CN101284121A - Combination medicine for curing the hoary hair - Google Patents

Abstract

A Chinese medicinal composition for treating alopecia and leukotrichia contains thirty Chinese traditional medicines such as fineleaf schizonepeta herb, divaricate saposhnikovia root, ginger, rehmannia root, tree peony bark, red peony root, kuhseng, densefruit pittany root-bark, tuckahoe, oriental waterplantain tuber, belvedere fruit, danshen root, ginseng, safflower, jujube, fleece-flower root, mulberry fruit, angelica, drynaria, desertliving cistanche, prepared rehmannia root, solomonseal rhizome, eucommia, black sesame seed, black soyhean, chinese caterpillar fungus, forest frog oviduct, etc. Oral administration in combination with external application of the composition is adopted so that medicine factor directly acts on dermal layer of scalp for activating hair follicle cell regeneration, adjusting sebum secretion, improving scalp metabolism, supplementing nutrition required by hair, holding hair, blackening hair and caring hair.

Description

A kind of composition of medicine for the treatment of alopecia and white hair

Technical field:

The present invention relates to a kind of Chinese medicine preparation for the treatment of alopecia and white hair, belong to drug world.

Background technology:

Alopecia is a kind of common skin disease, can be divided into seborrheic alopecia (claiming seborrheic alopecia, male pattern alopecia again) alopecia areata, alopecia totalis etc.Common alopecia mostly is seborrheic alopecia (accounting for hair loss patient more than 95%) greatly, and its symptom causes the greasy humidity of hair, diseases such as the inflammation of also scratching where it itches with scalp sometimes for excessive the overflowing of patient's scalp fat.

Poliosis is one of old and feeble physiological change, and hair is bleached by black naturally gradually after the common people to 40 year old.Although at the different individualities position different with same individuality, morning and evening and speed that it bleaches are variant, compare with the ordinary people, do not bleach to the age hair, claim poliosis.

Alopecia, although the poliosis form of expression is different, but the reason that causes pathological changes has points of resemblance, the factor of existing congenital hereditary, posteriori factor is also arranged, existing physiological reason, pathologic reason is also arranged, and posteriori factor, both alopecias of causing of some pathologic factors, poliosis is the most common, its main cause, or because stress is big, psychic trauma, spiritual hypertonicity, mental work intensity is big, insomnia and dreamful sleep, or by various acute and chronic infectious disease, various dermatosiss cause, or the endocrine disturbance, reasons such as nutritional disorder all can cause alopecia, poliosis.

The traditional Chinese medical science is thought blood stored in the liver, hair is the sign of blood condition, the kidney generating marrow and dominating bone, its honor is being sent out, vim and vigour contain that then kidney qi is strong, kidney qi bone strengthening marrow is full of, and hair is black and glossy, and vim and vigour void is then a little less than the kidney qi, the vim and vigour unable to walk, it is damp and come off to send out then withered and yellow nothings, so think the formation and the deficiency of the liver and kindey of alopecia, poliosis, the vim and vigour weakness is relevant.Simultaneously, the people is subjected to internal injury caused by excess of seven emotions, depressed emotion, the impairment of the spleen of working with one's mind, to influence vim and vigour running smooth and cause qi depression to blood stasis, hair loses nutrition and comes off, the organism endocrine and the factors such as immunologic derangement imbalance, psychic trauma and hypertonicity, blood vessel and disturbance of blood circulation of this and modern medicine study, cause the trichotrophy obstacle and alopecia, poliosis identical of views, Clinical detection shows in recent years, and Endothelin (ET) content is apparently higher than the normal person among alopecia, the poliosis patients serum.Thisly can cause that local vascular is strongly sent out and contract spasm and cause the material that the stem blood supply reduces, can cause the hair exhaustion to come off or bleach.The hair blood flow detection confirms that also the hair loss patient scalp not only changes with medical science in a organized way, also has the resistance of blood flow height, and the blood flow total amount is few, effectively the abnormal phenomena of perfusion minimizing.

