CN101249060A - Multiple-effect washing cream and method of preparing the same - Google Patents
Multiple-effect washing cream and method of preparing the same Download PDFInfo
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- CN101249060A CN101249060A CNA2008100605615A CN200810060561A CN101249060A CN 101249060 A CN101249060 A CN 101249060A CN A2008100605615 A CNA2008100605615 A CN A2008100605615A CN 200810060561 A CN200810060561 A CN 200810060561A CN 101249060 A CN101249060 A CN 101249060A
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Abstract
The invention relates to multifunctional face cream and a preparation method thereof. The face cream is made from and combines Sargassum fusiforme extract obtained by an ultrasonic extraction method and other components beneficial for skin care. The Sargassum fusiforme extract contains polysaccharides of Sargassum fusiforme, vitamin E, vitamin C, SOD and other skin-caring components, and has moisturizing, antioxidant and antiaging effects. The face cream has multiple functions, and the extraction of the Sargassum fusiforme extract is simple. The raw materials of the face cream are easy to obtain and the preparation method thereof is simple.
Description
Technical field
The present invention relates to cosmetic field, specifically refer to a kind of multiple-effect washing cream and preparation method thereof with non-oxidizability and performance of keeping humidity.
Background technology
Along with growth in the living standard, people are also more and more higher to the requirement of cosmetics, wish to use to contain natural health composition and the significant skin care item of effect.Sargassum fusiforme (Harv.) Setch is a kind of seaweed plant, and the polysaccharide that is contained in its extract has plurality of health care functions, and for example effects such as the blood fat reducing that it had, blood glucose, antitumor, antiviral, defying age, antiinflammatory have become the raw material that cosmetic field is favored.Not only contain the composition of polysaccharide in the Sargassum fusiforme (Harv.) Setch, also contain other useful compositions such as VE, SOD.According to the difference of extraction process, the effective ingredient in the Sargassum fusiforme (Harv.) Setch extract is also different, so the effect that it had is also different.The Sargassum fusiforme (Harv.) Setch extract has been applied in the multiple field at present, but its report that is applied in cosmetic field is few.
Summary of the invention
Technical problem to be solved by this invention is the situation at prior art, and a kind of Sargassum fusiforme (Harv.) Setch extract multiple-effect washing cream preparation, that have efficient moisture-retention, resisting oxidation free radical, anti aging effect that utilizes is provided.
Another technical problem to be solved by this invention is the situation at prior art, provide a kind of utilize Sargassum fusiforme (Harv.) Setch extract preparation, have a preparation method of the multiple-effect washing cream of efficient moisture-retention, resisting oxidation free radical, anti aging effect.
The present invention solves the problems of the technologies described above the technical scheme that is adopted: this multiple-effect washing cream is characterized in that comprising following component: (if no special instructions, the content of all components is mass percent)
Squalane 5-10%
Hexadecanol 2-5%
Liquid paraffin 10-15%
Tween-60 2-3%
Tristerin 2-3%
Glycerol 5-10%
Sargassum fusiforme (Harv.) Setch extract B 10-20%
Sargassum fusiforme (Harv.) Setch extract C 1.5-2.5%
Sargassum fusiforme (Harv.) Setch extract D 0.5-1.5%
Ascorbic acid 2-3%
Methyl parahydroxybenzoate 0.2-0.3%
Polyethylene Glycol 5-7%
Essential oil 0.01-0.05
The aquesterilisa surplus
Wherein, described Sargassum fusiforme (Harv.) Setch preparation method of extract is as follows:
At first prepare the Sargassum fusiforme (Harv.) Setch extract A: after using the clear water rinsing clean Sargassum fusiforme (Harv.) Setch,, cross 80 mesh sieves after pulverizer is pulverized and obtain dry powder 50-60 ℃ of oven dry; Dry powder was added flooding 2～3 hours, and wherein the mass ratio of dry powder and water is 1: 30-40; With ultrasound wave centrifugal sedimentation after handling 10-12 minute under the 800-1200W condition, obtain supernatant one and precipitate one; Precipitate one water under 70-80 ℃ of temperature is carried 1-2 hour, and centrifugal sedimentation gets supernatant two and precipitate two again; Precipitate dual-purpose 2% carbonic acid soda is carried 1-2 hour, with the centrifugal supernatant three that gets of method; Mixing supernatant one, two, three is also regulated its pH value to 7.0, concentrates in 0.1Mpa, 50-60 ℃ reduced vacuum and obtains concentrated solution; Concentrated solution is used the ethanol precipitation of volume fraction 65-70% then with Sevage method Deproteinization 2-4 time, and precipitate is used 1 successively: the acetone of 5-10, absolute ethanol washing, filtration obtain Sargassum fusiforme (Harv.) Setch extract A crude product with the precipitate vacuum decompression drying that obtains; Sargassum fusiforme (Harv.) Setch extract A crude product is used 1 successively: after the Rhizoma Zingiberis Recens of 6-10 went the granular active carbon absorption of raw meat, 1: 10-15, centrifugation obtained supernatant again, behind supernatant liquid filtering, use 2-5: the decolouring of 1AB-8 macroporous adsorbent resin, filter, get its filtrate, be the Sargassum fusiforme (Harv.) Setch extract A;
The preparation of Sargassum fusiforme (Harv.) Setch extract B: fresh Sargassum fusiforme (Harv.) Setch is clean with the clear water rinsing, 55 ℃ of oven dry then, pulverize 80 mesh sieves and obtained dry powder, with dry powder: water is 1: the ratio of 30-40 adds distilled water, 800-1200W supersound process 10-12 minute, lixiviate 2-4 hour in the time of 4 ℃ then, centrifugal precipitate and the supernatant of getting, drying precipitate, supernatant 6-15: after 1 Rhizoma Zingiberis Recens removes raw meat, reuse 10-15: 1 granular active carbon absorption, centrifugal sedimentation again is behind supernatant liquid filtering, liquid 4-10: 1 AB-8 macroporous adsorbent resin decolouring, filter and obtain filtrate Sargassum fusiforme (Harv.) Setch extract B;
The preparation of Sargassum fusiforme (Harv.) Setch extract C: the aqueous solution of the Sargassum fusiforme (Harv.) Setch extract A being made 1-2%, through the DEAE-52 ion-exchange resin purification, with 2% sodium chloride eluting, merge and collect the polysaccharide liquid that detects through the sulphuric acid phynol method, 3500 molecular weight dialyzer desalinations, polysaccharide solids with obtaining obtains the Sargassum fusiforme (Harv.) Setch extract C through vacuum lyophilization;
The preparation of Sargassum fusiforme (Harv.) Setch extract D: after the rinsing totally of Sargassum fusiforme (Harv.) Setch usefulness clear water,, pulverized 80 mesh sieves then and obtain dry powder 50-60 ℃ of oven dry; With 3-4: 1 ratio adds ethanol chloroform water mixed solution dissolving (ethanol: chloroform: the ratio of water is 2: 1: 0.8) in dry powder after, in 50-60 ℃ of water-bath, extract fatty acid, after extraction time is 2-3 hour, at room temperature left standstill 8-12 hour, centrifugal sedimentation is then got supernatant and is added 5: 2 chloroform extractions 2-3 time, and the collection chloroform layer is removed moisture content with anhydrous sodium sulfate drying, at 0.1Mpa, 50-60 ℃ of evaporative removal chloroform solvent, last inflated with nitrogen is dry must Sargassum fusiforme (Harv.) Setch extract D then.
Preferably, centrifugal sedimentation speed is 4000-5000 rev/min in the preparation of described Sargassum fusiforme (Harv.) Setch extract, and centrifugation time is 10-12 minute.
