CN101229311A - Medicine for treating osteoporosis and preparing method thereof - Google Patents
Medicine for treating osteoporosis and preparing method thereof Download PDFInfo
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- CN101229311A CN101229311A CNA2008100561405A CN200810056140A CN101229311A CN 101229311 A CN101229311 A CN 101229311A CN A2008100561405 A CNA2008100561405 A CN A2008100561405A CN 200810056140 A CN200810056140 A CN 200810056140A CN 101229311 A CN101229311 A CN 101229311A
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- cortex eucommiae
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Abstract
The invention discloses a medicine used for treating osteoporosis and the preparation method thereof; rhizomadrynariae, cortex encomia, traditional Chinese medicine hyssop, papaya, Chinese yam, poria and peach kernel are taken as raw materials, and combined according to the theory of Chinese medicine. By using the comprehensive action of all components, the medicine treats bone mass loss, bone tissue micro structure retrogression, bone brittleness increasing and other osteoporosis syndromes, without toxic or side effects on human body; and the invention has the advantages of simple formula, easy production, low cost, obvious therapeutic effect and etc.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of the sclerotin evacuation and preparation method thereof, a kind of specifically is the osteoporotic medicine of treatment of feedstock production with the natural Chinese medicinal herb, the invention still further relates to the preparation method of this medicine.
Background technology
Osteoporotic cardinal symptom shows as osteodynia, height shortening, hunchback, and wherein most important complication is a fracture.There are 90% old women and 50% elderly men to suffer from this disease according to investigations approximately.The generation of senile osteoporosis is relevant with human endocrine imbalance, hypokinesia and bad life habits.Brainstrust is thought, and is not insignificant to the influence of people's quality of life and economic situation etc. though osteoporosis can directly not cause death, and the treatment osteoporosis should attract great attention so the early discovery disease takes appropriate measures.At drug treatment, it is first-selected replenishing the calcium amount, can't deal with problems on pathogenesis but replenish the calcium merely, because old people's intestinal increases along with the age the absorbability of calcium and goes down at all.The traditional Chinese medical science thinks that osteoporotic basic reason is " suffering from a deficiency of the kidney ", and the key of correcting calcium deficiency is the kidney invigorating.The kidney being the origin of congenital constitution, main store essential substances.Smart marrow, the marrow nourishing bone of giving birth to.Kidney is being dominated people's growth, growth, aging, death.Then marrow biochemistry is active for the kidney essense abundance, and skeleton is nourished and strong strong; Otherwise then the medullization source is weary exhausts for deficiency of kidney-essence, and the bone amount reduces and forms osteoporosis.
Great mass of data proves that Chinese medicine not only can improve the allomeric function of human body to osteoporotic treatment, and can alleviate sore waist and aching in the waist and the back, whole body osteodynia, and clinical diseases such as fatigue and weak can also improve sex hormone level, reduce losing of bone calcium.Simultaneously, senile symptom is also had greatly improved, improve the quality of life of middle-aged and elderly people greatly.Therefore, on this Research Significance, special development cost invention is to remedy the weak point of existing medicine in treatment.
Summary of the invention
The object of the present invention is to provide the osteoporotic medicine of a kind of treatment, this Chinese medicine preparation is aided with the spleen invigorating mind calming, blood circulation promoting and blood stasis dispelling based on the kidney invigorating bone strengthening.Prescription is rigorous, and the compatibility science is evident in efficacy, can bring into play curative effect of medication to a greater extent, takes effect obviously clinical safe in utilization having no side effect.
Another object of the present invention provides the preparation method of this medicine.
Among the we, the modern pharmacology effect shows that the Rhizoma Drynariae extracting solution deposits obvious facilitation to calcium, the phosphorus of the Embryo Gallus domesticus collagen base in the tissue culture, improves the alkaline phosphatase activities in the tissue, promote proteoglycan synthetic, and prove that promoting proteoglycan synthetic is the key factor that promotes calcification.The have some improvement function of chondrocyte of Rhizoma Drynariae tool is postponed western degeneration, is reduced the effect of osteoarthritis sickness rate.The osteomiosis complementary energy increases callus thickness, improves union of fracture quality etc.Radix Achyranthis Bidentatae is traditional traditional tonic medicine, but nourishing liver and kidney, but also strengthening the tendons and bones, end that the waist knee joint is tingle, removing blood stasis dysmenorrhea, conducting blood to flow downwards etc.The water extract of the Cortex Eucommiae is cultivated 48h at 0.4g/L and is had the strongest promotion cel l proliferation, shows that the big part of Cortex Eucommiae Semi-polarity may contain to directly act on osteoblastic active component.And Semen Persicae has the function of blood circulation promoting and blood stasis dispelling, with the mating reaction of above-mentioned a few flavor medicine, can make the vigor of osteocyte recover faster, reduces also and progressively stablizes sclerotin, thereby osteoporosis is eased.
