CN101180391A - 因子XIIa形式 - Google Patents

因子XIIa形式 Download PDF

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Publication number
CN101180391A
CN101180391A CN200680007279.XA CN200680007279A CN101180391A CN 101180391 A CN101180391 A CN 101180391A CN 200680007279 A CN200680007279 A CN 200680007279A CN 101180391 A CN101180391 A CN 101180391A
Authority
CN
China
Prior art keywords
factor
disease
plasma thromboplastin
thromboplastin antecedent
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200680007279.XA
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English (en)
Chinese (zh)
Inventor
戴维·约翰·普里查德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axis Shield Diagnostics Ltd
Original Assignee
Axis Shield Diagnostics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axis Shield Diagnostics Ltd filed Critical Axis Shield Diagnostics Ltd
Publication of CN101180391A publication Critical patent/CN101180391A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6451Coagulation factor XIIa (3.4.21.38)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21038Coagulation factor XIIa (3.4.21.38)

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200680007279.XA 2005-01-11 2006-01-10 因子XIIa形式 Pending CN101180391A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0500487.4A GB0500487D0 (en) 2005-01-11 2005-01-11 Forms of factor XIIa
GB0500487.4 2005-01-11

Publications (1)

Publication Number Publication Date
CN101180391A true CN101180391A (zh) 2008-05-14

Family

ID=34203898

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200680007279.XA Pending CN101180391A (zh) 2005-01-11 2006-01-10 因子XIIa形式

Country Status (9)

Country Link
US (1) US20080274477A1 (https=)
EP (1) EP1848799A2 (https=)
JP (1) JP2008526937A (https=)
CN (1) CN101180391A (https=)
AU (1) AU2006205700A1 (https=)
BR (1) BRPI0606307A2 (https=)
CA (1) CA2609109A1 (https=)
GB (1) GB0500487D0 (https=)
WO (1) WO2006075142A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104345154A (zh) * 2014-08-22 2015-02-11 北京蛋白质组研究中心 一种检测多肿瘤相关“多肽-蛋白组合式标志物”的双抗体夹心试剂盒
CN104177503B (zh) * 2014-08-22 2018-04-13 北京蛋白质组研究中心 一种激酶通路相关“多肽‑蛋白组合式”标志物及定量检测技术
CN108137705A (zh) * 2015-07-21 2018-06-08 戴埃克斯有限公司 一种因子xiia的单克隆抗体抑制剂
US11390687B2 (en) 2015-01-02 2022-07-19 Takeda Pharmaceutical Company Limited Bispecific antibodies against plasma kallikrein and Factor XII

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0607515D0 (en) * 2006-04-13 2006-05-24 Axis Shield Diagnostics Ltd Anti-factor xlla therapy
ES3005912T3 (en) * 2011-07-22 2025-03-17 Csl Behring Gmbh Inhibitory anti-factor xii/xiia monoclonal antibodies and their uses
WO2013190041A1 (en) * 2012-06-22 2013-12-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and kits for predicting the survival time of post acute myocardial infarction patients

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901859D0 (en) * 1989-01-27 1989-03-15 Shield Diagnostics Limited Diagnostic test
US20060024745A1 (en) * 2002-12-20 2006-02-02 Pritchard David J Variants of factor XllA

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104345154A (zh) * 2014-08-22 2015-02-11 北京蛋白质组研究中心 一种检测多肿瘤相关“多肽-蛋白组合式标志物”的双抗体夹心试剂盒
CN104345154B (zh) * 2014-08-22 2016-10-26 北京蛋白质组研究中心 一种检测多肿瘤相关“多肽-蛋白组合式标志物”的双抗体夹心试剂盒
CN104177503B (zh) * 2014-08-22 2018-04-13 北京蛋白质组研究中心 一种激酶通路相关“多肽‑蛋白组合式”标志物及定量检测技术
US11390687B2 (en) 2015-01-02 2022-07-19 Takeda Pharmaceutical Company Limited Bispecific antibodies against plasma kallikrein and Factor XII
US12240918B2 (en) 2015-01-02 2025-03-04 Takeda Pharmaceutical Company Limited Bispecific antibodies against plasma kallikrein and factor XII
CN108137705A (zh) * 2015-07-21 2018-06-08 戴埃克斯有限公司 一种因子xiia的单克隆抗体抑制剂
CN108137705B (zh) * 2015-07-21 2022-11-08 武田药品工业株式会社 一种因子xiia的单克隆抗体抑制剂
US12415866B2 (en) 2015-07-21 2025-09-16 Takeda Pharmaceutical Company Limited Monoclonal antibody inhibitor of Factor XIIa

Also Published As

Publication number Publication date
WO2006075142A3 (en) 2006-09-14
EP1848799A2 (en) 2007-10-31
JP2008526937A (ja) 2008-07-24
US20080274477A1 (en) 2008-11-06
CA2609109A1 (en) 2006-07-20
WO2006075142A2 (en) 2006-07-20
GB0500487D0 (en) 2005-02-16
BRPI0606307A2 (pt) 2009-06-16
AU2006205700A1 (en) 2006-07-20

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Open date: 20080514