CN101278987A - Chinese medicine compound for nourishing yin and tonifying kidney, benefiting-qi and promoting blood circulation, enriching blood and benefiting semen - Google Patents
Chinese medicine compound for nourishing yin and tonifying kidney, benefiting-qi and promoting blood circulation, enriching blood and benefiting semen Download PDFInfo
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Abstract
The invention discloses a Chinese medicine composition used for nourishing kidney-Yin, supplementing Qi, activating blood circulation, strengthening blood and replenishing vital essence. The effective components of the invention are extracted from over ten medicine materials such as astragalus, radix saposhnikoviae, atractylodes, caulis spatholobi, colla corii asini, colla cornus cervi, herba agrimoniae, fructus psoralea, lithospermum, placenta hominis, rhubarb, ginseng, codonopsis pilosula, polygonum cuspidate, glossy privet fruit and radix polygoni multiflori preparata, etc. The special active medicinal components provided by the invention have the effects of nourishing kidney-Yin, supplementing Qi, activating blood circulation, strengthening blood and replenishing vital essence and are applicable to treating aplastic anemia.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to the Chinese medicine composition of a kind of enriching yin and nourishing kidney, benefiting QI for activating blood circulation, the replenishing essence of enriching blood.
Technical background
Aplastic anemia is that one group of hematopoietic stem cell that is caused by chemistry, physics, biological factor and unknown cause is impaired, the hematopoieticmicroenviron-ment damage, and immune function is unusual, thereby causes hemopoietic tissue to reduce hematopoietic function depletion, pancytopenia.Its main clinical manifestation is the simultaneous phenomenon of anemia and anemia, leukopenia and the infection disease that causes therefrom, and thrombocytopenia and the bleeding tendency that causes therefrom.The normal onset of chronic aplastic anemia is slow, and the course of disease is longer, how with the anemia onset, and is main performance with the anemia, and is hemorrhage and infect slighter.According to its clinical manifestation, the traditional Chinese medical science thinks that this disease belongs to " asthenia ", " blood deficiency " category.
The traditional Chinese medical science is thought Lao Bixu, and fictitious pole must become labor, and cause void because of very complicated.One is physical factors, and body constitution is determining the tendentiousness of human body to the susceptibility of disease and pathogenesis, syndrome, and the natural endowment decisive role.Father and mother's body void, mistake is supported, is bred deficiency and all can cause the natural endowment weakness in the tire, deficiency of the kidney, bone marrow inanition, body constitution are not strong.The 2nd, life factor comprises imbalances such as diet, daily life, feelings will, overstrain, all can cause body and the spirit to cross consumption, undermines the five internal organs.The wound of the five internal organs must reach kidney thoroughly, deficiency of the kidney, and precise and tiny can not the envelope hidden astringency inducing at kidney, and kidney essense is not filled, and can not change and give birth to cloudy blood, with the passing of time gradually becomes asthenia.The 3rd, other diseases causes, the sudden and violent disease of serious disease, and pathogen is contained very much, the visceral-qi damage, deficiency of vital QI is with the passing of time difficult multiple after being ill, lose in medical treatment in addition, or the smart consumption of prolonged illness wound gas, the source exhaustion of QI and blood, or knot in the blood stasis, fresh blood is living, all can cause the vital essence consumption to be hindered, and with the passing of time gradually becomes asthenia.The above-mentioned three class causes of disease all can cause deficiency of the kidney, can not grow blood, and the withered marrow sky of hyperamization causes aplastic anemia.As seen suffering from a deficiency of the kidney is the key that chronic aplastic anemia takes place.The kidney being the origin of congenital constitution, in post nephroyin and nephroyang, the Yintu(K19) of human five internal organs's six internal organs is grown by kidney yin, the sun of the vital organs of the human body all comes replenishing vital QI with drugs of warm nature by kidney yang.If insufficiency of primordial QI in the kidney, unable promotion and excite the physiological function of each internal organs, dysfunction of the spleen in transportation then, lung loses a surname and sends out and spreading, and the liver failing to maintain the normal flow of QI, the motive can not promote that blood is capable then can't change hemopoietic liquid.The strong and weak physiological function of body and the deficiency and excess of bone marrow of directly influencing of renal function.Essence and blood sharing the same origin, then blood is prosperous for smart foot, and damage of essence is insufficiency of blood then.If renal function is healthy and vigorous, though blood deficiency is arranged, kidney essense still can transform, and blood can be regenerated.If deficiency of the kidney, essence and blood is difficult to transform and essence and blood then can occurs and all lose, thereby causes aplastic anemia.
Summary of the invention:
One of purpose of the present invention provides a kind of enriching yin and nourishing kidney, benefiting QI for activating blood circulation, the Chinese medicine composition of the replenishing essence of enriching blood.