At present, aspect this class disease of treatment alopecia and white hair, use than the wide range of therapeutic method, or be local application, or be medication for oral administration.Local application, for example: 101 HAIR REGENERATING MEDICINE, this type of drug effect can cause the nutrition skin really in skin of head, promote local blood circulation, impel the hair that comes off to give birth to.But because this method is confined to take stopgap measures, and can not reach the purpose of effecting a permanent cure by conditioning viscera QI and blood function, so to caused by liver and kidney deficiency, the serious alopecia due to the deficiency of YIN-blood is difficult to play satisfactory therapeutic effects.And some oral medicine is difficult to receive that external used medicine directly acts on skin of head, promotes the ideal effect of local blood circulation.Therefore, the two all is difficult to play gratifying effect for the curative effect of treatment alopecia and white hair.

Summary of the invention:

At at present the treatment alopecia and white hair aspect existing defective, the present invention discloses a kind of composition of medicine for the treatment of alopecia and white hair, adopt the therapy of " for oral administration+external " double combination, make drug molecule directly act on the skin corium of scalp, the regeneration of activation hair follicle cell improves the scalp metabolism, regulates sebum secretion, replenish the hair desired nutritional, thereby reach the curative effect of hair strengthening, hair growth promoting, hair color.

Technical solution of the present invention is: a kind of pharmaceutical composition for the treatment of alopecia and white hair, form by following raw material of Chinese medicine.

Herba Schizonepetae 5-20 part, Radix Saposhnikoviae 5-20 part, Rhizoma Zingiberis Recens 5-20 part, Radix Rehmanniae 20-50 part, Cortex Moutan 10-30 part, Radix Paeoniae Rubra 10-40 part, Radix Sophorae Flavescentis 5-20 part, Cortex Dictamni 5-20 part, Poria 10-30 part, Rhizoma Alismatis 10-30 part, fructus kochiae 10-30 part, Cacumen Platycladi 10-40 part, Rhizoma Chuanxiong 10-20 part, Radix Salviae Miltiorrhizae 10-40 part, Flos Carthami 10-20 part, Radix Ginseng 10-20 part, Fructus Jujubae 10-20, Rhizoma Polygonati 15-45 part, Herba Cistanches 15-45 part, Cortex Eucommiae 10-40 part, Rhizoma Drynariae 20-50 part, Radix Rehmanniae Preparata 20-50 part, Radix Polygoni Multiflori 15-45 part, Radix Angelicae Sinensis 10-40 part, Fructus Lycii 5-20 part, Fructus Mori 10-40 part, Fructus Ligustri Lucidi 5-20 part, Herba Ecliptae 20-50 part, Fructus Crataegi 15-45 part, Radix Et Rhizoma Rhei 10-30 part, Semen Sesami Nigrum 10-30 part, Semen sojae atricolor 10-30 part, Cordyceps 5-20 part, oviductus ranae 5-20 part.

The weight ratio that said medicine is formed is preferably: (unit: gram)

Herba Schizonepetae 10, Radix Saposhnikoviae 10, Rhizoma Zingiberis Recens 10, the Radix Rehmanniae 30, Cortex Moutan 10, Radix Paeoniae Rubra 15, Radix Sophorae Flavescentis 10, Cortex Dictamni 10, Poria 12, Rhizoma Alismatis 12, fructus kochiae 12, Cacumen Platycladi 15, Rhizoma Chuanxiong 10, Radix Salviae Miltiorrhizae 15, Flos Carthami 10, Radix Ginseng 10,10 in Fructus Jujubae, Rhizoma Polygonati 20, Herba Cistanches 20, the Cortex Eucommiae 15, Rhizoma Drynariae 20, Radix Rehmanniae Preparata 30, Radix Polygoni Multiflori 20, Radix Angelicae Sinensis 15, Fructus Lycii 10, Fructus Mori 15, Fructus Ligustri Lucidi 10, Herba Ecliptae 30, Fructus Crataegi 15, Radix Et Rhizoma Rhei 12, Semen Sesami Nigrum 25, Semen sojae atricolor 25, Cordyceps 15, oviductus ranae 15.

