CN101283739A - Composite additive agent for preventing the cobia fatty liver - Google Patents
Composite additive agent for preventing the cobia fatty liver Download PDFInfo
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- CN101283739A CN101283739A CNA2008100285975A CN200810028597A CN101283739A CN 101283739 A CN101283739 A CN 101283739A CN A2008100285975 A CNA2008100285975 A CN A2008100285975A CN 200810028597 A CN200810028597 A CN 200810028597A CN 101283739 A CN101283739 A CN 101283739A
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- fatty liver
- cobia
- carnitine
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- liver
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
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- Feed For Specific Animals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to a feed additive and more particularly a feed additive for preventing fatty liver in prodigal son (Rachycentron canadum). The compound additive for preventing fatty liver in prodigal son contains the flowing ingredients in weight proportions: L-carnitine 30-60, inositol 5-20, vitamin E 5-15, Artemisia 20-30, indigowoad root 8-12 and Astragalus membranaceus 6-15. The invention has the advantages that: (1) the hepatic indexes (HIS) of prodigal son are significantly reduced, the ability of fat transport in the liver is improved, the incidence of diseases is reduced, and the survival rate is increase; (2) the feed additive accounts for 0.15-0.3% of the feed; (3) the feed additive has both pharmaceutical and nutritious effects and helps prevent and treat diseases and improve reproductive ability; and (4) the raw materials of the compounded additive are easily accessible and the production process is simple.
Description
[technical field]
The present invention relates to a kind of feed addictive, relate in particular to a kind of feed addictive that is used to prevent cobia fatty liver.
[background technology]
Cobio (Rachycentron canadum) belongs to Perciformes, and cobio belongs to, popular name Cobia, sea otter fish, it is famous and precious seafood fish, also be the important marine culture and stock enhancement fish species in area such as present China Guangdong, Hainan, market is very wide, and economic worth is very high.The exploitation of the young postlarva of cobio and adult fish nutritional need and mixed feed has at present begun to carry out, as Chinese patent CN03112115.2 and CN200410026485.8 etc.But, along with cobio aquaculture flourish in China, the particularly development of high density intensive culture, being on the rise of cobia fatty liver has a strong impact on the survival rate and the speed of growth of cobio, becomes the major obstacle that development is cultured in restriction.Some researchs have begun to carry out the screening of cobio lipotropic factor, document sees reference: Zhou Meng, Deng. add the influence of phosphatide oil, choline, L-carnitine in the feed to cobio growth and tissue fat content. feed industry .2007 (10) and Wang Jiteng, wait and add .2 fat level under that carnitine is grown to cobio and the influence of body composition. Oceanography Institute Of Zhejiang's journal (natural science edition) .2007 (2).Therefore, develop a kind of AFL compound additive of commercialization,, promote the cobio healthy aquaculture to have crucial meaning improving the survival rate of cobio.
[summary of the invention]
The present invention aims to provide a kind of occurrence frequency that can reduce cobia fatty liver, reduces the accumulation of cobio liver fat, thus the compound additive of prevention cobia fatty liver.
A kind of compound additive that prevents cobia fatty liver of the present invention, its composition and mass ratio are:
L-carnitine 30-60, inositol 5-20, VE 5-15, oriental wormwood 20-30, Radix Isatidis 8-12, Radix Astragali 6-15.
Above-mentioned composition after pulverizing mixed by weight percentage get final product.When throwing something and feeding, its addition is the 0.15-0.3% of feeding quality.
The present invention uses multivitamin and Chinese herbal medicine to carry out reasonable compatibility first; can strengthen cobio hepatic metabolism function; the enhance hepatocyte detoxification ability; quicken hepatocellular regeneration; can get rid of bacterium rapidly; noxious materials such as toxin that virus produces and food interior metabolism product have good protective effect and repair to hepatic injury.Liver diseases such as liver enlargement, atrophy, erosion, hepatitis, fatty liver are all had fabulous prevention effect, and to the acute and chronic drug poisoning, the bait that goes mouldy is poisoned and is recovered all to have good adjuvant treatment effect after being ill.
The present invention has the following advantages: (1) obviously reduces cobio liver index (HSI), improves the ability of cobio liver transhipment fat, reduces the generation of disease, improves survival rate; (2) addition only is 0.15-0.3% in the feed; (3) have medicine and nutrition double action, can prevent and cure diseases, can improve production performance again; (4) raw materials enjoy stable sources of this compound additive, production technology are simple.
