CN101292735A - Sorbitol buccal tablet composition and preparing method thereof - Google Patents
Sorbitol buccal tablet composition and preparing method thereof Download PDFInfo
- Publication number
- CN101292735A CN101292735A CNA2007101031736A CN200710103173A CN101292735A CN 101292735 A CN101292735 A CN 101292735A CN A2007101031736 A CNA2007101031736 A CN A2007101031736A CN 200710103173 A CN200710103173 A CN 200710103173A CN 101292735 A CN101292735 A CN 101292735A
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- sorbitol
- buccal tablet
- coating
- tablet
- adhesive
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Abstract
The invention relates to the composition of sopbitol buccal tablets and a production method thereof, which pertains to the field of foods, medicines and health care products. In addition, sopbitol coating technique can be applied to coating some medicines at will. The composition mainly comprises the sopbitol, binder, excipient and additive and is characterized in that the binder is one or the combination of sopbitol, acacia, sodium carboxymethylcellulose or starch; the sopbitol is adopted as a coating agent.
Description
Technical field
The invention belongs to food, medicine and field of health care products, relate to the composition and the manufacture method thereof of sorbitol buccal tablet.
Background technology
D-sorbite (the following sorbierite that also claims) is as sweetener, and sugariness is lower than sucrose (50-80% that is about sucrose); Because its heat of solution is big than sucrose, when sorbierite enters Orally dissolving, tangible refrigerant sense is arranged.
Sorbierite enters energy metabolism behind the human body, belongs to nutritive sweetener, then is absorbed but its metabolic pathway at first is slow diffusion, is oxidized to fructose, is utilized again, participates in the fructose metabolic pathway.The fructose metabolic process does not need insulin auxiliary, so the picked-up sorbierite to blood sugar and not influence of glucose in urine, can be used as the sweetener and the nutritional agents of diabetic product.
Sorbierite is difficult for not utilized by the streptococcus in the oral cavity, and the pH value in the oral cavity being risen slightly, so be a kind of anticariogenic sweet taste material by utilizations such as mould, yeast and lactic acid bacterias.
Sorbierite is ingested and is not decomposed by gastric enzyme behind the human body, in intestines the holdup time longer than glucose, so purging and intestine lubricating action is arranged, have defaecation or laxative function.
Traditional medicine sugar coated tablet is to adopt sucrose as coating agent, therefore becomes limiting factor for taking of sugar avoiding patient.And use composition of the present invention and method, and can produce the medicine that adopts the sorbierite dressing, eliminated taboo to sugar avoiding patient, enlarge medicine and be suitable for the crowd.
Summary of the invention
The objective of the invention is to: provide sorbitol buccal tablet to form and manufacture method, use mainly as food, health products.And the sorbierite packaging technique can be applied to the dressing of some medicine arbitrarily.
Sorbitol buccal tablet of the present invention, it mainly consists of: D-sorbite, adhesive, excipient and additive is characterized in that: adhesive is a kind of or its combination in sorbierite self, Arabic gum, sodium carboxymethylcellulose or the starch; The weight percentage of each component is: D-sorbite 30.0-99.0%, adhesive 0.1-10.0%, excipient 0.0-60.0%, flavoring essence 0.0-8.0%, food coloring 0.0-1.0%.The excipient that the present invention relates to comprises starch, pregelatinized starch etc.; Flavoring essence comprises the various edible essence that rules allow etc.; Food coloring comprises the various edible pigments that rules allow etc.
It is coating agent that the present invention adopts D-sorbite, and coating agent accounts for the 1.0-45.0% that gross mass is formed.
The specific embodiment
Can adopt the technology of direct tablet compressing to prepare plain sheet.
Also can adopt the preparation technology of wet method compressing tablet: primary raw material and ingredient powder are broken into fine powder and evenly mixing, add adhesive, through wet granulation, drying, whole grain adds additives such as flavoring essence, food coloring, and mix, compacting promptly gets plain sheet finished product in flakes then.
Plain sheet process dressing program by above-mentioned embodiment makes further obtains various coating tablet finished products.
Embodiment 1
Prescription is formed: D-sorbite 972mg, and flavoring essence (peppermint) 18mg, dolomol 10mg adds up to 1000mg.
