CN101284088A - Chinese medicine preparation for effectively relieving pain caused by acute and chronic soft tissue injury - Google Patents
Chinese medicine preparation for effectively relieving pain caused by acute and chronic soft tissue injury Download PDFInfo
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- CN101284088A CN101284088A CNA200810058484XA CN200810058484A CN101284088A CN 101284088 A CN101284088 A CN 101284088A CN A200810058484X A CNA200810058484X A CN A200810058484XA CN 200810058484 A CN200810058484 A CN 200810058484A CN 101284088 A CN101284088 A CN 101284088A
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Abstract
A Chinese traditional medicinal preparation for effectively relieving pain due to acute/chronic soft tissue injury contains sticktight, kassord tree fruit, rhubarb, notoginseng, Chinese Paris rhizome, etc. The preparation has forms such as ointment, external gel, etc., and is effective in promoting blood circulation and eliminating blood stasis, clearing away heat and toxic material, relieving spasm and pain and subsiding swelling and promoting tissue regeneration, and can be used for treating relieving pain due to acute/chronic soft tissue injury with a clinical total effective rate of 85%. The preparation has no toxic and side effect in clinical observation, and is safe.
Description
Technical field:
The present invention relates to a kind of Chinese medicine preparation, especially treat pain caused preparation of acute and chronic soft tissue injury and preparation method thereof, its dosage form is dosage forms such as ointment, external-use gel, belongs to field of traditional Chinese.
The pain caused medicine of the acute and chronic soft tissue injury of a kind of effective alleviation is the Chinese patent medicine of feedstock production with Chinese herbal medicine such as Herba Bidentis Bipinnatae, Cassia siamea, Radix Et Rhizoma Rhei, Radix Notoginseng, Rhizoma Paridis specifically, the invention still further relates to the preparation technology of this medicine.
Herba Bidentis Bipinnatae: Compositae, Bidens bipinnata belongs to, and formal name used at school: Bidens plants name: bipinata.
Cassia siamea: Caesalpiniaceae, Cassia, formal name used at school: Cassia plants name: seamia.
Background of invention:
The traditional Chinese medical science thinks that acute and chronic soft tissue injury morbidity is (cause of disease+disease position) ten symptoms.The cause of disease, sick position are that body is subjected to exopathogen or accidental injury invasion and attack suddenly and causes qi depression to blood stasis, stagnation of QI and blood may bring about pain.Common sympton such as damage location pain, ecchymosis, limitation of activity etc.Oneself has unguentum, film former, spray agent, gauze agent, aerosol etc. to alleviate the pain caused external treatment medicament appearance of acute and chronic soft tissue injury at present, but curative effect is undesirable in application.
Goal of the invention:
The object of the present invention is to provide a kind of medicine with blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, anti-inflammatory analgesic, detumescence and promoting granulation effect, and make unformed wound-surface cover, reach preserve moisture, skin moistening, muscles and tendons relaxing to alleviate pain, porous improve the lesions position blood circulation to subcutaneous tissue inside and intercellular substance, diminish inflammation, rapidly pain relieving is safeguarded the microenvironment of cells survival to promote the damaged tissue of Regeneration and Repair simultaneously.
Another object of the present invention provides the preparation method of alleviating the pain caused therapeutic agent of acute and chronic soft tissue injury.
Summary of the invention:
Solution of the present invention is based on motherland's medical science to pain caused pathogenetic understanding of acute and chronic soft tissue injury and Therapeutic Principle, achieve with reference to modern pharmacological research, from motherland's medicine and pharmacology treasure-house, filter out the natural plant of blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, anti-inflammatory analgesic, detumescence and promoting granulation, according to Chinese medicine and pharmacy monarch, minister, assistant, make compatibility theory, take efficacy of drugs into account and cure mainly, return effect characteristics prescription through, four natures and five flavors of drug and medicine itself.Medicine of the present invention is made with following each composition combination:
Herba Bidentis Bipinnatae 100 gram Cassia siamea 150 gram Radix Et Rhizoma Rhei 50 gram Radix Notoginseng the 25th grammes per square metre buildings 30 grams
The prescription compatibility is according to being: the lightly seasoned property of Herba Bidentis Bipinnatae is flat nontoxic, goes into lung, spleen, stomach, large intestine channel, the heat-clearing and toxic substances removing dissipating blood stasis; Cassia siamea, bitter, cold, go into the heart, spleen, liver, kidney, gallbladder, large intestine channel has heat-clearing and toxic substances removing, detumescence and promoting granulation, the merit of relieving spasm to stop pain, two medicines share and are principal agent; Radix Et Rhizoma Rhei, bitter, cold, go into lung, gallbladder, liver, stomach, large intestine channel, Rhizoma Paridis, bitter, tremble with fear, go into kidney, wing skin, large intestine channel, two medicine heat-clearing and toxic substances removing, the pathogenic fire purging remuval of damp and hot is ministerial drug; Radix Notoginseng, blood circulation promoting and blood stasis dispelling are adjuvant drug.Full side supplements and complements each other, and compatibility is rigorous, and all medicines share, and medicine reaches disease institute, so can prove effective.