For achieving the above object, the solution that the present invention adopts is the medicament of being made by following materials of weight proportions:
Rhizoma Drynariae 5-20 part Radix Achyranthis Bidentatae 5-20 part Rhizoma Dioscoreae 10-30 part
Cortex Eucommiae 10-30 part Fructus Chaenomelis 10-30 part Poria 10-30 part
Semen Persicae 5-20 part
The Chinese medicine preparation of above-mentioned treatment chronic pharyngitis is the medicament of being made by following materials of weight proportions:
15 parts of 12 portions of Rhizoma Dioscoreaes of 10 parts of Radix Achyranthis Bidentataes of Rhizoma Drynariae
14 parts in 15 parts of Poria of 18 portions of Fructus Chaenomeliss of the Cortex Eucommiae
12 parts in Semen Persicae
Above-mentioned medicament is the above a dosage form of any pharmaceutics.
Above-mentioned dosage form is an electuary.
By the electuary that following method is made, this preparation method is:
1) take by weighing Rhizoma Drynariae in the prescription ratio, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Rhizoma Dioscoreae, Poria and Semen Persicae decoct 2 times with 8-10 times of water gaging, and each 1-3 hour, add 6-8 times of water gaging again and decocted 1-2 hour, 2 extracting solution are merged, filter.
2) with the filtrate decompression cryoconcentration to extractum, be blended into appropriate amount of starch, dextrin, alcohol granulation.
3) with the preparation drying, sieve, be distributed into electuary, specification 5g/ bag.
Embodiment 1:
10 parts of 8 portions of Rhizoma Dioscoreaes of 8 parts of Radix Achyranthis Bidentataes of Rhizoma Drynariae
10 parts in 12 parts of Poria of 12 portions of Fructus Chaenomeliss of the Cortex Eucommiae
8 parts in Semen Persicae
Take by weighing Rhizoma Drynariae in the prescription ratio, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Rhizoma Dioscoreae, Poria and Semen Persicae decoct 2 times with 8 times of water gagings, and each 1 hour, add 6 times of water gagings again and decocted 1 hour, 2 extracting solution are merged, filter.The filtrate decompression cryoconcentration to extractum, is blended into appropriate amount of starch, dextrin, alcohol granulation.With the preparation drying, sieve, be distributed into electuary, specification 5g/ bag.
Drinking method: tear small package bag, instant is poured in the cup, add warm water to 100～200mL, promptly drinkable after mixing well.One time one bag, 2 times on the one.
Embodiment 2:
20 parts of 15 portions of Rhizoma Dioscoreaes of 15 parts of Radix Achyranthis Bidentataes of Rhizoma Drynariae
16 parts in 18 parts of Poria of 18 portions of Fructus Chaenomeliss of the Cortex Eucommiae
15 parts in Semen Persicae
Take by weighing Rhizoma Drynariae in the prescription ratio, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Rhizoma Dioscoreae, Poria and Semen Persicae decoct 2 times with 8 times of water gagings, and each 1 hour, add 6 times of water gagings again and decocted 1 hour, 2 extracting solution are merged, filter.The filtrate decompression cryoconcentration to extractum, is blended into appropriate amount of starch, dextrin, alcohol granulation.With the preparation drying, sieve, be distributed into electuary, specification 5g/ bag.
Drinking method: tear small package bag, instant is poured in the cup, add warm water to 100～200mL, promptly drinkable after mixing well.One time one bag, 2 times on the one.