In the pharmaceutical composition of the present invention, the relieving the exterior syndrome with drugs of pungent in flavor and warm in nature medicine has: Herba Schizonepetae, Radix Saposhnikoviae, Rhizoma Zingiberis Recens etc.; The clearing away heat,cooling blood and removing toxin medicine has: the Radix Rehmanniae, Cortex Moutan, Radix Paeoniae Rubra, Radix Sophorae Flavescentis, Cortex Dictamni etc.; The promoting diuresis to eliminate damp pathogen medicine has: Poria, Rhizoma Alismatis, fructus kochiae etc., and heat clearing away blood stasis dispelling medicine has: Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Flos Carthami; QI invigorating, the medicine of enriching blood have: Radix Ginseng, Fructus Jujubae, Rhizoma Polygonati, Herba Cistanches, the Cortex Eucommiae, Rhizoma Drynariae, Radix Rehmanniae Preparata, Radix Polygoni Multiflori, Radix Angelicae Sinensis, Fructus Lycii, Fructus Mori, Fructus Ligustri Lucidi, Herba Ecliptae, Fructus Crataegi etc.; Cathartic drug: Radix Et Rhizoma Rhei etc., the medicine of invigorating the liver and kidney, the liver benefiting spleen has: Semen sojae atricolor, Semen Sesami Nigrum, Cordyceps, Rana nigromaculata wet goods.

The used material medicine of the present invention all can be bought from common pharmacy and obtain, and its specification meets national medical standard.

The specific embodiment

Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never limit protection scope of the present invention.

Take by weighing each medicine (unit: gram): Herba Schizonepetae 10, Radix Saposhnikoviae 10, Rhizoma Zingiberis Recens 10, the Radix Rehmanniae 30 by following weight, Cortex Moutan 10, Radix Paeoniae Rubra 15, Radix Sophorae Flavescentis 10, Cortex Dictamni 10, Poria 12, Rhizoma Alismatis 12, fructus kochiae 12, Cacumen Platycladi 15, Rhizoma Chuanxiong 10, Radix Salviae Miltiorrhizae 15, Flos Carthami 10, Radix Ginseng 10,10 in Fructus Jujubae, Rhizoma Polygonati 20, Herba Cistanches 20, the Cortex Eucommiae 15, Rhizoma Drynariae 20, Radix Rehmanniae Preparata 30, Radix Polygoni Multiflori 20, Radix Angelicae Sinensis 15, Fructus Lycii 10, Fructus Mori 15, Fructus Ligustri Lucidi 10, Herba Ecliptae 30, Fructus Crataegi 15, Radix Et Rhizoma Rhei 12, Semen Sesami Nigrum 20, Semen sojae atricolor 20, Cordyceps 15, oviductus ranae 10.

Processing method is: with above-mentioned raw material of Chinese medicine decocting, leaching liquid 500-1000 milliliter, get its 1/2nd daily in morning and evening twice oral, / 2nd filtrates are dipped in taking liquid with cotton balls every day at twice in addition, put on the skin repeatedly and smear alopecia place, poliosis place, respectively once, 30 days is a course of treatment sooner or later.

The inventor passes through clinical research for many years, in conjunction with dialectical with debate the principle that disease combines, implement the method for " for oral administration+external " treating both the principal and secondary aspects of a disease, summary is with nourishing the liver and kidney, benefiting QI for strengthening the superficies, yin nourishing removing heat from blood, depressed liver-energy dispersing and QI regulating, astringent or styptic treatment for spontaneous sweating collateral dredging is the invention drug regimen of the main rule of treatment, tries out in clinical, has obtained comparatively ideal therapeutic effect for alopecia, poliosis.

The inventor with Drug therapy alopecia and white hair of the present invention, clinical cure 3000 many cases, allows the patient of alopecia bear new hair through 30 years of researches and exploration, and the poliosis patient becomes hair color.The inventor treats observation to 1012 routine patients wherein, has proved that medicine of the present invention all has original curative effect to all kinds of alopecia and white hairs.Curative effect is summarized as follows table:

The sick kind	Case load	Cure	Produce effects	Effectively	Invalid	Effective percentage
							Alopecia	526	323	135	60	24	95.2％
Poliosis	486	313	106	52	26	94.7％

Through any untoward reaction is not seen in 1012 routine patient's clinical observations, illustrate that pharmaceutical composition of the present invention is the safe and effective medicine of a kind of treatment alopecia and white hair.

Clinical case: 1, grandson XX government functionary, people from Jieshou City, the man, 38 years old now, alopecia was serious, with other drug treatment 1 year, grew the sub-fraction fine, soft fur and sent out, and all came off again at last, and I lose the confidence to treatment.Through repeatedly consulting, reporting the psychology that has a try, treat several times in here in May, 2006, I feel that positive effect is arranged.Bear sturdy hairs after 2 weeks and come, adhered to treating 3 months, originally acomia all over the face he has been a black hair now.