[specific embodiment]
Embodiment one
Take by weighing L-carnitine 500kg respectively, inositol 100kg, VE 50kg, oriental wormwood 200kg, Radix Isatidis 80kg, Radix Astragali 70kg, and pulverize the back respectively and cross to mix behind 100 mesh sieves and get final product.
Embodiment two
Take by weighing L-carnitine 330kg respectively, inositol 150kg, VE 50kg, oriental wormwood 200kg, Radix Isatidis 120kg, Radix Astragali 150kg, and pulverize the back respectively and cross to mix behind 100 mesh sieves and get final product.
Embodiment three
Take by weighing L-carnitine 300kg respectively, inositol 50kg, VE 150kg, oriental wormwood 300kg, Radix Isatidis 100kg, Radix Astragali 100kg, and pulverize the back respectively and cross to mix behind 100 mesh sieves and get final product.
Embodiment four
Culture the cobio juvenile fish that initial body weight is about 5.5g, content of triglyceride in its average growth rate of observation, become rate, liver index (HIS), hepatic fat content and the blood plasma after 100 days.Wherein added the compound additive of prevention cobia fatty liver of the present invention in the normal diet of experimental group, addition is 0.15% of a normal diet quality.The control group normal diet of only throwing something and feeding.The results are shown in Table 1.
Table 1
| Rate of body weight gain | Survival rate | Liver body ratio index (HSI) | Hepatic fat content | Content of triglyceride in the blood plasma | |
| Experimental group | 4453.0％ | 87％ | 2.08％ | 11.3％ | 1.97mmol/l |
| Control group | 3578.0％ | 68％ | 2.45％ | 14.2％ | 2.85mmol/l |
The result shows that compound additive of the present invention can obviously improve rate of body weight gain and the survival rate of cobio, reduces content of triglyceride in liver body ratio index (HSI), hepatic fat content and the blood plasma, the fatty liver of effectively preventing cobio.
Embodiment five
Culture the cobio that initial body weight is about 10.0g, cholesterol level and gpt level in 63 its average growth rates of back observation, become rate, the blood plasma.Wherein added the compound additive of prevention cobia fatty liver of the present invention in the normal diet of experimental group, addition is 0.3% of a normal diet quality.The control group normal diet of only throwing something and feeding.The results are shown in Table 2.
Table 2
| Rate of body weight gain | Survival rate | Cholesterol level in the blood plasma | Gpt level | |
| Experimental group | 605.0％ | 96％ | 3.30mmol/l | 110IU/L |
| Control group | 462.0％ | 74％ | 3.98mmol/l | 125IU/L |
The result shows that compound additive of the present invention can obviously improve rate of body weight gain and survival rate, reduces cholesterol level in the blood plasma, reduces gpt level.
Claims (4)
1, a kind of compound additive that prevents cobia fatty liver is characterized in that composition and mass ratio are:
L-carnitine 30-60, inositol 5-20, VE 5-15, oriental wormwood 20-30, Radix Isatidis 8-12, Radix Astragali 6-15.
2, complex immunity strengthening agent for crabeater young fish as claimed in claim 1 is characterized in that composition and mass ratio are:
L-carnitine 50, inositol 10, VE 5, oriental wormwood 20, Radix Isatidis 8, the Radix Astragali 7.
3, complex immunity strengthening agent for crabeater young fish as claimed in claim 1 is characterized in that composition and mass ratio are:
L-carnitine 33, inositol 15, VE 5, oriental wormwood 20, Radix Isatidis 12, the Radix Astragali 15.
