CN101234184A - Orally-administered Chinese medicine composition for treating radiation proctitis - Google Patents
Orally-administered Chinese medicine composition for treating radiation proctitis Download PDFInfo
- Publication number
- CN101234184A CN101234184A CNA2008100151063A CN200810015106A CN101234184A CN 101234184 A CN101234184 A CN 101234184A CN A2008100151063 A CNA2008100151063 A CN A2008100151063A CN 200810015106 A CN200810015106 A CN 200810015106A CN 101234184 A CN101234184 A CN 101234184A
- Authority
- CN
- China
- Prior art keywords
- radix
- herba
- chinese medicine
- blood
- catechu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a Chinese traditional medicine composition for oral administration to treat radiation proctitis, belonging to a field of Chinese traditional medicine. The raw medicinal materials comprising the effective components of the composition are prepared with the weight proportion as follows: 30-60g agrimony, 20-30g humulus scandens, 10-15g ginseng, 20-30g yam, 15-30g Coix seed, 15-30g hedyotis diffusa willd, 15-30g Garden Burnet, 6-10g cinnamon, 3-6g panax notoginseng, 10-15g allium macrostemon Bunge, 15-24g white peony root, 10-15g ebony, 10-15g catechu, 10-15g toasted hedgehog skin and 6-10g liquorice. All the materials are prepared to be soup for warm administration twice a day in the morning and in the afternoon. All the materials in the invention are compatible to play a role of invigorating spleen and kidney, clearing intestines and removing dampness, dispelling diarrhea and stopping diarrhea with a remarkable clinical curative effect, while at the same time, the composition adopts a pure Chinese traditional medicine preparation, which has a low incidence of adverse reactions.
Description
Technical field
The present invention relates to a kind of Chinese medicine, is a kind of Chinese medicine composition of orally taken for curing radiation rectitis specifically, belongs to the field of Chinese medicines.
Background technology
Radiation rectitis is to be secondary to common complication behind the pelvic malignant radiotherapy.In recent years, along with improving constantly of wild expansion of the carrying out of the popularizing of radiotherapy in the treatment, internal radiation, the increase of radiological dose, radiation and malignant tumor long term survival rate, the sickness rate of radiation rectitis constantly increases.Statistics shows: the sickness rate of radiation rectitis is 16.1%～42%, mainly shows as diarrhoea, bloody purulent stool, bearing down, and 3-20 was many times on 1st, and 2 months persistent period-4 year, the incidence rate of domestic report is higher than abroad.Radiation rectitis is in case take place, and promptly quality of life of patient produced to have a strong impact on, and not only influences absorption of nutrient ingredients and nutritional disorder takes place, and makes disease progression, even might cause patient death.At this complication, the doctor trained in Western medicine conventional therapy mainly adopt anti symptom treatment and nutrition supporting therapy, but curative effect is unsatisfactory at present, lacks certain therapy measure.
Summary of the invention
The objective of the invention is to overcome the deficiency of existing medicine, provide a kind for the treatment of both the principal and secondary aspects of a disease, anticancer antidiarrheal to develop simultaneously, can effectively remove the radiation rectitis clinical symptoms and improve the intestinal mucosa damage, the Chinese medicine preparation that untoward reaction is little, said preparation can be eliminated diarrhoea rapidly, and improve other clinical symptoms, improve patient's life quality.
Technical scheme of the present invention is: the Chinese medicine composition of this kind orally taken for curing radiation rectitis is characterized in that the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 30-60g, Herba humuli scandentis 20-30g, Radix Ginseng 10-15g, Rhizoma Dioscoreae 20-30g, Semen Coicis 15-30g, Herba Hedyotidis Diffusae 15-30g, Radix Sanguisorbae 15-30g, Cortex Cinnamomi 6-10g, Radix Notoginseng 3-6g, Bulbus Allii Macrostemonis 10-15g, Radix Paeoniae Alba 15-24g, Fructus Mume 10-15g, catechu 10-15g, process Corium Erinacei Seu Hemiechianus 10-15g, Radix Glycyrrhizae 6-10g.
Preparation and using method: take by weighing Herba Agrimoniae, Herba humuli scandentis, Radix Ginseng, Rhizoma Dioscoreae, Semen Coicis, Herba Hedyotidis Diffusae, Radix Sanguisorbae, Bulbus Allii Macrostemonis, the Radix Paeoniae Alba, Fructus Mume, catechu, process Corium Erinacei Seu Hemiechianus and Radix Glycyrrhizae adds cold water 600ml by said ratio, soaked 30 minutes, head fries in shallow oil 25 minutes (under behind the Cortex Cinnamomi), extracting juice 200ml; Add water 400ml again, continued to fry in shallow oil extracting juice 200ml 20 minutes.Radix Notoginseng is ground and is smalls, and the medicine juice that front and back are obtained for twice mixes that the back is divided early, evening 2 times is towards the Notoginseng Root decoction being taken warmly.
The further technical scheme of the present invention is: the Chinese medicine composition of this kind orally taken for curing radiation rectitis is characterized in that the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 30-60g, Herba humuli scandentis 25-30g, Radix Ginseng 10-15g, Rhizoma Dioscoreae 24-30g, Semen Coicis 20-30g, Herba Hedyotidis Diffusae 24-30g, Radix Sanguisorbae 20-30g, Cortex Cinnamomi 6-10g, Radix Notoginseng 3-6g, Bulbus Allii Macrostemonis 12-15g, Radix Paeoniae Alba 18-24g, Fructus Mume 12-15g, catechu 10-12g, process Corium Erinacei Seu Hemiechianus 10-12g, Radix Glycyrrhizae 6-10g.