Adopt supercritical ultrasonics technology to prepare the Sargassum fusiforme (Harv.) Setch extract among the present invention, except the polysaccharide in the Sargassum fusiforme (Harv.) Setch is extracted, supercritical ultrasonics technology can also keep VE, VC in the Sargassum fusiforme (Harv.) Setch, SOD etc. and have the composition to skin beneficiating such as defying age, antioxidation, can give therefore that this facial cream is preserved moisture, antioxidation, the anti-ageing effect of waiting for a long time.
Prepare the method for above-mentioned multiple-effect washing cream, comprise the steps:
A) squalane of 5-10%, the paraffin oil of 10-15% and the Sargassum fusiforme (Harv.) Setch extract D mixing of 0.5-1.5% are obtained oil phase A, oil phase A is put into 70-80 ℃ of water-bath heating dissolve each other, 70-80 ℃ of insulation;
B) 1.5-2.5% Sargassum fusiforme (Harv.) Setch extract C, 5-10% glycerol and the mixing of 10-20% aquesterilisa are obtained aqueous phase B;
C) tristerin of 2-3% and the Tween-60 of 2-3% are mixed into compound emulsifying agent in 70-80 ℃ of water-bath;
D) aqueous phase B that step b is obtained in 70-80 ℃ of water-bath, heat dissolve each other after, the compound emulsifying agent that step c is obtained adds and wherein stirs, the oil phase A that step a is obtained slowly adds wherein then, and is stirred to complete emulsifying;
E) add the Polyethylene Glycol of 5-7%, the hexadecanol of 2-5%, the essential oil of 0.01-0.05%, the methyl parahydroxybenzoate of 0.2-0.3% again, slowly be cooled to below 40-50 ℃, and then add the aquesterilisa of the ascorbic acid of Sargassum fusiforme (Harv.) Setch extract B, 2-3% of 10-20% and 10-55% and stir, and put into colloid mill and fully be packaged to be finished product behind the vacuum emulsification.
Compared with prior art, multiple-effect washing cream provided by the present invention is because contain the Sargassum fusiforme (Harv.) Setch extract that adopts ultrasonic technique to extract, so include in the facial cream Hijiki polysaccharide, VE, VC, SOD etc. multiple have preserve moisture, the skin protection composition of antioxidation, anti-aging effect, give this facial cream multiple function, and the extraction process of Sargassum fusiforme (Harv.) Setch extract is simple.The raw material that facial cream the adopted preparation method that is easy to get is simple.
Description of drawings
Fig. 1 be in the embodiment of the invention 1 several facial creams in the percentage of water loss test result of RH40 ± 5% o'clock.
The specific embodiment
Below in conjunction with embodiment the present invention is described in further detail.
At first prepare the Sargassum fusiforme (Harv.) Setch extract A: after using the clear water rinsing clean Sargassum fusiforme (Harv.) Setch, 55 ℃ of oven dry, pulverized 80 mesh sieves with the high speed Universalpulverizer then and obtain dry powder, dry powder was added flooding 2 hours, wherein the mass ratio of dry powder and water is 1: 30; With supersonic cell crusher 800W ultrasonic Treatment 12 minutes, 4500 rev/mins of said extracted things is centrifugal 11 minutes, precipitate water under 75 ℃ of temperature is carried 1 hour, the same method is centrifugal, precipitation reuse 2% carbonic acid soda is carried 2 hours, centrifugal with method, merge the above-mentioned gained supernatant that respectively goes on foot, regulate supernatant pH value to 7.0,0.1Mpa 60 ℃ of Rotary Evaporators reduced vacuum concentrate, concentrated solution Sevage method Deproteinization 2 times, the supernatant ethanol precipitation of volume fraction 70%, precipitate successively used 1: 5 acetone, absolute ethanol washing, precipitate drying in the vacuum decompression drying baker obtains Sargassum fusiforme (Harv.) Setch extract A crude product.After Sargassum