Another object of the present invention provides the preparation method of this Chinese medicine composition.
Chinese medicine of the present invention is made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made (part is unit of weight) by following raw materials according:
1, prescription:
Radix Astragali 80-240 part Radix Saposhnikoviae 60-180 part Rhizoma Atractylodis Macrocephalae 60-180 part
Caulis Spatholobi 60-180 part Colla Corii Asini 60-180 part Colla cornus cervi 60-180 part
Herba Agrimoniae 60-180 part Fructus Psoraleae 60-180 part Radix Arnebiae (Radix Lithospermi) 60-180 part
Placenta Hominis 60-180 part Radix Et Rhizoma Rhei 80-240 part Radix Ginseng 80-240 part
Radix Codonopsis 80-240 part Rhizoma Polygoni Cuspidati 60-180 part Fructus Ligustri Lucidi 60-180 part
Radix Polygoni Multiflori Preparata 60-180 part
The active component that preferred following raw materials according is made, curative effect is better:
120 parts of 120 parts of Rhizoma Atractylodis Macrocephalaes of 160 parts of Radix Saposhnikoviaes of the Radix Astragali
120 parts of 120 parts of Colla cornus cervis of 120 parts of Colla Corii Asini of Caulis Spatholobi
120 parts of 120 portions of Radix Arnebiae (Radix Lithospermi)s of 120 parts of Fructus Psoraleaes of Herba Agrimoniae
160 parts of 160 parts of Radix Ginsengs of 120 parts of Radix Et Rhizoma Rhei of Placenta Hominis
120 parts of 120 parts of Fructus Ligustri Lucidi of 160 parts of Rhizoma Polygoni Cuspidati of Radix Codonopsis
120 parts of Radix Polygoni Multiflori Preparata
The active ingredient preparation method of Chinese medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.
The following preparation method preparation of preferred employing:
2, preparation technology
(1) Radix Astragali, Radix Et Rhizoma Rhei add 80% alcohol dipping three times, flood 48 hours for the first time, and second and third time flooded respectively 24 hours, filter, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Radix Saposhnikoviaes, the Rhizoma Atractylodis Macrocephalae, Caulis Spatholobi, Herba Agrimoniae, Fructus Psoraleae, Radix Arnebiae (Radix Lithospermi), Placenta Hominis, Radix Ginseng, Radix Codonopsis, Rhizoma Polygoni Cuspidati, Fructus Ligustri Lucidi, Radix Polygoni Multiflori Preparata add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is boiled the back and is added Colla Corii Asini, Colla cornus cervi, stirs to make and dissolves, and concentrating under reduced pressure becomes the clear paste of 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, be ground into fine powder, add acceptable accessories and make different preparations such as granule, sheet, capsule.
Adopt mutual compatibility of above-mentioned raw material of Chinese medicine and preparation method thereof, full side has enriching yin and nourishing kidney, benefiting QI for activating blood circulation, the effect of the replenishing essence of enriching blood, and is used for the treatment of aplastic anemia.
By the following examples technical scheme of the present invention is described further.
Embodiment 1: the preparation method of granule
1, prescription:
120 parts of 120 parts of Rhizoma Atractylodis Macrocephalaes of 160 parts of Radix Saposhnikoviaes of the Radix Astragali
120 parts of 120 parts of Colla cornus cervis of 120 parts of Colla Corii Asini of Caulis Spatholobi
120 parts of 120 portions of Radix Arnebiae (Radix Lithospermi)s of 120 parts of Fructus Psoraleaes of Herba Agrimoniae
160 parts of 160 parts of Radix Ginsengs of 120 parts of Radix Et Rhizoma Rhei of Placenta Hominis
120 parts of 120 parts of Fructus Ligustri Lucidi of 160 parts of Rhizoma Polygoni Cuspidati of Radix Codonopsis
120 parts of Radix Polygoni Multiflori Preparata
2, preparation technology:
(1) Radix Astragali, Radix Et Rhizoma Rhei add 80% alcohol dipping three times, flood 48 hours for the first time, and second and third time flooded respectively 24 hours, filter, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Radix Saposhnikoviaes, the Rhizoma Atractylodis Macrocephalae, Caulis Spatholobi, Herba Agrimoniae, Fructus Psoraleae, Radix Arnebiae (Radix Lithospermi), Placenta Hominis, Radix Ginseng, Radix Codonopsis, Rhizoma Polygoni Cuspidati, Fructus Ligustri Lucidi, Radix Polygoni Multiflori Preparata add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is boiled the back and is added Colla Corii Asini, Colla cornus cervi, stirs to make and dissolves, and concentrating under reduced pressure becomes the clear paste of 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, add cane sugar powder, mixing is made granule, drying, promptly.
