CN101233123B - 用于制备2-甲氧基羰甲基-6，6-二甲基-2-四氢吡喃羧酸的方法 - Google Patents

用于制备2-甲氧基羰甲基-6，6-二甲基-2-四氢吡喃羧酸的方法 Download PDF

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Publication number
CN101233123B
CN101233123B CN2006800258750A CN200680025875A CN101233123B CN 101233123 B CN101233123 B CN 101233123B CN 2006800258750 A CN2006800258750 A CN 2006800258750A CN 200680025875 A CN200680025875 A CN 200680025875A CN 101233123 B CN101233123 B CN 101233123B
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CN
China
Prior art keywords
acid
methyl
methoxycarbonylmethyl
dimethyl
heptenoate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN2006800258750A
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English (en)
Chinese (zh)
Other versions
CN101233123A (zh
Inventor
马斯蒙·法拉利
保罗·贝罗蒂
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Stragen Pharma SA
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Stragen Pharma SA
Erregierre SpA
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Publication of CN101233123A publication Critical patent/CN101233123A/zh
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Publication of CN101233123B publication Critical patent/CN101233123B/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/35—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing only non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
CN2006800258750A 2005-07-15 2006-07-14 用于制备2-甲氧基羰甲基-6，6-二甲基-2-四氢吡喃羧酸的方法 Expired - Fee Related CN101233123B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI2005A001352 2005-07-15
IT001352A ITMI20051352A1 (it) 2005-07-15 2005-07-15 Processo di preparazi0ne di acido 2-metossicarbonilmetil-6,6-dimetil-2-tetraidropiran carbossilico
PCT/EP2006/064273 WO2007009953A1 (en) 2005-07-15 2006-07-14 Process for preparing 2-methoxycarbonylmethyl-6,6-dimethyl-2- tetrahydropyran carboxylic acid

Publications (2)

Publication Number Publication Date
CN101233123A CN101233123A (zh) 2008-07-30
CN101233123B true CN101233123B (zh) 2011-05-11

Family

ID=36087589

Family Applications (1)

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CN2006800258750A Expired - Fee Related CN101233123B (zh) 2005-07-15 2006-07-14 用于制备2-甲氧基羰甲基-6，6-二甲基-2-四氢吡喃羧酸的方法

Country Status (13)

Country Link
US (1) US8008514B2 (https=)
EP (1) EP1907371B1 (https=)
JP (1) JP2009501196A (https=)
CN (1) CN101233123B (https=)
AT (1) ATE534640T1 (https=)
CY (1) CY1112967T1 (https=)
DK (1) DK1907371T3 (https=)
ES (1) ES2378081T3 (https=)
IT (1) ITMI20051352A1 (https=)
PL (1) PL1907371T3 (https=)
PT (1) PT1907371E (https=)
SI (1) SI1907371T1 (https=)
WO (1) WO2007009953A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103910659B (zh) * 2013-11-04 2016-05-11 迈克斯(如东)化工有限公司 2-硝基-4-甲磺酰基苯甲酸的精制方法及其中间体
WO2016182850A1 (en) 2015-05-08 2016-11-17 Albany Molecular Research, Inc. Methods and intermediates for the preparation of omacetaxine and cephalotaxine derivatives thereof
EP3275875A1 (en) 2016-07-28 2018-01-31 INDENA S.p.A. Dioxolanone intermediate useful in the synthesis of homoharringtonine
CN110577803B (zh) 2018-06-11 2021-11-26 3M创新有限公司 一种阻燃压敏胶粘合剂、阻燃压敏胶粘合片及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0377862A (ja) 1989-08-18 1991-04-03 Ono Pharmaceut Co Ltd ビシクロ［２．２．１］ヘプタン誘導体、その精製方法および製造方法
FR2776292B1 (fr) 1998-03-20 2004-09-10 Oncopharm Cephalotaxanes porteurs de chaine laterale et leur procede de synthese
JP2001163841A (ja) * 1999-09-30 2001-06-19 Dai Ichi Seiyaku Co Ltd 光学活性な２−（２，３，４―トリハロゲノアニリノ）−プロピオン酸誘導体の製法
WO2004096785A1 (ja) * 2003-04-25 2004-11-11 Nippon Chemiphar Co., Ltd. （２s，３s）－３－［［（１s）－１－イソブトキシメチル－３－メチルブチル］カルバモイル］オキシラン－２－カルボン酸の塩

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JP平3-77862A 1991.04.03

Also Published As

Publication number Publication date
PL1907371T3 (pl) 2012-09-28
SI1907371T1 (sl) 2012-04-30
CY1112967T1 (el) 2016-04-13
US8008514B2 (en) 2011-08-30
EP1907371B1 (en) 2011-11-23
ATE534640T1 (de) 2011-12-15
US20090043093A1 (en) 2009-02-12
ITMI20051352A1 (it) 2007-01-16
JP2009501196A (ja) 2009-01-15
ES2378081T3 (es) 2012-04-04
WO2007009953A1 (en) 2007-01-25
EP1907371A1 (en) 2008-04-09
CN101233123A (zh) 2008-07-30
DK1907371T3 (da) 2012-03-19
PT1907371E (pt) 2012-03-06

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Address before: St Paul, Italy

Co-patentee before: Stragen Pharma SA

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Termination date: 20140714

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