fusiforme (Harv.) Setch extract A crude product gone raw meat, granular active carbon absorption in 1: 10 with 1: 6 Rhizoma Zingiberis Recens, through 5000 rev/mins centrifugal 10 minutes, behind the supernatant liquid filtering,, filter and obtain the Sargassum fusiforme (Harv.) Setch extract A with 5: 1 AB-8 macroporous adsorbent resins decolouring; (concrete method of testing is with reference to " Harbin University of Commerce's journal ", and 2006 the 1st phases, Hijiki polysaccharide extracts and assay through the sulphuric acid phynol method; " Biochemistry Experiment method and technology ", Science Press, reducing sugar and total sugar content are fixed) test, the main component of Sargassum fusiforme (Harv.) Setch extract A is an active polysaccharide;
Prepare the Sargassum fusiforme (Harv.) Setch extract B: after fresh Sargassum fusiforme (Harv.) Setch is used the clear water rinsing, 50 ℃ of oven dry, 55 ℃ of oven dry then, obtained dry powder after pulverizing 80 mesh sieves, ratio with 1: 35 in the phase dry powder adds distilled water, place ice bath to use supersonic cell crusher 1000W supersound process 10 minutes, 4 ℃ of lixiviates 2 hours, under 4500 rev/mins the speed centrifugal 11 minutes, behind the supernatant liquid filtering that obtains, remove raw meat with 10: 1 Rhizoma Zingiberis Recenss, reuse granular active carbon absorption in 10: 1, under 4000 rev/mins the speed centrifugal 12 minutes, behind the supernatant liquid filtering, with 4: after the decolouring of 1AB-8 macroporous adsorbent resin, filtration obtains the Sargassum fusiforme (Harv.) Setch extract B, and aforesaid operations carries out under 4 ℃ of conditions; Through super oxidation qi enzyme activity detection, 2, the 6-Dichlorophenol indophenol is surveyed vitamin C method (method of testing is with reference to " Biochemistry Experiment principle and method ", BJ University Press) test, and the main component of Sargassum fusiforme (Harv.) Setch extract B is SOD, vitamin C;
Preparation Sargassum fusiforme (Harv.) Setch extract C: the Sargassum fusiforme (Harv.) Setch extract A is made with extra care, it is dissolved into 1% aqueous solution, DEAE-52 cellulose anion-exchange column, 2% sodium chloride eluting through liquid chromatography (LC) instrument Φ 2 * 40cm, merge and collect through the detected polysaccharide liquid of sulphuric acid phynol method, and then through 3500 molecular weight membrane distillation water dialysis desaltings, vacuum lyophilization gets the Sargassum fusiforme (Harv.) Setch extract C under 60 ℃, 0.1MPa then;
The preparation of Sargassum fusiforme (Harv.) Setch extract D: after the rinsing totally of Sargassum fusiforme (Harv.) Setch usefulness clear water, 60 ℃ of oven dry, pulverize 80 mesh sieves then and obtained dry powder, in dry powder, add the dissolving of ethanol chloroform water mixed solution with 3.5: 1 ratios, ethanol wherein: chloroform: the ratio of water is 2: 1: 0.8, after lixiviate was extracted fatty acid in 2 hours in 60 ℃ of water-baths, left standstill 10 hours, extract was descended centrifugal 12 minutes at 4000 rev/mins, go precipitation, add 5: 2 chloroform extractions 3 times in supernatant, the chloroform layer of collection is removed moisture content with anhydrous sodium sulfate drying, send to rotary evaporation then and remove chloroform solvent, last inflated with nitrogen drying obtains Sargassum fusiforme (Harv.) Setch extract D.
Test through the makings chromatograph, the main component of Sargassum fusiforme (Harv.) Setch extract D is a fatty acid, its method of testing is as follows: get 1.0 gram Sargassum fusiforme (Harv.) Setch extract D, with the lixiviate of benzene petroleum ether solution, the esterification of reuse NaOH-CH3OH solution, use n-hexane extraction, use analytically clear liquid of makings chromatograph (TRACE-DSQ II MS).