After D-sorbite and flavoring essence, dolomol mixed, directly enter sheeting process promptly.
Embodiment 2
Prescription is formed: D-sorbite 916.98mg, and Arabic gum 25mg, excipient (pregelatinized starch) 20mg, flavoring essence (lemon) 15mg, food coloring (lemon yellow) 0.02mg, dolomol 1mg, citric acid 20mg adds up to 1000mg.
With the D-sorbite pulverizing and by 120 mesh sieves, Arabic gum is made adhesive with the pure water dissolving, drops in the wet mixing pelletizer successively then and granulates; The wet granular that makes is cooled to room temperature after 50 ℃ of dryings, by the whole grain of 40 mesh sieves; Material behind the whole grain is put into mixer, machines, and adds dolomol, flavoring essence, food coloring successively, after mixing, enters sheeting process, repressed in flakes promptly.
Embodiment 3
Plain sheet with embodiment 1, embodiment 2 make drops in the dressing machine, machines, and adds D-sorbite fine powder and gumwater gradually, till slice, thin piece increases weight to the weight of stipulating, promptly gets coating tablet.
Embodiment 4
Clearing heat and detoxicating plain label of a kind of medicine, the method for pressing embodiment 3 up to the increase weight weight of regulation or till surface smoothness meets the requirements of slice, thin piece, promptly gets clearing heat and detoxicating coating tablets sheet.
Claims (5)
1, sorbitol buccal tablet, it mainly consists of: D-sorbite, adhesive, excipient, additive and coating agent, the weight percentage of each component is: xylitol 30.0-99.0%, adhesive 0.1-10.0%, excipient 0.0-60.0%, coating agent 0.0-35.0%, flavoring essence 0.0-8.0%, food coloring 0.0-1.0%.
2, sorbitol buccal tablet according to claim 1 is characterized in that: adhesive is a kind of or its combination in sorbierite self, Arabic gum, sodium carboxymethylcellulose or the starch.
3, according to claim 1 and the described sorbitol buccal tablet of claim 2, can further make coating tablet, improve mouthfeel, hardness and outward appearance, it is characterized in that: coating agent is a D-sorbite.
4, sorbitol buccal tablet according to claim 1, process pulverizing, mixing, granulation, whole grain, tablet forming technique process make the method for plain sheet.
5, sorbitol buccal tablet according to claim 3, process art for coating process makes the technical method of coating tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101031736A CN101292735A (en) | 2007-04-26 | 2007-04-26 | Sorbitol buccal tablet composition and preparing method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101031736A CN101292735A (en) | 2007-04-26 | 2007-04-26 | Sorbitol buccal tablet composition and preparing method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101292735A true CN101292735A (en) | 2008-10-29 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101031736A Pending CN101292735A (en) | 2007-04-26 | 2007-04-26 | Sorbitol buccal tablet composition and preparing method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101292735A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101933567A (en) * | 2010-05-12 | 2011-01-05 | 谈小伦 | Golden pomelo sugar-free mint buccal tablet and preparation method thereof |
| CN110693842A (en) * | 2019-10-28 | 2020-01-17 | 浙江华康药业股份有限公司 | A kind of sorbitol tablet and its preparation method and application |
| CN113455577A (en) * | 2020-03-31 | 2021-10-01 | 仙乐健康科技股份有限公司 | Health food, functional food or special dietary food and preparation method thereof |
-
2007
- 2007-04-26 CN CNA2007101031736A patent/CN101292735A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101933567A (en) * | 2010-05-12 | 2011-01-05 | 谈小伦 | Golden pomelo sugar-free mint buccal tablet and preparation method thereof |
| CN101933567B (en) * | 2010-05-12 | 2013-08-28 | 谈小伦 | Golden pomelo sugar-free mint buccal tablet and preparation method thereof |
| CN110693842A (en) * | 2019-10-28 | 2020-01-17 | 浙江华康药业股份有限公司 | A kind of sorbitol tablet and its preparation method and application |
| CN113455577A (en) * | 2020-03-31 | 2021-10-01 | 仙乐健康科技股份有限公司 | Health food, functional food or special dietary food and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20081029 |