CN102512624A

CN102512624A - Chinese medicine soup with functions of dispelling flatulence and strengthening stomach for treating functional dyspepsia

Info

Publication number: CN102512624A
Application number: CN2011104047910A
Authority: CN
Inventors: 李守玮
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-11-28
Filing date: 2011-11-28
Publication date: 2012-06-27
Anticipated expiration: 2031-11-28
Also published as: CN102512624B

Abstract

The invention discloses a Chinese medicine soup with the functions of dispelling flatulence and strengthening stomach for treating functional dyspepsia. The functional dyspepsia belongs to the category of diseases of spleen-stomach of Chinese medical science, such as stomachache, chronic atrophic gastritis, and vomit, the basic pathogenesis comprises spleen deficiency and dyspepsia, abnormal rising and falling of qi, thus the rules of treatment can be warming stomach and invigorating spleen and strengthening middle warmer and benefiting qi. The Chinese medicine soup with the functions of dispelling flatulence and strengthening stomach is prepared by selecting ginseng, Fructus jujubae, range peel, Rhizoma Cyperi, Radix Cureumae, Semen raphani, Semen Platycladi, Citron, and Allium macrostemon in our preparation department for patients. Clinical research shows that the total effective rate reaches 96.2 % and is obviously better than control groups, and the treatment cost is low, the side effect is low, and the Chinese medicine soup deserves to be clinically broadened.

Description

A kind of Chinese medicine of treating functional dyspepsia soup that is good for the stomach that expands of dispelling

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation of treating functional dyspepsia.

Background technology

Functional dyspepsia be meant persistence or intermittent attack with upper abdominal pain, big belly, early full, belch, inappetence, feel sick, vomiting etc. is main clinic symptoms; And one group of clinical syndrome can not explaining with the change of organic disease or anatomical structure; Be modal clinically a kind of functional gastrointestinal disorder, have a strong impact on patient's quality of life.The sickness rate of primary disease is higher, and according to bibliographical information, the prevalence of countries in the world is 20%～49%; China's FD patient's number accounts for 11% of general out patient service patient number, accounts for Gastroenterology Clinic patient's 53%.Up to now, western modern medicine mainly is empirical symptomatic treatment to this, does not still have satisfactory effect.

Summary of the invention

The purpose of this invention is to provide the dyspeptic Chinese medicine of a kind of treatment functions property soup that is good for the stomach that expands of dispelling.Functional dyspepsia belongs to the category of diseases of spleen-stomach such as motherland's medical science " stomachache ", " stomach painful abdominal mass ", " vomiting ".Diseased region is at gastral cavilty, and the pathological changes internal organs are spleen, stomach, liver.Insufficiency of the spleen dyspepsia, up-down mistake department are its basic pathogenesis.Should be the rule of treatment with stomach function regulating spleen invigorating, invigorating the spleen and replenishing QI.

The objective of the invention is to realize that the dispel bloated soup that is good for the stomach of the Chinese medicine of this treatment functional dyspepsia is processed by following parts by weight of Chinese traditional medicine: Radix Ginseng 15-25 part, Fructus Jujubae 10-20 part, Pericarpium Citri tangerinae 9-13 part, Rhizoma Cyperi 10-15 part, Radix Curcumae 10-15 part, Semen Raphani 9-13 part, Semen Platycladi 15-20 part, Fructus Citri 15-20 part, Bulbus Allii Macrostemonis 10-15 part through following technical scheme.

Preferably, dispel the expand soup that is good for the stomach of the Chinese medicine of this treatment functional dyspepsia is processed by following parts by weight of Chinese traditional medicine: 20 parts of Radix Ginsengs, 15 parts in Fructus Jujubae, 11 parts of Pericarpium Citri tangerinaes, 12 parts of Rhizoma Cyperis, 12 parts of Radix Curcumaes, 11 parts of Semen Raphanis, 17 parts of Semen Platycladi, 17 parts of Fructus Citris, 12 parts of Bulbus Allii Macrostemonis.

Radix Ginseng, strongly invigorating primordial QI in the side, invigorating the spleen to benefit the lung, promoting the production of body fluid and inducing sedation of the mind; Fructus Jujubae invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind relax the property of medicine; The Pericarpium Citri tangerinae regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; The Rhizoma Cyperi depressed liver-energy dispersing and QI regulating, menstruction regulating and pain relieving; The pain relieving of Radix Curcumae blood-activating and qi-promoting, the resolving depression mood; Semen Raphani helps digestion to remove and expands lowering the adverse-rising QI to resolve phlegm; The Semen Platycladi tranquilizing by nourishing the heart moistens just unimpeded; The Fructus Citri dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach;

The Bulbus Allii Macrostemonis activating YANG and eliminating stagnation, the circulation of qi promoting intestinal stasis relieving.All medicine phases 5 are played invigorating the spleen and benefiting QI, sending down the abnormal ascending QI altogether except that bloated merit.

Clinical data

1, two groups of cases of physical data are the court's outpatient service and inpatient.Treatment is organized in 130 examples, male 69 examples, women 61 examples, 21～60 years old age, average 43.5 years old, the course of disease 3 months～20 years, average 1.6 years; In matched group 120 examples, male 65 examples, women 55 examples, 20～59 years old age, average 43 years old, the course of disease 3 months～19 years, average 1.5 years.Physical data such as the sex of two groups of cases, age, the course of disease are through statistical procedures, and difference does not have significance (P＞0.05), has comparability.