Gas phase condition: PTV injection port, 270 ℃ of temperature.140 ℃ of the initial column temperatures of chromatographic column kept 1 minute, and the speed with 4.0 ℃/min is warmed up to 215 ℃ then, kept 5 minutes, and the speed with 2.8 ℃/min is warmed up to 240 ℃ again, kept 5 minutes.With high-purity He is carrier gas, flow velocity 1.0mL/min, and split ratio 50: 1, sample size is 1mL.
Mass spectrum condition: mass ion source EI, 250 ℃ of temperature, energy 70V, heater current 100mA, 250 ℃ of line of transference temperature, omnidistance scanning, mass range 40-300amu, the initial acquisition time 4.20min of data.
According to the fragment ion quality spectrogram of each component among the gaschromatographic mass spectrometry total ion current figure, utilize computer spectrum storehouse to point out, and the main component of checking to determine the Sargassum fusiforme (Harv.) Setch extract by standard substance is a fatty acid.
The preparation multiple-effect washing cream:
Squalane with 5%, 12% paraffin oil and 0.5% Sargassum fusiforme (Harv.) Setch extract D mix and obtain oil phase A, oil phase A is put into 80 ℃ of water-baths heating dissolve each other, 80 ℃ of insulations; Sargassum fusiforme (Harv.) Setch extract C with 2%, 5% glycerol and 17.25% aquesterilisa mix and obtain aqueous phase B; Tristerin with 2% and 2% Tween-60 are put into 75 ℃ of water-baths and are endured and become compound emulsifying agent;
Above-mentioned aqueous phase B after 80 ℃ of heating in water bath dissolve each other, is wherein stirred the compound emulsifying agent adding, and the oil phase A that will dissolve each other then slowly adds in the aqueous phase B, and the limit edged stirs, to emulsifying fully; Add 5% Polyethylene Glycol, 2% hexadecanol, 0.05% essential oil, 0.2% methyl parahydroxybenzoate again, stir and slowly be cooled to 45 ℃, after the aquesterilisa that adds 15% Sargassum fusiforme (Harv.) Setch extract B, 2% ascorbic acid and 30% then stirs, put into the abundant once more vacuum emulsification of colloid mill, packing.
The validation test of facial cream effect:
The test method of performance of keeping humidity and result
External weight method: take by weighing following each 5.0g of EXPERIMENTAL DESIGN table 1 prescription sample respectively, evenly be applied to and be stained with 3cm adhesive plaster, size in the weighing botle of Φ 40 * 25, do not add a cover, place 29 ℃, relative humidity (RH) is in 40% ± 5% the constant temperature and humidity plant incubator, took out weighing every 3 hours, weighing results is as shown in table 1; Parallel test 3 times is calculated as follows average percentage of water loss, its time-percentage of water loss concerns as shown in Figure 1:
Percentage of water loss %=W1-W2/W1-W * 100%;
Wherein, the weighing botle weight of sample before the W1-experiment, gram;
Sample and weighing botle weight behind the W2-specific time interval, gram;
W-weighing botle weight, gram.
The performance of keeping humidity test of the facial cream of table 1: embodiment preparation and like product relatively
The test of DPPH non-oxidizability:
The method that DPPH non-oxidizability detection method was provided with reference to Larrauri and Yokozawa " biochemistry and biophysics progress " 2006 the 6th phases of periodical " with removing organic free radical DPPH method evaluation plant oxidation resistance ", utilize the absworption peak of the feature aubergine group of DPPH solution, with spectrophotometry, add OD514 absorbs behind antioxidant or the plant extraction liquid decline and represent that it eliminates ability to organic free radical.DPPH dissolves with small amount of ethanol earlier, and is mixed with 1 * 10-4mol/L with 10% ethanol, keeps in Dark Place.Get 2mLDPPH solution, add 2mL facial cream extracting solution and fully mix.Measure its OD514 at 514nm (maximum absorption wave strong point) after 30 minutes.To remove DPPH50% is that the required facial cream amount of IC50 is the non-oxidizability index.Clearance rate P calculates available following formula:
P＝[A
0-(A
i-A
j)]/A
0
A in the formula
0The absorbance of=2mL DPPH solution+2mL solvent; A
iThe absorbance of=2mL DPPH solution+2mL present embodiment facial cream extracting solution; A
jThe absorbance of=2mL present embodiment facial cream extracting solution+2mL solvent.