Preparation and using method: take by weighing Herba Agrimoniae, Herba humuli scandentis, Radix Ginseng, Rhizoma Dioscoreae, Semen Coicis, Herba Hedyotidis Diffusae, Radix Sanguisorbae, Bulbus Allii Macrostemonis, the Radix Paeoniae Alba, Fructus Mume, catechu, process Corium Erinacei Seu Hemiechianus and Radix Glycyrrhizae adds cold water 600ml by said ratio, soaked 30 minutes, head fries in shallow oil 25 minutes (under behind the Cortex Cinnamomi), extracting juice 200ml; Add water 400ml again, continued to fry in shallow oil extracting juice 200ml 20 minutes.Radix Notoginseng is ground and is smalls, and the medicine juice that front and back are obtained for twice mixes that the back is divided early, evening 2 times is towards the Notoginseng Root decoction being taken warmly.
The further again technical scheme of the present invention is: the Chinese medicine composition of this kind orally taken for curing radiation rectitis is characterized in that the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 45g, Herba humuli scandentis 30g, Radix Ginseng 12g, Rhizoma Dioscoreae 30g, Semen Coicis 24g, Herba Hedyotidis Diffusae 30g, Radix Sanguisorbae 24g, Cortex Cinnamomi 10g, Radix Notoginseng 6g, Bulbus Allii Macrostemonis 12g, Radix Paeoniae Alba 20g, Fructus Mume 15g, catechu 10g, process Corium Erinacei Seu Hemiechianus 10g, Radix Glycyrrhizae 8g.
Preparation and using method: take by weighing Herba Agrimoniae, Herba humuli scandentis, Radix Ginseng, Rhizoma Dioscoreae, Semen Coicis, Herba Hedyotidis Diffusae, Radix Sanguisorbae, Bulbus Allii Macrostemonis, the Radix Paeoniae Alba, Fructus Mume, catechu, process Corium Erinacei Seu Hemiechianus and Radix Glycyrrhizae adds cold water 600ml by said ratio, soaked 30 minutes, head fries in shallow oil 25 minutes (under behind the Cortex Cinnamomi), extracting juice 200ml; Add water 400ml again, continued to fry in shallow oil extracting juice 200ml 20 minutes.Radix Notoginseng is ground and is smalls, and the medicine juice that front and back are obtained for twice mixes that the back is divided early, evening 2 times is towards the Notoginseng Root decoction being taken warmly.
The present invention is made up of pure Chinese medicine, and the used Chinese medicine of filling a prescription has following effect:
Herba Agrimoniae: bitter, puckery, sweet, flat; Return lung, liver, spleen, large intestine channel.Hemostasis and dysentery-stopping, detoxifcation parasite killing, tonify deficiency." the southern regions of the Yunnan Province book on Chinese herbal medicine " cloud Herba Agrimoniae is controlled: " with the passing of time red white dysentery." this product merit is apt to astringing to arrest bleeding, the dysentery relieving that detoxifies, treatment acute and chronic diarrhea, dysentery all have good effect.Modern pharmacological research proves: the Herba Agrimoniae water decoction has remarkable potentiation to tumor-bearing mice interleukin II activity, tumor-bearing mice spleen NKT (NK) cytoactive there is obvious potentiation, show that Herba Agrimoniae is to the tumor mice nonspecific immunity, especially the immune surveillance to tumor has potentiation, simultaneously, the Herba Agrimoniae decoct can strengthen the tumor mice erythrocyte immune and stick the tumor cell ability, improve erythrocyte immune promotion factor active in the serum, reduce the inhibitory action factor active.
Herba humuli scandentis: sweet, bitter, cold; Return kidney, lung, Liver Channel.Heat-clearing and toxic substances removing, promoting urination to remove dampness, antidiarrheal.This moral character is sweet cold, obeys the fraud that no bitter cold is upset one's stomach for a long time.The clinical cards such as pyretic stranguria, stranguria caused by urinary stone, diarrhoea, dysentery, pulmonary tuberculosis that are used for the treatment of.Modern pharmacological research proves: Herba humuli scandentis all has inhibitory action to antibacterials such as staphylococcus aureus, streptococcus pneumoniae, escherichia coli, bacillus pyocyaneus.
Radix Ginseng: sweet, little hardship, tepor; Return spleen, lung, the heart, kidney channel.Effect with strongly invigorating primordial QI, invigorating the spleen to benefit the lung, nourishing blood to promote the production of body fluid, kidney-reinforcing Yang-strengthening, the beneficial will of calming the nerves.This product QI invigorating is held concurrently can nourishing blood to promote the production of body fluid, clinical multisystem disease such as cardiovascular system, digestive system, blood system, hormonal system, nervous system, immune system and the tumor etc. of being widely used in.Clinical combined with chemotherapy, radiotherapy in the treatment tumor can improve curative effect, reduce the damage to body.Modern pharmacological research proves: this product energy enhancing human body immunity function; kill and wound cancerous cell and cancerous cell is reversed; its extract, glycoside and polysaccharide can alleviate the harm of radiation to hemopoietic system, particularly glycoside higher anti-radioactivity, can protect and stimulate hemopoietic function of bone marrow.
Rhizoma Dioscoreae: sweet, flat; Return lung, spleen, kidney channel.Spleen reinforcing is good for the stomach, and lung benefiting reinforces the kidney, YIN nourishing and the production of body fluid promoting.This product reinforcing both QI and YIN, not dry oiliness, can enriching spleen-QI again can strengthening the spleen the moon, and mend and hold concurrently puckeryly, be the good merchantable brand of invigorating spleen and reinforcing stomach, lung moistening kidney tonifying.Be usually used in diarrhea due to hypofunction of the spleen, cough with asthma, quench one's thirst, card such as leukorrhagia, bed-wetting.Modern pharmacological research proves: Rhizoma Dioscoreae is rich in polysaccharide, can stimulate or regulate functions of immune system, can suppress normal rat gastric emptying motion and intestinal progradation, and it is hyperfunction also obviously to resist the rat stomach bowel movement that the bitter cold purgatives medicine causes.