2, poplar XX, woman, student, people from Jieshou City, 17 years old now, juvenile poliosis, because of many families fail to respond to any medical treatment, thought is sorely distressed, give she of the reading of going to school, stress is very heavy, in May, 2006 here treatment after one month poliosis disappear, recovered original juvenile black hair.

3, poplar XX, woman, people from Jieshou City, 18 years old now, to do manual work in the Dongguan, Guangzhou, alopecia is serious, can't work down, go to how home hospitalize invalid, thought is very worried, stress is very big, comes back to hometown afterwards that it is hopeless to hurry back and forth everywhere, after run into the people who cures and introduce, in in July, 2006 here diagnoses and treatment, one week is with regard to anti-avulsion, and treatment recovery from illness after month is got back to Guangzhou again and done manual work and gone.

4, old XX, the man, people from Shenqiu County, Henan 27 years old now, does manual work in Shanghai.Because operating pressure is big, the alopecia especially severe can't be worked down, hurries back and forth and each tame hospital and hair therapy unit, and fruit does not all take effect.After coming back to hometown, the people through treating introduces, and comes the here diagnosis, in August, 2006 begin treatment.One week treatment anti-avulsion bears new hair after two weeks, a wheat harvesting period has just recovered normally to maintain again one month, recovers well to get back to work position, Shanghai again fully and has got on.

Claims (2)

1, a kind of pharmaceutical composition for the treatment of alopecia and white hair is characterized in that, is made up of following raw material of Chinese medicine:

Herba Schizonepetae 5-20 part, Radix Saposhnikoviae 5-20 part, Rhizoma Zingiberis Recens 5-20 part, Radix Rehmanniae 20-50 part, Cortex Moutan 10-30 part, Radix Paeoniae Rubra 10-40 part, Radix Sophorae Flavescentis 5-20 part, Cortex Dictamni 5-20 part, Poria 10-30 part, Rhizoma Alismatis 10-30 part, fructus kochiae 10-30 part, Cacumen Platycladi 10-40 part, Rhizoma Chuanxiong 10-20 part, Radix Salviae Miltiorrhizae 10-40 part, Flos Carthami 10-20 part, Radix Ginseng 10-20 part, Fructus Jujubae 10-20, Rhizoma Polygonati 15-45 part, Herba Cistanches 15-45 part, Cortex Eucommiae 10-40 part, Rhizoma Drynariae 20-50 part, Radix Rehmanniae Preparata 20-50 part, Radix Polygoni Multiflori 15-45 part, Radix Angelicae Sinensis 10-40 part, Fructus Lycii 5-20 part, Fructus Mori 10-40 part, Fructus Ligustri Lucidi 5-20 part, Herba Ecliptae 20-50 part, Fructus Crataegi 15-45 part, Radix Et Rhizoma Rhei 10-30 part, Semen Sesami Nigrum 10-30 part, Semen sojae atricolor 10-30 part, Cordyceps 5-20 part, oviductus ranae 5-20 part.

2, according to claim 1, a kind of pharmaceutical composition for the treatment of alopecia and white hair is made of one day dosage (unit: gram) following raw material of Chinese medicine.

Herba Schizonepetae 10, Radix Saposhnikoviae 10, Rhizoma Zingiberis Recens 10, the Radix Rehmanniae 30, Cortex Moutan 10, Radix Paeoniae Rubra 15, Radix Sophorae Flavescentis 10, Cortex Dictamni 10, Poria 12, Rhizoma Alismatis 12, fructus kochiae 12, Cacumen Platycladi 15, Rhizoma Chuanxiong 10, Radix Salviae Miltiorrhizae 15, Flos Carthami 10, Radix Ginseng 10,10 in Fructus Jujubae, Rhizoma Polygonati 20, Herba Cistanches 20, the Cortex Eucommiae 15, Rhizoma Drynariae 20, Radix Rehmanniae Preparata 30, Radix Polygoni Multiflori 20, Radix Angelicae Sinensis 15, Fructus Lycii 10, Fructus Mori 15, Fructus Ligustri Lucidi 10, Herba Ecliptae 30, Fructus Crataegi 15, Radix Et Rhizoma Rhei 12, Semen Sesami Nigrum 25, Semen sojae atricolor 25, Cordyceps 15, oviductus ranae 15.