The result shows that (1 * 10-4mol/L) 50% is that the required Sargassum fusiforme (Harv.) Setch facial cream of IC50 amount is 0.9 gram to external removing DPPH free radical.Therefore facial cream provided by the present invention has outstanding external removing free radical ability, plays antioxidation and delaying decrepitude of skin function.
The anti-ultraviolet property test:
Get facial cream 5g through 5% CaCl2 aqueous solution breakdown of emulsion, add the 50ml water extraction after 1-2 hour, 4000 rev/mins centrifugal 10 minutes, filter, get the scanning of filtrate 200-700nm ultraviolet spectrometry photometry, the result has tangible uv absorption in the 250-400nm ultra-violet (UV) band, proves that fully this product can prevent the ultraviolet radiation function to a certain extent.
Claims (3)
1, a kind of multiple-effect washing cream is characterized in that comprising following component: (if no special instructions, the content of all components is mass percent)
Squalane 5-10%
Hexadecanol 2-5%
Liquid paraffin 10-15%
Tween-60 2-3%
Tristerin 2-3%
Glycerol 5-10%
Sargassum fusiforme (Harv.) Setch extract B 0-20%
Sargassum fusiforme (Harv.) Setch extract C 1.5-2.5%
Sargassum fusiforme (Harv.) Setch extract D 0.5-1.5%
Ascorbic acid 2-3%
Methyl parahydroxybenzoate 0.2-0.3%
Polyethylene Glycol 5-7%
Essential oil 0.01-0.05
The aquesterilisa surplus
Wherein, described Sargassum fusiforme (Harv.) Setch preparation method of extract is as follows:
At first prepare the Sargassum fusiforme (Harv.) Setch extract A: after using the clear water rinsing clean Sargassum fusiforme (Harv.) Setch,, cross 80 mesh sieves after pulverizer is pulverized and obtain dry powder 50-60 ℃ of oven dry; Dry powder was added flooding 2～3 hours, and wherein the mass ratio of dry powder and water is 1: 30-40; In the centrifugal sedimentation after 10-12 minute of 800-1200W ultrasonic Treatment, obtain supernatant one and precipitate one with ultrasound wave; Precipitate one water under 70-80 ℃ of temperature is carried 1-2 hour, the supernatant two of centrifugal sedimentation again and precipitate two; Precipitate dual-purpose 2% carbonic acid soda is carried 1-2 hour, with the centrifugal supernatant three that gets of method; Mixing supernatant one, two, three is also regulated its pH value to 7.0, concentrates in 0.1Mpa, 50-60 ℃ reduced vacuum and obtains concentrated solution; Concentrated solution is used the ethanol precipitation of volume fraction 65-70% then with Sevage method Deproteinization 2-4 time, and precipitate is used 1 successively: the acetone of 5-10, absolute ethanol washing, filtration obtain Sargassum fusiforme (Harv.) Setch extract A crude product with the precipitate vacuum decompression drying that obtains; Sargassum fusiforme (Harv.) Setch extract A crude product is used 1 successively: after the Rhizoma Zingiberis Recens of 6-10 went the granular active carbon absorption of raw meat, 1: 10-15, centrifugation obtained supernatant again, behind supernatant liquid filtering, use 2-5: the decolouring of 1AB-8 macroporous adsorbent resin, filter, get its filtrate, be the Sargassum fusiforme (Harv.) Setch extract A;