Semen Coicis: sweet, light, cold; This product gets final product invigorating spleen to remove dampness, again can clearing away heat and discharging pus, clinical be used for the treatment of have loose bowels, card such as acute appendicitis, lung abscess, verruca plana, uterus carcinoma, gastric cancer.Modern pharmacological research proves: Semen Coicis contains compositions such as Semen Coicis lactone, and cancerous cell is had inhibitory action.
Herba Hedyotidis Diffusae: bitter, sweet, cold; GUIXIN, lung, liver, large intestine channel.Heat-clearing and toxic substances removing, eliminating carbuncle is anticancer, and dampness removing is treating stranguria, antidiarrheal.Clinical acute appendicitis, pyretic stranguria, jaundice, dysentery and the treatment for cancer of being used for.Modern pharmacological research proves: this product has immunoregulation effect, and energy enhancing human body immunity power stimulates reticuloendothelial cell hyperplasia, strengthens the phagocyte vigor, strengthens the ability of leukocytes phagocytic antibacterial, strengthens the effect of serum sterilizing.The Herba Hedyotidis Diffusae element has inhibitory action to white mice ascites hepatoma carcinoma cell, S-180, and its contained triterpenes, Coumarins all have antitumor action.
Radix Sanguisorbae: bitter, sour, be slightly cold; Return liver, stomach, large intestine channel.Cooling blood for hemostasis, eliminating fire and detoxication.This product bitter cold is fallen, and walks the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, goes into blood system, but lets out clearly and only, and is puckery and do not stop up stagnantly, is the good merchantable brand of clearing away heat to stop bleeding.Be usually used in having blood in stool, card such as dysentery, metrorrhagia, burn and scald, sore and toxic.Modern pharmacological research proves: Radix Sanguisorbae is to inhibited to various bacteria such as dysentery bacterium, escherichia coli, bacillus pyocyaneus, staphylococcus aureuses.
Cortex Cinnamomi: the heart, sweet, heat; Return kidney, spleen, the heart, Liver Channel.It is supporing yang to mend fire, cold relieving pain relieving, promoting the flow of QI-blood by warming the meridian.Modern pharmacological research proves: Oleum Cinnamomi is the armaticity wind-dispelling prescription that is good for the stomach, and can promote the secretion of saliva and gastric juice, alleviates the intestinal spasmic pain.The diarrhoea that Cortex Cinnamomi extract causes the Oleum Ricini Folium Sennae shows inhibitory action in various degree, and drug-induced bowel dysfunction is had Accommodation.
Bulbus Allii Macrostemonis: hot, bitter, temperature; Return lung, the heart, stomach, large intestine channel.Activating YANG and eliminating stagnation, therapeutic method to keep the adverse QI flowing downwards intestinal stasis relieving.This product is warm in nature sliding sharp, and up assigning can declare to stop up to stagnate, fall turbid, the sharp large intestine of expectorant, disconnected dysentery, has better effects to removing the dysentery tenesmus." dietitian's heart mirror ": " control red white dysentery, with same meter food of cooking congee of Bulbus Allii Macrostemonis." the modern pharmacological research confirmation: Bulbus Allii Macrostemonis has inhibitory action to dysentery bacterium, staphylococcus aureus.
Fructus Mume: sour, puckery, temperature; Return liver, spleen, lung, large intestine channel.Effect with the astringing intestine to stop diarrhea of astringing the lung, easing the stomach to subdue the ascarids, astringing to arrest bleeding.Be usually used in treating chronic cough of deficiency lung, chronic diarrhea chronic dysentery, abdominal pain due to worm stagnation, quench one's thirst, have blood in stool, card such as metrorrhagia." Handbook of Prescriptions for Emergencies " treatment chronic dysentery is more than, intestinal is dirty goes out, single with this product side of being.Modern pharmacological research confirms: Fructus Mume all has significant antibacterial action to staphylococcus, bacillus pyocyaneus, multiple enteral pathogenic bacterium.
The Radix Paeoniae Alba: acid, bitter, sweet is slightly cold; Return liver, spleen, lung, large intestine channel.The yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, suppressing liver-YANG.The spontaneous perspiration and the night sweat that are usually used in deficiency of liver-blood, menoxenia, stomachache, diarrhoea, dysentery and disharmony of nutrient QI with defensive QI.Modern pharmacological research confirms:: have calmness, spasmolytic, antiulcer, blood vessel dilating, antibiotic, bringing down a fever, ease pain reaches stronger antiinflammatory action.
Radix Notoginseng: sweet, little hardship, temperature; Return liver, kidney channel.Removing stasis to stop bleeding, reducing swelling and alleviating pain.This product has hemostasis and does not stay the stasis of blood, and the not characteristics of removing blood stasis of invigorating blood circulation are the good medicine of inside and outside blood trouble card.Clinical be used for traumatic injury, the stasis of blood stagnate swell and ache, cards such as skin infection swells and ache, inside and outside blood trouble card, the thoracic obstruction." Records of Tradition Chinese and Western Medicine in Combination " joins crow egg-shaped thing treatment with it, and " the dysentery hematochezia is scarlet does not heal for a long time, rots in the intestinal, soaks into ulcer." modern pharmacological research confirms: this product has effects such as antiinflammatory, analgesia, hemostasis, anticoagulant, anticancer, human body immunity improving power.