Advantage of the present invention:
The present invention is the pain caused ointment formulation of the exploitation acute and chronic soft tissue injury of a kind of effective alleviation.Said preparation has effects such as blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, anti-inflammatory analgesic, detumescence and promoting granulation.Said preparation is with low cost, makes simply, and implementation and operation is convenient, can bring bigger social benefit, economic benefit.
Preparation technology of the present invention:
Above-mentioned raw materials is mixed in proportion, pulverized 40 mesh sieves, put into 10 times of water and boiled 50-60 minute, solution is leached.This method of pressing three times repeatedly merges filtrate, filters repeatedly three times, and filtrate was left standstill 48 hours, and supernatant is separated, and refilters.Filtrate is dried to the extractum of 5% water content.This extractum is cooperated with different Ji Quality in 3% ratio, can produce dosage forms such as ointment, external-use gel, after radiation sterilization, pack.
Clinical efficacy:
The observation of curative effect that 60 routine acute ankles, elbow joint are sprained:
Male 33 examples in 50 examples of treatment, women 27 examples; Age 18-52 year, average 36.8 years old; The course of disease: 1-4 day, day person 25 examples wherein＜1,2-3 days person's 30 examples, 4 days person's 5 examples.The patient all has ankle, ancon trauma history, shows as local pain, tenderness, even swelling is livid purple, limitation of activity.All patients all get rid of ankle, ancon fracture and dislocation through the X ray examination.
Use said preparation to be adjusted to pasty state, evenly spread on the affected part, once a day, logotype 6th was a course of treatment.
Effect criterion: recovery from illness: symptom complete obiterations such as ankle, elbow joint pain, activity recover operate as normal freely; Take a turn for the better: ankle, elbow joint pain are alleviated substantially, but still have mild pain and local tenderness when movable; Invalid: after treating 6 days, symptom and signs such as ankle, elbow joint pain do not have obvious improvement.
In therapeutic process from finding no any side effect.
The different course of disease therapeutic effect of table 1 (example)
The different course of disease therapeutic effect of table 1 (example)
Discuss
Products characteristics: the pure natural plant preparation, have no side effect, instant effect, curative effect height, no pain, safe and reliable.
The product effect: it has effects such as blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, anti-inflammatory analgesic, detumescence and promoting granulation.
This product is by being coated with target administration, percutaneous controlled-release outside the affected part, penetrate with absorbability extremely strongly, analgesic effect is fast and lasting, dredging the meridian, regulate neural and the enhancing local blood circulation, the reparation of vigorous metabolism and meridians, thus it is pain caused effectively to remove acute and chronic soft tissue injury.
Claims (2)
1, the pain caused Chinese medicine preparation of the acute and chronic soft tissue injury of a kind of effective alleviation is characterized in that described Chinese medicine preparation is to be extracted by following flavour of a drug to be prepared from: Herba Bidentis Bipinnatae 100 gram Cassia siamea 150 gram Radix Et Rhizoma Rhei 50 gram Radix Notoginseng the 25th grammes per square metre buildings 30 grams
2, the preparation method of the described Chinese medicine preparation of claim 1 is characterized in that the technological process of described preparation is: above-mentioned raw materials is mixed in proportion, pulverized 40 mesh sieves, put into 10 times of water and boiled 50-60 minute, solution is leached.This method of pressing three times repeatedly merges filtrate, filters repeatedly three times, and filtrate was left standstill 48 hours, and supernatant is separated, and refilters.Filtrate is dried to the extractum of 5% water content.This extractum is cooperated with different Ji Quality in 3% ratio, can produce dosage forms such as ointment, external-use gel, be Chinese medicine preparation of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA200810058484XA CN101284088A (en) | 2008-06-03 | 2008-06-03 | Chinese medicine preparation for effectively relieving pain caused by acute and chronic soft tissue injury |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA200810058484XA CN101284088A (en) | 2008-06-03 | 2008-06-03 | Chinese medicine preparation for effectively relieving pain caused by acute and chronic soft tissue injury |
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| Publication Number | Publication Date |
|---|---|
| CN101284088A true CN101284088A (en) | 2008-10-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA200810058484XA Pending CN101284088A (en) | 2008-06-03 | 2008-06-03 | Chinese medicine preparation for effectively relieving pain caused by acute and chronic soft tissue injury |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012091685A1 (en) * | 2010-12-30 | 2012-07-05 | Anandechakunkorn Siridechpong | Thai herb modified traditional drugs |
-
2008
- 2008-06-03 CN CNA200810058484XA patent/CN101284088A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012091685A1 (en) * | 2010-12-30 | 2012-07-05 | Anandechakunkorn Siridechpong | Thai herb modified traditional drugs |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20081015 |