The preparation of Sargassum fusiforme (Harv.) Setch extract B: fresh Sargassum fusiforme (Harv.) Setch is clean with the clear water rinsing, dry then, pulverizing obtains dry powder B, with dry powder: water is 1: the ratio of 30-40 adds distilled water, 800-1200W supersound process 10-12 minute, lixiviate 2-4 hour in the time of 4 ℃ then, centrifugal precipitate and the supernatant of getting, drying precipitate, supernatant 6-15: after 1 Rhizoma Zingiberis Recens removes raw meat, reuse 10-15: 1 granular active carbon absorption, centrifugal sedimentation again is behind supernatant liquid filtering, liquid 4-10: 1 AB-8 macroporous adsorbent resin decolouring, filter and obtain the Sargassum fusiforme (Harv.) Setch extract B;
The Sargassum fusiforme (Harv.) Setch extract A is made with extra care, it is dissolved into 1% aqueous solution, DEAE-52 cellulose anion-exchange column, 2% sodium chloride eluting through liquid chromatography (LC) instrument Φ 2 * 40cm, merge to collect the detected polysaccharide liquid of sulphuric acid phynol method through 3500 molecular weight membrane distillation water dialysis desaltings, under 60 ℃, 0.1MPa, get the Sargassum fusiforme (Harv.) Setch extract C then in vacuum lyophilization;
The preparation method of Sargassum fusiforme (Harv.) Setch extract D is as follows: after using the clear water rinsing clean Sargassum fusiforme (Harv.) Setch, 50-60 ℃ of oven dry, pulverized the 80-100 mesh sieve then and obtain dry powder 10g; In dry powder, add 30-40mL ethanol chloroform water mixed solution dissolving (ethanol: chloroform: water=2: 1: 0.8), in 50-60 ℃ of water-bath, extract fatty acid, after extraction time is 2-3 hour, at room temperature left standstill 8-12 hour, centrifugal sedimentation is then got supernatant and is added 5: 2 chloroform extractions 2-3 time, and the collection chloroform layer is removed moisture content with anhydrous sodium sulfate drying, at 0.1Mpa, 50-60 ℃ of evaporative removal chloroform solvent, last inflated with nitrogen is dry must Sargassum fusiforme (Harv.) Setch extract D then.
2, multiple-effect washing cream according to claim 1 is characterized in that: centrifugal sedimentation speed is 4000-5000 rev/min in the preparation of described Sargassum fusiforme (Harv.) Setch extract, and centrifugation time is 10-12 minute.
3, a kind of preparation method of multiple-effect washing cream as claimed in claim 1 is characterized in that comprising the steps:
A) squalane of 5-10%, the paraffin oil of 10-15% and the Sargassum fusiforme (Harv.) Setch extract D mixing of 05-1.5% are obtained oil phase A, oil phase A is put into 70-80 ℃ of water-bath heating dissolve each other, 70-80 ℃ of insulation;
B) 1.5-2.5% Sargassum fusiforme (Harv.) Setch extract C, 5-10% glycerol and the mixing of 10-20% aquesterilisa are obtained aqueous phase B;
C) tristerin of 2-3% and the polysorbate60 of 2-3% are mixed into compound emulsifying agent 70-80 ℃ of water-bath;
D) with aqueous phase B after 70-80 ℃ of heating in water bath dissolves each other, compound emulsifying agent added wherein stir, then oil phase A is slowly added wherein, and is stirred to complete emulsifying;
E) add the Polyethylene Glycol of 5-7%, the hexadecanol of 2-5%, the essential oil of 0.01-0.05%, the methyl parahydroxybenzoate of 0.2-0.3%, slowly be cooled to below 40-50 ℃, and then add the aquesterilisa of the ascorbic acid of Sargassum fusiforme (Harv.) Setch extract B, 2-3% of 10-20% and 10-55% and stir, and put into colloid mill and fully pack behind the vacuum emulsification.
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