Catechu: bitter, puckery, cool; GUIXIN, lung meridian.Removing heat-phlegm, hemostasis antidiarrheal, promoting granulation and relieving pain, removing dampness is held back skin ulcer.Modern pharmacological research confirms: this product has effects such as convergence, antidiarrheal, antibacterial, anticancer, hemostasis.
Process Corium Erinacei Seu Hemiechianus: bitter, puckery, flat; Go into stomach, large intestine channel.Promoting the circulation of QI to relieve pain, controlling nocturnal emission with astringent drugs reducing urination, removing stasis to stop bleeding." god side, longevity territory " cloud: " hedgehog skin ashing, the wine clothes are controlled multicolored dysentery." the bright all olds docter of TCM of Liu with the treatment ulcerative colitis, think that this product returns large intestine channel, the effect of the through sick institute of the efficacy of a drug of leading is arranged.
Radix Glycyrrhizae: sweet, flat; Return spleen, stomach, the heart, lung meridian.Heat-clearing and toxic substances removing, invigorating the spleen and replenishing QI, relieving spasm to stop pain, expelling phlegm for arresting cough, the mediation property of medicine.This product is longer than the invigorating middle warmer emergency, is usually used in deficiency of spleen-QI and stomach-QI, sore swollen toxin, the anxious pain of contraction and the property of medicine that is in harmonious proportion.Studies confirm that: Radix Glycyrrhizae has the effect of adrenocortical hormone sample, detoxifcation is arranged, eliminates the phlegm, antitussive effect, and antiulcer, spasmolytic, analgesia, hepatoprotective, antiinflammatory, effect such as anticancer are arranged.
The present invention has following beneficial effect:
1, effectively improve clinical symptoms: generally took medicine 5 days, patient's stomachache, diarrhoea, stool containing pus and blood are clearly better, and ordinary circumstance is improved.
2, radiation rectitis is had obvious curative effects: radiation rectitis patient 50 examples are observed in treatment, took medicine 20 days, and clinical recovery 33 examples (66%), 13 examples that take a turn for the better (26%), invalid 4 examples (8%), total effective rate is up to 92%.
3, improve patient body quality, human body immunity improving power, enhancing body resistance.
4, pure Chinese medicinal preparation, adverse reaction rate is low.This organizes 50 routine patients, has 1 example to take medicine and slight abdominal distention afterwards occurs, adds with Fructus Aurantii (parched) and goes into decoct, and abdominal distention disappears.
Modern medicine is thought: RADI is the important paathogenic factor of radiation rectitis, and its morbidity is closely related with radiological dose.In tumor of pelvic cavity radiotherapy process, will shine rectum inevitably, and mucous membrane of rectum is very responsive to lonizing radiation, makes regeneration of damaged, the blood capillary of intestinal superficial epithelium cell ooze out and influence mucosal barrier function, thereby be directly exposed under the bacterial action, cause the generation of radiation rectitis.Its morbidity is closely related with radiological dose.In general, intraperitoneal irradiation accumulated dose is seldom fallen ill the following person of 30Gy; Accumulated dose is when 50Gy, and radiation rectitis can take place about 8% patient; If the radiotherapy accumulated dose is more than 70Gy, the radiation rectitis incidence rate is up to 36%.Radiation rectitis belongs to Chinese medicine " intestinal Bleach ", " chronic dysentery ", " dysentery " category.The traditional Chinese medical science is thought: RADI is that specific burning hot malicious heresy is trouble, easily consumes the moon of feeling frustrated; The main etiology and pathogenesis of radiation rectitis is: healthy energy is lost empty, burning hot poison evil (ray) invasion and attack, and transporting and transforming function of the spleen and stomach is not normal, intestinal mansion conduction mistake department, damp-heat accumulation intestinal mansion, with the QI and blood knot of fighting mutually, so that intestinal mansion adipose membrane blood network is impaired, the diarrhea pus and blood; With the passing of time undermine the kidney yin kidney yang, touching difficulty more.Primary disease is the card of simulataneous insufficiency and excessive, and strengthening vital QI to eliminate pathogenic factors is answered in treatment, unavailable bitter cold, damage gastric qi.At the etiology and pathogenesis of primary disease, this side sets upright tonify deficiency, hemostasis with Herba Agrimoniae and removes dysentery, and Herba humuli scandentis clearing away heat-damp and promoting diuresis, the antidiarrheal dysentery clearind deficient heat of holding concurrently is monarch drug altogether; Be aided with Radix Ginseng, Rhizoma Dioscoreae, Semen Coicis invigorating the spleen to clear away damp pathogen, the antidiarrheal of reinforcing the kidney, Herba Hedyotidis Diffusae, Radix Sanguisorbae removing toxicity for eliminating carbuncles, eliminating pathogenic heat from blood to cure dysentery are ministerial drug altogether; Assistant is held back liver antidiarrheal with Fructus Mume, the fire of Cortex Cinnamomi kidney tonifying is sought cold expelling and winter protection medicine of a cold nature thing damage gastric qi with warming the spleen sun, temperature, Bulbus Allii Macrostemonis therapeutic method to keep the adverse QI flowing downwards intestinal stasis relieving and remove tenesmus, Radix Paeoniae Alba easing the affected liver emergency and the stomachache of ending, Radix Notoginseng, catechu removing stasis to stop bleeding, reducing swelling and alleviating pain, removing dampness are held back skin ulcer, processing that the Corium Erinacei Seu Hemiechianus blood stasis dispelling is logical to stagnate, lead the efficacy of a drug intestinal mansion of going directly, is adjuvant drug altogether; Make with Radix Glycyrrhizae and middle emergency, coordinating the actions of various ingredients in a prescription.All medicine compatibilities are set upright and do not held back heresy, and are eliminating evil and just do not hinder, and play tonifying speen and tonifying kidney altogether, the bowel relieving dampness removing, and expelling pus and promoting granulation removes the effect of rushing down dysentery relieving.