4, complex immunity strengthening agent for crabeater young fish as claimed in claim 1 is characterized in that composition and mass ratio are:
L-carnitine 30, inositol 5, VE 15, oriental wormwood 30, Radix Isatidis 10, the Radix Astragali 10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100285975A CN101283739B (en) | 2008-06-06 | 2008-06-06 | Composite additive agent for preventing the cobia fatty liver |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100285975A CN101283739B (en) | 2008-06-06 | 2008-06-06 | Composite additive agent for preventing the cobia fatty liver |
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| Publication Number | Publication Date |
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| CN101283739A true CN101283739A (en) | 2008-10-15 |
| CN101283739B CN101283739B (en) | 2011-01-19 |
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| CN2008100285975A Active CN101283739B (en) | 2008-06-06 | 2008-06-06 | Composite additive agent for preventing the cobia fatty liver |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101978855A (en) * | 2010-10-15 | 2011-02-23 | 湖北海大饲料有限公司 | Artificial compound feed for resisting fatty liver of grass carp |
| CN102210411A (en) * | 2011-06-08 | 2011-10-12 | 广东恒兴饲料实业股份有限公司 | Compound feed capable of improving fatty liver and body colour of marine fish and preparation method thereof |
| CN102283332A (en) * | 2011-08-25 | 2011-12-21 | 北京大北农科技集团股份有限公司 | Feed additive and premix compound for promoting grass carp liver and immunologic function repair |
| CN103989023A (en) * | 2014-06-09 | 2014-08-20 | 中山大学 | Special anti-fatty liver additive for hybrid snakehead and preparation method thereof |
| CN107242162A (en) * | 2017-06-07 | 2017-10-13 | 珠海市斗门区河口渔业研究所 | A kind of cultural method for preventing and treating jewfish fatty liver |
| CN107455613A (en) * | 2017-09-11 | 2017-12-12 | 浙江海洋大学 | A kind of feed that can improve large yellow croaker fatty liver and preparation method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1218706C (en) * | 2001-05-20 | 2005-09-14 | 许喜训 | Hepatitis B treaitng pill |
| CN1230091C (en) * | 2004-04-22 | 2005-12-07 | 山西省农业高新技术园区管理服务中心 | Vitamin premixing material for salmo irideus fish nursing period and its preparing method |
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2008
- 2008-06-06 CN CN2008100285975A patent/CN101283739B/en active Active
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101978855A (en) * | 2010-10-15 | 2011-02-23 | 湖北海大饲料有限公司 | Artificial compound feed for resisting fatty liver of grass carp |
| CN101978855B (en) * | 2010-10-15 | 2012-05-23 | 湖北海大饲料有限公司 | Artificial compound feed for resisting fatty liver of grass carp |
| CN102210411A (en) * | 2011-06-08 | 2011-10-12 | 广东恒兴饲料实业股份有限公司 | Compound feed capable of improving fatty liver and body colour of marine fish and preparation method thereof |
| CN102210411B (en) * | 2011-06-08 | 2013-02-06 | 广东恒兴饲料实业股份有限公司 | Compound feed capable of improving fatty liver and body color of marine fish and preparation method thereof |
| CN102283332A (en) * | 2011-08-25 | 2011-12-21 | 北京大北农科技集团股份有限公司 | Feed additive and premix compound for promoting grass carp liver and immunologic function repair |
| CN102283332B (en) * | 2011-08-25 | 2013-04-10 | 北京大北农科技集团股份有限公司 | Feed additive and premix compound for promoting grass carp liver and immunologic function repair |
| CN103989023A (en) * | 2014-06-09 | 2014-08-20 | 中山大学 | Special anti-fatty liver additive for hybrid snakehead and preparation method thereof |
| CN103989023B (en) * | 2014-06-09 | 2016-02-24 | 中山大学 | Special AFL additive of a kind of hybridized snakehead fish and preparation method thereof |
| CN107242162A (en) * | 2017-06-07 | 2017-10-13 | 珠海市斗门区河口渔业研究所 | A kind of cultural method for preventing and treating jewfish fatty liver |
| CN107455613A (en) * | 2017-09-11 | 2017-12-12 | 浙江海洋大学 | A kind of feed that can improve large yellow croaker fatty liver and preparation method thereof |
| CN107455613B (en) * | 2017-09-11 | 2020-09-08 | 浙江海洋大学 | Feed capable of improving fatty liver of large yellow croaker and preparation method thereof |
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| CN101283739B (en) | 2011-01-19 |
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Owner name: GUANGDONG EVERGREEN FEED INDUSTRY CO., LTD. Free format text: FORMER OWNER: GUANGDONG HENGXING GROUP CO., LTD. Effective date: 20110614 |
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Effective date of registration: 20110614 Address after: Jin Kang Road 524094 Guangdong city of Zhanjiang province Mazhang Economic Development Zone Patentee after: Guangdong Evergreen Feed Industrial Co., Ltd. Address before: Jin Kang Road, Mazhang District 510627 Guangdong city of Zhanjiang Province Patentee before: Guangdong Hengxing Group Co., Ltd. |