Embodiment 2: the preparation method of tablet
1, prescription:
120 parts of 120 parts of Rhizoma Atractylodis Macrocephalaes of 160 parts of Radix Saposhnikoviaes of the Radix Astragali
120 parts of 120 parts of Colla cornus cervis of 120 parts of Colla Corii Asini of Caulis Spatholobi
120 parts of 120 portions of Radix Arnebiae (Radix Lithospermi)s of 120 parts of Fructus Psoraleaes of Herba Agrimoniae
160 parts of 160 parts of Radix Ginsengs of 120 parts of Radix Et Rhizoma Rhei of Placenta Hominis
120 parts of 120 parts of Fructus Ligustri Lucidi of 160 parts of Rhizoma Polygoni Cuspidati of Radix Codonopsis
120 parts of Radix Polygoni Multiflori Preparata
2. preparation technology:
(1) Radix Astragali, Radix Et Rhizoma Rhei add 80% alcohol dipping three times, flood 48 hours for the first time, and second and third time flooded respectively 24 hours, filter, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Radix Saposhnikoviaes, the Rhizoma Atractylodis Macrocephalae, Caulis Spatholobi, Herba Agrimoniae, Fructus Psoraleae, Radix Arnebiae (Radix Lithospermi), Placenta Hominis, Radix Ginseng, Radix Codonopsis, Rhizoma Polygoni Cuspidati, Fructus Ligustri Lucidi, Radix Polygoni Multiflori Preparata add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is boiled the back and is added Colla Corii Asini, Colla cornus cervi, stirs to make and dissolves, and concentrating under reduced pressure becomes the clear paste of 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, pulverize, sieve, add starch, magnesium stearate, tabletting, promptly.
Embodiment 3: the preparation method of capsule
1, prescription:
120 parts of 120 parts of Rhizoma Atractylodis Macrocephalaes of 160 parts of Radix Saposhnikoviaes of the Radix Astragali
120 parts of 120 parts of Colla cornus cervis of 120 parts of Colla Corii Asini of Caulis Spatholobi
120 parts of 120 portions of Radix Arnebiae (Radix Lithospermi)s of 120 parts of Fructus Psoraleaes of Herba Agrimoniae
160 parts of 160 parts of Radix Ginsengs of 120 parts of Radix Et Rhizoma Rhei of Placenta Hominis
120 parts of 120 parts of Fructus Ligustri Lucidi of 160 parts of Rhizoma Polygoni Cuspidati of Radix Codonopsis
120 parts of Radix Polygoni Multiflori Preparata
2. preparation technology:
(1) Radix Astragali, Radix Et Rhizoma Rhei add 80% alcohol dipping three times, flood 48 hours for the first time, and second and third time flooded respectively 24 hours, filter, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Radix Saposhnikoviaes, the Rhizoma Atractylodis Macrocephalae, Caulis Spatholobi, Herba Agrimoniae, Fructus Psoraleae, Radix Arnebiae (Radix Lithospermi), Placenta Hominis, Radix Ginseng, Radix Codonopsis, Rhizoma Polygoni Cuspidati, Fructus Ligustri Lucidi, Radix Polygoni Multiflori Preparata add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is boiled the back and is added Colla Corii Asini, Colla cornus cervi, stirs to make and dissolves, and concentrating under reduced pressure becomes the clear paste of 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, pulverize, sieve, add starch, mixing is made granule, and drying incapsulates, promptly.
Claims (5)
- The Chinese medicine composition of 1, a kind of enriching yin and nourishing kidney, benefiting QI for activating blood circulation, the replenishing essence of enriching blood is characterized in that being made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made by following raw materials according:Radix Astragali 80-240 part Radix Saposhnikoviae 60-180 part Rhizoma Atractylodis Macrocephalae 60-180 partCaulis Spatholobi 60-180 part Colla Corii Asini 60-180 part Colla cornus cervi 60-180 partHerba Agrimoniae 60-180 part Fructus Psoraleae 60-180 part Radix Arnebiae (Radix Lithospermi) 60-180 partPlacenta Hominis 60-180 part Radix Et Rhizoma Rhei 80-240 part Radix Ginseng 80-240 partRadix Codonopsis 80-240 part Rhizoma Polygoni Cuspidati 60-180 part Fructus Ligustri Lucidi 60-180 partRadix Polygoni Multiflori Preparata 60-180 part.
- 2, the Chinese medicine composition of a kind of enriching yin and nourishing kidney according to claim 1, benefiting QI for activating blood circulation, the replenishing essence of enriching blood is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:120 parts of 120 parts of Rhizoma Atractylodis Macrocephalaes of 160 parts of Radix Saposhnikoviaes of the Radix Astragali120 parts of 120 parts of Colla cornus cervis of 120 parts of Colla Corii Asini of Caulis Spatholobi120 parts of 120 portions of Radix Arnebiae (Radix Lithospermi)s of 120 parts of Fructus Psoraleaes of Herba Agrimoniae160 parts of 160 parts of Radix Ginsengs of 120 parts of Radix Et Rhizoma Rhei of Placenta Hominis120 parts of 120 parts of Fructus Ligustri Lucidi of 160 parts of Rhizoma Polygoni Cuspidati of Radix Codonopsis120 parts of Radix Polygoni Multiflori Preparata.
