Radix Stemonae, Fructus Trichosanthis, Herba Ardisiae Japonicae, Radix Adenophorae (Radix Glehniae), Herba Ephedrae, Radix Ophiopogonis, Radix Gossypii are mixed every gram crude drug and add twice of 10 milliliters of decoction of water.Twice decocting liquid of each decoction merging in two hours, filtration, it is 1 that medicine is concentrated into proportion: 20-1: the extractum of 25 (room temperatures).Be added in the above-mentioned extractum grinding good Flos Daturae and Bulbus Fritillariae Uninbracteatae powder before, and add an amount of gelatinized corn starch and stir, make granule.Then in oven dry below 60 ° degrees centigrade.Add magnesium stearate then, magnesium stearate content is about weight ratio 0.3% and adds lubricant.At last, tabletting, sugar coating, each sheet nearly weigh 0.22 gram, and alkaloid 0.28-0.30 milligram gets final product.
Claims (3)
1, a kind of medicine (breathing with cough, it is peaceful to see) for the treatment of the lung tracheitis is characterized in that it mainly is the medicament of being made by (part) proportion raw material by following weight:
Radix Stemonae 150-250 part Flos Daturae 20-40 part Bulbus Fritillariae Uninbracteatae 150-250 part
Fructus Trichosanthis 150-250 part Herba Ardisiae Japonicae 300-500 part Radix Adenophorae (Radix Glehniae) 100-200 part
Herba Ephedrae 80-200 part 200-300 Radix Ophiopogonis part Radix Gossypii 300-500 part.
2, the medicine of treatment lung tracheopathy according to claim 1 is characterized in that wherein the weight of each raw material the best by (part) proportioning is:
The Radix Stemonae 200, Flos Daturae 30, Fructus Trichosanthis 200, Bulbus Fritillariae Uninbracteatae 200, Herba Ardisiae Japonicae 400, Radix Adenophorae (Radix Glehniae) 150, Herba Ephedrae 140, Radix Ophiopogonis 250, Radix Gossypii 400.
3, as claim: the medicine of 1.2 described treatment lung tracheitiies, can be made into tablet and capsule, preparation method is characterised in that:
1) tablet:
Take by weighing raw material according to above-mentioned component and weight proportion thereof. at first Flos Daturae is cooked, add Bulbus Fritillariae Uninbracteatae and pulverize into thin part, add an amount of dextrin mix homogeneously then, make alkaloid 0.52%, give over to standby after configuring.Secondly the Radix Stemonae, Fructus Trichosanthis, Herba Ardisiae Japonicae, Radix Adenophorae (Radix Glehniae), Herba Ephedrae, Radix Ophiopogonis, Radix Gossypii are mixed every gram crude drug and add twice of 10 milliliters of decoction of water.Twice decocting liquid of each decoction merging in two hours, filtration, it is 1 that medicine is concentrated into proportion: 20-1: the extractum of 25 (room temperatures).Be added in the above-mentioned extractum grinding good Flos Daturae and Bulbus Fritillariae Uninbracteatae powder before, and add an amount of gelatinized corn starch and stir, make a powder.Then in oven dry below 60 ° degrees centigrade.Add magnesium stearate then, magnesium stearate content is about weight ratio 0.3% and adds lubricant.At last, tabletting, sugar coating,, each sheet nearly weighs 0.22 gram, alkaloid 0.28-0.30 milligram.
2) capsule: take by weighing raw material by (part) proportioning according to following weight:
The Radix Stemonae 200, Flos Daturae 30, Fructus Trichosanthis 200, Bulbus Fritillariae Uninbracteatae 200, Herba Ardisiae Japonicae 400, Radix Adenophorae (Radix Glehniae) 150, Herba Ephedrae 140, Radix Ophiopogonis 250, Radix Gossypii 400.
Take by weighing raw material according to above-mentioned weight.At first Flos Daturae is cooked, add Bulbus Fritillariae Uninbracteatae and pulverize into fine powder, add an amount of dextrin mix homogeneously then, making alkaloid is 0.52%, gives over to standby after configuring.Secondly the Radix Stemonae, Fructus Trichosanthis, Herba Ardisiae Japonicae, Radix Adenophorae (Radix Glehniae), Herba Ephedrae, Radix Ophiopogonis, Radix Gossypii, the every gram crude drug of mixing are added water and decoct twice for 10 milliliters, decoct twice decocting liquid of merging in two hours at every turn.Medicine is filtered night, and add Flos Daturae and Bulbus Fritillariae Uninbracteatae powder, stir and heated 15 minutes down at 70 °-80 ° degrees centigrade, take out the back in oven dry below 60 ° degrees centigrade, powder becomes fine powder to incapsulate then, and every capsules nearly weighs 0.2 gram, contains alkaloid 0.28-0.30 milligram.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100033531A CN101297945A (en) | 2008-01-14 | 2008-01-14 | Medicament for treating pulmonary disease and tracheopathia and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100033531A CN101297945A (en) | 2008-01-14 | 2008-01-14 | Medicament for treating pulmonary disease and tracheopathia and preparation method thereof |
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| CN101297945A true CN101297945A (en) | 2008-11-05 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2008100033531A Pending CN101297945A (en) | 2008-01-14 | 2008-01-14 | Medicament for treating pulmonary disease and tracheopathia and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735844A (en) * | 2013-12-30 | 2014-04-23 | 彭声义 | Cough-relieving and sputum-reducing Chinese medicinal spray |
| CN105362860A (en) * | 2015-11-26 | 2016-03-02 | 李伟强 | Radix stemonae combination medicine for treating pertussis |
-
2008
- 2008-01-14 CN CNA2008100033531A patent/CN101297945A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735844A (en) * | 2013-12-30 | 2014-04-23 | 彭声义 | Cough-relieving and sputum-reducing Chinese medicinal spray |
| CN105362860A (en) * | 2015-11-26 | 2016-03-02 | 李伟强 | Radix stemonae combination medicine for treating pertussis |
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Addressee: Huang Minghua Document name: Notification to Make Rectification |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20081105 |