Model case is as follows:
1, Wang, woman, 76 years old, first visit on August 25 in 2002.Main suit: stomachache, stool mucus, pus and blood 4 months.Patient's cause half a year is suffered from cervical cancer at Liaocheng City hospital row radiotherapy, treat 1 course of treatment (in 7 weeks, accumulated dose is 70Gy) after, occur that low grade fever is weak, left lower abdomen pain, defecate mucus, pus and blood.In this institute's per rectum spectroscopy, be diagnosed as radiation rectitis, through transfusion and the treatment of oral Chinese and western drugs, the state of an illness does not have obvious improvement.Examine and see: emaciated physique, low grade fever, spiritlessness and weakness is defecated 5-6 time on the one, is mingled with mucus, pus and blood, even blood, and tenesmus is vexedly slept less, the oliguria yellow skin, red tongue, tongue are few and dried, thready and rapid pulse.Dialectical: deficiency of qi and yin, accumulate damage intestinal network in the pyretic toxicity.Method of treatment: supplementing QI and nourishing YIN, clearing away heat and cooling blood, detoxifcation dysentery relieving.Give medicine of the present invention.Took medicine 5 days, low grade fever moves back, and stomachache, tenesmus obviously alleviate, and stool containing pus and blood disappears, idol band mucus, 2-3 time on the one.Continue and obey 15 doses of tops, all cards of patient disappear.Followed up a case by regular visits to 2 months, and do not see recurrence.
2, Korea Spro, man, 72 years old, 2002.11.18 first visit.Main suit: stomachache, tenesmus, stool mucus, pus and blood 3 months.Before the patient 5 months, accept radiotherapy in Shandong Province hospital because of postoperative rectal cancer, treated for 3 weeks after, stomachache, tenesmus, diarrhoea appear, stool mucus, pus and blood, 4-5 time on the one.The per rectum spectroscopy is diagnosed as radiation rectitis.Hospitalization one month, the state of an illness are not seen obvious improvement.Examine and see: emaciated physique, shallow complexion is rushed down when half congealed during stool, is mingled with mucus, blood, aqueous-grainy diarrhea is arranged, and body of the tongue is light red, root of the tongue portion greasy fur, soft and rapid pulse.Dialectical: weakness of the spleen and stomach, retention of damp-heat in the interior.Method of treatment: invigorating the spleen and benefiting QI, bowel relieving removing dampness.Give medicine of the present invention, took medicine 7 days, patient's disappearance of suffering from abdominal pain, it is rare soft to defecate, no mucus and blood, 1-2 time on the one.Continue and obey 12 doses of tops, all cards of patient disappear.Followed up a case by regular visits to 3 months, and do not see recurrence.
3, Lee, woman, 55 years old, 2003.3.5 first visit.Main suit: stomachache, tenesmus, stool containing pus and blood half a year.The patient accepted radiotherapy because of rectal cancer in Liaocheng City hospital before 1 year, treat 1 course of treatment (in 7 weeks, accumulated dose is 60Gy) after, occur to feel sick, appetite descends, stomachache, tenesmus, stool containing pus and blood, 6-7 time on the one.The per rectum spectroscopy is diagnosed as radiation rectitis, and through hospitalization one month, the patient felt sick and disappears, and the food of receiving takes a turn for the better, and other symptoms are not seen obvious improvement.Though after this multi-treatment is not all cured.Examine and see: emaciated physique, fatigue and asthenia, distention and pain in the lower abdomen just rushes down not freely, is mingled with mucus or mulberry blood, and 5-6 time on the one, pain in the abdomen is heavy, and there is petechiae on dimly red tongue, limit, root of the tongue portion yellow and greasy fur, thready and hesitant pulse.Dialectical: healthy energy is lost empty, retention of damp-heat in the interior, qi stagnation blood stasis.Method of treatment: setting upright silt, the accent intestinal of regulating the flow of vital energy, clearing away heat and eliminating dampness.Give medicine of the present invention, take medicine 10 doses, fatigue and asthenia, stomachache, tenesmus obviously alleviate, and stool is kept to 2-3 time on the one, idol band mucus.Continue and obey 20 doses of tops, patient's disease disappears.Follow up a case by regular visits to half a year, do not see recurrence.
4, Xing, man, 62 years old, 2004.7.18 month first visit.The main suit: stomachache, tenesmus, stool containing pus and blood are surplus half a year.The patient accepted radiotherapy because of postoperative rectal cancer before 7 months, treat 1 course of treatment (in 5 weeks, accumulated dose is 50Gy) after, umbilicus week stomachache, tenesmus, stool containing pus and blood appear in the patient, 4-6 time on the one, are diagnosed as radiation rectitis, though through multi-treatment, tenesmus, stool containing pus and blood be outbreak repeatedly still.Examine and see: emaciated physique, fatigue and asthenia, tenesmus, stool containing pus and blood has a small amount of mucus, and continuous and dull pain in the abdomen is liked warm pain relieved by pressing, light, the moist fur of tongue fur, deep-thready pulse.Dialectical: as to contain in the deficiency of spleen and stomach, damp.Method of treatment: warming the kidney and strengthening the spleen, yang invigorating dehumidifying, relieving diarrhea with astringents.Give medicine of the present invention, take medicine 7 doses, tenesmus, stool containing pus and blood obviously alleviate, and 2-3 time on the one, fatigue and asthenia, stomachache are improved, and the food of receiving increases.Continue 15 doses of clothes tops, all cards disappear, and give 10 doses of tops, the next day 1 dose, after treatment.Follow up a case by regular visits to half a year, do not see recurrence.