- 3, according to the Chinese medicine composition of the described a kind of enriching yin and nourishing kidney of claim 1-2, benefiting QI for activating blood circulation, the replenishing essence of enriching blood, it is characterized in that adopting following method to make:(1) Radix Astragali, Radix Et Rhizoma Rhei add 80% alcohol dipping three times, flood 48 hours for the first time, and second and third time flooded respectively 24 hours, filter, and decompression filtrate recycling ethanol is condensed into the thick paste shape, the thousands of cream of vacuum drying below 85 ℃;(2) medical materials such as all the other Radix Saposhnikoviaes, the Rhizoma Atractylodis Macrocephalae, Caulis Spatholobi, Herba Agrimoniae, Fructus Psoraleae, Radix Arnebiae (Radix Lithospermi), Placenta Hominis, Radix Ginseng, Radix Codonopsis, Rhizoma Polygoni Cuspidati, Fructus Ligustri Lucidi, Radix Polygoni Multiflori Preparata add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is boiled the back and is added Colla Corii Asini, Colla cornus cervi, stirs to make and dissolves, and concentrating under reduced pressure becomes the clear paste of 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;(3) step (1) get dry extract is got dry extract with step (2) mix, be ground into fine powder, add acceptable accessories and make different preparations such as granule, sheet, capsule.
- 4,, it is characterized in that this Chinese medicine composition is an oral formulations according to the Chinese medicine composition of any one described a kind of enriching yin and nourishing kidney, benefiting QI for activating blood circulation, the replenishing essence of enriching blood among the claim 1-3.
- 5,, it is characterized in that this Chinese medicine composition can be made into granule, capsule, tablet according to the Chinese medicine composition of the described a kind of enriching yin and nourishing kidney of claim 3-4, benefiting QI for activating blood circulation, the replenishing essence of enriching blood.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103083541A (en) * | 2013-02-02 | 2013-05-08 | 徐美玲 | Drug for treating anemia |
| CN103083614A (en) * | 2011-10-28 | 2013-05-08 | 张志通 | Medicine formula for treating chronic aplastic anemia |
| CN103598498A (en) * | 2013-10-15 | 2014-02-26 | 鲁杨 | Sea sedge-chicken egg roll |
| CN104256294A (en) * | 2014-09-10 | 2015-01-07 | 柏伟伟 | Health care congee used for treating postpartum anemic fainting of women and preparation method thereof |
| CN104398667A (en) * | 2014-12-05 | 2015-03-11 | 于泽顺 | Traditional Chinese medicinal preparation for treating leucopenia after radiotherapy |
| CN106668790A (en) * | 2015-11-04 | 2017-05-17 | 哈尔滨圣吉药业股份有限公司 | Human placenta soluble granules having effects of reinforcing qi and nourishing blood and preparation method thereof |
| CN113332361A (en) * | 2021-07-05 | 2021-09-03 | 吉林白山正茂药业股份有限公司 | Traditional Chinese medicine composition for preventing and treating aplastic anemia and preparation method thereof |
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2008
- 2008-05-04 CN CNA2008101058466A patent/CN101278987A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103083614A (en) * | 2011-10-28 | 2013-05-08 | 张志通 | Medicine formula for treating chronic aplastic anemia |
| CN103083541A (en) * | 2013-02-02 | 2013-05-08 | 徐美玲 | Drug for treating anemia |
| CN103083541B (en) * | 2013-02-02 | 2015-01-28 | 李敏 | Drug for treating anemia |
| CN103598498A (en) * | 2013-10-15 | 2014-02-26 | 鲁杨 | Sea sedge-chicken egg roll |
| CN104256294A (en) * | 2014-09-10 | 2015-01-07 | 柏伟伟 | Health care congee used for treating postpartum anemic fainting of women and preparation method thereof |
| CN104398667A (en) * | 2014-12-05 | 2015-03-11 | 于泽顺 | Traditional Chinese medicinal preparation for treating leucopenia after radiotherapy |
| CN106668790A (en) * | 2015-11-04 | 2017-05-17 | 哈尔滨圣吉药业股份有限公司 | Human placenta soluble granules having effects of reinforcing qi and nourishing blood and preparation method thereof |
| CN113332361A (en) * | 2021-07-05 | 2021-09-03 | 吉林白山正茂药业股份有限公司 | Traditional Chinese medicine composition for preventing and treating aplastic anemia and preparation method thereof |
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