2, diagnostic criteria (1) persistence or repeated relapsing upper abdominal pain or discomfort.(2) can have 1 or several of following symptom, promptly glutted after the meal, abdominal part flatulence, belch, early behind full, anorexia, nauseating, heartburn, the breastbone bitterly, pantothenic acid.(3) above-mentioned symptom existed more than 4 weeks.(4) gastroscope is got rid of organic diseases such as peptic ulcer, tumor, erosion, does not also have above-mentioned medical history.(5) laboratory, B ultrasonic, X ray examination are got rid of liver, gallbladder, pancreas and intestinal organic disease.(6) systemic diseases such as non-diabetic, connective tissue and hyperthyroidism.(7) no abdominal operation history.

3, Therapeutic Method treatment group adopts the Chinese medicine soup that is good for the stomach that expands of dispelling.Radix Ginseng 20g, Fructus Jujubae 15g, Pericarpium Citri tangerinae 11g, Rhizoma Cyperi 12g, Radix Curcumae 12g, Semen Raphani 11g, Semen Platycladi 17g, Fructus Citri 17g, Bulbus Allii Macrostemonis 12g.1 dose of every day, decocting divides and takes orally for 2 times.

The oral motilium of matched group (production of Xi'an Yang Sen pharmaceutical Co. Ltd) 10mg, every day 3 taking medicine before meal.

Two groups of patients note forming good living habit during treating, all avoid high fat diet, maror, raw food, and wine for giving off smoking is avoided overwork, avoids psychentonia, dispel misgivings, and use non-steroid antiinflammatory drug less as far as possible.15 days is 1 course of treatment, after 1 course of treatment 2 days at interval, and the 2nd course of treatment of row again.Finish relatively curative effect of back 2 courses of treatment.Adopt chi-square criterion.

4, curative effect determinate standard is by formula obtained therapeutic index to judge curative effect according to symptom total points before and after the treatment.Symptom total points x100% before therapeutic index (symptom total points before the treatment-treatment back symptom mark)/treatment.Therapeutic index＜25% is invalid; 26%～50% for taking a turn for the better; 51%～85% is produce effects;＞86% is clinical cure.

5, the therapeutic outcome treatment is added up curative effect after two courses of treatment, and 130 examples are organized in treatment, cure 51 examples (39.2%), produce effects 42 examples (32.3%), 32 examples that take a turn for the better (24.5%), invalid 5 examples (3.85%), total effective rate 96.2%; In matched group 120 examples, cure 32 examples (26.7%), produce effects 29 examples (24.2%), 24 examples that take a turn for the better (20.0%), invalid 21 examples (17.5%), total effective rate 82.8%; Two groups of cure rates, total effective rate differences have significance.

The specific embodiment

Embodiment one: take by weighing Radix Ginseng 20g, Fructus Jujubae 15g, Pericarpium Citri tangerinae 11g, Rhizoma Cyperi 12g, Radix Curcumae 12g, Semen Raphani 11g, Semen Platycladi 17g, Fructus Citri 17g, Bulbus Allii Macrostemonis 12g.1 dose of every day, decocting divides and takes orally for 2 times.

Embodiment two: take by weighing Radix Ginseng 15g, Fructus Jujubae 20g, Pericarpium Citri tangerinae 13g, Rhizoma Cyperi 10g, Radix Curcumae 15g, Semen Raphani 9g, Semen Platycladi 20g, Fructus Citri 15g, Bulbus Allii Macrostemonis 10g.1 dose of every day, decocting divides and takes orally for 2 times.

Embodiment three: take by weighing Radix Ginseng 25g, Fructus Jujubae 10g, Pericarpium Citri tangerinae 9g, Rhizoma Cyperi 15g, Radix Curcumae 10g, Semen Raphani 13g, Semen Platycladi 15g, Fructus Citri 20g, Bulbus Allii Macrostemonis 15g.1 dose of every day, decocting divides and takes orally for 2 times.

Claims

1. a Chinese medicine of treating functional dyspepsia soup that is good for the stomach that expands of dispelling is characterized in that dispel the expand soup that is good for the stomach of this Chinese medicine processed by following parts by weight of Chinese traditional medicine: Radix Ginseng 15-25 part, Fructus Jujubae 10-20 part, Pericarpium Citri tangerinae 9-13 part, Rhizoma Cyperi 10-15 part, Radix Curcumae 10-15 part, Semen Raphani 9-13 part, Semen Platycladi 15-20 part, Fructus Citri 15-20 part, Bulbus Allii Macrostemonis 10-15 part.

2. a kind of Chinese medicine of treating functional dyspepsia according to claim 1 soup that is good for the stomach that expands of dispelling is characterized in that dispel the expand soup that is good for the stomach of this Chinese medicine processed by following parts by weight of Chinese traditional medicine: 20 parts of Radix Ginsengs, 15 parts in Fructus Jujubae, 11 parts of Pericarpium Citri tangerinaes, 12 parts of Rhizoma Cyperis, 12 parts of Radix Curcumaes, 11 parts of Semen Raphanis, 17 parts of Semen Platycladi, 17 parts of Fructus Citris, 12 parts of Bulbus Allii Macrostemonis.