5, Lee, man, 68 years old, first visit in 20054.12 months.Main suit's stomachache, diarrhoea 2 months.The patient before 5 months because of postoperative rectal cancer at Liaocheng City hospital row radiotherapy, treat 1 course of treatment (in 5 weeks, accumulated dose is 50Gy) after, occur to feel sick, poor appetite, stomachache, diarrhoea.The per rectum spectroscopy is diagnosed as radiation rectitis, and through the infusion treatment two weeks, diet increases, and feeling sick disappears, but suffers from abdominal pain, suffers from diarrhoea and do not see obvious improvement.Examine and see, stomachache, tenesmus, stool is mingled with that a large amount of whites are sticking freezes in the pasty state, and dysentery is not smooth, and 4-6 time on the one, companion's abdominal distention, the yellow skin of urinating, soft and rapid pulse.Dialectical: damp and hot delay, functional activity of QI being not smooth.Method of treatment: spleen invigorating helps fortune, and the regulating QI machine is dredged in the bowel relieving removing dampness.Give medicine of the present invention, take medicine 7 doses, patient's stomachache, abdominal distention, tenesmus obviously alleviates, and defecates sticking the freezing of idol band white 1-2 time on the one.Continue and obey 10 doses of tops, all cards disappear.Followed up a case by regular visits to 2 months, and do not see recurrence.
6, permitted certain, woman, 62 years old, 2006.7.15. month first visit.Main suit: stomachache, diarrhea mucus, bloody purulent stool 4 months.The patient because of suffering from cervical cancer at Liaocheng City hospital row radiotherapy, treated 1 (the 7 week course of treatment before half a year, accumulated dose is 70Gy) after, fatigue and asthenia, appetite minimizing appear, tenesmus, diarrhea mucus, bloody purulent stool 7-8 time on the one, are diagnosed as radiation rectitis.Through hospitalization 1 month, conditions of patients was not seen obvious improvement.Examine and see: fatigue and asthenia, bitter taste and dryness in the mouth, the red white pus and blood of diarrhea, thickness such as jelly, 5-6 time on the one, tenesmus, burning sensation of the anus, yellowish or reddish urine, red tongue, yellow and greasy fur, slippery and rapid pulse.Dialectical: weakness of the spleen and stomach, the damp and hot intestinal that accumulates, damage adipose membrane intestinal network.Method of treatment: clearing away heat and eliminating dampness, regulating QIization stagnates.Give medicine of the present invention, take medicine 7 doses, patient's stomachache, diarrhea mucus, bloody purulent stool obviously alleviate, and defecate sticking the freezing of idol band white 1-2 time on the one.Continue and obey 10 doses of tops, all cards disappear.Followed up a case by regular visits to 2 months, and do not see recurrence.
The specific embodiment
Example one: a kind of Chinese medicine composition of orally taken for curing radiation rectitis, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 30g, Herba humuli scandentis 20g, Radix Ginseng 10g, Rhizoma Dioscoreae 20g, Semen Coicis 15g, Herba Hedyotidis Diffusae 15g, Radix Sanguisorbae 15g, Cortex Cinnamomi 6g, Radix Notoginseng 3g, Bulbus Allii Macrostemonis 10g, Radix Paeoniae Alba 15g, Fructus Mume 10g, catechu 10g processs Corium Erinacei Seu Hemiechianus 10g, Radix Glycyrrhizae 6g.
Preparation and using method: take by weighing Herba Agrimoniae, Herba humuli scandentis, Radix Ginseng, Rhizoma Dioscoreae, Semen Coicis, Herba Hedyotidis Diffusae, Radix Sanguisorbae, Bulbus Allii Macrostemonis, the Radix Paeoniae Alba, Fructus Mume, catechu, process Corium Erinacei Seu Hemiechianus and Radix Glycyrrhizae by said ratio, add cold water 600ml, soaked 30 minutes, head fries in shallow oil 25 minutes (under behind the Cortex Cinnamomi), extracting juice 200ml; Add water 400ml again, continued to fry in shallow oil extracting juice 200ml 20 minutes.Radix Notoginseng is ground and is smalls, after the medicine juice that front and back are obtained for twice mixes, divides early, evening 2 times is towards the Notoginseng Root decoction being taken warmly.
Example two: a kind of Chinese medicine composition of orally taken for curing radiation rectitis, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 60g, Herba humuli scandentis 30g, Radix Ginseng 15g, Rhizoma Dioscoreae 30g, Semen Coicis 30g, Herba Hedyotidis Diffusae 30g, Radix Sanguisorbae 30g, Cortex Cinnamomi 10g, Radix Notoginseng 6g, Bulbus Allii Macrostemonis 15g, Radix Paeoniae Alba 24g, Fructus Mume 15g, catechu 15g processs Corium Erinacei Seu Hemiechianus 15g, Radix Glycyrrhizae 10g.
Preparation and using method: with example one.
Example three: a kind of Chinese medicine composition of orally taken for curing radiation rectitis, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 30g, Herba humuli scandentis 25g, Radix Ginseng 10g, Rhizoma Dioscoreae 24g, Semen Coicis 20g, Herba Hedyotidis Diffusae 24g, Radix Sanguisorbae 20g, Cortex Cinnamomi 6g, Radix Notoginseng 3g, Bulbus Allii Macrostemonis 12g, Radix Paeoniae Alba 18g, Fructus Mume 12g, catechu 10g processs Corium Erinacei Seu Hemiechianus 10g, Radix Glycyrrhizae 6g.