Embodiment 3:
15 parts of 12 portions of Rhizoma Dioscoreaes of 12 parts of Radix Achyranthis Bidentataes of Rhizoma Drynariae
15 parts in 14 parts of Poria of 16 portions of Fructus Chaenomeliss of the Cortex Eucommiae
12 parts in Semen Persicae
Take by weighing Rhizoma Drynariae in the prescription ratio, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Rhizoma Dioscoreae, Poria and Semen Persicae decoct 2 times with 8 times of water gagings, and each 1 hour, add 6 times of water gagings again and decocted 1 hour, 2 extracting solution are merged, filter.The filtrate decompression cryoconcentration to extractum, is blended into appropriate amount of starch, dextrin, alcohol granulation.With the preparation drying, sieve, be distributed into electuary, specification 5g/ bag.
Drinking method: tear small package bag, instant is poured in the cup, add warm water to 100～200mL, promptly drinkable after mixing well.One time one bag, 2 times on the one.
Claims (6)
1. treat osteoporotic medicine for one kind, it is characterized in that its raw material components weight proportion is:
Rhizoma Drynariae 5-20 part Radix Achyranthis Bidentatae 5-20 part Rhizoma Dioscoreae 10-30 part
Cortex Eucommiae 10-30 part Fructus Chaenomelis 10-30 part Poria 10-30 part
Semen Persicae 5-20 part
2. according to the osteoporotic medicine of claim 1 described a kind of treatment, it is characterized in that the more excellent proportioning of each component of raw material is:
Rhizoma Drynariae 8-15 part Radix Achyranthis Bidentatae 8-15 part Rhizoma Dioscoreae 10-20 part
Cortex Eucommiae 10-20 part Fructus Chaenomelis 10-20 part Poria 10-20 part
Semen Persicae 8-15 part
3. according to the osteoporotic medicine of claim 1 described a kind of treatment, it is characterized in that the best proportioning of each component of raw material is:
15 parts of 12 portions of Rhizoma Dioscoreaes of 10 parts of Radix Achyranthis Bidentataes of Rhizoma Drynariae
14 parts in 15 parts of Poria of 18 portions of Fructus Chaenomeliss of the Cortex Eucommiae
12 parts in Semen Persicae
4. each a kind of according to claim 1-3 treats the medicine that sclerotin is evacuated, and it is characterized in that: described medicament is the above a dosage form of any pharmaceutics.
5. according to claim 4 described a kind of medicines that sclerotin is evacuated for the treatment of, it is characterized in that: described dosage form is an electuary.
6. according to claim 5 described a kind of preparation methoies for the treatment of the medicine of sclerotin evacuation, it is characterized in that: 1) take by weighing Rhizoma Drynariae, the Cortex Eucommiae, Radix Achyranthis Bidentatae in the prescription ratio, Fructus Chaenomelis, Rhizoma Dioscoreae, Poria and Semen Persicae decoct 2 times with 8-10 times of water gaging, each 1-3 hour, add 6-8 times of water gaging again and decocted 1-2 hour, 2 extracting solution are merged, filter.
2) with the filtrate decompression cryoconcentration to extractum, be blended into appropriate amount of starch, dextrin, alcohol granulation.
3) with the preparation drying, sieve, be distributed into electuary, specification 5g/ bag.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100561405A CN101229311A (en) | 2008-01-14 | 2008-01-14 | Medicine for treating osteoporosis and preparing method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100561405A CN101229311A (en) | 2008-01-14 | 2008-01-14 | Medicine for treating osteoporosis and preparing method thereof |
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| CN101229311A true CN101229311A (en) | 2008-07-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2008100561405A Pending CN101229311A (en) | 2008-01-14 | 2008-01-14 | Medicine for treating osteoporosis and preparing method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102988687A (en) * | 2012-11-27 | 2013-03-27 | 高金菊 | Medicinal liquor for enhancing fracture healing |
| CN108402460A (en) * | 2018-05-11 | 2018-08-17 | 中国医科大学 | A kind of multifunctional food composition and preparation method thereof increasing bone density |
-
2008
- 2008-01-14 CN CNA2008100561405A patent/CN101229311A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102988687A (en) * | 2012-11-27 | 2013-03-27 | 高金菊 | Medicinal liquor for enhancing fracture healing |
| CN108402460A (en) * | 2018-05-11 | 2018-08-17 | 中国医科大学 | A kind of multifunctional food composition and preparation method thereof increasing bone density |
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Open date: 20080730 |