Preparation and using method: with example one.
Example four: a kind of Chinese medicine composition of orally taken for curing radiation rectitis, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 60g, Herba humuli scandentis 30g, Radix Ginseng 15g, Rhizoma Dioscoreae 30g, Semen Coicis 30g, Herba Hedyotidis Diffusae 30g, Radix Sanguisorbae 30g, Cortex Cinnamomi 10g, Radix Notoginseng 6g, Bulbus Allii Macrostemonis 15g, Radix Paeoniae Alba 24g, Fructus Mume 15g, catechu 12g processs Corium Erinacei Seu Hemiechianus 12g, Radix Glycyrrhizae 10g.
Preparation and using method: with example one.
Example five: a kind of Chinese medicine composition of orally taken for curing radiation rectitis, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 45g, Herba humuli scandentis 30g, Radix Ginseng 12g, Rhizoma Dioscoreae 30g, Semen Coicis 24g, Herba Hedyotidis Diffusae 30g, Radix Sanguisorbae 24g, Cortex Cinnamomi 10g, Radix Notoginseng 6g, Bulbus Allii Macrostemonis 12g, Radix Paeoniae Alba 20g, Fructus Mume 15g, catechu 10g processs Corium Erinacei Seu Hemiechianus 10g, Radix Glycyrrhizae 8g.
Preparation and using method: with example one.
Example six: a kind of Chinese medicine composition of orally taken for curing radiation rectitis, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 45g, Herba humuli scandentis 25g, Radix Ginseng 10g, Rhizoma Dioscoreae 24g, Semen Coicis 24g, Herba Hedyotidis Diffusae 24g, Radix Sanguisorbae 27g, Cortex Cinnamomi 10g, Radix Notoginseng 5g, Bulbus Allii Macrostemonis 15g, Radix Paeoniae Alba 24g, Fructus Mume 15g, catechu 12g processs Corium Erinacei Seu Hemiechianus 12g, Radix Glycyrrhizae 8g.
Preparation and using method: with example one.
Example seven: a kind of Chinese medicine composition of orally taken for curing radiation rectitis, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 30g, Herba humuli scandentis 26g, Radix Ginseng 10g, Rhizoma Dioscoreae 24g, Semen Coicis 20g, Herba Hedyotidis Diffusae 25g, Radix Sanguisorbae 20g, Cortex Cinnamomi 6g, Radix Notoginseng 3g, Bulbus Allii Macrostemonis 12g, Radix Paeoniae Alba 18g, Fructus Mume 12g, catechu 10g processs Corium Erinacei Seu Hemiechianus 10g, Radix Glycyrrhizae 6g.
Preparation and using method: with example one.
Example eight: a kind of Chinese medicine composition of orally taken for curing radiation rectitis, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 45g, Herba humuli scandentis 30g, Radix Ginseng 12g, Rhizoma Dioscoreae 30g, Semen Coicis 24g, Herba Hedyotidis Diffusae 30g, Radix Sanguisorbae 24g, Cortex Cinnamomi 10g, Radix Notoginseng 6g, Bulbus Allii Macrostemonis 12g, Radix Paeoniae Alba 20g, Fructus Mume 15g, catechu 10g processs Corium Erinacei Seu Hemiechianus 10g, Radix Glycyrrhizae 8g.
Preparation and using method: with example one.
Example nine: a kind of Chinese medicine composition of orally taken for curing radiation rectitis, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 48g, Herba humuli scandentis 27g, Radix Ginseng 10g, Rhizoma Dioscoreae 30g, Semen Coicis 27g, Herba Hedyotidis Diffusae 30g, Radix Sanguisorbae 27g, Cortex Cinnamomi 7g, Radix Notoginseng 4g, Bulbus Allii Macrostemonis 13g, Radix Paeoniae Alba 21g, Fructus Mume 14g, catechu 10g processs Corium Erinacei Seu Hemiechianus 12g, Radix Glycyrrhizae 7g.
Preparation and using method: with example one.
Claims (3)
1, a kind of Chinese medicine composition of orally taken for curing radiation rectitis is characterized in that, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 30-60g, Herba humuli scandentis 20-30g, Radix Ginseng 10-15g, Rhizoma Dioscoreae 20-30g, Semen Coicis 15-30g, Herba Hedyotidis Diffusae 15-30g, Radix Sanguisorbae 15-30g, Cortex Cinnamomi 6-10g, Radix Notoginseng 3-6g, Bulbus Allii Macrostemonis 10-15g, Radix Paeoniae Alba 15-24g, Fructus Mume 10-15g, catechu 10-15g, process Corium Erinacei Seu Hemiechianus 10-15g, Radix Glycyrrhizae 6-10g.
2, the Chinese medicine composition of a kind of orally taken for curing radiation rectitis according to claim 1 is characterized in that, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 30-60g, Herba humuli scandentis 25-30g, Radix Ginseng 10-15g, Rhizoma Dioscoreae 24-30g, Semen Coicis 20-30g, Herba Hedyotidis Diffusae 24-30g, Radix Sanguisorbae 20-30g, Cortex Cinnamomi 6-10g, Radix Notoginseng 3-6g, Bulbus Allii Macrostemonis 12-15g, Radix Paeoniae Alba 18-24g, Fructus Mume 12-15g, catechu 10-12g, process Corium Erinacei Seu Hemiechianus 10-12g, Radix Glycyrrhizae 6-10g.
3, the Chinese medicine composition of a kind of orally taken for curing radiation rectitis according to claim 1 is characterized in that, the crude drug of forming active ingredient by following weight proportion is: Herba Agrimoniae 45g, Herba humuli scandentis 30g, Radix Ginseng 12g, Rhizoma Dioscoreae 30g, Semen Coicis 24g, Herba Hedyotidis Diffusae 30g, Radix Sanguisorbae 24g, Cortex Cinnamomi 10g, Radix Notoginseng 6g, Bulbus Allii Macrostemonis 12g, Radix Paeoniae Alba 20g, Fructus Mume 15g, catechu 10g, process Corium Erinacei Seu Hemiechianus 10g, Radix Glycyrrhizae 8g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100151063A CN101234184B (en) | 2008-03-06 | 2008-03-06 | Orally-administered Chinese medicine composition for treating radiation proctitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100151063A CN101234184B (en) | 2008-03-06 | 2008-03-06 | Orally-administered Chinese medicine composition for treating radiation proctitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101234184A true CN101234184A (en) | 2008-08-06 |
| CN101234184B CN101234184B (en) | 2010-09-08 |
Family
ID=39918251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008100151063A Expired - Fee Related CN101234184B (en) | 2008-03-06 | 2008-03-06 | Orally-administered Chinese medicine composition for treating radiation proctitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101234184B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102512624A (en) * | 2011-11-28 | 2012-06-27 | 李守玮 | Chinese medicine soup with functions of dispelling flatulence and strengthening stomach for treating functional dyspepsia |
| CN102657807A (en) * | 2012-04-24 | 2012-09-12 | 肖玉芹 | Chinese medicinal composition for treating radiation proctitis |
| CN103127317A (en) * | 2013-01-17 | 2013-06-05 | 田洪蕾 | Enema for treating radiation proctitis |
| CN104623419A (en) * | 2015-02-26 | 2015-05-20 | 王燕 | Traditional Chinese medicine preparation for treating proctitis and preparation of traditional Chinese medicine preparation |
-
2008
- 2008-03-06 CN CN2008100151063A patent/CN101234184B/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102512624A (en) * | 2011-11-28 | 2012-06-27 | 李守玮 | Chinese medicine soup with functions of dispelling flatulence and strengthening stomach for treating functional dyspepsia |
| CN102657807A (en) * | 2012-04-24 | 2012-09-12 | 肖玉芹 | Chinese medicinal composition for treating radiation proctitis |
| CN102657807B (en) * | 2012-04-24 | 2014-04-16 | 肖玉芹 | Chinese medicinal composition for treating radiation proctitis |
| CN103127317A (en) * | 2013-01-17 | 2013-06-05 | 田洪蕾 | Enema for treating radiation proctitis |
| CN103127317B (en) * | 2013-01-17 | 2014-07-30 | 田洪蕾 | Enema for treating radiation proctitis |
| CN104623419A (en) * | 2015-02-26 | 2015-05-20 | 王燕 | Traditional Chinese medicine preparation for treating proctitis and preparation of traditional Chinese medicine preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101234184B (en) | 2010-09-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102048894B (en) | Traditional Chinese medicine composition for treating burn and preparation method thereof | |
| CN103099959B (en) | Traditional Chinese medicine preparation for treating ulcerative colitis and preparation method thereof | |
| CN102205107B (en) | Chinese medicinal preparation for treating duodenal ulcer and preparation method thereof | |
| CN100493598C (en) | Oral Chinese traditional medicine composition for treating chronic enteritis | |
| CN102961648B (en) | Traditional Chinese medicine compound preparation for treating advanced colorectal cancer | |
| CN101422579B (en) | Traditional Chinese medicine preparation for treating oral ulcer | |
| CN102772781B (en) | Traditional Chinese medicine preparation for treating chronic colitis and preparation method thereof | |
| CN104225441A (en) | Traditional Chinese medicine composition for treating stomach trouble and preparation method of granules and capsules of traditional Chinese medicine composition | |
| CN101961480A (en) | Traditional Chinese medicinal composition for treating hematochezia and preparation method thereof | |
| CN103041256B (en) | Chinese herb preparation for curing recurrent respiratory tract infection of children | |
| CN104258289A (en) | Traditional Chinese medicine for treating enteritis | |
| CN104189783A (en) | Traditional Chinese medicine for treating oral ulcer | |
| CN101234184B (en) | Orally-administered Chinese medicine composition for treating radiation proctitis | |
| CN101085328A (en) | Oral administration traditional Chinese medicine composition for curing chronic gastritis | |
| CN103169883B (en) | Traditional Chinese medicine for treating infantile jaundice | |
| CN103055111B (en) | Traditional Chinese medicine composition for treating children's infantile malnutrition and preparation method thereof | |
| CN110339276A (en) | Traditional Chinese medicine for treating digestive tract tumor and preparation method thereof | |
| CN103223024A (en) | Diabetes mellitus dialectical traditional Chinese medicine prescription | |
| CN102861292B (en) | Medicament for treating esophageal cancer and preparation method thereof | |
| CN105833115A (en) | Traditional Chinese medicine for treating precancerous lesions of gastric cancer | |
| CN105749172A (en) | Medicament for treating gastric calculus and preparation thereof | |
| CN108904746A (en) | A kind of Chinese medicine composition and its preparation method and application for treating ulcerative colitis | |
| CN104436098A (en) | Traditional Chinese medicine preparation for treating multiple intestinal polyps | |
| CN108042744A (en) | A kind of Chinese medicine composition and preparation method for being used to treat prostatic disorders | |
| CN103520341A (en) | Traditional Chinese medicine prescription used for treating esophageal cancer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100908 Termination date: 20110306 |